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BigScience Biomedical Datasets 111

200

366

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Awakening-free nights percentage improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

201

338

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Pre-dose inspiratory capacity?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

202

360

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Overall use of daily rescue medication improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

203

420

1784771

Compared to Prostaglandin gel what was the result of Prostaglandin gel plus hygroscopic cervical dilators on Infection?

multiple_choice

The combined therapy group had a higher infection rate than the prostaglandin-only group (59% vs. 12%, P = 0.003).

204

457

3446002

Compared to control group what was the result of single dose of 50 mg/kg clofibrate on Total serum bilirubin level?

multiple_choice

On serial daily examination during phototherapy and up to 2 days after that no problems or side effects were observed. Also for a period of two months no complication was detected.

205

415

2575601

Compared to Pentobarbital what was the result of Thiopental on Sepsis related Organ-Failure Assessment (SOFA) baseline scores?

multiple_choice

There were no differences between groups with respect to the incidence of infections, Sepsis related Organ-Failure Assessment (SOFA) scores before initiation of treatment,

206

242

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Higher-order aberrations at 6 months?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

207

459

1913177

Compared to prosthetic repair with e-PTFE patch (PR) what was the result of components separation technique (CST) on Wound complications?

multiple_choice

Wound complications were found in 10 of 19 patients after CST and 13 of 18 patients after PR.

208

280

2361806

Compared to Etoposide with 5-fluorouracil plus leucovorin (ELF) what was the result of Irinotecan with high-dose 5-fluorouracil plus leucovorin (ILF) on Clinical response rates at 14 weeks?

multiple_choice

For ILF and ELF, respectively, median progression-free survival was 4.5 vs 2.3 months, time to treatment failure was 3.6 vs 2.2 months (P=0.4542), and overall survival was 10.8 vs 8.3 months (P=0.2818).

209

236

3090298

Compared to Pre-surgery baseline what was the result of Thin-flap laser in situ keratomileusis (LASIK) on Contrast sensitivity?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

210

356

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Cough score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

211

451

2720945

Compared to placebo what was the result of cineole on Quality of life?

multiple_choice

The difference between the two treatment groups was neither clinically relevant nor statistically significant. Safety examinations of the global assessment showed no difference between the two treatment groups.

212

465

3387601

Compared to intravenous immunoglobulin (IVIG) what was the result of plasma exchange (PE) on Pediatric Intensive Care Unit (PICU) stay?

multiple_choice

Examining the treatment groups separately, the significant negative correlation remained for the PE group (p-value = 0.037) and not for the IVIG group (p-value 0.132)

213

337

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Pre-dose inspiratory capacity?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

214

318

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Peak expiratory flow in the morning and evening ?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

215

475

2447617

Compared to placebo what was the result of progesterone on The modified Functional Independence Measure scores?

multiple_choice

The percentage of favorable outcome was 58% for the patients who were given progesterone and was 42% in the placebo group (P = 0.048). Forty-one percent of patients who were given progesterone and 57% of the placebo group exhibited an unfavorable outcome (P = 0.048).

216

219

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline systolic dysfunction?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

217

340

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on 1-hour post-dose inspiratory capacity mean improvements from baseline to the average over the randomized treatment period ?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

218

243

2922723

Compared to Usual airway clearance techniques what was the result of High frequency chest wall oscillation on Sputum expectoration during a single session?

multiple_choice

Patients scored the efficacy of their usual ACT significantly higher than for HFCWO (mean difference 14 mm; p=0.002).

219

270

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Ulcer mean diameter?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

220

408

2575601

Compared to Pentobarbital what was the result of Thiopental on Refractory intracranial pressure?

multiple_choice

There were no differences between groups with respect to the incidence of infections, Sepsis related Organ-Failure Assessment (SOFA) scores before initiation of treatment,

221

327

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Baseline-adjusted average 12-hour FEV1 at end of treatment?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

222

357

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Sputum score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

223

230

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Uncorrected distance visual acuity at 3 months?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

224

436

1201146

Compared to vehicle control solution (carrier with no diclofenac) what was the result of topical diclofenac solution (Pennsaid®) on Pain on walking?

multiple_choice

There was a significantly greater improvement in score with topical diclofenac compared to vehicle control (Table 2) for pain on walking (-1.2 vs. -0.8; p = 0.014).

225

396

2690844

Compared to Midline incision what was the result of Transverse incision on Average patient's lenght?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

226

223

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline angiotensin II receptor blockers (ARBs) intake?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

227

253

1831737

Compared to Communities that received standard Government services what was the result of Communities that received additional education and preventive measures on HIV-1 prevalence?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

228

351

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Improvements in St. George's Respiratory Questionnaire overall score?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

229

222

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline digoxin intake?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

230

329

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Baseline-adjusted average 12-hour FEV1 on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

231

388

2690844

Compared to Midline incision what was the result of Transverse incision on Incisional hernia apparition at follow-up?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

232

444

1468428

Compared to no enema what was the result of 1 litre saline enema on Median labour time?

multiple_choice

We found no significant differences in puerperal or neonatal infection rates (Puerperal infection: 41/190 [22%] with enema v 26/182 [14%] without enema; RR 0.66 CI 95%: 0.43 to 1.03; neonatal infection 38/191 [20%] with enema v 40/179 [22%] without enema; RR 1.12, 95% CI 95% 0.76 to 1.66)

233

462

1876597

Compared to artemether-lumefantrine what was the result of dihydroartemisinin-piperaquine on the risk of recurrent parasitemia due to possible recrudescence?

multiple_choice

Overall, there was no difference in the proportion of study participants who experienced any adverse event of moderate or greater severity between the DP (46%) and AL (42%) treatment groups (p = 0.47).

234

394

2690844

Compared to Midline incision what was the result of Transverse incision on Analgesics use?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

235

311

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Time to discontinuation?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

236

332

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Baseline-adjusted average 12-hour FEV1 on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

237

221

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline angiotensin-converting enzyme (ACE) inhibitors intake?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

238

235

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Contrast sensitivity?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

239

352

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Improvements in St. George's Respiratory Questionnaire overall score?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

240

418

1784771

Compared to Prostaglandin gel what was the result of Prostaglandin gel plus hygroscopic cervical dilators on Baseline demographic differences?

multiple_choice

The combined therapy group had a higher infection rate than the prostaglandin-only group (59% vs. 12%, P = 0.003).

241

453

2720945

Compared to placebo what was the result of cineole on Trouble in breathing, dyspnea in the morning and dyspnea at rest?

multiple_choice

The difference between the two treatment groups was neither clinically relevant nor statistically significant. Safety examinations of the global assessment showed no difference between the two treatment groups.

242

321

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Peak expiratory flow in the morning and evening ?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

243

262

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on High-risk sexual behaviour?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

244

378

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on 24-hour urinary cortisol at end of treatment?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

245

349

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on Amount of exacerbations per patient-treatment year?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

246

312

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Pre-dose FEV1 improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

247

372

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Overall use of daily rescue medication improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

248

267

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Postoperative complications?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

249

249

2922723

Compared to Usual airway clearance techniques what was the result of High frequency chest wall oscillation on Visual analogue scale scores for urinary leakage?

multiple_choice

Patients scored the efficacy of their usual ACT significantly higher than for HFCWO (mean difference 14 mm; p=0.002).

250

272

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Median loss of blood?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

251

404

2690844

Compared to Midline incision what was the result of Transverse incision on Hospital stay?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

252

320

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on Peak expiratory flow in the morning and evening ?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

253

469

2430614

Compared to artemether-lumefantrine (AL) and and Artesunate+chlorproguanil-dapsone (AS+CD) what was the result of Artesunate+amodiaquine (AS+AQ) on the parasitological and clinical failure rate at day 28 post treatment?

multiple_choice

the parasitological and clinical failure rate at day 28 post treatment (PCF28) was lower in the AS+AQ group compared to the AL or AS+CD groups (corrected for re-infections: 6.6% vs 13.8% and 13.8% respectively, p = 0.08; uncorrected: 14.6% vs 27.6% and 28.1% respectively, p = 0.005).

254

611

5577662

Compared to dose of 0.25 mg, 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated placebo (4:1 ratio) what was the result of receive a dose of 0.25 mg (1:1:1 ratio) and then allocated to active treatment (CCH) on percentage changes in area?

multiple_choice

percentage changes in area were significantly greater with CCH 0.40 mg (−80.1%, P = 0.0002) and CCH 0.60 mg (−78.2%, P = 0.0003), but not CCH 0.25 mg (−58.3%, P = 0.079), versus placebo (−42.2%) at post-treatment Week 8.

255

578

4577567

Compared to free stride frequency what was the result of stride frequency manipulation on internal work?

multiple_choice

nversely, a decreased stride frequency (4.44%; p<0.0001) and internal work (7.09%; p<0.05) were found.

256

619

4139977

Compared to similar placebo, twice daily after a meal for 14 consecutive days what was the result of receive a probiotic compound containing seven bacteria species including Lactobacillus strains, Bifidobacterium strains and Streptococcus thermophiles on Improvement in bowel habit?

multiple_choice

mprovement in bowel habit was observed in 33.3% of the probiotic and 36.5% of the placebo group (P = 0.910).

257

608

5577662

Compared to dose of 0.25 mg, 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated placebo (4:1 ratio) what was the result of receive a dose of 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated to active treatment (CCH) on percentage changes in area?

multiple_choice

percentage changes in area were significantly greater with CCH 0.40 mg (−80.1%, P = 0.0002) and CCH 0.60 mg (−78.2%, P = 0.0003), but not CCH 0.25 mg (−58.3%, P = 0.079), versus placebo (−42.2%) at post-treatment Week 8.

258

595

4819709

Compared to surgery what was the result of Ultrasound‐guided foam sclerotherapy on Full return to normal work/employment?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

259

593

4819709

Compared to surgery what was the result of Ultrasound‐guided foam sclerotherapy on Wearing clothes that show the legs?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

260

551

125315

Compared to received only standard therapy for sepsis what was the result of received standard therapy for sepsis and physiological-dose steroid therapy for 10 days; on The median stay in hospital?

multiple_choice

The median stay in hospital was 14 days (95% CI 11.09–20.08) in the steroid therapy group and 13 days (95% CI 10.13–16.37) in the standard therapy group (P = 0.406).

261

556

4785315

Compared to standard maternity care what was the result of additional lay support (in this instance Pregnancy Outreach Workers, POWs) on Postnatal depression (Edinburgh Postnatal Depression Scale17 EPDS)?

multiple_choice

no significant differences were seen in the mean EPDS (mean difference (MD) −0.59 (95% CI −1.24 to 0.06)) for all the women recruited

262

519

1261533

Compared to Mefloquine-artesunate what was the result of Artemether-lumefantrine on Decrease in haematocrit level at day 7?

multiple_choice

The mean (SD) decrease in haematocrit value at day seven from baseline was greater in the group receiving MAS3 than in the ALN group: 9.3% (SD

263

620

4139977

Compared to similar placebo, twice daily after a meal for 14 consecutive days what was the result of receive a probiotic compound containing seven bacteria species including Lactobacillus strains, Bifidobacterium strains and Streptococcus thermophiles on quality-of-life ?

multiple_choice

mprovement in bowel habit was observed in 33.3% of the probiotic and 36.5% of the placebo group (P = 0.910).

264

583

4819709

Compared to surgery what was the result of Ultrasound‐guided foam sclerotherapy on Bending the legs without discomfort?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

265

599

4819709

Compared to Ultrasound‐guided foam sclerotherapy what was the result of Endovenous laser ablation on walking short distances without discomfort, walking long distances, looking after children, full return to normal work/employment?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

266

582

3800940

Compared to Godugdha sodhit Langali moola with honey for external application what was the result of Gomutra sodhit Langali moola with honey for external application on Indralupta is a unique, idiopathic, non-cictricial, non-inflammatory alopecia, presents as discoid areas of hair loss.?

multiple_choice

It was observed that after 60 days of treatment with Gomutrashodhit Langlimool in Group A there was reduction in Hair fall which is statistically highly significant (P<0.001) and highly significant improvement was observed in reducing dandruff.(p<0.001). Where as in Group B Godugdashodhit Langlimool application reduced the hair fall to statistically significant level (p<0.01) and statistically significant in reducing the dandruff in patient with Indralupta (P<0.01).

267

560

2888205

Compared to fibromyalgia (FM) education control (FME) group - received information and support what was the result of lifestyle physical activity (LPA) - 30 minutes of self-selected moderate-intensity LPA, five to seven days per week on pain?

multiple_choice

At post-testing, compared to the FME group, the LPA group reported significant reductions in the FIQ score (P = .032; Cohen's d = .53) and in pain (P = .006; Cohen's d = .67).

268

485

2806484

Compared to Facility-based HIV-care strategy what was the result of Home-based HIV-care strategy on Virological failure?

multiple_choice

Rates of detection of plasma viral loads of more than 500 copies per mL after a 6-month visit were much the same in both groups.

269

561

2888205

Compared to fibromyalgia (FM) education control (FME) group - received information and support what was the result of lifestyle physical activity (LPA) - 30 minutes of self-selected moderate-intensity LPA, five to seven days per week on six-minute walk test?

multiple_choice

At post-testing, compared to the FME group, the LPA group reported significant reductions in the FIQ score (P = .032; Cohen's d = .53) and in pain (P = .006; Cohen's d = .67).

270

534

3198285

Compared to high-fiber moderate-GI diet (HF) (target glycemic index GI ~60) what was the result of low–glycemic index diet (target glycemic index [GI] ~50) on low–glycemic index?

multiple_choice

The LGI group achieved a modestly lower GI than the HF group (mean ± SEM 47 ± 1 vs. 53 ± 1; P < 0.001).

271

589

4819709

Compared to surgery what was the result of Ultrasound‐guided foam sclerotherapy on Having a bath or shower?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

272

601

2891743

Compared to glucose 5% solution what was the result of glycine 1.5% solution as irrigating fluid on transurethral resection (TUR) syndrome?

multiple_choice

TUR syndrome 17* 0 0

273

510

1964758

Compared to BioModular® shoulder prosthesis what was the result of Initial Nottingham TSR design prosthesis on 8-year survivorship in patients with osteoarthritis?

multiple_choice

The initial Nottingham TSR prostheses showed higher eight year survivorship than BioModular® prostheses in patients with OA (p < 0.01). Survivorship of the BioModular® prosthesis in patients with primary osteoarthritis was 70.9% and 64.3% at five and eight years respectively and for the initial Nottingham TSR these values were 84.5% and 80.4%

274

602

2891743

Compared to normal saline 0.9% solution what was the result of glycine 1.5% solution as irrigating fluid on transurethral resection (TUR) syndrome?

multiple_choice

TUR syndrome 17* 0 0

275

512

2829413

Compared to Atorvastatin what was the result of Rosuvastatin on Levels of LDL cholesterol after 6 weeks of treatment?

multiple_choice

After 6 weeks of treatment, greater reductions in total cholesterol (- 35.94 ± 11.38 vs. - 30.07 ± 10.46%, p < 0.001), LDL-C (48.04 ± 14.45 vs. 39.52 ± 14.42%, p < 0.001), non-high-density lipoprotein cholesterol (- 42.93 ± 13.15 vs. - 35.52 ± 11.76%, p < 0.001), and apolipoprotein-B (- 38.7 ± 18.85 vs. - 32.57 ± 17.56%, p = 0.002) levels were observed in the rosuvastatin group as compared to the atorvastatin group.

276

610

5577662

Compared to dose of 0.25 mg, 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated placebo (4:1 ratio) what was the result of receive a dose of 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated to active treatment (CCH) on global assessment of improvement?

multiple_choice

percentage changes in area were significantly greater with CCH 0.40 mg (−80.1%, P = 0.0002) and CCH 0.60 mg (−78.2%, P = 0.0003), but not CCH 0.25 mg (−58.3%, P = 0.079), versus placebo (−42.2%) at post-treatment Week 8.

277

522

1261533

Compared to Mefloquine-artesunate what was the result of Artemether-lumefantrine on P. vivax parasitaemia diagnosed during follow up?

multiple_choice

The mean (SD) decrease in haematocrit value at day seven from baseline was greater in the group receiving MAS3 than in the ALN group: 9.3% (SD

278

531

2364680

Compared to opening subcutaneous tissues with scalpel what was the result of opening subcutaneous tissues with electrocautery on wound problem?

multiple_choice

Fifteen of 380 women (3.9%) developed a wound problem; six had scalpel and nine had electrosurgical subcutaneous incisions (P = 0.4).

279

491

2363351

Compared to Cisplatin and Cyclophosphamide what was the result of Cisplatin and Cyclophosphamide, plus subcutaneous IFN-γ on Overall survival at 3 years?

multiple_choice

Three-year overall survival was 58% and 74% accordingly (n.s., median not yet reached).

280

536

3198285

Compared to high-fiber moderate-GI diet (HF) (target glycemic index GI ~60) what was the result of low–glycemic index diet (target glycemic index [GI] ~50) on Birth weight (kg), Birth weight centile, Small for gestational age, Macrosomia, Infant head circumference, Infant length (cm), Ponderal index (kg/m3), Maternal weight gain (kg), Insulin treatment, Emergency caesarean?

multiple_choice

The LGI group achieved a modestly lower GI than the HF group (mean ± SEM 47 ± 1 vs. 53 ± 1; P < 0.001).

281

498

2364533

Compared to Placebo what was the result of Erythromycin on Preterm delivery?

multiple_choice

When the results were examined without regard to study site, erythromycin had little impact on reducing low birth weight (8% vs. 11%, P = 0.4) or preterm delivery (13% vs. 15%, P = 0.7)

282

487

2806484

Compared to Facility-based HIV-care strategy what was the result of Home-based HIV-care strategy on Costs for the health service?

multiple_choice

Rates of detection of plasma viral loads of more than 500 copies per mL after a 6-month visit were much the same in both groups.

283

609

5577662

Compared to dose of 0.25 mg, 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated placebo (4:1 ratio) what was the result of receive a dose of 0.25 mg, 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated to active treatment (CCH) on Mean change in nodular consistency and hardness?

multiple_choice

percentage changes in area were significantly greater with CCH 0.40 mg (−80.1%, P = 0.0002) and CCH 0.60 mg (−78.2%, P = 0.0003), but not CCH 0.25 mg (−58.3%, P = 0.079), versus placebo (−42.2%) at post-treatment Week 8.

284

591

4819709

Compared to surgery what was the result of Ultrasound‐guided foam sclerotherapy on Doing housework?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

285

539

2722000

Compared to received antibiotics only when infection was suspected or established what was the result of received antibiotics treatment after randomization with intravenous cefotaxime 2 gram q 8 hr for 7 days on rebleeding?

multiple_choice

The rebleeding rate in the prophylactic group was significantly lower than that in the on-demand group (21/62, 33.9% vs. 36/58, 62.1%, p=0.004).

286

543

2650992

Compared to control group what was the result of fibrin glue group (glue sprayed onto the axillary dissection site) on The mean drainage duration?

multiple_choice

The mean drainage duration was 3.3 days for the fibrin glue group and 3.8 days for the control group (p=0.067).

287

533

3221331

Compared to set a quit date and received a general health video message sent to their phone every 2 weeks. what was the result of an automated package of video and text messages over 6 months that was tailored to self-selected quit date, role model, and timing of messages. Extra messages were available on demand to beat cravings and address lapses. on did not attempt to quit smoking at all?

multiple_choice

At 6 months all participants were asked how many quit attempts they had made during the study period. In the intervention group 7/73 respondents (9.6%) and in the control group 4/81 (4.9%) (P = .3) stated they did not attempt to quit at all, but the majority of respondents in both groups made multiple quit attempts.

288

314

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Pre-dose FEV1 improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

289

333

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on Baseline-adjusted average 12-hour FEV1 on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

290

335

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Mean FEV1 at 12 hours at end of treatment?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

291

390

2690844

Compared to Midline incision what was the result of Transverse incision on Better cosmetic appearance of the incision as subjectively assessed by surgeons?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

292

359

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Awakening-free nights percentage improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

293

425

1187893

Compared to No exercise what was the result of Exercise on SF-36 Mental Component Summary scale at 6 weeks?

multiple_choice

In the exercise group, an improvement was seen at 6 weeks in the KOOS subscale quality of life compared to the control group (mean change 4.0 vs. -0.7, p = 0.05). The difference between groups was still persistent at 6 months (p = 0.02).

294

348

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Amount of exacerbations per patient-treatment year?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

295

330

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Mean FEV1 at 12 hours on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

296

331

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on Mean FEV1 at 12 hours on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

297

234

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on 1 line or more of CDVA at 6 months?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

298

325

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Mean FEV1 at 12 hours at end of treatment?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

299

383

2721929

Compared to Bladder training only (BT) what was the result of Bladder training plus tolterodine (Co) on Micturition frequency?

multiple_choice

Mean urgency score decreased by 44.8%, 62.2% and 60.2% in the BT, To, and Co groups, respectively, and the improvement was significantly greater in the To and Co groups than in the BT group (p<0.05 for each).