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CLINICAL USE OF THE NEW BIOMARKER ST2 IN PATIENTS WITH CHRONIC HEART FAILURE OF ISCHEMIC GENESIS: AN EXERCISE TEST

Aim. To study the role of soluble stimulating growth factor expressed by gene 2 (sST2), at rest and after exercise at the end of six-minute walk distance (6MWD) in predicting the development of adverse cardiovascular events (CVA) in patients with coronary artery disease with chronic heart failure (CHF) for 12 months of prospective observation. Material and methods. We included 35 patients with CHF of ischemic genesis (32 men) with 44 left ventricular ejection fraction [35; 52]% (average age 62 [57; 67] years). The concentration of sST2 in serum was determined by enzyme immunoassay prior to and immediately after completion of 6MWD. Results. After 12 months of prospective observation, patients were divided into 2 groups depending on the CHF genesis. Group 1 (n=15) included patients with an unfavorable CHF course, group 2 (n=20) included patients without adverse CVA. In patients of group 1, the level of sST2 reached 39,68 [32,28; 52,32] ng/ml, which is 26,2% higher than (p=0,007) the similar parameter in patients of group 2 - 29,29 [26,34; 33,78] ng/ml. According to the ROC-analysis, the level of sST2 ≥33,14 ng/ml can be considered as a marker of the development of adverse CVA for 12 months of observations (sensitivity - 73,3%, specificity - 75,0%, area under the ROC curve - 0,77, p=0,002). After 6MWD patients with unfavorable CHF had a tendency (p=0,211) for an increase in sST2 level by 9,3% from 39,68 [32,28; 33,78] ng/ml to 43,75 [36,85; 54,80] ng/ml. In patients with a favorable course of CHF, the level of sST2 did not change, reaching 29,29 [26,34; 33,78] ng/ml and 29,43 [23,79; 34,79] ng/ml after 6MWD. According to the ROC-analysis, it was found that in patients with coronary artery disease and CHF, determining of sST2 concentration in the blood after 6MWD allowed to achieve higher levels of specificity and sensitivity of stratification risk method of adverse CVA - 86,7% and 85,0%, respectively (the area under the ROC curve is 0,86, p<0,0001). Conclusion. Thus, the level of sST2 can be considered as a noninvasive marker for predicting of unfavorable cardiovascular diseases in patients with CHF and intermediate/reduced left ventricular ejection fraction. Concentrations of sST2, determined after exercise, have a higher prognostic value for the stratification of the risk of an adverse course of CHF in this cohort of patients.

COMPLEX MINERAL MIXTURE BASED ON BELITE SLUDGE EFFECT ON THE FATTENING PIGS MEAT PRODUCTIVITY

The paper presents the results of studies on the effectiveness of feeding belite sludge and the created complex mineral mixture based on it in the feed of fattening pigs. A positive effect on the growth and safety of experimental animals, meat productivity, the quality of meat and lard has been established. The studies were carried out in the conditions of the economy of JSC "named after Chkalov" of the Ilanskiy District of the Krasnoyarsk Region and a zoological farm of the Institute of Applied Biotechnology and Veterinary Medicine of the Krasnoyarsk State Agrarian University on young pigs of a large white breed for two periods of fattening. To determine the effect of local mineral feeding on the meat qualities of fattening pigs, four groups of 10 heads each were formed, animals in the control group received 1% of the Borka mineral mixture to the basic diet (RR), the first experimental group - RR + 1 % of belite sludge , the second experimental group - OR + 1.5 % belite sludge, the third experimental group - OR + 1 % belite sludge in combination with iodine, manganese sulfate pentahydrate, copper sulfate pentahydrate, phosphoric fertilizing and zinc sulfate. At the end of the fattening period and the experiment, animals were slaughtered, 3 heads from each group, and the growth of muscle mass in the experimental groups was established when feeding various doses of belite sludge and a mineral mixture based on it. The inclusion of 1 % of a complex mineral mixture based on belite sludge in the diet of animals leads to an increase in the live weight of pigs by 5.85 %, the energy value of meat - 1.71 and, as a consequence, an increase in the profitability of production by 13.5 %.

SEAL OF LAUSAN-TAISHA

The monuments of Kalmyk sphragistics are diverse in their content. The legends on the stamps of Kalmyk rulers could be written down in Sanskrit, Chinese, Tibetan and Uigur languages. There were also monuments in Chinese language written with the square script. The purpose of the article is to introduce the sphragistic data on the Louzan-Taisha seal in Chinese language and to offer a hypothesis about its origin. The material was the publication of a letter of Louzan-Taisha to the Moscow tsar Mikhail Fedorovich. During the research the content of the legend on the seal was clarified, examples of similar seals in Tibet and China were given, and a hypothesis about the origin of the seal was put forward.

Evaluation of the development unevenness of the Russian Federation regions by socio-economic resource components

In the state strategy of the economic security of the Russian Federation the increased differentiation of regions and municipalities on the level and pace of socio-economic develop-ment is indicated as the main challenges, as well as the insufficient funding of industrial production, a weak innovation activity, lagging behind in the development and implementation of new and emerging technologies, increasing differentiation of the population by the income level, lack of labour resources, reduced quality and accessibility of education, health care and, as a result, the decline in the quality of the human capital.The purpose of this paper is to develop a system of integral indicators of resource components of socio-economic potential of the regions of the Russian Federation based on a legitimate, credible and accessible statistical data for the evaluation of their development unevenness. Materials and methods. Resource potential of the region is being considered as a collection of six groups of socio-economic indicators: fixed funds, financial and investment resource, labour resource, science and innovation resources, information resource and social resource. Each group includes indicators that are directly related to the possibilities of production of goods and services. In accordance with the methodological approaches of the resource capabilities evaluation of the region on the basis of integral indicators the principles of completeness, adequacy, accessibility, universality and formalization of the indicators are used. Evaluation of a group of indicators and all indicators of groups as a whole is made according to the values of integral indicators of reduction or exaggeration in comparison with the reference values of the resource components. Various indicators in the group have a different level of im-pact on the gross regional product that is taken into account in assessing their weight indicators. Time series values of the resource components in each group correlate with the time series values of the gross regional product, the coefficients values of pair correlation are used to recalculate them into weighting coefficients. Formulas for evaluating the individual indicators in the group are developed, integral indicators of the group of resource components and integral indicators of the resource potential of the region as a whole.Results. Given the significant differentiation of regions of Russia according to various objective factors, it is considered appropriate to compare regions within Federal Districts. For the Central Federal District, the Moscow region is taken as the benchmark for comparison, and relative levels of reduction in the resource components of other regions are calculated relative to the level of indicators of its resource potential. Analysis of the data shows that the highest level of resource reduction components of the Ivanovo region is observed in the resource group of science and innovation - 77.1 %, resources of the fixed funds, financial-investment and labour resources are equal the value of this indicator - from 42.3% to 45.4 %. The integrated indicator of relative resource reduction components in the Ivanovo area totaled 41.9 %.Conclusion. Using statistical data for the Ivanovo and Yaroslavl regions as examples, calculations of integral indicators are carried out, which demonstrate the possibility of assessing the regional development unevenness by their resource component of socio-economic development.

Work of the All-Russian Extraordinary Commission for Combating Counter-Revolution, Speculation, and Sabotage in northern provinces of the Soviet Russia in the economical sphere

The article is devoted to the role of the VChK bodies in realization of Communist party's economic policy. The author covers topics related to participation of chekists in realization of measures on abolition of private trade, realization of food dictatorship, struggle against smuggling, gamble, corruption, labour desertion. Changes in activity of the Soviet special services are shown at the period of transition to the new economic policy.

In-hospital outcomes and complications of percutaneous coronary interventions in STEMI in different age groups

Aim. To evaluate in-hospital outcomes of percutaneous coronary intervention for STEMI patients in different age groups. Materials and methods. 356 patients with STEMI who underwent PCI were enrolled in the study. According to the age, all patients were divided into 2 groups: "young" - at the age under 70 years; "non-young" - all patients at the age of 71 and over. In-hospital outcomes and clinical characteristics were analyzed. Results. In comparison with "young" group, patients over 71 years old demonstrate more high level of in-hospital mortality and hemorrhagic complications. "Non-young" patients present more severe condition, having myocardial and renal dysfunction, more likely to have recent hypertension and myocardial infarction. They are less likely to be tobacco smokers or have dyslipidemia. Conclusion. With increasing of age the patient’s condition in STEMI worsens: there is high level of in-hospital mortality. Despite of it, application of invasive reperfusion in STEMI shouldn’t be limited according to patient’s age. Primary PCI for them seems to be an effective and safe method of care in STEMI. The way to decrease the number of hemorragical complications in this group of patients requires next evaluation.

Analysis of international experience in institutional support of social tourism

Improving the organizational and institutional foundations of social tourism is one of the most important tasks of the socio-economic development of Russia, since, having a wide range of positive socio-economic consequences, social tourism affects a number of macroeconomic indicators, and also contributes to an increase in the level of social well-being of society. However, the formation of an effective organizational and economic mechanism for the support of social tourism services seems impossible without a deep study ofthe features ofthe institutional support of social tourism in a number offoreign countries, where the models of social tourism used for decades have already proven their effectiveness in solving socio-economic problems in market conditions at the national and transnational levels. Using a set oftheoretical and empirical research methods, the article classifies social tourism models that differ in funding sources, the mechanism ofinteraction between participants, and the degree of a financial burden on the state. The paper presents a comparative characteristic of these models with examples of their application in different countries. The analysis ofthe efficiency ofthe applied organizational and economic mechanisms for the support of social tourism services is carried out, their advantages and disadvantages are shown. Each of the models of social tourism is aimed at solving specific problems and is not universal, due to the uniqueness of management objects.

THE AGE DYNAMICS OF BIOCHEMICAL BLOOD INDICES IN BROILER CHICKEN (<i>Gallus gallus </i>L.)

Biochemical blood indices are important characteristics of physiological and health status of agricultural animals and poultry. In the past decades, the advanced measuring methodology and equipment including the development of automatic biochemical analyzers with standardized reagent kits have led to the significantly faster procedures and higher accuracy of analysis. The reference values of the biochemical indices determined by classic methods should therefore be redefined. In this study we report for the first time the revised reference values of biochemical blood indices including circulatory activity of blood digestive enzymes in growing broiler chicks ( Gallus gallus L.) during early ontogenesis (1 to 35 days of age). In the study, the hybrid chicks of an experimental broiler cross Smena 8 (line B59) were compared to their parental lines (Cornish line B5 and Plymouth Rock line B9) selected at the Smena Center for Genetic Selection (60 birds per genotype).The hybrids were fed ad libitum; parental lines were restricted in feed since day 15 of age. Mortality and live bodyweight were determined at 1, 7, 14, 21, 28, and 35 days of age. Two replicates of 10 birds per genotype were randomly taken for biochemical blood analyses. Blood was sampled from the jugular vein of decapitated chicks. Biochemical blood indices were measured by a flow semi-automatic biochemical analyzer Sinnowa BS3000P (Sinnowa Medical Science & Technology Co., Ltd., China) using reagent kits DIACON-VET (Russia). At 1 day of age in all studied genotypes concentrations of total protein, triglycerides, and calcium in blood serum were lower while concentrations of total phosphorus and total cholesterol were higher as compared to all subsequent ages. The most substantial increase in biochemical blood indices occurred during the first 7 days of age. This was due, among other factors, to the intensive growth of the body and the functional formation of the digestive system for this age period. The total protein concentration in blood serum increased with age in all genotypes because of proceeded body growth and the enhanced ability of protein synthesis. Concentration of total cholesterol tended to decrease with age, especially after 21 days of age. Concentration of triglycerides in serum increased to 14 days of age by 41.6-57.1 % as compared to the previous ages. There were no significant differences between the genotypes in total blood protein until 35 days of age. The hybrid chicks and their parental lines differed in the blood concentration of calcium, total phosphorus, and total cholesterol at 14 and 28 days of age, and triglycerides at 7 days of age. The blood digestive enzyme activities per live bodyweight decreased from day 1 to day 35 of age, most notably for trypsin (501-fold in hybrids, 453-fold in the Cornish line, and 442-fold in the Plymouth Rock line). Blood amylase activity decreased 100-, 52-, 50-fold, and lipase activity decreased 31-fold, 33-fold, and 35-fold, respectively.

SOME PROBLEMS OF FORMATION OF CREATIVE POTENTIAL OF TEACHERS

In this article formation problems of development of creative potential of teachers during preparation and carrying out the competition of professional skill are considered.

Using lattice theory for information processing in detection systems

We consider the problem of security systems development for land areas and strategic facilities. The results of lattice theory are used to justify the system structure and the approach to its design. We employ closure operator-based lattices to process and analyze data from sensors.

Belarusian State University students' marriage and family attitudes

The article analyzes the results of sociological research conducted by the method of questionnaire in 2016. The author examines the attitude of students of the Belarusian state university to the official registration of marriage and cohabitation; the opinion of the students' youth on the most favorable age for marriage, and important for them qualities of a life partner. Special attention is paid to the views of young people about models of family relationships (distribution of responsibilities between spouses, the combination of family and career, making important family decisions). The article is devoted to the reproductive attitudes of students. The author shows the students' attitude towards parenthood (presence of knowledge about conscious parenthood, the most interesting issues related to parenthood, preferred models of parenting).

INNOVATIVE ACTIVITY OF YOUNG ENTREPRENEURS AS A COMPETITIVENESS FACTOR OF INNOVATION START UPS IN RUSSIA (ON MATERIALS OF KAZAN STATE TECHNOLOGICAL UNIVERSITY)

Innovation by young entrepreneurs - it is a social need to develop not only our country, but also of any modern society of XXI century. Only through the active youth innovation can overcome the constantly evolving social conflicts between the growing human needs and limited resources to meet them. This article analyzes the activities of the state policy in order to support the Youth Innovation Entrepreneurship.

RANENBURG THEOLOGICAL SCHOOL OF THE 1890s ACCORDING TO THE MEMOIRS OF PROFESSOR NIKOLAI ALEXANDROVICH RYBNIKOV

The material is the first commented publication of a chapter of autobiographical research, done by an outstanding psychologist, professor of Moscow University N.A. Rybnikov. A native of the Ranenburg, district of Ryazan province, he received his primary education at Ranenburg Theological School. The chapter «Adolescence» gives a vivid description of the teaching staff of the school, analyzes the educational process and reveals its features, shows the life and customs of students. The published chapter contains a rich local history material that allows us to clarify certain aspects of the history of spiritual education on Ranenburg land.

Approaches to the definition of professional stability

The professional stability is closely linked with the processes of formation of professional and personal adaptation and socialization. Despite the considerable attention to the study of occupational stability, its definition and nature, structure and functions remain controversial. The general concept of stability for a man, unlike the case of material systems, is closely connected to such fundamental property as the activity. In this context, sustainability is a human dialectical synthesis of constancy and variability, conservation and development.

CRIMINAL PROHIBITIONS IN THE SPHERE OF THE MEDICAL PROFESSION: THE REALITY AND PERSPECTIVES OF LEGAL REGULATION

The article is devoted to the actual problems of establishing a criminal ban in the sphere of professional medical activity. The proposals of the Investigative Committee of the Russian Federation on amendments to the current criminal Code of the Russian Federation, on the basis of a sociological survey and the study of criminal cases, conclusions about the need for reform of the criminal law. The main conclusion is that it is impossible to solve urgent problems in Russian health care exclusively by criminal law means.

ELEMENTS OF THE ISLAMIC ECONOMY AS A TOOL FOR SOLVING SOCIAL INEQUALITIES IN SOCIETY

In this article is given an idea of the Islamic economy and its foundations, and examines in detail its elements such as zeket, sadaqah and waqf, as tools to reduce the social inequality of a country where a certain proportion of the population is Muslims.

Analysis of tactical actions of volleyball players of student teams of a non-core university

Outdoor games are one of the important components of the overall development of students of non-profile universities. Improving the methods of teaching volleyball with the help of outdoor games will allow the practicing coach to significantly increase both the physical and tactical readiness of young volleyball players. The chosen tactics include all kinds of actions that volleyball players take in various situations during competitive activities. Increasing the level of tactical preparedness will make it more expedient to use volleyball techniques, and, as a result, there will be more rational tactical pattern of the game. Therefore, naturally, the search for reserves for improving the tactical actions of young volleyball players is of particular importance.

Political Puns in A.I. Ghertzen's Publicistics

The study analyses Herzen's polical puns in his articles devoted to the exposure of autocracy in Russia. These works have a special language pattern and are structured according to the historic motivation of concrete situations in Russian political life during the 50s-60s of the XIX century. The problem of pun formation is topical. This issue has been the subject of specialized research works many times. Besides the well-known forms of wordplay, the author analyses rare expression, which are characteristic for Herzen's style. The stylistic types of puns formed in Herzen's articles show his skills and the values of his language culture.

YOUTH ENTREPRENEURSHIP AS A MEANS OF SOLVING THE PROBLEM OF UNEMPLOYMENT AMONG YOUNG PEOPLE

The article is devoted to the study of solving the problem of youth unemployment using entrepreneurship. The article reflects: changes in the social structure of Russian society, the problem of unemployment in general and among young people; disclosed youth unemployment as a chronic disease of the economy, its dynamics, factors aggravating it; problems of youth employment, as well as the pros and cons of youth as an active part of the population; considered entrepreneurship and its types as a means of solving the problem of youth unemployment; shows the attractiveness of entrepreneurship and its spheres for young people; the opportunities and ways of enhancing the entrepreneurial activity of young people are identified.

VIBRATION MECHANISMS SELF-BALANCING

Mechanisms, working bodies of which perform linear oscillations with a frequency high for their mass, which leads to the development of significant non-productive mechanical reactive inertial power, are considered in the article. Neutralization of the inertial power leads to a significant increase in the energy efficiency of the mechanism. The aim of the work is to determine conditions for automatic balancing of mechanisms with a constant reduced moment of inertia with four and three working bodies. It is established that the minimum number of working bodies performing linear oscillations in a balanced mechanism with a constant reduced moment of inertia is three.

THE DEVELOPMENT OF THE "VIABILITY" CONCEPT IN RUSSIAN AND FOREIGN PSYCHOLOGICAL RESEARCh

The article focuses on the notion of viability and compares how the concept is defined in russian and foreign research sources. Russian academics tend to consider an “ability” as an individual feature, and do not rely on it when addressing the “viability” issue. Western psychology primarily focuses on an individual’s social activity. Therefore, russian psychological science defines “viability” primarily as a psychological resource of an individual. Foreign psychological research, on the contrary, considers “viability” to be, on the one hand, an individual’s ability to construct the model of one’s lifestyle in accordance with their knowledge, skills, and abilities, and on the other, to be one’s resources which an individual could use to fulfil this lifestyle concept.

THE ROLE OF LOCAL GOVERNMENT IN CRIME PREVENTION (BY THE EXAMPLE OF AUSTRALIA)

The article describes the international experience of local authorities in the procedure for the prevention and prevention of crimes. Particular attention is paid to the activities of community groups, community involvement and a number of initiatives aimed at creating social cohesion, as well as attempts to overcome the disadvantaged situation in the area, especially in indigenous communities, whose activities seem necessary not only to prevent and suppress crimes and offenses their prevention.

Formulas in a problem of the search of the symbol of an linear operator

In the paper we propose some formulas for a solving a problem of search of the symbol of the operator by transition a solution of evolution equation from one temporal state to the another one.

NEO-NAZI AND EXTREMIST IDEAS AS A SOCIAL MENACE IN MODERN SOCIETY

Article analyzes such concepts as fascism and neo-fascism. Attention is focused on the current situation in the world, where there is a revival of fascism, which was suppressed by the USSR during the Second World War. This problem is relevant in our time, due to the aggravation of the political situation both in the near and far abroad. To combat fascism in our country, it is necessary to engage in Patriotic education of new generation. At the same time, leaving the national idea of love for the Motherland and parents.

Higher Pedagogical Education and Commercialization of Scientific Knowledge: Problems and Contradictions

The purpose of this paper is to determine the place and role of higher teacher education, teacher of high school in the context of commercialization of knowledge and modern social and economic transformations that are currently changing the psychology of people, society, shifting the individual and collective consciousness and spiritual and moral values toward commercialization relations. Analyzing the work of many scientists, using an interdisciplinary approach, it was found that the influence of the liberal transformation in the educational sphere, in particular pedagogical universities in the scientific literature is not enough. As a result, studies have highlighted the problem of spiritual and moral plan, which cuts across all spheres of modern society; the role of the teacher of higher teaching school as a repeater of scientific knowledge, ideology and values in the context of the paradigm of the gift or giving gifts was revealed; defines the mission of pedagogical universities – the formation of teachers, responsible, systematic in their thinking and knowledge, not only in the certain knowledge, but also capable of conveying correctly and scientifically verified to those of the younger generation system of socio-economic changes that accompany the social environment, promote the scientific outlook with accentuation on the moral and spiritual intelligence, which in a certain way denies the commercialization and commodification of thought and values; a sociological survey of students was conducted with a goal to, firstly, understand their vision of value constructs the carriers of which must be high school teachers, and, secondly, their relation to the commercialization of higher education. The prospect of further research should be to find answers to fundamental economic questions – what to produce?, how to produce? for whom to produce?, e. i. determining precise contours of the financial presence of the state in the production and provision of educational services by pedagogical universities.

AGE CHARACTERISTICS OF PEDIATRIC ROTAVIRAL INFECTION

Clinical laboratory research of rotaviral infections among 559 pediatric in-patients aged from 1 to 15 demonstrated predominance of medium severity episodes. In patients aged from 7 to 15, reduced duration of the main symptoms was notable. The biochemical data and ultrasonic test results indicated signs of pancreatic lesions in young children.

Role legal framework in the social dynamics of a modern civil society

The article considers the main factors of social dynamics of civil society, defined conditions, ensure its progressive development, identifies the factors that impede its positive dynamics, defines the role of legal frameworks in the social dynamics of civil society.

EFFECTS OF NITROGEN-FIXING AND PHOSPHATE-SOLUBILIZING MICROORGANISMS FROM THE FAR EAST AGRICULTURAL SOILS ON THE CEREAL SEED GERMINATION

Mineral fertilizers which can significantly increase crop productivity have an adverse effect on the soil and the environment as a whole when used for a long time. Microorganisms, as an alternative to mineral fertilizers, stimulate plant growth and development due to their ability to fix nitrogen, produce siderophores, phytohormones and enzymes, dissolve inaccessible elements of mineral nutrition, suppress plant pathogens, and increase consumption of water and nutrients. However, the effectiveness of such preparations highly depends on factors of a new environment. We believe that bacteria from soils that have long been exposed to various agricultural practices may be good plant stimulants. In the presented study, for the first time, we have isolated local active strains of nitrogen-fixing and phosphate-mobilizing bacteria from soils subjected to 74-year stationary intensive farming in the conditions of the Russian Far East and revealed isolates and their combinations which stimulate wheat and barley seed germination and seedling growth. The aim of the work was to study the plant-stimulating properties of nitrogen-fixing and phosphate-mobilizing bacteria from soils that have been actively exposed to mineral fertilizers for a long time. Bacteria were isolated from soils sampled in October 2015 (the experimental field 8, Federal Research Center for Agrobiotechnology FEB RAS, Ussuriysk, Primorsky Territory, Russia). The seeds of wheat Triticum aestivum L. cultivar Primorskaya 50, and barley Hordeum vurlage L. cultivar Tikhookeanskii (collection of the Federal Research Center for Agrobiotechnology FEB RAS) were treated. Of 68 bacterial isolates with different cultural and morphological properties, three isolates, the Acinetobacter spp. N1, Azotobacter spp. N2, and Clostridium spp. N3 were nitrogen fixers, and four isolates, the Serratia spp. P6, Bacillus spp. P7), Arthrobacter spp. P8, and Pantoea spp. P19 were phosphate-mobilizing bacteria. Tests with the monocultures of nitrogen-fixing and phosphate-mobilizing isolates and their different binary compositions showed a 13-51 % increase (p ≤ 0.05) in wheat seed germination energy and 15-54 % increase (p ≤ 0.05) in barley seed germination energy compared to the untreated control. Laboratory germination of wheat seeds increased by 2-32 %, barley seeds by 7-30 % compared to untreated control. The barley seedlings were 1.8 times longer, and the roots were 2.7 times longer. Th binary combination N2P19, P6P19, and P8P19 caused the highest height of seedlings (120-140 mm, p ≤ 0.05), and with P6P7, N2P19, and P6P19 the roots were the longest (120-130 mm, p ≤ 0.05). These results allow us to conclude that short-term soaking seeds in the suspensions of the tested nitrogen-fixing and phosphate-mobilizing isolates improves seed germination energy and laboratory germination, and increases shoot and root length. Binary bacterial compositions have a greater effect on seed germination than monocultures. The strains N1 ( Acinetobacter spp.), N2 ( Azotobacter spp.), and P19 ( Pantoea spp.) are the best stimulants. Species-specific differences in plant response to the treatment is probably due to lack of genetic, biochemical and physiological complementarities between specific plant species and the bacteria.

RISK-DIAGNOSTICS AND ASSESSMENT OF RISK FACTORS ON THE EXAMPLE OF THE CARGO TRANSPORTATION

The risk diagnostics and assessment of risk factors on the example of a cargo transportation of the Business Lines company is given in article. The structure of Russian Railway holding is presented.

ACTUAL FEATURES OF THE CONCLUSION OF STATE CONTRACTS

The study is aimed at public relations arising during the conclusion of public contracts. The subject of the study is the conclusion of a state contract. In the article, the author analyses some features of the conclusion of public contracts, such as the impressive amount of budgetary funds with many problems of legal application. In the article, the author explores scientific works on this issue. In addition, the author analyses elements of the system of the conclusion of state contracts of terminology and general nature, classification, procedural, status, formal, mandatory, security, and other content. The methodological basis of the study was the dialectical method of knowledge of social and legal phenomena, as well as frequent scientific methods: analysis of theoretical sources and regulatory and legal sources; comparison; generalization. Because of the study, the author comes to a number of conclusions that contribute to the understanding of the institution of the state contract.

DYNAMICS OF AMATEUR ARTS DEVELOPMENT IN THE MARI ASSR FROM THE BEGINNING OF THE XX CENTURY TILL 1941

The article reveals the processes of the development of amateur arts in the Mari ASSR from the beginning of the XX century till the Great Patriotic War in the all-Russian and all-Union context. The author analyzes the reasons for the gradual and stable growth of popularity and demand for amateur talent groups in the mentioned period, problems relating to their organization and functioning, investigates the role of “nonprofessional” associations in the development of the Mari Republic culture.

Perception and Representation of the Moscow Periphery: A Case Study of Yasenevo

The peripheral districts of Moscow are ambiguously perceived by residents in terms of communication with the city center. The residential identification of their district in the city as a center-peripheral system is distorted under the inftuence of the features of the local context. Using the example of Yasenevo district, this article answers the following questions: what are the differences between the representation of the district by its residents and the conditionally objective characteristics of its socio-economic situation? What are the possible reasons for these differences?The research paper provides a better understanding of a number of significant differences in the socio-economic characteristics of Yasenevo’s location on the edge of the city and their perception. Considerably the most significant reasons for these differences are the historical context of the area’s development and the existing subjective perceptions of residents about Yasenevo as a young and green district, which are only partially confirmed by statistics. Because of its location and partial isolation, the district is not perceived by residents as an urban periphery in the context of city-wide central-peripheral relations, but represents a similar system itself due to its unique planning structure.

The application of the LS-SVM method for the analysis of LIDAR and Motorcycle samples

In paper considers the application of the support vector machines with a quadratic loss function (LS-SVM) for solving practical problems. The analysis of known samples LIDAR and Motorcycle is considered. A brief description of the samples used, as well as the construction of LS-SVM normal, robust and sparse regression are given. For obtain a robust LS-SVM regression was used the methods pseudo-observation and weighing. For obtain a sparse LS-SVM regression, different sampling splitting approaches have been used. Such as: sample partitioning by D-optimal experiment planning and various sample partitioning algorithms based on criterion of model selection. The algorithms for the partitioning of the sample based on the criterion of model selection include algorithms: replacements, rejections, points inclusions, Add/Del, Del/Add, and virtual support vectors. Otherwise, these algorithms can be called the algorithm of additional optimization of the composition of points. To verify the efficiency of the algorithms the computational experiment was conducted. An improvement of the obtained results accuracy with LS-SVM method was achieved by selecting the scale of the Gaussian kernel function. The parameters of the kernel function was selected by the value of criteria for assessing model quality. A fixed value of 10 is used as a regularization parameter. The final solution accuracy was tested by the value of determination criteria. In the table form are shown the results of the determination criterion for each method of obtaining the regression model. The results of the LS-SVM regressions are shown graphical form. These results showed that the use of the LS-SVM method is quite acceptable for solving applied problems.

Legal Regulation for Children Support in Social Services Organizations in Modern Russia

The article analyzes regulatory documents and the mechanisms of organizing assistance to children social services organizations. The authors discuss the effectiveness of legislation in the field of social services. There is a large number of documents regulating the provision of social assistance to minors, their analysis should take into account the needs of children.

Efficacy and safety evaluation of branched-chain amino acids’ infusion form it the liver cirrhosis

Aim of the study: branched-chain amino acids’ (BCAA) efficacy and safety evaluation in intravenous infusion form (registered drug «Hepavil») at the post-marketing application for liver cirrhosis (LC) treatment. Materials and methods. Continuous sampling method applied for the cases at which Hepavil was used, with parallel continuous sampling of cases with chronic liver disease, in which other drugs were used, but no amino acids, followed by random sampling of the groups for analysis. Study protocol (program) was approved by the ethical committee. Data statistical processing was carried out using the software packages Statistica 6.1 (series 1203d), WinPepi, NCSS 2004. Results. There was a significant difference in the blood albumin levels in the liver cirrhosis group (LC) (N = 143): mean - 27.7 g/l (95% CI = 26.7-28.7), median - 28 (95% CI = 26-29 ) before treatment and an average of 35.1 g/l (95% CI = 34.1-36.1), median (Me) 36 (95% CI = 34-38) after treatment. OR increase in the proportion of patients with a blood albumin level of 35 g/l and more before / after the BCAA infusion therapy course is 8.28 at 95% CI = 4.44-15.42. The NNT was 2.2 (95% CI = 2.0-3.4). OR of the more frequent occurrence of blood albumin 35 g/l and higher after treatment with cirrhosis-B patients was 7.41 (95% CI = 2.9-18.7), with cirrhosis-C - 8.78 (95% CI = 3,1-24.9), with cirrhosis-C and ascites - 11.7 (95% D = 12.4-57.3), alcoholic cirrhosis-C - 14.4 (95% CI = 3.9-53.7 ), non-alcoholic cirrhosis-C - 6.67 (95% CI = 1.96-22.7). Hepavil treatment significantly reduced the patients’ incidence (in %) of a high prognostic per year mortality outcome index in patients with cirrhosis C: OR 4.5 (95% CI = 1.7-10.4) (for p = 0.012). There was a significant difference in blood platelet counts (secondary efficacy point): before treatment, mean was 146.4×109 (95% CI = 131.4-161.4), median (Me) - 123×109 (95% CI = 104-141 ) and after treatment mean was 169.4×109 (95% CI = 151.7-186.9), Me - 144×109 (95% CI = 122-165). The total incidence of mild adverse events (reactions) was 7.0% (95% CI = 3.4-12.5), the absolute risk of adverse events (reactions) was 0.07 and NNH - 13.7 (95% CI = 3,3-∞), while OR was statistically insignificant - 0.45 (95% CI = 0.1-1.7). There were no significant differences in OR of adverse events in the group of liver cirrhosis treated with BCAA in comparison with the group without treatment. Conclusion. BCAA infusions it liver cirrhosis demonstrated high efficacy on the blood albumin’s level. The NNT was 2.2 (95% CI = 2.0-3.4). Treatment with BCAA significantly reduced the patients’ with cirrhosis C incidence (in %) of a high prognostic per year mortality outcome index: OR is 4.5 (95% CI = 1.7-10.4) (for p = 0.012). Values of blood platelets before treatment were significantly lower than after treatment in patients with liver cirrhosis. The incidence of mild adverse events (reactions) according to clinical evaluation and laboratory-biochemical indicators was 7.0% (95% CI = 3.4-12.5) and NNH = 13.7 (95% CI = 3.3-∞). OR of adverse events’ development was not significantly different between LC treated groups, compared with the LC group without Hepavil treatment.

Dynamics of changes in biochemical parameters of blood of elderly people in the process of application of therapeutic and prophylactic products based on mare's milk

According to the study, it has been established that therapeutic and prophylactic products based on mare's milk have a beneficial effect on lipid metabolism and glucose metabolism, significantly reducing the risk of developing non-infectious diseases in the elderly. Their property has showed to slow the aging processes of bone tissue degradation, which reduces the risk of osteoporosis in elderly people.

FEATURES OF THE MARKET FOR ANTIHISTAMINES

The growth of allergic diseases is inevitable and is growing steadily. As technology changes, new components and ingredients are added, so in industrial cities there is an increase in the number of patients with allergies, because allergies are one of the diseases of peacetime and a kind of marker of the wellbeing of the country. Especially well exponential growth in the prevalence of allergic diseases is seen in countries with highly developed medicine and the absence of social disasters in the last 100 years. The article discusses the urgency of the growth of allergic diseases, presents statistical data on a global scale and across Kazakhstan, the classication of antihistamines, and the sales of major antihistamines in the Republic of Kazakhstan

DESIGN AND RESEARCH CULTURE AS A PEDAGOGICAL PHENOMENON

The article considers issues of formation and active construction of conceptually significant for future specialists in various areas of training design and research culture. Its phenomenological value for modern pedagogical science is investigated, and key problematic issues related to its implementation in the conditions of the educational process are determined. The elements of such a culture, their distinctive features and ways of influencing the professional activities of future specialists are considered. The author concludes that the formation of the design and research culture is inextricably linked with the formation of a directly professional culture, which is achieved during training in an educational institution, performing professional activities through planning, forecasting, designing certain objects. Professional activities should include design and research technologies, because without them it cannot be full-fledged and considered harmoniously developed, and such technologies, in turn, should focus on the development of the human professional sphere accordingly.

Gender peculiarities of primary schoolchildren's critical self-attitude determination

The article describes the investigation of critical self-attitude among primary schoolchildren and its determinants. Critical self-attitude is the attitude based on the divergence between the real self and the ideal self. This type of self-attitude is a new formation of primary school age. The data that we got showed that the development of critical self-attitude has a complex system of determination and is determined by the whole social development situation including school performance and the child's relations with the teacher, peers and parents. It was found that there are particular leading factors influencing the development of some self-attitude aspects. At the same time their influence is mediated by the other components of the social development situation. The investigation showed that gender differences of critical self-attitude determination can be found among primary school children.

Interlinguocultural Approach from the Position of Contact Variantology

Many scholars tend nowadays to agree with the statement that English language is diversified because of globalization and that it is represented by a number of varieties. In this connection, the problem of interactions between various languages and cultures is widely discussed today. This is reflected by the fact that there are a lot of newly introduced approaches in linguistics, for example, interlingaculturology and variantology. In order to compare these two approaches the author of this article tried to regard some of the processes that take place when these approaches are used and to give the explanation that is provided by these approaches to clarify the processes. Material for the research is majorly taken from the work by L.N. Tolstoy “War and Peace” in English translation. The result of the research showed that there is a contradiction between the two approaches. The author suggests a new communication model that allows to clearly see the point of contradiction. Moreover, there is a new understanding of what variety is presented in the article. Also, it is suggested by the author to look at the variantology approach from the position of synergetics, which is a rather unique twist is this discipline.

Principles of creating multimodal transportation and logistics centers

The work is devoted to the basics of the functioning of multimodal transport and logistics centers and the principles of creation. The goals of the establishment of the ITLC and their significance are given. The analysis of the basic types of MTLTs and the basic functions performed is performed. The need for construction and linkage to existing international transport corridors is justified. The increase of economic interests and their significance for the Central Asian republics and Kazakhstan is shown. The conducted researches show that the number of railway routes, oriented to the transit transport of Chinese goods, which do not represent significant competition and complement each other, is growing on the Eurasian continent. In addition, the tendency of the forecasted growth of the cargo flow is shown to 15-20% due to changing customer preferences from the sea route to the railway one. The main factor is the high speed of delivery - more than twice. Other reasons for this trend may be a technical process that increases the speed of communication and organizational and technical factors to increase competition through tariffs and fees, simplify customs procedures, etc. The most justifies the possibility of a significant increase in the role and economic opportunities of the ITLC in modern conditions.

Peculiarities of Chinese Numerals as an Independent Part of Speech

Focusing on Chinese numerals, the article considers the history of related research, analyzes existing definitions, provides argumentation for seeing Chinese numerals as a separate lexical and grammatical class of words, describes the grammatical features of these words (morphological as well as syntactical), and suggests a number of terminological solutions.

SOCIO-ECONOMIC EFFICIENCY OF QUALITY IMPROVEMENT ACTIVITY OF THE ENTERPRISES OF HOUSING AND COMMUNAL SERVICES

The article is devoted to the study of the issues of improving the quality of activity of enterprises of housing and communal services, carried out now in accordance with the state policy on modernization of housing and communal services of the Republic of Kazakhstan for 2011-2020. The study is aimed at determining the current mechanism of tariff formation for utilities and identifying recommendations to improve socio-economic efficiency. The article was made as part of the implementation of the scientific project AP05134552.

Traditions of Solidarity and Cooperation in the Space of Moscow Higher Women’s Courses

The article considers the issues of forming processes of interpersonal and public cooperation of domestic professors and students in the framework of their scientific-pedagogical and educational activities. The article focuses on the ideas of higher women’s education organization, its fundamentality and practical orientation on the example of Moscow Higher Women’s Courses, where a special spiritual microclimate was formed, which allows to speak about the formed scientific and educational organism as a united and integral one with inherent features of Russian collegiality, solidarity and cooperation.

Forming of cognitive interests in organization of primary school children's educational activity

The mechanisms of cognitive interests' forming in educational activity are considered in the article. The author proves relevance of educational activity arrangement on the basis of cooperation between a pupil and a teacher and pupil's active assistance and distinguishes the groups of cognitive interest incentives.

An improved formula for the universal estimation of digraph exponents

An early formula by A. L. Dulmage and N. S. Mendelsohn (1964) for the universal estimation of n-vertex primitive digraph exponent is based on a system C = {C₁,..., C_m} of directed circuits in the graph with lengths l₁,...,l_m respectively such that gcd(/₁,..., l_m) = 1. A new formula is based on a similar circuit system C with gcd(l₁,..., l_m) = d ^ 1. Also, the new formula uses the values г^((7) that are the lengths of the shortest paths from a vertex i to a vertex j going through the circuit system C and having the length comparable to s modulo d, s E {0,...,d - 1}. It's shown, that expT ^ 1 + F(L(C')) + R(C) where F(L) = d · F(l₁/d,...,l_m/d) and F(a₁,..., a_m) is the Frobenius number, R((7) = max max{г^((7)}. For a class of 2k-vertex (i,j) ^s primitive digraphs, it is proved that the improved formula gives the value of estimation 2k, but the early formula gives the value of estimation 3k - 2.

Speech Development of Urban and Rural Preschoolers

The article describes peculiarities of speech development of preschool-age children, living in urban and rural areas. The author compares language milestones of older preschoolers. The article overviews the mechanisms that determine differences in the speech of urban and rural children.

DYNAMICS OF VIBRATION FEEDERS WITH A NONLINEAR ELASTIC CHARACTERISTIC

Purpose. Subject to the smooth and efficient operation of each production line, is the use of vehicles transporting high specification. It worked well in practice for transporting construction machines, which are used during the vibration. The use of vibration machines requires optimization of their operation modes. In the form of elastic link in them are increasingly using rubber-metallic elements, which are characterized by nonlinear damping properties. So it is necessary to search for new, more modern, methods of calculation of dynamic characteristics of the vibration machines on the properties of rubber as a cushioning material. Methodology. The dynamics of vibration machine that is as elastic rubber block units and buffer shock absorbers limiting the amplitude of the vibrations of the working body. The method of determining amplitude-frequency characteristics of the vibrating feeder is based on the principle of Voltaire, who in the calculations of the damping properties of the dampers will allow for elastichereditary properties of rubber. When adjusting the basic dynamic stiffness of the elastic ties and vibratory buffers, using the principle of heredity rubber properties, determine the dependence of the amplitude of the working body of the machine vibrations. This method is called integro-operator using the fractional-exponential kernels of relaxation. Findings. Using the derived formula for determining the amplitude of the resonance curve is constructed one-mass nonlinear system. It is established that the use of the proposed method of calculation will provide a sufficiently complete description of the damping parameters of rubber-metallic elements and at the same time be an effective means of calculating the amplitude-frequency characteristics of nonlinear vibration systems. Originality. The authors improved method of determining damping characteristics of rubber-metallic elements and the amplitudefrequency characteristics of nonlinear oscillatory systems by introducing the calculation algorithm of dependency, taking account of elastic-hereditary properties of rubber. Practical value. The use of integro-operator method with the use of fractional-exponential kernels of relaxation, thereby increasing the accuracy of the calculations of the damping parameters of rubber goods and the amplitude-frequency characteristics of nonlinear oscillatory systems and provide an opportunity to further optimize operation modes of vibratory equipment. Made with regard to the principle of heredity properties of rubber, rubber-elastic suspension units for vibratory feeder exclude the probability limit line speed in the low durability of suspension parts feeder.

THE COHERENCE OF THE SUBJECT TRAINING OF BACHELORS OF PEDAGOGICAL EDUCATION FROM THE SCHOOL COURSE OF MATHEMATICS

In article on the basis of the analysis of the results of testing the new modules of educational programmes focus on the need to modernize substantive preparation of teachers of mathematics. Proposed structure of the subject training in disciplines closely associated with the school course. Selected disciplines are offered a list of topics, highlighting their links with the professional activities of the student. Discusses the basic substantial lines of subject training bachelor of pedagogical education by the profile Mathematics.

LEGAL REGULATION OF MIGRATION POLICY IN RUSSIA AND ABROAD

This article is devoted to the study of migration policy in the world. Considered the recent changes in the migration legislation of states, and their impact on the state of the migration situation. The methods of implementation in the adaptation and integration of foreign citizens are analyzed, as well as additional steps aimed at solving problems associated with foreign labor.

HASH INDEX APPROACH TO OPTIMIZE THE QUERY SEQUENCE Key

The article discusses a way to improve the efficiency of complex queries in modern DBMS. The method is based on the use of tree structures, key hash codes, and the possibility of optimization based on partitioning. As an additional aspect of optimization, the method of parallel operation of the proposed method is described.

FUTURE IN THE CREATIVE CONSCIOUSNESS OF YURI KUZNETSOV

The time system in the works of Yuri Kuznetsov involves biographical time, historical time and eternity of the other world, the biblical time in which the sacred history carries timeless spiritual and moral origin, mystery. The poet foretold his destiny of a great poet. The autobiographical time flows smoothly to the humanity time, predicting its future. The future of Russia is the most important part of the Russian idea – the fundamental idea in the works of Yuri Kuznetsov. The destiny of the national world is mysterious and changeable. Kuznetsov establishes two versions of the historical evoluiton – the prosperity of the Russian world and the recognition of its high spirituality by all of humanity, or the death of Russia and of all of humanity along with it. The poet associates the future with consolidation of the Orthodox faith.

Erythroderma: the modern questions of diagnostics and treatment

This article considers the modern approaches to terminology, classification, diagnosis, clinical manifestation and the treatment of the erythroderma. Authors touch upon questions about the meaning of the terminology “erythroderma”, with understanding pathogenesis, methods of making diagnosis and the treatment of the erythroderma.

PREVENTION OF FATIGUE IN STUDENTS USING AUDIOVISUAL STIMULATION

The purpose of the work is to study the effectiveness of the use of audiovisual stimulation for the prevention of fatigue in students. 111 students aged 19 to 21 years, studying at the Grodno state medical University, were tested to determine mental performance by the method of correction tables on the form of Bourdon-Anfimov before and after the session of audiovisual stimulation using modern mind-machine Photosonix Innerpulse (session R04 - waves of calm, at a frequency of 7,83-12 hz, tone type - double binaural beats). Control group - 25 people. The studies were conducted at the same time of the day (after the end of training sessions in the afternoon), in the same room. After the session of audiovisual stimulation, the speed of reaction, efficiency and concentration of attention of students significantly increased, which may serve as a basis for recommending the use of audiovisual stimulation using Photosonix Innerpulse to prevent fatigue and fatigue of students in the learning process and improve their performance.

The Physical and Technological Problems of Controlled Thermonuclear Fusion

The lines of scientific activity and the results of investigations carried out at the MPEI Department of General Physics and Nuclear Fusion are briefly reviewed. The conducted activities are mainly focused on the problems of controlled thermonuclear fusion and plasma technologies. Efforts are taken to study heat transfer and hydrodynamics in the plasma-facing structural components of thermonuclear reactors, one-sided heating of which results in essentially nonuniform distributions of heat flux density and wall temperature over the pipe inner perimeter. Another line of research activities is concerned with experimental investigations of nucleate boiling and heat transfer in essentially subcooled flow, of enhanced heat transfer in annular channels and models of pebble fuel element beds, and of heat transfer enhancement as applied to the problems concerned with cooling the International thermonuclear experimental reactor (ITER). A large-scale test bench for studying thermal-hydraulic processes in the models of advanced nuclear fuel assemblies operating with the parameters of a VVER-type reactor has been constructed. Activities are underway on studying the resistance of refractory metals to the effect of powerful plasma and heat fluxes expected to take place in a tokamak-type thermonuclear reactor. A plasma installation equipped with a linear multicusp magnetic system featuring uniquely high parameters has been constructed, which is used to perform tests of materials exposed to megawatt-scale hot plasma. The unique plasma installation has been constructed for studying plasma-to-surface interaction and high-temperature plasma testing of refractory materials like tungsten, molybdenum, steel, etc. The experiments to be performed on the installation are aimed at developing a new technology for producing a highly porous surface nanostructure of refractory metal, including tungsten “fuzz”. Such investigations are topical for inventing new materials that are of considerable interest for nuclear, chemical, power, and biomedical technologies. The main lines of activities on nanotechnologies include obtaining, studying and using carbon nanostructures such as fullerenes, carbon nanotubes, graphene, and their derivatives. Within the framework of studying the strengthening phenomenon, the extent of steel surface strengthening as a function of the type and intensity of incident radiation, and the type of nanocarbon material is considered. The interaction of charged particles and radiation with structural materials is investigated. Experimental and theoretical investigations of the interaction of electrons and light ions with inhomogeneous solid bodies are continued to solve the problems concerned with scattering ion beams in inhomogeneous media. Innovative methods for destructive and non-destructive analysis of thin films are developed, including layer-wise analysis techniques. Unique plasma installations have been constructed at the department, such as a high-frequency induction plasmatron for carrying out chemical spectral analysis, an arc plasmatron for studying the free plasma burning processes, a high-voltage installation for studying streamer and arc discharges with electrolysis, and a cold plasma installation for studying the effect of discharge on biological tissues. All these installations are successfully used for carrying out both research activities and student training laboratory works.

ANTARCTICA IS THE SOUTHERN GEOGRAPHICAL AREA OF THE EARTHAS A GEODYNAMIC CENTER OF FORMATION OF THE PRIMARY CRUST OF THE PLANET

It is shown that the continent of Antarctica, where the South Geographical Pole of the Earth is located, is the geodynamic center of formation of the primary crust of the planet. It is in the southern region of the planet, in accordance with the rules of the driller with respect to inertial forces, that the heavy mantle substance emission was directed, which formed the blocks-prisms of increased rigidity. Now they are located within the limits of oceanic depressions, marginal and inland seas and middle massifs of continents.

Detection of image areas for digital watermarking with usage of wavelet transformation

Modification of algorithm for embedding digital watermarks with using of wavelet transformation is considered. Integer wavelet transformation is used for detectors of contours and textures on image. Areas on the images with high detailing are determined by visual characteristics based on wavelet coefficients for data embedding.

Prevention of infectious and inflammatory complications after percutaneous nephrolithotripsy using the drug pyobacteriophage

Data on antimicrobial prophylaxis of infectious complications after percutaneous nephrolithotomy is presented in this article. The study was conducted among 60 patients with staghorn and multiple kidney stones who underwent percutaneous nephrolithotripsy (PCNL). For prevention of infectious complications of PCNL pyobacteriophage preparation or antibiotic drug were used. Nephrostomic tubes and urethral catheters were treated with pyobacteriophage preparation for 30 minutes to hinder the formation of bacterial biofilms. The study has shown that pyobacteriophage may be used for prevention and treatment of infectious complications of PCNL as an alternative to antibiotic prophylaxis, which is of great importance considering a rising prevalence of antibiotic-resistant strains. There was no difference in body temperature at 1, 3 and 7 days after the surgery, as well as in incidence of systemic inflammatory response between two groups. Moreover, 7 days after the surgery blood count parameters (white blood cells and banded neutrophils) were back to normal in all 4 groups, which leads to an assumption that antibiotics and bacteriophage preparations have equal efficacy. Constant monitoring of microbial sensitivity to bacteriophage preparations and regular selection of bacteriophages to pathogens of urological infection. Authors declare lack of the possible conflicts of interests.

FORENSIC MEDICAL EVALUATION OF SAWN SKIN DAMAGE

On the basis of experimental studies is established the complex of the morphological signs of the sawn wounds, whose manifestation depends on sharpness and construction of the teeth of the sawing instruments, and also on direction and multiplicity of saw-milling. The obtained data make it possible to facilitate essentially and to improve the quality of the conducted examinations.

ABOUT MUTUAL CONFORMITY OF THE FERROFLUDS BASIC PROPERTIES

The typical measurement results of magnetization, viscosity and density of a ferrofluid on the basis of polyethylsilicone (ПЭС-5) are presented. Mutual conformity of these properties is considered as a parameter of technology perfectness of ferrofluids preparation.

Accumulation of ¹³⁷Cs in spring wheat grain at different levels of nitrogen and potassium nutrition in anthropogenic-transformed peat soil

Anthropogenic-transformed peat soils occupy significant areas in the territory of the Republic of Belarus in composition of agricultural land contaminated with radionuclides. A number of studies have been carried out in recent years where diagnostic features, properties and fertility, regimes of mineral nutrition of plants on these soils have been studied. However, studies on radionuclides migration, impact of various agricultural practices on penetration into agricultural crops have not been carried out. The article dwells on study of ¹³⁷Cs penetration into spring wheat grain depending on the levels of nitrogen and potassium nutrition of plants when various rates of nitrogen and potassium fertilizers were applied on anthropogenic-transformed peat soil. It has been determined that N₁₂₀P₆₀K₁₂₀ application reduces ¹³⁷Cs level in grain by 15-22 % compared to the control, and when combined with mineral fertilizers, copper-containing fertilizer and plant growth regulator - by 34 %. The minimum accumulation of ¹³⁷Cs in spring wheat is determined at nitrogen-potassium ratio of 1 :(1.0-1.2). At the ratio of 1: (0.2-0.6) nitrogen deficiency and increase in radionuclide concentration in grain are observed due to yield decrease. Increase in accumulation of radionuclide in grain is observed at the ratio above 1:1.5. The results of researches make it possible to determine the allowable contamination density values of the anthropogenic-transformed peat soil with ¹³⁷Cs and optimal doses of mineral fertilizers for cultivation of food and forage purpose spring wheat.

Formation of fixed assets commercial organizations operating according to Sharia

Increasing religious identity of Russia’s population determines the relevance of research questions related with this circumstance. We investigate the issues of formation of own and leased fixed assets of a commercial organization, functioning on Sharia rules in the territory of the Russian Federation.

Control of Secondary Cooling in Dynamic Casting Modes

The aim of this paper is to study the influence of the secondary cooling control method on the temperature field of a continuous ingot under dynamic casting conditions. The main tasks were the development and implementation of a mathematical model of ingot cooling, as well as the identification of a control method that is used in a real industrial plant. As a research hypothesis, this paper considers the change in the surface temperature of a continuous ingot during the transition process. Significant temperature fluctuations negatively affect the condition of the metal, increasing its tendency to defects. Methods for evaluating methods for controlling secondary cooling are based on the results of mathematical modeling. The novelty of the research lies in the application of a new approach to mathematical modeling of changes in the thermal state of the metal under dynamic casting conditions, as well as a method for evaluating control methods based on temperature fluctuations along the entire length of the ingot during the transition process.

Multicultural education of technical institute student: the ways of improvement

The aspects of moulding multicultural education the technical institute student in multicultural region are considered in the article. One of the ways of research process organization is suggested. It is connected with subsequent realization of the following stages: from the acquaintance stage to the supporting stage and then to the self-overcoming one.

Use of complex vepol technologies in designing technological equipment for efficient processing of raw materials and production of food products

The results of the analysis of the efficiency of the use of traditional types of energy and the influence of physical and mechanical fields in the production, storage and transportation of food are presented. The complex effect of fields of different nature on technological processes is considered. New principles for the development and production of technological equipment based on the synergy of heat, ultrasound, vacuum, pressure, electromagnetic influences, mechanical vibration are proposed, which reduce the cooking time by 1,1-2,2 times, the number of mold fungi and mesophilic aerobic microorganisms by 1,5 and 2 times, respectively, and reduce energy costs by 10-15%. To assess the effect of the integrated use of various types of energy in the preparation and storage of food, the synergy coefficient is introduced and justified.

Dynamics of parameters in stochastic BMS models for oil and gas markets

The stochastic theory of asset portfolio management can be applied to build an optimal investment project for the development of oil and gas fields. Methods and quantitative estimates of adaptive BMS-models with stochastic switching are used, through which the minimum initial investment is found. The article presents graphs of the dynamics of the fundamental characteristics of BMS-models, which provide the construction of sufficiently accurate (with a normalized square deviation of no more than 9%) stochastic functions at each stability period, into which all spot daily price statistics from 1988 to the present can be divided. Graphs that show the nature and ranges of fluctuations in the parameters of BMS-models are provided, the statistical estimates of which for all stable periods were obtained from real trading data.

The Mechanism of Anti-Corruption Activities in the Economic Sphere of the State

Corruption groups with key figures in their ranks are analyzed. The economic preconditions of the corruption groups’ emergence are substantiated and their common and specific features are identified. The necessity of the formation of an organization-economic mechanism with government and public institutions involved in the fight against corruption on the basis of their partnership is shown. Methods to combat corruption taking into account various corruption schemes are defined.

Stimulating innovation activity and providing industrial-innovative development of the Republic of Kazakhstan

The article describes the institutional framework of national innovation system of the Republic of Kazakhstan. Also, the author presents an innovative infrastructure and defines the role of national and regional development institutions in promoting innovations, including the way through the operations of socio-entrepreneurial corporations, aimed at public-private partnership.

Tree injections - demand and supply

The paper reviews current market of injection treatment application services to protect trees against pests and diseases (in Russia). The companies that offer injections are analyzed according to their activities, specialization level, applied procedures and preparations. The state of the market oftree injection services in Russia clearly demonstrates that such services are in great demand. At the same time, this market is almost completely illegal, as currently there are no preparations allowed for injection. Such an abnormal situation cannot be maintained, since such a situation is capable, on the one hand, of significantly discrediting the very idea of tree injection. Tree injection can become an important part in the system of effective protection of plantprotection. Hence, favorable opportunities should be created for the registration of new modern preparations for the performance of such works. Lack of allowed preparations for application under the specified procedure in Russia, inconsistency of legal and regulatory background for injection applications to protect tree plants is stressed. A conclusion on need of operations to improve available situation and development of injection application conditions as an environmental procedure for preventive and control treatments of trees in forest areas, gardens and parks.

THE VALUE OF ECONOMIC ENTITIES IN THE LABOR MARKET

The author considers the problems of employment of population on the example of business entities that perform their duties in the field of air transport. Be aware that the sector in the North performs a huge role in employment.

Equine skin collagen is a new adjuvant

The investigation of the chemical and amino acid composition of alkaline-treated equine skin collagen and the physicochemical properties of its derived acetous solutions showed their identity with the much used solutions of alkaline-treated bovine skin collagen. The findings suggest that equine skin collagen may be used as an adjuvant and may replace bovine skin collagen in the technology of collagen preparations and medical products.

AUTOMATED COMPLEX FOR THE TRIBOLOGICAL PROPERTIES ANALYSIS’ OPERATION

The article describes the structure and principle of the automated complex for the tribological properties analysis’ operation, also the possibility of upgrading the complex has suggested.

Comparative analysis of morphological parameters of bone formation in bone augmentation using different types of membranes

The aim of this study was to conduct a comparative evaluation of two types of resorbable collagen membranes for guided bone regeneration. It compared the proliferative activity of allogeneic membrane made from dura mater and synthetic collagen membrane. The research was performed on biopsies of 30 patients who had undergone bone augmentation with the use of both types of collagen membrane. Morphological and histochemical studies of the biopsy samples showed a high proliferative activity and a moderate inflammatory response in the test samples.

The Russian Federation and transformation of concepts in the north of Europe

The author of the article examines the role of Russian Federation in cooperation and interaction with Nordic states in terms of transformation of geopolitical ideas, notions and concepts on European North.

THE DEPENDENCE OF FUNCTIONAL CHARACTERISTICS OF AN ORGANISM VISUALLY IMPAIRED STUDENTS FROM THE LEVEL OF PHYSICAL ACTIVITY

The article presents the results of the study of the dynamics of indicators of physical development, functional state of the cardiovascular system, psychophysiological indicators and the state of the Central nervous system in children with disabilities 9-10 years, determined their dependence on different levels of motor activity and adaptation of the body. The results obtained during the experiment reflect the nature of changes in somatometric and physiometric indicators, as well as the level of anxiety, indicating a positive effect of additional motor activity on the process of adaptation of the body of students. It is established that the response of CCC to the load in schoolchildren receiving additional physical activity is accompanied by a sufficiently effective implementation, which indicates a better degree of functioning of the cardiovascular system.

SEMANTIC STRUCTURE OF SELF-CONTROL WITH PSYCHOLOGICAL DEPENDENCE IN ADOLESCENCE

This article presents the results of the study of semantic personal psychological dependence of self-control in adolescence. Identify components of semantic self-control: Semantic focus, happiness, self-esteem, trust Installer samoprinât independence. Found significant differences in the structure of meaning of self-control of adolescent psychological dependence and psychological dependence.

IMPACT ASSESSMENT OF CELL CARDIOMYOPLASTY BY MESENCHYMAL SREM CELLS (MSCS) ON INDICES OF CARDIOMYOCYTES METABOLIC ACTIVITY IN EXPERIMENTAL MYOCARDIAL INFARCTION

The article is devoted to the solving of an actual scientific problem which is the justification of the effectiveness of isogenic cell cardiomyoplasty in myocardial infarction during the experiment. Experimental research was carried out on animals of Wistar-Kayota inbred. The total study included 42 animals (14 rats each, respectively), which formed 3 equal in the number of animals groups. In our studies, we have demonstrated the basic pathophysiological mechanisms of myocardial infarction in rats, such changes as decreasing of lactate dehydrogenase, erythrocyte adenosine desaminase and Creatine kinase-MB after using of common MSC’s. The myocardial infarction was caused by coronary artery ligation with subsequent application of various kinds of cardiomyoplasty. Further on, according to biochemical research, we studied the dynamics of markers of myocardial damage, lactate metabolism, lipid peroxidation. The common MSC’s proved effective in our experiment. Our data are consistent with the world literature that can be recommended to refrain the use of this type of cellular cardiomyoplasty in the future clinic research.

Clear sanitation felling as a method of control of the population density of stem pests and spreading of dendropathogenic organisms under the current conditions using Leningrad Region as a case study

The study presents the results of forest pathology monitoring and forest pest surveys, the reasons for appointments of sanitation felling, and forest pest and dendropathogen spread dynamics. A critical analysis of reasoning under sanitation felling orders and their results is given. It is concluded that the sanitation felling does not have significant affects on the density of pest populations and spreading of diseases on the territory of Leningrad Region. Strong winds are the main damaging factor in the region since 2010. According to the data of the Forest Protection Centre of Leningrad Region, the next by significance after hurricane winds reason for appointment of sanitation felling was forest diseases. Those diseases are mainly caused by Phellinus chrysoloma (Fr.) Donk, Heterobasidion annosum (Fr.) Bref., Phellinus tremulae (Bondartsev) Bondartsev & P.N. Borisov as well as spread of wound cancer and resin cancer. However, spreading of the pathogens increased after these fellings. Outbreak of European spruce bark beetle Ips typographus (L.) occurred in Leningrad Region in 2013-2015. The forest pathology inspection showed that in 2016 there was a sharp decrease of the Spruce bark beetle population density in the Sosnovsky and Zhitkowsky Forestries (north part of Karelian Isthmus) up to 500 and 1500 beetles of the parental generation per hectare, respectively. Heterobasidion annosum was absent in the surveyed area. Nevertheless, at the same location Ph. chrysoloma was registered sporadically and spruce wound cancer was wide spreading. In some areas, more than 50% of the trees had symptoms of the disease. Thus, the obtained data are in contradiction with the data of the Forest Protection Centre of Leningrad Region.

PRESENT PROSPECTS OF STURGEON AQUACULTURE

In the conditions of catastrophic decline in the number of natural populations of sturgeons in the Caspian basin, where more than 90% of the world's reserves are concentrated, sturgeon aquaculture is actively developing. The purpose of aquaculture is determined by two directions - artificial propagation for replenishing natural reserves and commercial sturgeon breeding to saturate world market with valuable products. The current status of these two directions of sturgeon aquaculture are considered, it is shown that for the successful development of sturgeon breeding it is necessary to form farmed broodstock under controlled conditions. It is proved that for the conservation of the biodiversity of natural populations, it is necessary to actively develop sturgeon aquaculture.

REGARDING THE COMPARABILITY OF THE INVESTIGATION OUTCOMES OF THE TRUE INTRAOCULAR PRESSURE ACCORDING TO THE PNEUTONOMETER REICHERT 7CR DATA AND APPLA- NATION TONOMETRY BY MAKLAKOV

The comparative investigation of 289 sound eyes and glaucomatous eyes with different level of intraocular pressure was performed. In all eyes the true IOPg was measured using the device manufactured by Reichert 7 cr and the applanation tonometry 10g by Maklakov using Nesterov-Egorov’s conversion lines was performed. The examination showed that in correct technology of print measuring the applanation tonometry results in IOPg up to 21 mm Hg coincided with the pneutonometry data in most cases. In higher levels of intraocular pressure IOPg was usually higher than in applanation tonometry.

FEATURES OF SUCCESS PERFORMANCE IN WOMEN IN RELATED RELATIONSHIP

The article is devoted to the topical problem of studying the characteristics of the ideas of success among women in codependent relationships. It highlights the theoretical foundations of the study of the characteristics of the ideas of success among women in codependent relationships, describes the methods used in the study, as well as the stages and results of empirical research. As a result of the conducted empirical research, it is proved that there are peculiarities of ideas among women in codependent relationships.

General monographs and pharmacopoeial monographs of the State pharmacopoeia of Russian Federation XIII edition

The State Pharmacopoeia of the Russian Federation is a collection of general monographs and pharmacopoeial monographs. It should be reissued at least once in 5 years. The next scheduled edition of the State Pharmacopoeia of the Russian Federation is planned for publication in 2015. It will include both first developed in national and, in some cases, global pharmacopoeial analysis general and pharmacopoeial monographs, and updated revised general and pharmacopoeial monographs. The implementation of the general and pharmacopoeial monographs of the mentioned edition of the State Pharmacopoeia of the Russian Federation will significantly increase the level of national pharmacopoeial analysis and ensure its compliance with international standards.

The problem of mismatch of supply and demand of engineering personnel in the local labor market. Experience in the study of partnerships between a regional university and enterprises

The article presents an analysis of the results of a study of the problem of relations between a regional technical university and partner enterprises employing graduates. The purpose of the study is to identify the reasons why there is a mismatch of supply and demand of engineering personnel in the local labor market. The allocation of «Chemistry» and «Fundamental and Applied Chemistry» as the main object of graduates of 2022 and an additional object of pharmaceutical cluster employers made it possible to see the difference in the views of both sides about the requirements for young specialists. The purpose of the survey of employers was to determine the current need for young specialists in the university’s profile direction. The purpose of the survey of graduates is to assess their intentions to work in their specialty and difficulties in finding employment. The importance of conducting such surveys as a feedback channel between the university and the enterprise is emphasized. Working in cooperation with enterprises, it is possible to adjust curricula in the direction of development.

AGROECOLOGICAL ASPECTS OF RECULTIVATION OF DISTURBED LANDS

The studies were conducted at the site of technogenic-disturbed agricultural lands located in the territory of the Verkhovsky district, the Orel region. Soil analysis was performed on the preselected samples in accordance with the applicable regulations in the field of soil analysis and methods of sampling GOST 26483-85. Preparation of salt extract and determination of its pH was done by the method of TIN, GOST 26951-86. Ionometric nitrate determination was performed by the method, GOST R 54650-2011. Determination of mobile potassium and phosphorus was done by the method of Kirsanov, RD 52.18.289-90 MU. We applied the technique of measurements of the mass fraction of metals mobile forms in soil samples by atomic absorption, GOST 26210-91. Determination of exchangeable potassium was performed by Maslova’s method, GOST 26213-91. We used methods of organic substance definition. The aim of this work is to establish the influence of unorganized landfills municipal solid waste (MSW) on the environment and agro-ecological indexes of soil. The effect of illegal dumping of MSW on the environment and agro-environmental indicators of fertile soil layer is determined. Agroecological studies of section of the fertile soil layer overlap with a total area of 16016.0 m²are carried out. The increase of high concentration of humus (organic matter), mobile forms of phosphorus, potassium and reduction of soil acidity in comparison with control are observed. Waste management on the site has led to a significant increase in the content of toxic chemical elements - salts TM. The excess of MPC was, on average, on cadmium by 1.23 times, on copper by 6.075 times, on zinc by 17.84 times, on manganese by 5.11, on lead by 1.59 times. To eliminate negative impacts of solid waste on the environment and soil fertility in the survey area the implementation of complex measures on reclamation of disturbed lands is recommended. Radical biological and physical chemical methods of detoxification are recommended.

ABILITIES AND LIMITATIONS OF INTEGRATION OF TWO EDUCATIONAL SUBSYSTEMS: WHO WINS?

Abilities and limitations of integration of secondary professional and supplementary education are analyzed in the article. Materials on organization of events directed on quality management in providing educational services for the youth by means of attracting resources of supplementary education are represented. Potential of network interaction of secondary professional and supplementary education in increasing professional and general cultural competences of educational organizations in seconodary professional education is described. The data of a sociological questionnaire of a value of processes of integration for students, their parents, and teaching staff are given.

MODEL OF INQUIRY SERVICE IN THE CONTEXT OF THE HISTORICAL EXPERIENCE

The article is devoted to the analysis the activity of the service of inquiry in Russian internal affairs bodies. It is proposed to model, taking into account historical experience and current reforms.

improvement of Pyrusl. pear classification and assessment of representatives of identified varieties in the conditions of the North Caucasus

A study in the field of classification of pears is one of the important scientific problems of modern Pomology. Creation of a natural classification of varieties, taking into account the commonality of many characteristics and qualities, is a relevant point. To improve existing developments in this area, the long-term results of varietal studies of pears in the collection stands of the Maykop Experimental Station VIR (MOS VIR) branch have been analyzed and the varieties of the collection have been grouped according to morphological characteristics and biological properties. Creation of an open system of pear varieties, which includes, along with the previously defined subspecies of common pear (South European, West European, East European, Transcaucasian, Central Asian), the East Asian subspecies that we have identified, is the result of the research. It combines the varieties of East Asia, including the Far East of Russia, and includes five varieties: Bailey, East Golden, Girinskaya, Olga, Shinsui. Mramornaya variety has been added, including new hybrid varieties of Eastern Europe, to the Eastern European subspecies. In each new variety type, the varieties most promising for selection and production have been identified. The creation of the proposed classification contributes to wider and fuller use of the extensive varietal gene pool of pears, both for practical purposes and for theoretical research.

Risk factors for the probable development of invasive candidiasis in the HIV-infected

Objective. To identify risk factors for and probability of developing of invasive candidiasis (IC) in patients with HIV infection. Subjects and methods. A case-control study was conducted in a specialized department of the Perm Regional Clinical Hospital for Infectious Diseases in 2012-2014. A case group included 43 patients with the confirmed diagnosis of IC; a control group consisted of 59 patients without IC. The groups were matched for sex, age, residence, stage of HIV infection, counts of CD lymphocytes, and the absence of antiretroviral therapy. Results. The HIV-infected patients with IC were significantly more frequently observed to have factors, such as oropharyngeal candidiasis and tuberculosis, intensive care unit stay, prior gastrointestinal surgery and mechanical ventilation, active psychoactive substance dependence, stay in prison places, and the lack of a permanent job. To predict the development of IC in the HIV-infected, it is advisable to use at least three of the nine identified signs, the totality of which is characterized by the highest sensitivity (88.3%) and specificity (98.3%). Conclusion. The identified factors can be used for the prediction of a risk for IC in HIV-infected patients, for timely examination, early diagnosis, and adequate therapy.

Ironic notes on the current situation in sociology

The article notes as an irreversible fact: the vocabulary and topics of modern sociology have become postmodern. This paradigm shift needs to be evaluated. It is known that the language of assessment should not coincide with the language of the criticized phenomenon. Therefore, the author chose the “ironic style” for his story. The main objects of “irony”: 1) the “universal” crumbled into fragments of the “local” - on the example of the concept of “pluralism of civilizations”; 2) “factocentrism”, when the very fact of the existence of things justifies their existence; 3) “Otherness” has supplanted the concept of “norms”. And so on. Conclusion: modern society needs an “ontology for society”, where ontology is understood as a model of authentic, true (but not arbitrary) existence of things.

Analysis of problems of pulling grooves of complex shape in Russia and abroad

This article analyses the status and problems of broaching blades of compressors in Russia and abroad. There is considered load experienced by the cutting insert during operation. Random selection of inserts of carbide products from the catalog of Kirovgrad Hard Alloy Plant for titanium and heat-resistant steels based on the forces acting on the cutting insert.

COMBINE AND ROW TECHNOLOGY OF VEGETABLE AND POTATO CULTIVATION IN SOIL OVERHUMIDATION AREA

The article considers the technology of cultivation of vegetables and potatoes on ridges and ridges. Ridges and ridges are an ancient agricultural technique used in vegetable and field growing. The history of vegetable growing potato growing and other crops in Russia is associated with the use of ridges and ridges. Comb method of growing crops has found wide application in China. When cutting ridges and ridges with plowing tools, the fertile soil layer is selected from the rows and concentrated under the rows of plants, which increases the active layer for the development of the root system of cultivated plants by 1.2 - 2 times. The positive influence of ridges and ridges on the chemical, water - physical and thermal properties of the soil has been proved experimentally and under production conditions.In the soil, microbiological activity improves, oxidative processes increase.

GENESIS OF THE THEORY OF EVIDENCE AND THE EVIDENTIARY PROCESS IN THE JUDICIAL PROCESS IN THE ANCIENT EAST (EXAMPLE OF ANCIENT INDIA AND ANCIENT CHINA)

Subject During the existence of proto-states formed the fundamental principles of judicial-procedural law: the general provisions of evidence, the theory of evidence and evidentiary process. On the basis of the ancient world law sources the process of transformation and expansion of evidence, changes in the process of proving during different periods of proto-states of the ancient East (on the example of ancient China and ancient India) was studied. Aims/Objectives A detailed description of the peculiarities of evidence and the process of proof in ancient China and ancient India has been reproduced on the basis of extant sources of ancient Oriental law. Before embarking on a study of modern law of evidence, it is necessary to know the process of establishment, application and subsequent development of the theory of evidence in law. Methodology The methods of comparative law, formal legal method, methods of chronology and periodisation as well as methods of synthesis and analysis were used. Conclusion The authors have formed a general idea about the theory of evidence and the process of proof: the theory of evidence of ancient China and ancient India is formal in its legal nature (in terms of giving legal effect to every proof in advance), and the process of proof during its entire genesis in the Ancient East preserved the stages of proof: collection (by the court or participants in the process), and their checking and evaluation entirely by the court. The primary formation of the foundations of the judicial process brought significant results for the specification in subsequent historical periods of the properties of evidence, as well as the order of their collection, evaluation and verification. The authors also point to procedures which are fundamentally similar to those of modern times for the examination of evidence, such as the features of the institute of Narada-smriti handwriting examination. The authors believe that the peculiarities of ancient oriental evidentiary law need to be studied in detail on an ongoing basis.

Possible Sources of Investment Funds in the Agricultural Sector of the Regional Economy

The author examined the sources of investment funds in the agricultural sector of the economy of the region, analyzed the possibility of greater and more effective investment in agriculture of the Republic of Adygea.

Kidney damage in HIV infection: pathogenetic aspects, clinical and morphological variants and the role of antiretroviral therapy

The review analyzes the prevalence and pathogenetic aspects of HIV infection. The main clinical and morphological variants of kidney damage in HIV infection are outlined. The prevalence of kidney damage in HIV infection is 20-30%, which are represented by such clinical and morphological variants as HIV-associated nephropathy (VAN), immunocomplex HIV-associated kidney disease, and thrombotic microangiopathy. In patients with HIV infection who are not treated with antiretroviral therapy (ART) the most common type of kidney disease is HIVAT. A decrease in the number of CD4+ cells, high viral load, advanced age, and the presence of kidney pathology in the next of kin are risk factors for the development of HIVAT. Specific risk factors for kidney damage in HIV infection are the use of antiretroviral drugs (tenofovir), the uncontrolled use of which is accompanied by tubular dysfunction. In HIV infection, the degree of immunodeficiency correlates with the severity of kidney damage. The most common histopathological manifestations of kidney damage in individuals with HIV infection are focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis, immunoglobulin A nephropathy, and mesangioproliferative glomerulonephritis. Hypertension, nephrotic syndrome, and reduced CD4+ cells are predictive of renal failure in HIV infection. In patients with HIV infection who are treated with ART the appearance of hypokalemia, nocturia, polyuria, microhematuria, and/or subnephrotic proteinuria is indicative of tubulointerstitial disease. To assess the total filtration function of the kidneys in people with HIV infection, the most acceptable formula is CKD-EPI.

The Fund of Scientific and Technical Preparation of Production Formation

The article examines the issue of funding the stage of scientific and technical preparation of production. Possible ways to accumulate funds for scientific and technical works are analyzed. The STPP fund formation is offered.

Spiritual Kinship and the Phenomenon of Trust in the Sociological Studies of Guido Alfani

This article provides an overview of the research on cross kinship carried out under the direction of the historian and sociologist Guido Alfani. The author examines the concept of god-parenthood as a phenomenon of the spiritual-social network that shaped the urban economy in Italy. Despite the fact that the institution of reception has its origins in the pre-Christian period, its baptism seriously altered both spiritual and social relations in historical Europe. One of the consequences of the spread of godparenting has been the expansion of social trust between professional and class groups. Such a spiritual-social institution makes it possible to build a system of trusting relationships that help maintain a stable bond between different social strata, and is essentially a mechanism of social integration conducive to the development of commerce. Guido Alfani looks at different historical periods: the formation of Christianity, the schism of the churches, the Western Church in the Middle Ages, the Reformation, the Council of Trent, the New Age. In each period he describes different types of cross kinship, which depended on various social factors: church reforms, revolutions, and changes in social norms.

Montreal Convention for International Carriage by Air as a Part of Legal System of Russia

In light of Russia's adherence to the Convention for the Unification of Certain Rules for International Carriage by Air adopted at Montreal on 28 May 1999 (“Montreal Convention”) and the integration of the Montreal Convention into the Russian legal system, this article provides a short but in-depth analysis of the Montreal Convention in comparison with the Warsaw Convention 1929 for the Unification of Certain Rules for International Carriage by Air and the Russian legislation. The author (a) provides the scientific and theoretical evaluation of the legal mechanisms created by the Montreal Convention in order to facilitate their correct use and application, (b) identifies the fundamentals and the advantages of the new set of rules for international carriage by air, and (c) nalyses the legal, socio-economic and political consequences of Russia's adherence to the Montreal Convention and the strategic goals of the Russian legislation and case law. A central part of the article is taken by such issues as the carrier's liability towards passengers for death and personal injury, cargo and baggage claims, late delivery, recovery of damages. The article also covers the issue of claims against the carrier, and the insurance of carrier's liability. The research is based on the methods that include dialectical, historical, logical, legal, comparative and technical analysis, functional, systematic and structural approach, analogy, synthesis and legal modeling. The article provides the conclusion that even though certain rules of the Russian legislation are in conflict with the Montreal Convention, the Montreal Convention would still be applicable in the Russian legal system based on Section 4 of Article 15 of the Russian Constitution, but such rules of the Russian legislation prejudice the interests of the state and its citizens and require further improvement.

ZERO RESET TECHNOLOGY FOR DRILLING SEA WELLS

The technology of the socalled zero discharge during offshore drilling is considered. The environmental vulnerability of offshore and the Arctic forces Russian scientists to carry out technologies related to industrial work in these conditions, taking into account the strategic assessment (SEA). The serious environmental risks associated with hydrocarbon production can be significantly reduced through the application of the best developed technologies and methods. Modern technologies allow minimizing environmental risks.

CHARACTERISTIC OF THE PREVALENCE OF CONGENITAL MALFORMATIONS AMONG CHILDREN IN ORENBURG REGION

The article presents data on the prevalence of congenital malformations among children in the Orenburg region over the past 15 years. It is established that congenital heart defects occupy the leading place in the structure of congenital malformations. Among the first identified congenital malformations, dominated by heart disease with the enrichment of the small circle of blood circulation, more often in boys living in rural areas. The obtained scientific data determine the need to develop a system of monitoring of congenital heart diseases, their early diagnosis and correction of the revealed pathology.

DEFINITION OF LIFE PART OF OIL AND GAS EQUIPMENT

There are considered questions of identify of the durability of details of oil and gas equipment. It is shown formulas for determining the number of loading cycles until cracking. As an example, the calculation of the base detail durability of hydraulic disconnector for flexible pipes of ID 60,3 mm.