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BigScience Biomedical Datasets 111

100

109

2871176

Compared to Placebo plus glimepiride what was the result of Rosiglitazone plus glimepiride on HbA1c level at 26 weeks?

multiple_choice

The proportion of subjects experiencing minor hypoglycaemia during the trial was lowest with placebo (i.e. glimepiride monotherapy 2.6%; 0.17 events/subject-year), comparable with liraglutide 0.6 mg (5.2%, 0.17 events/subject-year) and rosiglitazone (4.3%, 0.12 events/subject-year) groups and similar between the liraglutide 1.2 mg (9.2%, 0.51 events/subject-year) and liraglutide 1.8 mg (8.1%, 0.47 events/subject-year) treatment groups. Incidence was higher with liraglutide 1.2 mg (P = 0.0024) and 1.8 mg (P = 0.0065) compared with rosiglitazone and liraglutide 1.2 mg compared with placebo (P = 0.048), occurring in the setting of lower mean HbA1c values.

101

146

2871176

Compared to Rosiglitazone plus glimepiride what was the result of Liraglutide (all doses) plus glimepiride on Decreases in diastolic blood pressure?

multiple_choice

The proportion of subjects experiencing minor hypoglycaemia during the trial was lowest with placebo (i.e. glimepiride monotherapy 2.6%; 0.17 events/subject-year), comparable with liraglutide 0.6 mg (5.2%, 0.17 events/subject-year) and rosiglitazone (4.3%, 0.12 events/subject-year) groups and similar between the liraglutide 1.2 mg (9.2%, 0.51 events/subject-year) and liraglutide 1.8 mg (8.1%, 0.47 events/subject-year) treatment groups. Incidence was higher with liraglutide 1.2 mg (P = 0.0024) and 1.8 mg (P = 0.0065) compared with rosiglitazone and liraglutide 1.2 mg compared with placebo (P = 0.048), occurring in the setting of lower mean HbA1c values.

102

205

4106715

Compared to placebo what was the result of low Ab group on Prolonged abstinence from smoking rates to 12 months?

multiple_choice

3'AmNic-rEPA recipients with the highest serum anti-nicotine antibody response (top 30% by AUC) were significantly more likely to attain 8 weeks continuous abstinence from weeks 19 through 26 than the placebo recipients (24.6% vs. 12.0%, p=0.024, OR=2.69, 95% CI, 1.14–6.37).

103

93

2944158

Compared to staff inclination replacement what was the result of routine replacement on infiltration?

multiple_choice

For individual IVD dwell times, the clinically indicated group devices had a median dwell time of 85 hours (quartiles 51 and 121 hours), and those replaced routinely had a median dwell time of 71 hours (quartiles 48 and 90 hours) (P < 0.001).

104

192

1852268

Compared to Intravenous piperacillin–tazobactam, 3.375 g every 6 hours what was the result of Inravenous ertapenem, 1 g once a day on obstetric/postpartum infection or gynecologic/postoperative infection?

multiple_choice

At the primary efficacy endpoint 2–4 weeks post therapy, 93.9% of patients who received ertapenem and 91.5% of those who received piperacillin–tazobactam were cured (95% confidence interval for the difference, adjusting for strata, –4% to 8.8%), indicating that cure rates for both treatment groups were equivalent.

105

110

2871176

Compared to Placebo plus glimepiride what was the result of Liraglutide (1.2 mg) plus glimepiride on Patients reaching HbA1c goals less than 7.0% and equal or less than 6.5%?

multiple_choice

The proportion of subjects experiencing minor hypoglycaemia during the trial was lowest with placebo (i.e. glimepiride monotherapy 2.6%; 0.17 events/subject-year), comparable with liraglutide 0.6 mg (5.2%, 0.17 events/subject-year) and rosiglitazone (4.3%, 0.12 events/subject-year) groups and similar between the liraglutide 1.2 mg (9.2%, 0.51 events/subject-year) and liraglutide 1.8 mg (8.1%, 0.47 events/subject-year) treatment groups. Incidence was higher with liraglutide 1.2 mg (P = 0.0024) and 1.8 mg (P = 0.0065) compared with rosiglitazone and liraglutide 1.2 mg compared with placebo (P = 0.048), occurring in the setting of lower mean HbA1c values.

106

100

2871176

Compared to Rosiglitazone plus glimepiride what was the result of Liraglutide (1.2 mg) plus glimepiride on HbA1c level at 26 weeks?

multiple_choice

The proportion of subjects experiencing minor hypoglycaemia during the trial was lowest with placebo (i.e. glimepiride monotherapy 2.6%; 0.17 events/subject-year), comparable with liraglutide 0.6 mg (5.2%, 0.17 events/subject-year) and rosiglitazone (4.3%, 0.12 events/subject-year) groups and similar between the liraglutide 1.2 mg (9.2%, 0.51 events/subject-year) and liraglutide 1.8 mg (8.1%, 0.47 events/subject-year) treatment groups. Incidence was higher with liraglutide 1.2 mg (P = 0.0024) and 1.8 mg (P = 0.0065) compared with rosiglitazone and liraglutide 1.2 mg compared with placebo (P = 0.048), occurring in the setting of lower mean HbA1c values.

107

204

4106715

Compared to placebo what was the result of high Ab group on Prolonged abstinence from smoking rates to 12 months?

multiple_choice

3'AmNic-rEPA recipients with the highest serum anti-nicotine antibody response (top 30% by AUC) were significantly more likely to attain 8 weeks continuous abstinence from weeks 19 through 26 than the placebo recipients (24.6% vs. 12.0%, p=0.024, OR=2.69, 95% CI, 1.14–6.37).

108

138

2871176

Compared to Placebo plus glimepiride what was the result of Liraglutide (1.8 mg) plus glimepiride on HOMA-B?

multiple_choice

The proportion of subjects experiencing minor hypoglycaemia during the trial was lowest with placebo (i.e. glimepiride monotherapy 2.6%; 0.17 events/subject-year), comparable with liraglutide 0.6 mg (5.2%, 0.17 events/subject-year) and rosiglitazone (4.3%, 0.12 events/subject-year) groups and similar between the liraglutide 1.2 mg (9.2%, 0.51 events/subject-year) and liraglutide 1.8 mg (8.1%, 0.47 events/subject-year) treatment groups. Incidence was higher with liraglutide 1.2 mg (P = 0.0024) and 1.8 mg (P = 0.0065) compared with rosiglitazone and liraglutide 1.2 mg compared with placebo (P = 0.048), occurring in the setting of lower mean HbA1c values.

109

199

3187863

Compared to Normal unit & Special unit what was the result of Midwife-led unit on Neonatal outcomes were evaluated by Apgar score <7 at 5 minutes, metabolic acidosis and transfer to NICU within 2 hours of birth?

multiple_choice

Of all women randomised to the MU, 15.8% had an epidural, which is a significantly lower rate than 23.3% in the NU (RR 1.47, 95% CI 1.11–1.96) and 24.8% in the SU (RR 1.57, 95% CI 1.16–2.13).

110

119

2871176

Compared to Placebo plus glimepiride what was the result of Liraglutide (1.2 mg) plus glimepiride on ADA fasting plasma glucose goals between 5.0 mmol/l and less than 7.2 mmol/l?

multiple_choice

The proportion of subjects experiencing minor hypoglycaemia during the trial was lowest with placebo (i.e. glimepiride monotherapy 2.6%; 0.17 events/subject-year), comparable with liraglutide 0.6 mg (5.2%, 0.17 events/subject-year) and rosiglitazone (4.3%, 0.12 events/subject-year) groups and similar between the liraglutide 1.2 mg (9.2%, 0.51 events/subject-year) and liraglutide 1.8 mg (8.1%, 0.47 events/subject-year) treatment groups. Incidence was higher with liraglutide 1.2 mg (P = 0.0024) and 1.8 mg (P = 0.0065) compared with rosiglitazone and liraglutide 1.2 mg compared with placebo (P = 0.048), occurring in the setting of lower mean HbA1c values.

111

400

2690844

Compared to Midline incision what was the result of Transverse incision on Complications after surgery?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

112

472

2847809

Compared to Placebo what was the result of Clopidogrel on Complications and mortality?

multiple_choice

The primary AVF failures at two months were 21.6% in placebo group and 5.2% in clopidogrel group (P = 0.03).

113

344

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Time to first COPD exacerbation?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

114

474

2847809

Compared to Placebo what was the result of Clopidogrel on The primary arteriovenous fistula failures at two months?

multiple_choice

The primary AVF failures at two months were 21.6% in placebo group and 5.2% in clopidogrel group (P = 0.03).

115

315

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on 1-hour post-dose FEV1 improvements?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

116

480

2447617

Compared to placebo what was the result of progesterone on The analysis using the dichotomization of GOS scores at 6 months post injury?

multiple_choice

The percentage of favorable outcome was 58% for the patients who were given progesterone and was 42% in the placebo group (P = 0.048). Forty-one percent of patients who were given progesterone and 57% of the placebo group exhibited an unfavorable outcome (P = 0.048).

117

324

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Mean FEV1 at 12 hours at end of treatment?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

118

406

2690844

Compared to Midline incision what was the result of Transverse incision on Scar width?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

119

481

2899760

Compared to anterior cervical decompression and fusion (ACDF) with Trabecular MetalTM (TM) what was the result of raditional Smith–Robinson (SR) procedure with autograft on Fusion rate?

multiple_choice

usion rate in the SR group was 92%, and in the TM group 69% (P < 0.05).

120

224

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Minnesota living with heart failure (MLHF) questionnaire baseline scores?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

121

374

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on Sleep score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

122

319

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Peak expiratory flow in the morning and evening ?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

123

440

2600646

Compared to dihydroartemisinin-piperaquine (AP) what was the result of arthemeter-lumefantrine (AL) on mean Hb?

multiple_choice

Final mean Hb levels were 7.15 mmol/l ± 1.07 for the DP treatment group and 6.79 mmol/l ± 1.24 for the AL group. A possible influence of anaemia on gametocyte carriage at enrollment was not observed in the present study (p > 0.05).

124

268

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Need for opiates?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

125

241

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Higher-order aberrations during the study?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

126

216

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Heart failure-related quality of life at the end of treatment?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

127

326

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Baseline-adjusted average 12-hour FEV1 at end of treatment?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

128

443

1468428

Compared to no enema what was the result of 1 litre saline enema on Puerperal and neonatal infection rates ?

multiple_choice

We found no significant differences in puerperal or neonatal infection rates (Puerperal infection: 41/190 [22%] with enema v 26/182 [14%] without enema; RR 0.66 CI 95%: 0.43 to 1.03; neonatal infection 38/191 [20%] with enema v 40/179 [22%] without enema; RR 1.12, 95% CI 95% 0.76 to 1.66)

129

341

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on 1-hour post-dose inspiratory capacity mean improvements from baseline to the average over the randomized treatment period?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

130

403

2690844

Compared to Midline incision what was the result of Transverse incision on Infection of the surgical site?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

131

347

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Amount of exacerbations per patient-treatment year?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

132

231

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Uncorrected distance visual acuity at 1 month?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

133

389

2690844

Compared to Midline incision what was the result of Transverse incision on Smaller incision ?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

134

482

2899760

Compared to anterior cervical decompression and fusion (ACDF) with Trabecular MetalTM (TM) what was the result of raditional Smith–Robinson (SR) procedure with autograft on clinical outcomes?

multiple_choice

usion rate in the SR group was 92%, and in the TM group 69% (P < 0.05).

135

367

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Overall use of daily rescue medication improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

136

402

2690844

Compared to Midline incision what was the result of Transverse incision on Urinary retention?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

137

283

2361806

Compared to Etoposide with 5-fluorouracil plus leucovorin (ELF) what was the result of Irinotecan with high-dose 5-fluorouracil plus leucovorin (ILF) on Overall survival?

multiple_choice

For ILF and ELF, respectively, median progression-free survival was 4.5 vs 2.3 months, time to treatment failure was 3.6 vs 2.2 months (P=0.4542), and overall survival was 10.8 vs 8.3 months (P=0.2818).

138

397

2690844

Compared to Midline incision what was the result of Transverse incision on Procedure performed directly by the staff surgeon?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

139

233

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Corrected distance visual acuity at 6 months?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

140

254

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Patients infected with T. vaginalis?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

141

282

2361806

Compared to Etoposide with 5-fluorouracil plus leucovorin (ELF) what was the result of Irinotecan with high-dose 5-fluorouracil plus leucovorin (ILF) on Time to treatment failure?

multiple_choice

For ILF and ELF, respectively, median progression-free survival was 4.5 vs 2.3 months, time to treatment failure was 3.6 vs 2.2 months (P=0.4542), and overall survival was 10.8 vs 8.3 months (P=0.2818).

142

385

2721929

Compared to Bladder training only (BT) what was the result of Bladder training plus tolterodine (Co) on Urgency score improvement?

multiple_choice

Mean urgency score decreased by 44.8%, 62.2% and 60.2% in the BT, To, and Co groups, respectively, and the improvement was significantly greater in the To and Co groups than in the BT group (p<0.05 for each).

143

467

3387601

Compared to intravenous immunoglobulin (IVIG) what was the result of plasma exchange (PE) on negative correlation between CSF protein and duration of mechanical ventilation?

multiple_choice

Examining the treatment groups separately, the significant negative correlation remained for the PE group (p-value = 0.037) and not for the IVIG group (p-value 0.132)

144

273

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Time to nasogastric decompression?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

145

456

3446002

Compared to control group what was the result of single dose of 50 mg/kg clofibrate on side effects?

multiple_choice

On serial daily examination during phototherapy and up to 2 days after that no problems or side effects were observed. Also for a period of two months no complication was detected.

146

269

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Hospital permanence?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

147

463

1876597

Compared to artemether-lumefantrine what was the result of dihydroartemisinin-piperaquine on Adverse Events?

multiple_choice

Overall, there was no difference in the proportion of study participants who experienced any adverse event of moderate or greater severity between the DP (46%) and AL (42%) treatment groups (p = 0.47).

148

238

3090298

Compared to Pre-surgery baseline what was the result of Photo-refractive keratectomy (PRK) on Contrast sensitivity at 3 months seen at 3 cpd?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

149

265

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Visual analog scale pain score at day 3?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

150

395

2690844

Compared to Midline incision what was the result of Transverse incision on Average patient's weight?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

151

264

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Visual analog scale pain score at day 1?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

152

370

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Cough score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

153

479

2447617

Compared to placebo what was the result of progesterone on The analysis using the dichotomization of GOS scores at 3 months post injury?

multiple_choice

The percentage of favorable outcome was 58% for the patients who were given progesterone and was 42% in the placebo group (P = 0.048). Forty-one percent of patients who were given progesterone and 57% of the placebo group exhibited an unfavorable outcome (P = 0.048).

154

261

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Programme meeting attendance?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

155

387

2721929

Compared to Tolterodine only (To) what was the result of Bladder training plus tolterodine (Co) on Urgency score improvement?

multiple_choice

Mean urgency score decreased by 44.8%, 62.2% and 60.2% in the BT, To, and Co groups, respectively, and the improvement was significantly greater in the To and Co groups than in the BT group (p<0.05 for each).

156

237

3090298

Compared to Pre-surgery baseline what was the result of Photo-refractive keratectomy (PRK) on Contrast sensitivity at 1 month seen at 3 cpd?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

157

423

1187893

Compared to No exercise what was the result of Exercise on Knee injury and Osteoarthritis Outcome Score quality of life subscale at 6 months?

multiple_choice

In the exercise group, an improvement was seen at 6 weeks in the KOOS subscale quality of life compared to the control group (mean change 4.0 vs. -0.7, p = 0.05). The difference between groups was still persistent at 6 months (p = 0.02).

158

323

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Mean FEV1 at 12 hours on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

159

316

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on 1-hour post-dose FEV1 improvements?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

160

217

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline hypertension?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

161

258

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Intake of STI treatment?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

162

441

2600646

Compared to dihydroartemisinin-piperaquine (AP) what was the result of arthemeter-lumefantrine (AL) on Adverse events?

multiple_choice

Final mean Hb levels were 7.15 mmol/l ± 1.07 for the DP treatment group and 6.79 mmol/l ± 1.24 for the AL group. A possible influence of anaemia on gametocyte carriage at enrollment was not observed in the present study (p > 0.05).

163

377

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on 24-hour urinary cortisol at 6 months?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

164

218

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline diabetes?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

165

255

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Secondary school education?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

166

393

2690844

Compared to Midline incision what was the result of Transverse incision on Pain on day three after surgery?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

167

473

2847809

Compared to Placebo what was the result of Clopidogrel on First hemodialysis success?

multiple_choice

The primary AVF failures at two months were 21.6% in placebo group and 5.2% in clopidogrel group (P = 0.03).

168

228

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline life-quality score?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

169

401

2690844

Compared to Midline incision what was the result of Transverse incision on Cardiac complications?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

170

310

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Time to discontinuation?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

171

355

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 160/9 μg on Breathlessness Cough and Sputum Scale improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

172

427

1187893

Compared to No exercise what was the result of Exercise on Functional performance improvement?

multiple_choice

In the exercise group, an improvement was seen at 6 weeks in the KOOS subscale quality of life compared to the control group (mean change 4.0 vs. -0.7, p = 0.05). The difference between groups was still persistent at 6 months (p = 0.02).

173

391

2690844

Compared to Midline incision what was the result of Transverse incision on Pain on day one after surgery?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

174

384

2721929

Compared to Bladder training only (BT) what was the result of Tolterodine only (To) on Urgency score improvement?

multiple_choice

Mean urgency score decreased by 44.8%, 62.2% and 60.2% in the BT, To, and Co groups, respectively, and the improvement was significantly greater in the To and Co groups than in the BT group (p<0.05 for each).

175

259

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Self-reported STI symptoms?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

176

407

2690844

Compared to Midline incision what was the result of Transverse incision on Better cosmetic appearance of the incision as subjectively assessed by patients?

multiple_choice

Postoperative complications (Table 4) were seen in 16 out of 75 patients (21%) from the midline incision group and in 15% from the transverse incision group (11 patients) (P = 0.30).

177

226

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Knowledge about heart failure?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

178

368

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Dyspnoea score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

179

257

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Genital discharge history?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

180

220

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Baseline beta-blockers intake?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

181

369

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 320/9 μg on Breathlessness Cough and Sputum Scale improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

182

250

2922723

Compared to Usual airway clearance techniques what was the result of High frequency chest wall oscillation on Visual analogue scale scores for efficacy?

multiple_choice

Patients scored the efficacy of their usual ACT significantly higher than for HFCWO (mean difference 14 mm; p=0.002).

183

450

2720945

Compared to placebo what was the result of cineole on Side effects?

multiple_choice

The difference between the two treatment groups was neither clinically relevant nor statistically significant. Safety examinations of the global assessment showed no difference between the two treatment groups.

184

232

3090298

Compared to Thin-flap laser in situ keratomileusis (LASIK) what was the result of Photo-refractive keratectomy (PRK) on Corrected distance visual acuity at 1 month?

multiple_choice

There were no significant differences between groups in any HOAs throughout the study (P ≥ 0.101), with all P values at 6 months ≥0.63.

185

227

1475568

Compared to Standard information about self-care what was the result of Follow-up and thorough education on self-care on Self-efficacy?

multiple_choice

The control group did have statistically significantly higher baseline MLHF scores representing worse symptoms at baseline.

186

477

2447617

Compared to placebo what was the result of progesterone on The mean intracranial pressure values 72 hours and 7 days after injury?

multiple_choice

The percentage of favorable outcome was 58% for the patients who were given progesterone and was 42% in the placebo group (P = 0.048). Forty-one percent of patients who were given progesterone and 57% of the placebo group exhibited an unfavorable outcome (P = 0.048).

187

281

2361806

Compared to Etoposide with 5-fluorouracil plus leucovorin (ELF) what was the result of Irinotecan with high-dose 5-fluorouracil plus leucovorin (ILF) on Overall response rates?

multiple_choice

For ILF and ELF, respectively, median progression-free survival was 4.5 vs 2.3 months, time to treatment failure was 3.6 vs 2.2 months (P=0.4542), and overall survival was 10.8 vs 8.3 months (P=0.2818).

188

266

2691927

Compared to Conventional open approach what was the result of Laparoscopic surgery on Visual analog scale pain score at day 7?

multiple_choice

Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure.

189

380

3580134

Compared to Formoterol DPI 9 μg what was the result of Budesonide/formoterol pMDI 160/9 μg on Incidence of pneumonia?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

190

256

1831737

Compared to Baseline communities that received standard Government services what was the result of Baseline communities that received additional education and preventive measures on Spatial mobility?

multiple_choice

T. vaginalis infection, secondary school education, and spatial mobility were more common in the control communities, whilst history of genital discharge and uptake of STI treatment and VCT services offered in the survey were low overall but more frequent in the intervention communities (Table 1). However, the differences in each case were small and were unlikely to be clinically meaningful.

191

285

2361806

Compared to Etoposide with 5-fluorouracil plus leucovorin (ELF) what was the result of Irinotecan with high-dose 5-fluorouracil plus leucovorin (ILF) on Grade 3/4 digestive system toxic events?

multiple_choice

For ILF and ELF, respectively, median progression-free survival was 4.5 vs 2.3 months, time to treatment failure was 3.6 vs 2.2 months (P=0.4542), and overall survival was 10.8 vs 8.3 months (P=0.2818).

192

361

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Dyspnoea score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

193

365

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Sleep score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

194

461

1876597

Compared to artemether-lumefantrine what was the result of dihydroartemisinin-piperaquine on unadjusted risk of recurrent falciparum parasitemia?

multiple_choice

Overall, there was no difference in the proportion of study participants who experienced any adverse event of moderate or greater severity between the DP (46%) and AL (42%) treatment groups (p = 0.47).

195

328

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Baseline-adjusted average 12-hour FEV1 on the day of randomization?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

196

386

2721929

Compared to Tolterodine only (To) what was the result of Bladder training plus tolterodine (Co) on Micturition frequency?

multiple_choice

Mean urgency score decreased by 44.8%, 62.2% and 60.2% in the BT, To, and Co groups, respectively, and the improvement was significantly greater in the To and Co groups than in the BT group (p<0.05 for each).

197

363

3580134

Compared to Placebo what was the result of Budesonide/formoterol pMDI 320/9 μg on Cough score improvement?

multiple_choice

Time to first COPD exacerbation was significantly prolonged with both budesonide/formoterol dosages compared with placebo (p ≤ 0.004) and with budesonide/formoterol 320/9 μg compared with formoterol (p = 0.026) [figure 6].

198

452

2720945

Compared to placebo what was the result of cineole on Mean of sum of number, duration and severity of exacerbations during 6 months of treatment?

multiple_choice

The difference between the two treatment groups was neither clinically relevant nor statistically significant. Safety examinations of the global assessment showed no difference between the two treatment groups.

199

455

3446002

Compared to control group what was the result of single dose of 50 mg/kg clofibrate on The duration of phototherapy?

multiple_choice

On serial daily examination during phototherapy and up to 2 days after that no problems or side effects were observed. Also for a period of two months no complication was detected.