SaProtHub/AVIDa-hIL6_Interaction_prediction

Base model: westlake-repl/SaProt_35M_AF2

Model Card for Model ID

AVIDa-hIL6 is an antigen-variable domain of heavy chain of heavy chain antibody (VHH) interaction dataset produced from an alpaca immunized with the human interleukin-6 (IL-6) protein. This model is used to predict interaction between AVIDa-hIL6 and IL-6 protein.

Task type

protein-protein pair classification

Dataset description

The dataset is from AVIDa-hIL6, which contains 573,891 antigen-VHH pairs with amino acid sequences.

Binary label represented by 1 for the binding pair and 0 for the non-binding pair.

Model input type

Amino acid sequence pair

Performance

test_acc: 0.99

LoRA config

lora_dropout: 0.0

lora_alpha: 16

target_modules: ["query", "key", "value", "intermediate.dense", "output.dense"]

modules_to_save: ["classifier"]

Training config

class: AdamW

betas: (0.9, 0.98)

weight_decay: 0.01

learning rate: 1e-4

epoch: 10

batch size: 280

precision: 16-mixed