diff --git "a/text/Active_site_ids.tsv" "b/text/Active_site_ids.tsv"
new file mode 100644--- /dev/null
+++ "b/text/Active_site_ids.tsv"
@@ -0,0 +1,10511 @@
+Catalysis involves the residue at position 140 playing the role of Proton acceptor.
+Catalysis involves the residue at position 216 playing the role of Proton acceptor.
+Catalysis involves the residue at position 180 playing the role of Proton acceptor.
+Catalysis involves the residue at position 396 playing the role of Nucleophile.
+Catalysis involves the residue at position 186 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 34 playing the role of Nucleophile.
+Catalysis involves the residue at position 214 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 192 playing the role of Proton acceptor.
+Catalysis involves the residue at position 126 playing the role of Proton donor.
+Catalysis involves the residue at position 98 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 366 playing the role of Proton donor.
+Catalysis involves the residue at position 397 playing the role of .
+Catalysis involves the residue at position 525 playing the role of .
+Catalysis involves the residue at position 308 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 59 playing the role of .
+Catalysis involves the residue at position 368 playing the role of Proton acceptor.
+Catalysis involves the residue at position 497 playing the role of Proton donor.
+Catalysis involves the residue at position 164 playing the role of Proton acceptor.
+Catalysis involves the residue at position 249 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 126 playing the role of .
+Catalysis involves the residue at position 145 playing the role of .
+Catalysis involves the residue at position 193 playing the role of .
+Catalysis involves the residue at position 196 playing the role of .
+Catalysis involves the residue at position 219 playing the role of .
+Catalysis involves the residue at position 228 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 645 playing the role of Proton acceptor.
+Catalysis involves the residue at position 204 playing the role of Proton donor.
+Catalysis involves the residue at position 185 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 224 playing the role of .
+Catalysis involves the residue at position 226 playing the role of .
+Catalysis involves the residue at position 231 playing the role of .
+Catalysis involves the residue at position 404 playing the role of .
+Catalysis involves the residue at position 406 playing the role of .
+Catalysis involves the residue at position 411 playing the role of .
+Catalysis involves the residue at position 88 playing the role of Proton donor.
+Catalysis involves the residue at position 8 playing the role of Proton acceptor.
+Catalysis involves the residue at position 131 playing the role of Proton donor.
+Catalysis involves the residue at position 131 playing the role of .
+Catalysis involves the residue at position 134 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 390 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 159 playing the role of Proton acceptor.
+Catalysis involves the residue at position 265 playing the role of Proton donor.
+Catalysis involves the residue at position 374 playing the role of Proton acceptor.
+Catalysis involves the residue at position 75 playing the role of Proton donor.
+Catalysis involves the residue at position 312 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 496 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 433 playing the role of Proton acceptor.
+Catalysis involves the residue at position 188 playing the role of Proton donor.
+Catalysis involves the residue at position 88 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 171 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 175 playing the role of Proton donor.
+Catalysis involves the residue at position 687 playing the role of Proton acceptor.
+Catalysis involves the residue at position 268 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 283 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 853 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1198 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1227 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 50 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 57 playing the role of Proton donor.
+Catalysis involves the residue at position 233 playing the role of Proton acceptor.
+Catalysis involves the residue at position 67 playing the role of Proton acceptor.
+Catalysis involves the residue at position 100 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 169 playing the role of .
+Catalysis involves the residue at position 261 playing the role of .
+Catalysis involves the residue at position 264 playing the role of .
+Catalysis involves the residue at position 287 playing the role of .
+Catalysis involves the residue at position 296 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 14 playing the role of .
+Catalysis involves the residue at position 167 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 36 playing the role of Proton acceptor.
+Catalysis involves the residue at position 47 playing the role of Proton acceptor.
+Catalysis involves the residue at position 131 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 154 playing the role of Proton donor.
+Catalysis involves the residue at position 82 playing the role of Proton donor.
+Catalysis involves the residue at position 186 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 316 playing the role of .
+Catalysis involves the residue at position 190 playing the role of Proton acceptor.
+Catalysis involves the residue at position 308 playing the role of Proton acceptor.
+Catalysis involves the residue at position 95 playing the role of Nucleophile.
+Catalysis involves the residue at position 108 playing the role of Nucleophile.
+Catalysis involves the residue at position 204 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 140 playing the role of .
+Catalysis involves the residue at position 545 playing the role of .
+Catalysis involves the residue at position 66 playing the role of Proton acceptor.
+Catalysis involves the residue at position 109 playing the role of Proton acceptor.
+Catalysis involves the residue at position 65 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 143 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 361 playing the role of Proton donor.
+Catalysis involves the residue at position 392 playing the role of .
+Catalysis involves the residue at position 517 playing the role of .
+Catalysis involves the residue at position 176 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 62 playing the role of Proton acceptor.
+Catalysis involves the residue at position 143 playing the role of .
+Catalysis involves the residue at position 82 playing the role of Nucleophile.
+Catalysis involves the residue at position 171 playing the role of .
+Catalysis involves the residue at position 66 playing the role of .
+Catalysis involves the residue at position 138 playing the role of .
+Catalysis involves the residue at position 17 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 232 playing the role of Proton acceptor.
+Catalysis involves the residue at position 154 playing the role of Proton acceptor.
+Catalysis involves the residue at position 328 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 37 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 267 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 153 playing the role of Proton acceptor.
+Catalysis involves the residue at position 137 playing the role of Nucleophile.
+Catalysis involves the residue at position 319 playing the role of Proton acceptor.
+Catalysis involves the residue at position 78 playing the role of Charge relay system.
+Catalysis involves the residue at position 158 playing the role of Charge relay system.
+Catalysis involves the residue at position 182 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 209 playing the role of Proton donor.
+Catalysis involves the residue at position 339 playing the role of Proton acceptor.
+Catalysis involves the residue at position 168 playing the role of Proton acceptor.
+Catalysis involves the residue at position 10 playing the role of Proton acceptor.
+Catalysis involves the residue at position 129 playing the role of Proton donor.
+Catalysis involves the residue at position 193 playing the role of Proton acceptor.
+Catalysis involves the residue at position 421 playing the role of Nucleophile.
+Catalysis involves the residue at position 149 playing the role of .
+Catalysis involves the residue at position 517 playing the role of Proton acceptor.
+Catalysis involves the residue at position 14 playing the role of Proton acceptor.
+Catalysis involves the residue at position 42 playing the role of Proton donor.
+Catalysis involves the residue at position 106 playing the role of Proton acceptor.
+Catalysis involves the residue at position 12 playing the role of Proton acceptor.
+Catalysis involves the residue at position 197 playing the role of Proton donor.
+Catalysis involves the residue at position 60 playing the role of .
+Catalysis involves the residue at position 147 playing the role of .
+Catalysis involves the residue at position 205 playing the role of Proton donor.
+Catalysis involves the residue at position 206 playing the role of Proton acceptor.
+Catalysis involves the residue at position 117 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 156 playing the role of Proton donor.
+Catalysis involves the residue at position 174 playing the role of .
+Catalysis involves the residue at position 250 playing the role of .
+Catalysis involves the residue at position 368 playing the role of Nucleophile.
+Catalysis involves the residue at position 7 playing the role of .
+Catalysis involves the residue at position 70 playing the role of .
+Catalysis involves the residue at position 160 playing the role of Nucleophile.
+Catalysis involves the residue at position 204 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 257 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 305 playing the role of Charge relay system.
+Catalysis involves the residue at position 54 playing the role of Nucleophile.
+Catalysis involves the residue at position 167 playing the role of Proton acceptor.
+Catalysis involves the residue at position 286 playing the role of Proton acceptor.
+Catalysis involves the residue at position 88 playing the role of Charge relay system.
+Catalysis involves the residue at position 173 playing the role of Charge relay system.
+Catalysis involves the residue at position 270 playing the role of Charge relay system.
+Catalysis involves the residue at position 179 playing the role of .
+Catalysis involves the residue at position 319 playing the role of .
+Catalysis involves the residue at position 123 playing the role of Proton acceptor.
+Catalysis involves the residue at position 86 playing the role of .
+Catalysis involves the residue at position 22 playing the role of Proton donor.
+Catalysis involves the residue at position 186 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 275 playing the role of Proton acceptor.
+Catalysis involves the residue at position 155 playing the role of Proton acceptor.
+Catalysis involves the residue at position 92 playing the role of Proton acceptor.
+Catalysis involves the residue at position 337 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 628 playing the role of .
+Catalysis involves the residue at position 125 playing the role of Proton donor.
+Catalysis involves the residue at position 17 playing the role of .
+Catalysis involves the residue at position 154 playing the role of .
+Catalysis involves the residue at position 78 playing the role of .
+Catalysis involves the residue at position 141 playing the role of .
+Catalysis involves the residue at position 165 playing the role of .
+Catalysis involves the residue at position 336 playing the role of Proton acceptor.
+Catalysis involves the residue at position 108 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 198 playing the role of Charge relay system.
+Catalysis involves the residue at position 228 playing the role of Charge relay system.
+Catalysis involves the residue at position 306 playing the role of Charge relay system.
+Catalysis involves the residue at position 29 playing the role of Nucleophile.
+Catalysis involves the residue at position 276 playing the role of Proton donor.
+Catalysis involves the residue at position 237 playing the role of Proton acceptor.
+Catalysis involves the residue at position 218 playing the role of Proton acceptor.
+Catalysis involves the residue at position 260 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 175 playing the role of Proton acceptor.
+Catalysis involves the residue at position 294 playing the role of Proton acceptor.
+Catalysis involves the residue at position 140 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 168 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 107 playing the role of .
+Catalysis involves the residue at position 79 playing the role of Proton donor.
+Catalysis involves the residue at position 210 playing the role of Proton donor.
+Catalysis involves the residue at position 351 playing the role of Proton acceptor.
+Catalysis involves the residue at position 89 playing the role of Proton acceptor.
+Catalysis involves the residue at position 271 playing the role of Nucleophile.
+Catalysis involves the residue at position 175 playing the role of Nucleophile.
+Catalysis involves the residue at position 116 playing the role of Proton donor.
+Catalysis involves the residue at position 105 playing the role of Proton acceptor.
+Catalysis involves the residue at position 13 playing the role of Proton acceptor.
+Catalysis involves the residue at position 41 playing the role of Proton donor.
+Catalysis involves the residue at position 79 playing the role of Nucleophile.
+Catalysis involves the residue at position 167 playing the role of .
+Catalysis involves the residue at position 95 playing the role of Charge relay system.
+Catalysis involves the residue at position 163 playing the role of Charge relay system.
+Catalysis involves the residue at position 190 playing the role of Charge relay system.
+Catalysis involves the residue at position 194 playing the role of .
+Catalysis involves the residue at position 86 playing the role of Nucleophile.
+Catalysis involves the residue at position 172 playing the role of .
+Catalysis involves the residue at position 72 playing the role of .
+Catalysis involves the residue at position 142 playing the role of .
+Catalysis involves the residue at position 183 playing the role of .
+Catalysis involves the residue at position 409 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 319 playing the role of Proton donor.
+Catalysis involves the residue at position 777 playing the role of Proton acceptor.
+Catalysis involves the residue at position 8 playing the role of Nucleophile.
+Catalysis involves the residue at position 48 playing the role of Nucleophile.
+Catalysis involves the residue at position 75 playing the role of Charge relay system.
+Catalysis involves the residue at position 150 playing the role of Charge relay system.
+Catalysis involves the residue at position 174 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 365 playing the role of Proton acceptor.
+Catalysis involves the residue at position 179 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 84 playing the role of Nucleophile.
+Catalysis involves the residue at position 78 playing the role of Nucleophile.
+Catalysis involves the residue at position 362 playing the role of Proton acceptor.
+Catalysis involves the residue at position 90 playing the role of Nucleophile.
+Catalysis involves the residue at position 216 playing the role of .
+Catalysis involves the residue at position 244 playing the role of .
+Catalysis involves the residue at position 357 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 164 playing the role of Proton donor.
+Catalysis involves the residue at position 210 playing the role of Nucleophile.
+Catalysis involves the residue at position 54 playing the role of .
+Catalysis involves the residue at position 329 playing the role of Proton acceptor.
+Catalysis involves the residue at position 2 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 3 playing the role of Proton donor.
+Catalysis involves the residue at position 58 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 253 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 117 playing the role of .
+Catalysis involves the residue at position 257 playing the role of .
+Catalysis involves the residue at position 187 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 317 playing the role of .
+Catalysis involves the residue at position 139 playing the role of Proton acceptor.
+Catalysis involves the residue at position 177 playing the role of Proton acceptor.
+Catalysis involves the residue at position 115 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 296 playing the role of Proton donor.
+Catalysis involves the residue at position 91 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 153 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 182 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 360 playing the role of Proton acceptor.
+Catalysis involves the residue at position 57 playing the role of Proton acceptor.
+Catalysis involves the residue at position 309 playing the role of Charge relay system.
+Catalysis involves the residue at position 91 playing the role of Proton acceptor.
+Catalysis involves the residue at position 340 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 155 playing the role of Charge relay system.
+Catalysis involves the residue at position 220 playing the role of Charge relay system.
+Catalysis involves the residue at position 315 playing the role of Charge relay system.
+Catalysis involves the residue at position 332 playing the role of Nucleophile.
+Catalysis involves the residue at position 91 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 343 playing the role of Proton acceptor.
+Catalysis involves the residue at position 373 playing the role of Proton acceptor.
+Catalysis involves the residue at position 198 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 50 playing the role of Nucleophile.
+Catalysis involves the residue at position 53 playing the role of Nucleophile.
+Catalysis involves the residue at position 170 playing the role of Nucleophile.
+Catalysis involves the residue at position 173 playing the role of Nucleophile.
+Catalysis involves the residue at position 385 playing the role of Proton acceptor.
+Catalysis involves the residue at position 106 playing the role of Proton donor.
+Catalysis involves the residue at position 106 playing the role of .
+Catalysis involves the residue at position 2 playing the role of Nucleophile.
+Catalysis involves the residue at position 61 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 279 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 182 playing the role of Proton donor.
+Catalysis involves the residue at position 198 playing the role of Proton acceptor.
+Catalysis involves the residue at position 202 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 161 playing the role of .
+Catalysis involves the residue at position 309 playing the role of .
+Catalysis involves the residue at position 383 playing the role of .
+Catalysis involves the residue at position 413 playing the role of .
+Catalysis involves the residue at position 11 playing the role of Proton acceptor.
+Catalysis involves the residue at position 196 playing the role of Proton donor.
+Catalysis involves the residue at position 315 playing the role of .
+Catalysis involves the residue at position 181 playing the role of Nucleophile.
+Catalysis involves the residue at position 37 playing the role of Nucleophile.
+Catalysis involves the residue at position 120 playing the role of Proton donor.
+Catalysis involves the residue at position 113 playing the role of .
+Catalysis involves the residue at position 319 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 99 playing the role of Proton acceptor.
+Catalysis involves the residue at position 57 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 259 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 166 playing the role of Proton acceptor.
+Catalysis involves the residue at position 110 playing the role of Proton donor.
+Catalysis involves the residue at position 199 playing the role of .
+Catalysis involves the residue at position 672 playing the role of .
+Catalysis involves the residue at position 131 playing the role of Proton acceptor.
+Catalysis involves the residue at position 92 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 382 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 332 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 169 playing the role of Nucleophile.
+Catalysis involves the residue at position 335 playing the role of .
+Catalysis involves the residue at position 368 playing the role of .
+Catalysis involves the residue at position 37 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 450 playing the role of .
+Catalysis involves the residue at position 266 playing the role of Nucleophile.
+Catalysis involves the residue at position 73 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 89 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 151 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 180 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 427 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 123 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 160 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 10 playing the role of Nucleophile.
+Catalysis involves the residue at position 185 playing the role of Proton donor.
+Catalysis involves the residue at position 285 playing the role of Proton acceptor.
+Catalysis involves the residue at position 516 playing the role of .
+Catalysis involves the residue at position 135 playing the role of Proton acceptor.
+Catalysis involves the residue at position 182 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 324 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 187 playing the role of Proton acceptor.
+Catalysis involves the residue at position 20 playing the role of Proton donor.
+Catalysis involves the residue at position 1139 playing the role of Nucleophile.
+Catalysis involves the residue at position 1264 playing the role of .
+Catalysis involves the residue at position 1266 playing the role of .
+Catalysis involves the residue at position 253 playing the role of Proton acceptor.
+Catalysis involves the residue at position 83 playing the role of .
+Catalysis involves the residue at position 275 playing the role of .
+Catalysis involves the residue at position 220 playing the role of .
+Catalysis involves the residue at position 152 playing the role of Proton acceptor.
+Catalysis involves the residue at position 67 playing the role of .
+Catalysis involves the residue at position 139 playing the role of .
+Catalysis involves the residue at position 257 playing the role of Proton acceptor.
+Catalysis involves the residue at position 283 playing the role of Proton acceptor.
+Catalysis involves the residue at position 78 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 18 playing the role of Proton acceptor.
+Catalysis involves the residue at position 164 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 129 playing the role of Proton acceptor.
+Catalysis involves the residue at position 68 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 122 playing the role of .
+Catalysis involves the residue at position 95 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 96 playing the role of Proton acceptor.
+Catalysis involves the residue at position 270 playing the role of Nucleophile.
+Catalysis involves the residue at position 163 playing the role of .
+Catalysis involves the residue at position 342 playing the role of Proton acceptor.
+Catalysis involves the residue at position 264 playing the role of Proton donor.
+Catalysis involves the residue at position 68 playing the role of .
+Catalysis involves the residue at position 43 playing the role of Nucleophile.
+Catalysis involves the residue at position 92 playing the role of Nucleophile.
+Catalysis involves the residue at position 83 playing the role of Proton donor.
+Catalysis involves the residue at position 114 playing the role of .
+Catalysis involves the residue at position 100 playing the role of Proton acceptor.
+Catalysis involves the residue at position 341 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 281 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 449 playing the role of Proton donor.
+Catalysis involves the residue at position 148 playing the role of Proton donors.
+Catalysis involves the residue at position 204 playing the role of Nucleophile.
+Catalysis involves the residue at position 119 playing the role of .
+Catalysis involves the residue at position 184 playing the role of Proton acceptor.
+Catalysis involves the residue at position 191 playing the role of Proton donor.
+Catalysis involves the residue at position 146 playing the role of Nucleophile.
+Catalysis involves the residue at position 74 playing the role of Proton donor.
+Catalysis involves the residue at position 209 playing the role of Proton acceptor.
+Catalysis involves the residue at position 160 playing the role of Proton acceptor.
+Catalysis involves the residue at position 47 playing the role of .
+Catalysis involves the residue at position 93 playing the role of Proton acceptor.
+Catalysis involves the residue at position 9 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 87 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 479 playing the role of Proton acceptor.
+Catalysis involves the residue at position 78 playing the role of Proton donor.
+Catalysis involves the residue at position 73 playing the role of .
+Catalysis involves the residue at position 132 playing the role of Proton acceptor.
+Catalysis involves the residue at position 102 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 129 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 105 playing the role of .
+Catalysis involves the residue at position 169 playing the role of Proton acceptor.
+Catalysis involves the residue at position 287 playing the role of Proton acceptor.
+Catalysis involves the residue at position 243 playing the role of .
+Catalysis involves the residue at position 277 playing the role of .
+Catalysis involves the residue at position 108 playing the role of Proton acceptor.
+Catalysis involves the residue at position 22 playing the role of Proton acceptor.
+Catalysis involves the residue at position 50 playing the role of Proton donor.
+Catalysis involves the residue at position 247 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 103 playing the role of Nucleophile.
+Catalysis involves the residue at position 200 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 321 playing the role of Nucleophile.
+Catalysis involves the residue at position 355 playing the role of Proton acceptor.
+Catalysis involves the residue at position 23 playing the role of Proton acceptor.
+Catalysis involves the residue at position 100 playing the role of Proton donor.
+Catalysis involves the residue at position 129 playing the role of .
+Catalysis involves the residue at position 123 playing the role of .
+Catalysis involves the residue at position 313 playing the role of Proton acceptor.
+Catalysis involves the residue at position 341 playing the role of Proton donor.
+Catalysis involves the residue at position 19 playing the role of .
+Catalysis involves the residue at position 144 playing the role of .
+Catalysis involves the residue at position 181 playing the role of Proton acceptor.
+Catalysis involves the residue at position 166 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 2 playing the role of .
+Catalysis involves the residue at position 575 playing the role of .
+Catalysis involves the residue at position 132 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 186 playing the role of .
+Catalysis involves the residue at position 188 playing the role of .
+Catalysis involves the residue at position 109 playing the role of Nucleophile.
+Catalysis involves the residue at position 442 playing the role of .
+Catalysis involves the residue at position 489 playing the role of .
+Catalysis involves the residue at position 498 playing the role of .
+Catalysis involves the residue at position 133 playing the role of Proton acceptor.
+Catalysis involves the residue at position 99 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 450 playing the role of For 3-hydroxyacyl-CoA dehydrogenase activity.
+Catalysis involves the residue at position 37 playing the role of .
+Catalysis involves the residue at position 152 playing the role of .
+Catalysis involves the residue at position 95 playing the role of Electrophile.
+Catalysis involves the residue at position 306 playing the role of .
+Catalysis involves the residue at position 127 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 96 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 160 playing the role of .
+Catalysis involves the residue at position 348 playing the role of Charge relay system.
+Catalysis involves the residue at position 468 playing the role of Charge relay system.
+Catalysis involves the residue at position 498 playing the role of Charge relay system.
+Catalysis involves the residue at position 243 playing the role of Proton donor.
+Catalysis involves the residue at position 116 playing the role of .
+Catalysis involves the residue at position 44 playing the role of Nucleophile.
+Catalysis involves the residue at position 211 playing the role of .
+Catalysis involves the residue at position 320 playing the role of Nucleophile.
+Catalysis involves the residue at position 405 playing the role of Nucleophile.
+Catalysis involves the residue at position 458 playing the role of Proton donor.
+Catalysis involves the residue at position 33 playing the role of .
+Catalysis involves the residue at position 102 playing the role of .
+Catalysis involves the residue at position 282 playing the role of .
+Catalysis involves the residue at position 356 playing the role of .
+Catalysis involves the residue at position 285 playing the role of .
+Catalysis involves the residue at position 305 playing the role of .
+Catalysis involves the residue at position 70 playing the role of Proton acceptor.
+Catalysis involves the residue at position 127 playing the role of .
+Catalysis involves the residue at position 206 playing the role of .
+Catalysis involves the residue at position 62 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 106 playing the role of Nucleophile.
+Catalysis involves the residue at position 108 playing the role of Proton donor.
+Catalysis involves the residue at position 156 playing the role of .
+Catalysis involves the residue at position 127 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 165 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 164 playing the role of .
+Catalysis involves the residue at position 191 playing the role of .
+Catalysis involves the residue at position 288 playing the role of .
+Catalysis involves the residue at position 49 playing the role of Proton acceptor.
+Catalysis involves the residue at position 60 playing the role of Proton acceptor.
+Catalysis involves the residue at position 117 playing the role of Proton donor.
+Catalysis involves the residue at position 45 playing the role of Proton acceptor.
+Catalysis involves the residue at position 72 playing the role of Proton acceptor.
+Catalysis involves the residue at position 193 playing the role of Proton donor.
+Catalysis involves the residue at position 183 playing the role of Proton acceptor.
+Catalysis involves the residue at position 858 playing the role of .
+Catalysis involves the residue at position 860 playing the role of .
+Catalysis involves the residue at position 865 playing the role of .
+Catalysis involves the residue at position 1254 playing the role of .
+Catalysis involves the residue at position 1256 playing the role of .
+Catalysis involves the residue at position 1261 playing the role of .
+Catalysis involves the residue at position 176 playing the role of .
+Catalysis involves the residue at position 257 playing the role of Proton donor.
+Catalysis involves the residue at position 361 playing the role of .
+Catalysis involves the residue at position 97 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 62 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 300 playing the role of Pros-phosphohistidine intermediate; for HPr 1 activity.
+Catalysis involves the residue at position 424 playing the role of Pros-phosphohistidine intermediate; for HPr 2 activity.
+Catalysis involves the residue at position 65 playing the role of Charge relay system.
+Catalysis involves the residue at position 110 playing the role of Charge relay system.
+Catalysis involves the residue at position 204 playing the role of Charge relay system.
+Catalysis involves the residue at position 118 playing the role of Proton donor.
+Catalysis involves the residue at position 262 playing the role of Nucleophile.
+Catalysis involves the residue at position 190 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 75 playing the role of Nucleophile.
+Catalysis involves the residue at position 165 playing the role of Charge relay system.
+Catalysis involves the residue at position 167 playing the role of Charge relay system.
+Catalysis involves the residue at position 395 playing the role of Proton donor.
+Catalysis involves the residue at position 261 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 194 playing the role of Proton acceptor.
+Catalysis involves the residue at position 94 playing the role of Electrophile.
+Catalysis involves the residue at position 703 playing the role of Proton donor.
+Catalysis involves the residue at position 310 playing the role of .
+Catalysis involves the residue at position 130 playing the role of .
+Catalysis involves the residue at position 146 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 104 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 133 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 161 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 101 playing the role of .
+Catalysis involves the residue at position 104 playing the role of .
+Catalysis involves the residue at position 108 playing the role of .
+Catalysis involves the residue at position 67 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 136 playing the role of For ring-opening step.
+Catalysis involves the residue at position 138 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 143 playing the role of For ring-opening step.
+Catalysis involves the residue at position 138 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 61 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 604 playing the role of .
+Catalysis involves the residue at position 82 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 35 playing the role of Proton acceptor.
+Catalysis involves the residue at position 63 playing the role of Proton donor.
+Catalysis involves the residue at position 598 playing the role of Nucleophile.
+Catalysis involves the residue at position 868 playing the role of Proton acceptor.
+Catalysis involves the residue at position 107 playing the role of Proton donor.
+Catalysis involves the residue at position 55 playing the role of Proton acceptor.
+Catalysis involves the residue at position 127 playing the role of Proton acceptor.
+Catalysis involves the residue at position 63 playing the role of .
+Catalysis involves the residue at position 161 playing the role of Charge relay system.
+Catalysis involves the residue at position 249 playing the role of Proton acceptor.
+Catalysis involves the residue at position 283 playing the role of Nucleophile.
+Catalysis involves the residue at position 461 playing the role of Charge relay system.
+Catalysis involves the residue at position 60 playing the role of Proton donor.
+Catalysis involves the residue at position 301 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 397 playing the role of Proton acceptor.
+Catalysis involves the residue at position 160 playing the role of Proton donor.
+Catalysis involves the residue at position 375 playing the role of Nucleophile.
+Catalysis involves the residue at position 97 playing the role of Proton acceptor.
+Catalysis involves the residue at position 47 playing the role of Nucleophile.
+Catalysis involves the residue at position 7 playing the role of Nucleophile.
+Catalysis involves the residue at position 431 playing the role of .
+Catalysis involves the residue at position 317 playing the role of Proton acceptor.
+Catalysis involves the residue at position 346 playing the role of Proton donor.
+Catalysis involves the residue at position 190 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 66 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 451 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 142 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 79 playing the role of Charge relay system.
+Catalysis involves the residue at position 154 playing the role of Charge relay system.
+Catalysis involves the residue at position 178 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 393 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 524 playing the role of .
+Catalysis involves the residue at position 526 playing the role of .
+Catalysis involves the residue at position 351 playing the role of .
+Catalysis involves the residue at position 132 playing the role of Proton donor.
+Catalysis involves the residue at position 351 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 104 playing the role of Proton donor.
+Catalysis involves the residue at position 134 playing the role of .
+Catalysis involves the residue at position 40 playing the role of Proton donor.
+Catalysis involves the residue at position 83 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 191 playing the role of Proton acceptor.
+Catalysis involves the residue at position 116 playing the role of Proton acceptor.
+Catalysis involves the residue at position 370 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 39 playing the role of Nucleophile.
+Catalysis involves the residue at position 125 playing the role of .
+Catalysis involves the residue at position 462 playing the role of .
+Catalysis involves the residue at position 471 playing the role of .
+Catalysis involves the residue at position 11 playing the role of Nucleophile.
+Catalysis involves the residue at position 529 playing the role of .
+Catalysis involves the residue at position 132 playing the role of Nucleophile.
+Catalysis involves the residue at position 118 playing the role of .
+Catalysis involves the residue at position 96 playing the role of Electrophile.
+Catalysis involves the residue at position 305 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 103 playing the role of Proton acceptor.
+Catalysis involves the residue at position 36 playing the role of Proton donor.
+Catalysis involves the residue at position 101 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 425 playing the role of .
+Catalysis involves the residue at position 429 playing the role of .
+Catalysis involves the residue at position 52 playing the role of Nucleophile.
+Catalysis involves the residue at position 31 playing the role of Proton acceptor.
+Catalysis involves the residue at position 198 playing the role of Proton donor.
+Catalysis involves the residue at position 11 playing the role of .
+Catalysis involves the residue at position 71 playing the role of .
+Catalysis involves the residue at position 125 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 162 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 384 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 306 playing the role of Proton acceptor.
+Catalysis involves the residue at position 472 playing the role of Proton donor.
+Catalysis involves the residue at position 548 playing the role of Nucleophile.
+Catalysis involves the residue at position 320 playing the role of Proton donor.
+Catalysis involves the residue at position 47 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 317 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 137 playing the role of Proton acceptor.
+Catalysis involves the residue at position 2 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 596 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 309 playing the role of Nucleophile.
+Catalysis involves the residue at position 336 playing the role of .
+Catalysis involves the residue at position 353 playing the role of .
+Catalysis involves the residue at position 65 playing the role of Proton acceptor.
+Catalysis involves the residue at position 17 playing the role of Proton acceptor.
+Catalysis involves the residue at position 26 playing the role of .
+Catalysis involves the residue at position 44 playing the role of .
+Catalysis involves the residue at position 64 playing the role of Charge relay system.
+Catalysis involves the residue at position 109 playing the role of Charge relay system.
+Catalysis involves the residue at position 203 playing the role of Charge relay system.
+Catalysis involves the residue at position 7 playing the role of Proton acceptor.
+Catalysis involves the residue at position 114 playing the role of Proton acceptor.
+Catalysis involves the residue at position 165 playing the role of Proton acceptor.
+Catalysis involves the residue at position 284 playing the role of Proton acceptor.
+Catalysis involves the residue at position 138 playing the role of Proton acceptor.
+Catalysis involves the residue at position 41 playing the role of Charge relay system.
+Catalysis involves the residue at position 86 playing the role of Charge relay system.
+Catalysis involves the residue at position 182 playing the role of Charge relay system.
+Catalysis involves the residue at position 170 playing the role of Proton donor.
+Catalysis involves the residue at position 174 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 692 playing the role of .
+Catalysis involves the residue at position 735 playing the role of .
+Catalysis involves the residue at position 600 playing the role of .
+Catalysis involves the residue at position 602 playing the role of .
+Catalysis involves the residue at position 607 playing the role of .
+Catalysis involves the residue at position 934 playing the role of .
+Catalysis involves the residue at position 936 playing the role of .
+Catalysis involves the residue at position 941 playing the role of .
+Catalysis involves the residue at position 208 playing the role of .
+Catalysis involves the residue at position 237 playing the role of .
+Catalysis involves the residue at position 254 playing the role of Proton donor.
+Catalysis involves the residue at position 84 playing the role of Proton acceptor.
+Catalysis involves the residue at position 87 playing the role of Nucleophile.
+Catalysis involves the residue at position 181 playing the role of .
+Catalysis involves the residue at position 196 playing the role of Nucleophile.
+Catalysis involves the residue at position 241 playing the role of .
+Catalysis involves the residue at position 267 playing the role of .
+Catalysis involves the residue at position 276 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 122 playing the role of Proton donor.
+Catalysis involves the residue at position 234 playing the role of Proton acceptor.
+Catalysis involves the residue at position 178 playing the role of Proton acceptor.
+Catalysis involves the residue at position 474 playing the role of Proton acceptor.
+Catalysis involves the residue at position 111 playing the role of .
+Catalysis involves the residue at position 269 playing the role of .
+Catalysis involves the residue at position 292 playing the role of Proton donor.
+Catalysis involves the residue at position 125 playing the role of Nucleophile.
+Catalysis involves the residue at position 221 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 248 playing the role of .
+Catalysis involves the residue at position 365 playing the role of Nucleophile.
+Catalysis involves the residue at position 177 playing the role of Proton donor.
+Catalysis involves the residue at position 211 playing the role of Proton acceptor.
+Catalysis involves the residue at position 215 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 334 playing the role of Proton acceptor.
+Catalysis involves the residue at position 132 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 189 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 164 playing the role of Nucleophile.
+Catalysis involves the residue at position 363 playing the role of .
+Catalysis involves the residue at position 88 playing the role of Nucleophile.
+Catalysis involves the residue at position 189 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 94 playing the role of Proton acceptor.
+Catalysis involves the residue at position 268 playing the role of Nucleophile.
+Catalysis involves the residue at position 153 playing the role of Nucleophile.
+Catalysis involves the residue at position 105 playing the role of Nucleophile.
+Catalysis involves the residue at position 109 playing the role of Proton donor.
+Catalysis involves the residue at position 12 playing the role of .
+Catalysis involves the residue at position 241 playing the role of Proton acceptor.
+Catalysis involves the residue at position 374 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 154 playing the role of Nucleophile.
+Catalysis involves the residue at position 215 playing the role of Charge relay system.
+Catalysis involves the residue at position 268 playing the role of Charge relay system.
+Catalysis involves the residue at position 59 playing the role of Nucleophile.
+Catalysis involves the residue at position 102 playing the role of Proton acceptor.
+Catalysis involves the residue at position 162 playing the role of Proton acceptor.
+Catalysis involves the residue at position 207 playing the role of Proton acceptor.
+Catalysis involves the residue at position 385 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 177 playing the role of .
+Catalysis involves the residue at position 187 playing the role of Proton donor.
+Catalysis involves the residue at position 267 playing the role of Nucleophile.
+Catalysis involves the residue at position 136 playing the role of .
+Catalysis involves the residue at position 391 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 88 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 144 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 247 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 247 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 254 playing the role of .
+Catalysis involves the residue at position 203 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 82 playing the role of .
+Catalysis involves the residue at position 147 playing the role of Proton acceptor.
+Catalysis involves the residue at position 76 playing the role of Proton donor.
+Catalysis involves the residue at position 224 playing the role of Proton acceptor.
+Catalysis involves the residue at position 21 playing the role of Proton donor.
+Catalysis involves the residue at position 151 playing the role of Nucleophile.
+Catalysis involves the residue at position 38 playing the role of Nucleophile.
+Catalysis involves the residue at position 175 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 435 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 444 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 43 playing the role of Proton donor.
+Catalysis involves the residue at position 269 playing the role of Proton acceptor.
+Catalysis involves the residue at position 112 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 139 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 352 playing the role of Proton acceptor.
+Catalysis involves the residue at position 321 playing the role of Proton donor.
+Catalysis involves the residue at position 81 playing the role of Proton acceptor.
+Catalysis involves the residue at position 137 playing the role of .
+Catalysis involves the residue at position 296 playing the role of Nucleophile.
+Catalysis involves the residue at position 481 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 87 playing the role of Proton donor.
+Catalysis involves the residue at position 315 playing the role of Proton acceptor.
+Catalysis involves the residue at position 343 playing the role of Proton donor.
+Catalysis involves the residue at position 76 playing the role of .
+Catalysis involves the residue at position 141 playing the role of Proton acceptor.
+Catalysis involves the residue at position 10 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 175 playing the role of Pros-phosphohistidine intermediate; for EIIB activity.
+Catalysis involves the residue at position 20 playing the role of .
+Catalysis involves the residue at position 38 playing the role of .
+Catalysis involves the residue at position 69 playing the role of Proton donor.
+Catalysis involves the residue at position 363 playing the role of Proton acceptor.
+Catalysis involves the residue at position 344 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 324 playing the role of Nucleophile.
+Catalysis involves the residue at position 358 playing the role of Proton acceptor.
+Catalysis involves the residue at position 69 playing the role of .
+Catalysis involves the residue at position 128 playing the role of Proton acceptor.
+Catalysis involves the residue at position 86 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 120 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 262 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 139 playing the role of Nucleophile.
+Catalysis involves the residue at position 121 playing the role of Proton donor.
+Catalysis involves the residue at position 185 playing the role of Proton acceptor.
+Catalysis involves the residue at position 288 playing the role of Proton donor.
+Catalysis involves the residue at position 312 playing the role of Proton acceptor.
+Catalysis involves the residue at position 340 playing the role of Proton donor.
+Catalysis involves the residue at position 155 playing the role of Nucleophile.
+Catalysis involves the residue at position 377 playing the role of .
+Catalysis involves the residue at position 272 playing the role of Proton donor.
+Catalysis involves the residue at position 293 playing the role of .
+Catalysis involves the residue at position 130 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 168 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 99 playing the role of Nucleophile.
+Catalysis involves the residue at position 102 playing the role of Nucleophile.
+Catalysis involves the residue at position 190 playing the role of .
+Catalysis involves the residue at position 288 playing the role of Nucleophile.
+Catalysis involves the residue at position 101 playing the role of Nucleophile.
+Catalysis involves the residue at position 199 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 155 playing the role of Proton donor.
+Catalysis involves the residue at position 257 playing the role of Nucleophile.
+Catalysis involves the residue at position 65 playing the role of .
+Catalysis involves the residue at position 119 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 156 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 11 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 203 playing the role of .
+Catalysis involves the residue at position 373 playing the role of Nucleophile.
+Catalysis involves the residue at position 235 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 102 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 136 playing the role of Proton acceptor.
+Catalysis involves the residue at position 399 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 264 playing the role of Nucleophile.
+Catalysis involves the residue at position 174 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 122 playing the role of Proton acceptor.
+Catalysis involves the residue at position 268 playing the role of .
+Catalysis involves the residue at position 40 playing the role of Charge relay system.
+Catalysis involves the residue at position 43 playing the role of Charge relay system.
+Catalysis involves the residue at position 337 playing the role of Proton acceptor.
+Catalysis involves the residue at position 245 playing the role of .
+Catalysis involves the residue at position 248 playing the role of Proton acceptor.
+Catalysis involves the residue at position 38 playing the role of Proton donor.
+Catalysis involves the residue at position 101 playing the role of Proton donor.
+Catalysis involves the residue at position 207 playing the role of .
+Catalysis involves the residue at position 281 playing the role of .
+Catalysis involves the residue at position 174 playing the role of Nucleophile.
+Catalysis involves the residue at position 369 playing the role of .
+Catalysis involves the residue at position 371 playing the role of .
+Catalysis involves the residue at position 12 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 90 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 331 playing the role of Nucleophile.
+Catalysis involves the residue at position 430 playing the role of .
+Catalysis involves the residue at position 410 playing the role of .
+Catalysis involves the residue at position 227 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 345 playing the role of Charge relay system.
+Catalysis involves the residue at position 458 playing the role of Charge relay system.
+Catalysis involves the residue at position 197 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 226 playing the role of Proton acceptor.
+Catalysis involves the residue at position 275 playing the role of Nucleophile.
+Catalysis involves the residue at position 440 playing the role of .
+Catalysis involves the residue at position 56 playing the role of .
+Catalysis involves the residue at position 266 playing the role of .
+Catalysis involves the residue at position 273 playing the role of .
+Catalysis involves the residue at position 266 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 145 playing the role of Charge relay system.
+Catalysis involves the residue at position 223 playing the role of Charge relay system.
+Catalysis involves the residue at position 256 playing the role of Charge relay system.
+Catalysis involves the residue at position 44 playing the role of Proton acceptor.
+Catalysis involves the residue at position 90 playing the role of Proton donor.
+Catalysis involves the residue at position 8 playing the role of .
+Catalysis involves the residue at position 179 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 186 playing the role of Proton donor.
+Catalysis involves the residue at position 302 playing the role of .
+Catalysis involves the residue at position 161 playing the role of Proton acceptor.
+Catalysis involves the residue at position 530 playing the role of Proton acceptor.
+Catalysis involves the residue at position 10 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 77 playing the role of Nucleophile.
+Catalysis involves the residue at position 178 playing the role of .
+Catalysis involves the residue at position 180 playing the role of .
+Catalysis involves the residue at position 121 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 219 playing the role of Proton acceptor.
+Catalysis involves the residue at position 324 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 193 playing the role of Charge relay system.
+Catalysis involves the residue at position 325 playing the role of Charge relay system.
+Catalysis involves the residue at position 401 playing the role of Charge relay system.
+Catalysis involves the residue at position 499 playing the role of Proton donor.
+Catalysis involves the residue at position 18 playing the role of .
+Catalysis involves the residue at position 9 playing the role of Nucleophile.
+Catalysis involves the residue at position 50 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 305 playing the role of Proton acceptor.
+Catalysis involves the residue at position 135 playing the role of .
+Catalysis involves the residue at position 148 playing the role of .
+Catalysis involves the residue at position 240 playing the role of .
+Catalysis involves the residue at position 275 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 278 playing the role of Proton acceptor.
+Catalysis involves the residue at position 683 playing the role of Proton donor.
+Catalysis involves the residue at position 334 playing the role of Nucleophile.
+Catalysis involves the residue at position 263 playing the role of Nucleophile.
+Catalysis involves the residue at position 347 playing the role of .
+Catalysis involves the residue at position 349 playing the role of .
+Catalysis involves the residue at position 179 playing the role of Proton acceptor.
+Catalysis involves the residue at position 297 playing the role of Proton acceptor.
+Catalysis involves the residue at position 62 playing the role of .
+Catalysis involves the residue at position 179 playing the role of Nucleophile.
+Catalysis involves the residue at position 185 playing the role of .
+Catalysis involves the residue at position 187 playing the role of .
+Catalysis involves the residue at position 97 playing the role of Electrophile.
+Catalysis involves the residue at position 2 playing the role of For GATase activity.
+Catalysis involves the residue at position 31 playing the role of Nucleophile.
+Catalysis involves the residue at position 192 playing the role of Proton donor.
+Catalysis involves the residue at position 12 playing the role of Charge relay system.
+Catalysis involves the residue at position 60 playing the role of Charge relay system.
+Catalysis involves the residue at position 263 playing the role of Charge relay system.
+Catalysis involves the residue at position 64 playing the role of Proton acceptor.
+Catalysis involves the residue at position 291 playing the role of Proton donor.
+Catalysis involves the residue at position 312 playing the role of .
+Catalysis involves the residue at position 426 playing the role of .
+Catalysis involves the residue at position 74 playing the role of .
+Catalysis involves the residue at position 149 playing the role of Proton acceptor.
+Catalysis involves the residue at position 143 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 128 playing the role of .
+Catalysis involves the residue at position 59 playing the role of Proton acceptor.
+Catalysis involves the residue at position 134 playing the role of Proton donor.
+Catalysis involves the residue at position 166 playing the role of Nucleophile.
+Catalysis involves the residue at position 114 playing the role of Charge relay.
+Catalysis involves the residue at position 247 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 71 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 76 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 91 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 87 playing the role of .
+Catalysis involves the residue at position 974 playing the role of Proton acceptor.
+Catalysis involves the residue at position 417 playing the role of Nucleophile.
+Catalysis involves the residue at position 334 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 100 playing the role of .
+Catalysis involves the residue at position 103 playing the role of .
+Catalysis involves the residue at position 37 playing the role of Proton acceptor.
+Catalysis involves the residue at position 138 playing the role of Proton donor.
+Catalysis involves the residue at position 301 playing the role of Proton acceptor.
+Catalysis involves the residue at position 75 playing the role of .
+Catalysis involves the residue at position 121 playing the role of .
+Catalysis involves the residue at position 1209 playing the role of Nucleophile.
+Catalysis involves the residue at position 1330 playing the role of .
+Catalysis involves the residue at position 1332 playing the role of .
+Catalysis involves the residue at position 332 playing the role of Proton donor.
+Catalysis involves the residue at position 439 playing the role of Nucleophile.
+Catalysis involves the residue at position 105 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 340 playing the role of Proton acceptor.
+Catalysis involves the residue at position 631 playing the role of Proton donor.
+Catalysis involves the residue at position 34 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 259 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 116 playing the role of Nucleophile.
+Catalysis involves the residue at position 126 playing the role of Proton acceptor.
+Catalysis involves the residue at position 128 playing the role of Nucleophile.
+Catalysis involves the residue at position 149 playing the role of Nucleophile.
+Catalysis involves the residue at position 82 playing the role of Charge relay system.
+Catalysis involves the residue at position 137 playing the role of Charge relay system.
+Catalysis involves the residue at position 238 playing the role of Charge relay system.
+Catalysis involves the residue at position 130 playing the role of Proton donor.
+Catalysis involves the residue at position 64 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 468 playing the role of Proton acceptor.
+Catalysis involves the residue at position 303 playing the role of .
+Catalysis involves the residue at position 189 playing the role of Proton acceptor.
+Catalysis involves the residue at position 694 playing the role of Nucleophile.
+Catalysis involves the residue at position 723 playing the role of Proton donor.
+Catalysis involves the residue at position 77 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 173 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 115 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 407 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 166 playing the role of Proton donor.
+Catalysis involves the residue at position 381 playing the role of .
+Catalysis involves the residue at position 158 playing the role of .
+Catalysis involves the residue at position 176 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 81 playing the role of .
+Catalysis involves the residue at position 271 playing the role of Proton acceptor.
+Catalysis involves the residue at position 199 playing the role of Proton donor.
+Catalysis involves the residue at position 221 playing the role of .
+Catalysis involves the residue at position 204 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 425 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 473 playing the role of Proton acceptor.
+Catalysis involves the residue at position 107 playing the role of Nucleophile.
+Catalysis involves the residue at position 132 playing the role of .
+Catalysis involves the residue at position 323 playing the role of Proton acceptor.
+Catalysis involves the residue at position 411 playing the role of Proton donor.
+Catalysis involves the residue at position 236 playing the role of Nucleophile.
+Catalysis involves the residue at position 114 playing the role of Nucleophile.
+Catalysis involves the residue at position 210 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 239 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 382 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 508 playing the role of .
+Catalysis involves the residue at position 510 playing the role of .
+Catalysis involves the residue at position 53 playing the role of Proton acceptor.
+Catalysis involves the residue at position 162 playing the role of Charge relay system.
+Catalysis involves the residue at position 252 playing the role of Proton acceptor.
+Catalysis involves the residue at position 286 playing the role of Nucleophile.
+Catalysis involves the residue at position 464 playing the role of Charge relay system.
+Catalysis involves the residue at position 368 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 110 playing the role of Nucleophile.
+Catalysis involves the residue at position 169 playing the role of Charge relay system.
+Catalysis involves the residue at position 171 playing the role of Charge relay system.
+Catalysis involves the residue at position 254 playing the role of Proton acceptor.
+Catalysis involves the residue at position 410 playing the role of Proton donor.
+Catalysis involves the residue at position 77 playing the role of Charge relay system.
+Catalysis involves the residue at position 152 playing the role of Charge relay system.
+Catalysis involves the residue at position 176 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 89 playing the role of Proton donor.
+Catalysis involves the residue at position 247 playing the role of .
+Catalysis involves the residue at position 270 playing the role of .
+Catalysis involves the residue at position 279 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 429 playing the role of Proton acceptor.
+Catalysis involves the residue at position 162 playing the role of Nucleophile.
+Catalysis involves the residue at position 191 playing the role of Charge relay system.
+Catalysis involves the residue at position 262 playing the role of Charge relay system.
+Catalysis involves the residue at position 232 playing the role of Proton donor.
+Catalysis involves the residue at position 143 playing the role of Nucleophile.
+Catalysis involves the residue at position 304 playing the role of .
+Catalysis involves the residue at position 337 playing the role of .
+Catalysis involves the residue at position 99 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 115 playing the role of .
+Catalysis involves the residue at position 255 playing the role of .
+Catalysis involves the residue at position 63 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 313 playing the role of .
+Catalysis involves the residue at position 457 playing the role of .
+Catalysis involves the residue at position 109 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 312 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 430 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 45 playing the role of .
+Catalysis involves the residue at position 361 playing the role of Proton acceptor.
+Catalysis involves the residue at position 250 playing the role of Proton donor.
+Catalysis involves the residue at position 68 playing the role of Proton acceptor.
+Catalysis involves the residue at position 256 playing the role of .
+Catalysis involves the residue at position 378 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 514 playing the role of .
+Catalysis involves the residue at position 155 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 108 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 82 playing the role of Proton acceptor.
+Catalysis involves the residue at position 136 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 164 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 386 playing the role of .
+Catalysis involves the residue at position 35 playing the role of .
+Catalysis involves the residue at position 52 playing the role of .
+Catalysis involves the residue at position 148 playing the role of Proton donor.
+Catalysis involves the residue at position 113 playing the role of Charge relay system.
+Catalysis involves the residue at position 76 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 185 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 289 playing the role of .
+Catalysis involves the residue at position 236 playing the role of Proton donor.
+Catalysis involves the residue at position 86 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 158 playing the role of Proton acceptor.
+Catalysis involves the residue at position 259 playing the role of Proton acceptor.
+Catalysis involves the residue at position 322 playing the role of .
+Catalysis involves the residue at position 372 playing the role of Nucleophile.
+Catalysis involves the residue at position 111 playing the role of Proton acceptor.
+Catalysis involves the residue at position 172 playing the role of Proton acceptor.
+Catalysis involves the residue at position 48 playing the role of .
+Catalysis involves the residue at position 99 playing the role of .
+Catalysis involves the residue at position 81 playing the role of Nucleophile.
+Catalysis involves the residue at position 177 playing the role of Charge relay system.
+Catalysis involves the residue at position 179 playing the role of Charge relay system.
+Catalysis involves the residue at position 381 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 379 playing the role of Proton acceptor.
+Catalysis involves the residue at position 218 playing the role of Nucleophile.
+Catalysis involves the residue at position 120 playing the role of .
+Catalysis involves the residue at position 285 playing the role of Proton donor.
+Catalysis involves the residue at position 51 playing the role of Proton acceptor.
+Catalysis involves the residue at position 70 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 194 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 84 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 170 playing the role of For GATase activity.
+Catalysis involves the residue at position 172 playing the role of For GATase activity.
+Catalysis involves the residue at position 57 playing the role of .
+Catalysis involves the residue at position 111 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 245 playing the role of Proton donor.
+Catalysis involves the residue at position 67 playing the role of Charge relay system.
+Catalysis involves the residue at position 112 playing the role of Charge relay system.
+Catalysis involves the residue at position 206 playing the role of Charge relay system.
+Catalysis involves the residue at position 53 playing the role of .
+Catalysis involves the residue at position 375 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 235 playing the role of .
+Catalysis involves the residue at position 196 playing the role of Proton acceptor.
+Catalysis involves the residue at position 212 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 171 playing the role of Nucleophile.
+Catalysis involves the residue at position 170 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 338 playing the role of Proton acceptor.
+Catalysis involves the residue at position 98 playing the role of .
+Catalysis involves the residue at position 163 playing the role of Proton acceptor.
+Catalysis involves the residue at position 124 playing the role of .
+Catalysis involves the residue at position 345 playing the role of .
+Catalysis involves the residue at position 378 playing the role of .
+Catalysis involves the residue at position 929 playing the role of Proton acceptor.
+Catalysis involves the residue at position 200 playing the role of Proton donor.
+Catalysis involves the residue at position 298 playing the role of Nucleophile.
+Catalysis involves the residue at position 623 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 150 playing the role of Proton donor.
+Catalysis involves the residue at position 389 playing the role of .
+Catalysis involves the residue at position 364 playing the role of .
+Catalysis involves the residue at position 79 playing the role of .
+Catalysis involves the residue at position 169 playing the role of Proton donor.
+Catalysis involves the residue at position 156 playing the role of Proton acceptor.
+Catalysis involves the residue at position 25 playing the role of Proton acceptor.
+Catalysis involves the residue at position 102 playing the role of Proton donor.
+Catalysis involves the residue at position 200 playing the role of Charge relay system.
+Catalysis involves the residue at position 371 playing the role of Charge relay system.
+Catalysis involves the residue at position 91 playing the role of Proton donor.
+Catalysis involves the residue at position 338 playing the role of Charge relay system.
+Catalysis involves the residue at position 265 playing the role of Nucleophile.
+Catalysis involves the residue at position 28 playing the role of .
+Catalysis involves the residue at position 204 playing the role of Proton acceptor.
+Catalysis involves the residue at position 110 playing the role of Proton acceptor.
+Catalysis involves the residue at position 52 playing the role of Proton acceptor.
+Catalysis involves the residue at position 263 playing the role of .
+Catalysis involves the residue at position 272 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 151 playing the role of Proton acceptor.
+Catalysis involves the residue at position 49 playing the role of Nucleophile.
+Catalysis involves the residue at position 176 playing the role of Charge relay system.
+Catalysis involves the residue at position 178 playing the role of Charge relay system.
+Catalysis involves the residue at position 175 playing the role of Charge relay system.
+Catalysis involves the residue at position 588 playing the role of Proton acceptor.
+Catalysis involves the residue at position 328 playing the role of .
+Catalysis involves the residue at position 375 playing the role of .
+Catalysis involves the residue at position 761 playing the role of Proton donor.
+Catalysis involves the residue at position 159 playing the role of .
+Catalysis involves the residue at position 124 playing the role of Proton acceptor.
+Catalysis involves the residue at position 327 playing the role of Proton acceptor.
+Catalysis involves the residue at position 328 playing the role of Proton acceptor.
+Catalysis involves the residue at position 197 playing the role of .
+Catalysis involves the residue at position 399 playing the role of .
+Catalysis involves the residue at position 5 playing the role of .
+Catalysis involves the residue at position 41 playing the role of Nucleophile.
+Catalysis involves the residue at position 280 playing the role of Proton acceptor.
+Catalysis involves the residue at position 314 playing the role of Nucleophile.
+Catalysis involves the residue at position 131 playing the role of Nucleophile.
+Catalysis involves the residue at position 190 playing the role of Proton donor.
+Catalysis involves the residue at position 94 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 115 playing the role of Proton donor.
+Catalysis involves the residue at position 170 playing the role of Charge relay system.
+Catalysis involves the residue at position 172 playing the role of Charge relay system.
+Catalysis involves the residue at position 72 playing the role of Nucleophile.
+Catalysis involves the residue at position 258 playing the role of .
+Catalysis involves the residue at position 405 playing the role of .
+Catalysis involves the residue at position 427 playing the role of .
+Catalysis involves the residue at position 120 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 133 playing the role of Proton donor.
+Catalysis involves the residue at position 273 playing the role of Proton acceptor.
+Catalysis involves the residue at position 120 playing the role of Charge relay system.
+Catalysis involves the residue at position 151 playing the role of Charge relay system.
+Catalysis involves the residue at position 233 playing the role of Charge relay system.
+Catalysis involves the residue at position 150 playing the role of .
+Catalysis involves the residue at position 243 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 118 playing the role of Proton acceptor.
+Catalysis involves the residue at position 50 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 142 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 235 playing the role of Proton acceptor.
+Catalysis involves the residue at position 103 playing the role of Electrophile.
+Catalysis involves the residue at position 290 playing the role of Proton donor.
+Catalysis involves the residue at position 311 playing the role of .
+Catalysis involves the residue at position 653 playing the role of For protease activity.
+Catalysis involves the residue at position 698 playing the role of Nucleophile; for protease activity.
+Catalysis involves the residue at position 441 playing the role of Nucleophile.
+Catalysis involves the residue at position 752 playing the role of Proton acceptor.
+Catalysis involves the residue at position 246 playing the role of Nucleophile.
+Catalysis involves the residue at position 20 playing the role of Proton acceptor.
+Catalysis involves the residue at position 125 playing the role of Charge relay.
+Catalysis involves the residue at position 16 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 350 playing the role of Proton donor.
+Catalysis involves the residue at position 503 playing the role of .
+Catalysis involves the residue at position 59 playing the role of Proton donor.
+Catalysis involves the residue at position 73 playing the role of Proton donor.
+Catalysis involves the residue at position 217 playing the role of Proton acceptor.
+Catalysis involves the residue at position 71 playing the role of Proton acceptor.
+Catalysis involves the residue at position 278 playing the role of .
+Catalysis involves the residue at position 79 playing the role of Proton acceptor.
+Catalysis involves the residue at position 133 playing the role of Charge relay system.
+Catalysis involves the residue at position 218 playing the role of Charge relay system.
+Catalysis involves the residue at position 127 playing the role of Proton donor.
+Catalysis involves the residue at position 300 playing the role of Proton acceptor.
+Catalysis involves the residue at position 144 playing the role of Proton acceptor.
+Catalysis involves the residue at position 65 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 103 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 199 playing the role of For GATase activity.
+Catalysis involves the residue at position 201 playing the role of For GATase activity.
+Catalysis involves the residue at position 184 playing the role of .
+Catalysis involves the residue at position 49 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 475 playing the role of Proton acceptor.
+Catalysis involves the residue at position 828 playing the role of Proton acceptor.
+Catalysis involves the residue at position 364 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 428 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 145 playing the role of Proton acceptor.
+Catalysis involves the residue at position 181 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 118 playing the role of Nucleophile.
+Catalysis involves the residue at position 214 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 229 playing the role of .
+Catalysis involves the residue at position 346 playing the role of Nucleophile.
+Catalysis involves the residue at position 62 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 411 playing the role of Nucleophile.
+Catalysis involves the residue at position 464 playing the role of Proton donor.
+Catalysis involves the residue at position 78 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 333 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 335 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 45 playing the role of Nucleophile.
+Catalysis involves the residue at position 332 playing the role of Proton acceptor.
+Catalysis involves the residue at position 333 playing the role of Proton acceptor.
+Catalysis involves the residue at position 271 playing the role of Proton donor.
+Catalysis involves the residue at position 469 playing the role of Proton acceptor.
+Catalysis involves the residue at position 213 playing the role of .
+Catalysis involves the residue at position 341 playing the role of Proton acceptor.
+Catalysis involves the residue at position 72 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 141 playing the role of For ring-opening step.
+Catalysis involves the residue at position 143 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 148 playing the role of For ring-opening step.
+Catalysis involves the residue at position 132 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 245 playing the role of Proton acceptor.
+Catalysis involves the residue at position 696 playing the role of Proton donor.
+Catalysis involves the residue at position 88 playing the role of Proton acceptor.
+Catalysis involves the residue at position 403 playing the role of Nucleophile.
+Catalysis involves the residue at position 155 playing the role of .
+Catalysis involves the residue at position 595 playing the role of .
+Catalysis involves the residue at position 34 playing the role of Proton acceptor.
+Catalysis involves the residue at position 201 playing the role of Proton donor.
+Catalysis involves the residue at position 136 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 278 playing the role of Charge relay system.
+Catalysis involves the residue at position 216 playing the role of Proton donor.
+Catalysis involves the residue at position 25 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 58 playing the role of Proton donor.
+Catalysis involves the residue at position 147 playing the role of Proton donor.
+Catalysis involves the residue at position 5 playing the role of Nucleophile.
+Catalysis involves the residue at position 21 playing the role of Proton acceptor.
+Catalysis involves the residue at position 159 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 163 playing the role of Proton donor.
+Catalysis involves the residue at position 756 playing the role of .
+Catalysis involves the residue at position 799 playing the role of .
+Catalysis involves the residue at position 169 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 60 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 97 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 84 playing the role of Proton donor.
+Catalysis involves the residue at position 75 playing the role of Proton acceptor.
+Catalysis involves the residue at position 74 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 190 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 119 playing the role of Charge relay system.
+Catalysis involves the residue at position 237 playing the role of Charge relay system.
+Catalysis involves the residue at position 254 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 446 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 117 playing the role of Proton acceptor.
+Catalysis involves the residue at position 119 playing the role of Proton donor.
+Catalysis involves the residue at position 85 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 50 playing the role of .
+Catalysis involves the residue at position 246 playing the role of Proton acceptor.
+Catalysis involves the residue at position 136 playing the role of Charge relay system.
+Catalysis involves the residue at position 377 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 756 playing the role of Charge relay system.
+Catalysis involves the residue at position 833 playing the role of Charge relay system.
+Catalysis involves the residue at position 866 playing the role of Charge relay system.
+Catalysis involves the residue at position 251 playing the role of .
+Catalysis involves the residue at position 214 playing the role of Nucleophile.
+Catalysis involves the residue at position 222 playing the role of Proton acceptor.
+Catalysis involves the residue at position 226 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 389 playing the role of Proton acceptor.
+Catalysis involves the residue at position 739 playing the role of Proton acceptor.
+Catalysis involves the residue at position 140 playing the role of Nucleophile.
+Catalysis involves the residue at position 301 playing the role of .
+Catalysis involves the residue at position 102 playing the role of Electrophile.
+Catalysis involves the residue at position 174 playing the role of Proton acceptor.
+Catalysis involves the residue at position 570 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 848 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 977 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 36 playing the role of .
+Catalysis involves the residue at position 418 playing the role of Nucleophile.
+Catalysis involves the residue at position 239 playing the role of Proton donor.
+Catalysis involves the residue at position 76 playing the role of Nucleophile.
+Catalysis involves the residue at position 355 playing the role of Proton donor.
+Catalysis involves the residue at position 512 playing the role of .
+Catalysis involves the residue at position 173 playing the role of Proton donor.
+Catalysis involves the residue at position 293 playing the role of Nucleophile.
+Catalysis involves the residue at position 188 playing the role of Proton acceptor.
+Catalysis involves the residue at position 230 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 250 playing the role of Proton acceptor.
+Catalysis involves the residue at position 284 playing the role of Nucleophile.
+Catalysis involves the residue at position 33 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 240 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 38 playing the role of Proton acceptor.
+Catalysis involves the residue at position 145 playing the role of Proton donor.
+Catalysis involves the residue at position 277 playing the role of Proton donor.
+Catalysis involves the residue at position 147 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 98 playing the role of Proton donor.
+Catalysis involves the residue at position 1265 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 182 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 189 playing the role of Proton donor.
+Catalysis involves the residue at position 201 playing the role of Nucleophile.
+Catalysis involves the residue at position 68 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 82 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 229 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 243 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 512 playing the role of Nucleophile.
+Catalysis involves the residue at position 227 playing the role of .
+Catalysis involves the residue at position 15 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 112 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 168 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 255 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 255 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 98 playing the role of Nucleophile.
+Catalysis involves the residue at position 354 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 37 playing the role of Proton donor.
+Catalysis involves the residue at position 96 playing the role of Nucleophile.
+Catalysis involves the residue at position 62 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 128 playing the role of For ring-opening step.
+Catalysis involves the residue at position 130 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 135 playing the role of For ring-opening step.
+Catalysis involves the residue at position 78 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 536 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 525 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 660 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 702 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 973 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1304 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1493 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 253 playing the role of .
+Catalysis involves the residue at position 176 playing the role of Proton acceptor.
+Catalysis involves the residue at position 127 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 463 playing the role of Proton donor.
+Catalysis involves the residue at position 357 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 88 playing the role of .
+Catalysis involves the residue at position 151 playing the role of Proton donor.
+Catalysis involves the residue at position 125 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 258 playing the role of Proton acceptor.
+Catalysis involves the residue at position 165 playing the role of Proton donor.
+Catalysis involves the residue at position 186 playing the role of Nucleophile.
+Catalysis involves the residue at position 204 playing the role of .
+Catalysis involves the residue at position 388 playing the role of .
+Catalysis involves the residue at position 448 playing the role of .
+Catalysis involves the residue at position 379 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 515 playing the role of .
+Catalysis involves the residue at position 152 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 244 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 436 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 249 playing the role of Proton donor.
+Catalysis involves the residue at position 361 playing the role of Nucleophile.
+Catalysis involves the residue at position 64 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 69 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 84 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 201 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 40 playing the role of .
+Catalysis involves the residue at position 754 playing the role of Charge relay system.
+Catalysis involves the residue at position 831 playing the role of Charge relay system.
+Catalysis involves the residue at position 864 playing the role of Charge relay system.
+Catalysis involves the residue at position 35 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 253 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 63 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 402 playing the role of Charge relay system.
+Catalysis involves the residue at position 450 playing the role of Charge relay system.
+Catalysis involves the residue at position 546 playing the role of Charge relay system.
+Catalysis involves the residue at position 222 playing the role of Nucleophile.
+Catalysis involves the residue at position 90 playing the role of Proton acceptor.
+Catalysis involves the residue at position 193 playing the role of Nucleophile.
+Catalysis involves the residue at position 218 playing the role of .
+Catalysis involves the residue at position 324 playing the role of .
+Catalysis involves the residue at position 40 playing the role of Proton acceptor.
+Catalysis involves the residue at position 144 playing the role of Proton donor.
+Catalysis involves the residue at position 661 playing the role of .
+Catalysis involves the residue at position 58 playing the role of Proton acceptor.
+Catalysis involves the residue at position 85 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 151 playing the role of .
+Catalysis involves the residue at position 170 playing the role of .
+Catalysis involves the residue at position 114 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 80 playing the role of .
+Catalysis involves the residue at position 240 playing the role of Proton donor.
+Catalysis involves the residue at position 15 playing the role of .
+Catalysis involves the residue at position 48 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 242 playing the role of Proton acceptor.
+Catalysis involves the residue at position 380 playing the role of Proton acceptor.
+Catalysis involves the residue at position 380 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 506 playing the role of .
+Catalysis involves the residue at position 24 playing the role of Proton acceptor.
+Catalysis involves the residue at position 150 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 249 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 13 playing the role of Nucleophile.
+Catalysis involves the residue at position 92 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 154 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 66 playing the role of Charge relay system.
+Catalysis involves the residue at position 208 playing the role of Charge relay system.
+Catalysis involves the residue at position 656 playing the role of Proton donor.
+Catalysis involves the residue at position 273 playing the role of Charge relay system.
+Catalysis involves the residue at position 405 playing the role of Charge relay system.
+Catalysis involves the residue at position 481 playing the role of Charge relay system.
+Catalysis involves the residue at position 579 playing the role of Proton donor.
+Catalysis involves the residue at position 364 playing the role of Proton acceptor.
+Catalysis involves the residue at position 200 playing the role of .
+Catalysis involves the residue at position 167 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 201 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 100 playing the role of Nucleophile.
+Catalysis involves the residue at position 196 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 124 playing the role of Proton donor.
+Catalysis involves the residue at position 188 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 318 playing the role of .
+Catalysis involves the residue at position 73 playing the role of Charge relay system.
+Catalysis involves the residue at position 123 playing the role of Charge relay system.
+Catalysis involves the residue at position 217 playing the role of Charge relay system.
+Catalysis involves the residue at position 247 playing the role of Nucleophile.
+Catalysis involves the residue at position 331 playing the role of .
+Catalysis involves the residue at position 333 playing the role of .
+Catalysis involves the residue at position 295 playing the role of .
+Catalysis involves the residue at position 223 playing the role of Nucleophile.
+Catalysis involves the residue at position 464 playing the role of Proton acceptor.
+Catalysis involves the residue at position 553 playing the role of Proton acceptor.
+Catalysis involves the residue at position 596 playing the role of .
+Catalysis involves the residue at position 195 playing the role of Nucleophile.
+Catalysis involves the residue at position 623 playing the role of .
+Catalysis involves the residue at position 686 playing the role of Proton donor.
+Catalysis involves the residue at position 32 playing the role of .
+Catalysis involves the residue at position 364 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 71 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 443 playing the role of .
+Catalysis involves the residue at position 296 playing the role of Proton acceptor.
+Catalysis involves the residue at position 324 playing the role of Proton donor.
+Catalysis involves the residue at position 134 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 162 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 99 playing the role of Electrophile.
+Catalysis involves the residue at position 296 playing the role of .
+Catalysis involves the residue at position 267 playing the role of Proton acceptor.
+Catalysis involves the residue at position 46 playing the role of .
+Catalysis involves the residue at position 279 playing the role of .
+Catalysis involves the residue at position 53 playing the role of Charge relay system.
+Catalysis involves the residue at position 92 playing the role of Charge relay system.
+Catalysis involves the residue at position 213 playing the role of Charge relay system.
+Catalysis involves the residue at position 162 playing the role of .
+Catalysis involves the residue at position 364 playing the role of Nucleophile.
+Catalysis involves the residue at position 221 playing the role of Nucleophile.
+Catalysis involves the residue at position 518 playing the role of Proton acceptor.
+Catalysis involves the residue at position 383 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 521 playing the role of .
+Catalysis involves the residue at position 523 playing the role of .
+Catalysis involves the residue at position 229 playing the role of Proton donor.
+Catalysis involves the residue at position 157 playing the role of Charge relay system.
+Catalysis involves the residue at position 188 playing the role of Charge relay system.
+Catalysis involves the residue at position 343 playing the role of Charge relay system.
+Catalysis involves the residue at position 119 playing the role of Nucleophile.
+Catalysis involves the residue at position 19 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 321 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 514 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 255 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 274 playing the role of .
+Catalysis involves the residue at position 46 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 128 playing the role of Proton donor.
+Catalysis involves the residue at position 106 playing the role of Charge relay system.
+Catalysis involves the residue at position 160 playing the role of Charge relay system.
+Catalysis involves the residue at position 192 playing the role of Charge relay system.
+Catalysis involves the residue at position 198 playing the role of .
+Catalysis involves the residue at position 456 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 73 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 183 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 329 playing the role of .
+Catalysis involves the residue at position 424 playing the role of .
+Catalysis involves the residue at position 112 playing the role of Nucleophile.
+Catalysis involves the residue at position 99 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 392 playing the role of Proton acceptor.
+Catalysis involves the residue at position 422 playing the role of Proton acceptor.
+Catalysis involves the residue at position 238 playing the role of Proton acceptor.
+Catalysis involves the residue at position 207 playing the role of Proton donor.
+Catalysis involves the residue at position 101 playing the role of Electrophile.
+Catalysis involves the residue at position 171 playing the role of Proton acceptor.
+Catalysis involves the residue at position 72 playing the role of Proton donor.
+Catalysis involves the residue at position 166 playing the role of .
+Catalysis involves the residue at position 48 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 369 playing the role of Proton donor.
+Catalysis involves the residue at position 400 playing the role of .
+Catalysis involves the residue at position 793 playing the role of Proton acceptor.
+Catalysis involves the residue at position 210 playing the role of .
+Catalysis involves the residue at position 208 playing the role of Proton donor.
+Catalysis involves the residue at position 76 playing the role of Charge relay system.
+Catalysis involves the residue at position 71 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 270 playing the role of Proton donor.
+Catalysis involves the residue at position 303 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 366 playing the role of Charge relay system.
+Catalysis involves the residue at position 422 playing the role of Charge relay system.
+Catalysis involves the residue at position 61 playing the role of Proton donor.
+Catalysis involves the residue at position 90 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 147 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 254 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 254 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 1904 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 158 playing the role of Proton donor.
+Catalysis involves the residue at position 162 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 42 playing the role of Proton acceptor.
+Catalysis involves the residue at position 69 playing the role of Proton acceptor.
+Catalysis involves the residue at position 174 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 356 playing the role of Proton donor.
+Catalysis involves the residue at position 387 playing the role of .
+Catalysis involves the residue at position 260 playing the role of Charge relay system.
+Catalysis involves the residue at position 683 playing the role of Proton acceptor.
+Catalysis involves the residue at position 383 playing the role of Proton acceptor.
+Catalysis involves the residue at position 504 playing the role of Proton acceptor.
+Catalysis involves the residue at position 889 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1010 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1395 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1516 playing the role of Proton acceptor.
+Catalysis involves the residue at position 65 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 70 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 85 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 80 playing the role of Proton donor.
+Catalysis involves the residue at position 457 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 11 playing the role of Proton donor.
+Catalysis involves the residue at position 439 playing the role of Proton acceptor.
+Catalysis involves the residue at position 97 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 335 playing the role of Nucleophile.
+Catalysis involves the residue at position 408 playing the role of .
+Catalysis involves the residue at position 120 playing the role of Proton acceptor.
+Catalysis involves the residue at position 239 playing the role of Proton acceptor.
+Catalysis involves the residue at position 156 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 237 playing the role of Proton donor.
+Catalysis involves the residue at position 291 playing the role of .
+Catalysis involves the residue at position 365 playing the role of .
+Catalysis involves the residue at position 246 playing the role of .
+Catalysis involves the residue at position 418 playing the role of .
+Catalysis involves the residue at position 276 playing the role of .
+Catalysis involves the residue at position 71 playing the role of Proton donor.
+Catalysis involves the residue at position 413 playing the role of S-acetylcysteine intermediate.
+Catalysis involves the residue at position 414 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 76 playing the role of Proton acceptor.
+Catalysis involves the residue at position 57 playing the role of Nucleophile.
+Catalysis involves the residue at position 290 playing the role of .
+Catalysis involves the residue at position 132 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 110 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 370 playing the role of Proton acceptor.
+Catalysis involves the residue at position 400 playing the role of Proton acceptor.
+Catalysis involves the residue at position 230 playing the role of Proton acceptor.
+Catalysis involves the residue at position 203 playing the role of Proton acceptor.
+Catalysis involves the residue at position 227 playing the role of Proton donor.
+Catalysis involves the residue at position 297 playing the role of .
+Catalysis involves the residue at position 153 playing the role of .
+Catalysis involves the residue at position 60 playing the role of Nucleophile.
+Catalysis involves the residue at position 114 playing the role of Proton donor.
+Catalysis involves the residue at position 168 playing the role of .
+Catalysis involves the residue at position 195 playing the role of .
+Catalysis involves the residue at position 226 playing the role of Nucleophile.
+Catalysis involves the residue at position 374 playing the role of Proton donor.
+Catalysis involves the residue at position 431 playing the role of Proton acceptor.
+Catalysis involves the residue at position 167 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 1574 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 451 playing the role of Proton acceptor.
+Catalysis involves the residue at position 299 playing the role of Nucleophile.
+Catalysis involves the residue at position 303 playing the role of Nucleophile.
+Catalysis involves the residue at position 231 playing the role of Proton acceptor.
+Catalysis involves the residue at position 410 playing the role of Nucleophile.
+Catalysis involves the residue at position 135 playing the role of Charge relay system.
+Catalysis involves the residue at position 72 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 212 playing the role of .
+Catalysis involves the residue at position 299 playing the role of .
+Catalysis involves the residue at position 326 playing the role of .
+Catalysis involves the residue at position 255 playing the role of Proton acceptor.
+Catalysis involves the residue at position 218 playing the role of Proton donor.
+Catalysis involves the residue at position 338 playing the role of .
+Catalysis involves the residue at position 420 playing the role of Proton donor.
+Catalysis involves the residue at position 610 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 699 playing the role of For GATase activity.
+Catalysis involves the residue at position 701 playing the role of For GATase activity.
+Catalysis involves the residue at position 194 playing the role of Nucleophile.
+Catalysis involves the residue at position 230 playing the role of Proton donor.
+Catalysis involves the residue at position 304 playing the role of Proton acceptor.
+Catalysis involves the residue at position 58 playing the role of Charge relay system.
+Catalysis involves the residue at position 121 playing the role of Charge relay system.
+Catalysis involves the residue at position 175 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 407 playing the role of .
+Catalysis involves the residue at position 129 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 428 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 489 playing the role of Charge relay system.
+Catalysis involves the residue at position 608 playing the role of Charge relay system.
+Catalysis involves the residue at position 323 playing the role of Nucleophile.
+Catalysis involves the residue at position 198 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 360 playing the role of Charge relay system.
+Catalysis involves the residue at position 392 playing the role of Charge relay system.
+Catalysis involves the residue at position 223 playing the role of .
+Catalysis involves the residue at position 145 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 108 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 223 playing the role of Proton donor.
+Catalysis involves the residue at position 217 playing the role of Proton donor.
+Catalysis involves the residue at position 60 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 212 playing the role of Nucleophile.
+Catalysis involves the residue at position 248 playing the role of Proton donor.
+Catalysis involves the residue at position 281 playing the role of Nucleophile.
+Catalysis involves the residue at position 182 playing the role of .
+Catalysis involves the residue at position 285 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1264 playing the role of Proton acceptor.
+Catalysis involves the residue at position 200 playing the role of Proton acceptor.
+Catalysis involves the residue at position 203 playing the role of Proton donor.
+Catalysis involves the residue at position 326 playing the role of Proton acceptor.
+Catalysis involves the residue at position 53 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 13 playing the role of .
+Catalysis involves the residue at position 225 playing the role of .
+Catalysis involves the residue at position 234 playing the role of .
+Catalysis involves the residue at position 263 playing the role of Proton acceptor.
+Catalysis involves the residue at position 56 playing the role of Proton acceptor.
+Catalysis involves the residue at position 218 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 130 playing the role of Nucleophile.
+Catalysis involves the residue at position 92 playing the role of .
+Catalysis involves the residue at position 278 playing the role of Nucleophile.
+Catalysis involves the residue at position 759 playing the role of Charge relay system.
+Catalysis involves the residue at position 836 playing the role of Charge relay system.
+Catalysis involves the residue at position 869 playing the role of Charge relay system.
+Catalysis involves the residue at position 209 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 150 playing the role of Proton acceptor.
+Catalysis involves the residue at position 434 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 436 playing the role of Proton acceptor.
+Catalysis involves the residue at position 547 playing the role of .
+Catalysis involves the residue at position 253 playing the role of Proton donor.
+Catalysis involves the residue at position 235 playing the role of Charge relay system.
+Catalysis involves the residue at position 343 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 116 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 324 playing the role of Proton acceptor.
+Catalysis involves the residue at position 325 playing the role of Proton acceptor.
+Catalysis involves the residue at position 94 playing the role of .
+Catalysis involves the residue at position 107 playing the role of Proton acceptor.
+Catalysis involves the residue at position 346 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 157 playing the role of Proton donor.
+Catalysis involves the residue at position 318 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 192 playing the role of .
+Catalysis involves the residue at position 112 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 26 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 492 playing the role of .
+Catalysis involves the residue at position 569 playing the role of .
+Catalysis involves the residue at position 573 playing the role of .
+Catalysis involves the residue at position 418 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 47 playing the role of Proton donor.
+Catalysis involves the residue at position 286 playing the role of Proton donor.
+Catalysis involves the residue at position 395 playing the role of Nucleophile.
+Catalysis involves the residue at position 193 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 89 playing the role of .
+Catalysis involves the residue at position 227 playing the role of Nucleophile.
+Catalysis involves the residue at position 251 playing the role of Proton donor.
+Catalysis involves the residue at position 299 playing the role of Pros-phosphohistidine intermediate; for HPr activity.
+Catalysis involves the residue at position 176 playing the role of Proton donor.
+Catalysis involves the residue at position 77 playing the role of Proton acceptor.
+Catalysis involves the residue at position 194 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 141 playing the role of Nucleophile.
+Catalysis involves the residue at position 160 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 95 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 698 playing the role of Proton donor.
+Catalysis involves the residue at position 109 playing the role of .
+Catalysis involves the residue at position 447 playing the role of Proton acceptor.
+Catalysis involves the residue at position 226 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 177 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 49 playing the role of .
+Catalysis involves the residue at position 453 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 657 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 135 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 80 playing the role of Charge relay system.
+Catalysis involves the residue at position 179 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 62 playing the role of Proton donor.
+Catalysis involves the residue at position 93 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 326 playing the role of Nucleophile.
+Catalysis involves the residue at position 432 playing the role of .
+Catalysis involves the residue at position 327 playing the role of Proton donor.
+Catalysis involves the residue at position 507 playing the role of .
+Catalysis involves the residue at position 419 playing the role of .
+Catalysis involves the residue at position 445 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 55 playing the role of Nucleophile.
+Catalysis involves the residue at position 29 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 415 playing the role of Nucleophile.
+Catalysis involves the residue at position 162 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 294 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 331 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 460 playing the role of Proton acceptor.
+Catalysis involves the residue at position 19 playing the role of Nucleophile.
+Catalysis involves the residue at position 51 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 426 playing the role of Proton donor.
+Catalysis involves the residue at position 135 playing the role of Proton donor.
+Catalysis involves the residue at position 95 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 264 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 173 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 210 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 211 playing the role of Proton donor.
+Catalysis involves the residue at position 201 playing the role of .
+Catalysis involves the residue at position 208 playing the role of Proton acceptor.
+Catalysis involves the residue at position 285 playing the role of Nucleophile.
+Catalysis involves the residue at position 230 playing the role of Nucleophile.
+Catalysis involves the residue at position 235 playing the role of Proton donor.
+Catalysis involves the residue at position 314 playing the role of Proton acceptor.
+Catalysis involves the residue at position 342 playing the role of Proton donor.
+Catalysis involves the residue at position 129 playing the role of Nucleophile.
+Catalysis involves the residue at position 138 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 85 playing the role of Nucleophile.
+Catalysis involves the residue at position 336 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 1563 playing the role of .
+Catalysis involves the residue at position 236 playing the role of .
+Catalysis involves the residue at position 265 playing the role of .
+Catalysis involves the residue at position 284 playing the role of Proton donor.
+Catalysis involves the residue at position 58 playing the role of Nucleophile.
+Catalysis involves the residue at position 119 playing the role of Proton acceptor.
+Catalysis involves the residue at position 260 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 252 playing the role of .
+Catalysis involves the residue at position 99 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 298 playing the role of Proton donor.
+Catalysis involves the residue at position 189 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 288 playing the role of Charge relay system.
+Catalysis involves the residue at position 292 playing the role of Charge relay system.
+Catalysis involves the residue at position 504 playing the role of Charge relay system.
+Catalysis involves the residue at position 269 playing the role of Nucleophile.
+Catalysis involves the residue at position 355 playing the role of .
+Catalysis involves the residue at position 157 playing the role of Nucleophile.
+Catalysis involves the residue at position 357 playing the role of .
+Catalysis involves the residue at position 798 playing the role of Proton acceptor.
+Catalysis involves the residue at position 9 playing the role of .
+Catalysis involves the residue at position 325 playing the role of Nucleophile.
+Catalysis involves the residue at position 423 playing the role of .
+Catalysis involves the residue at position 331 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 357 playing the role of Charge relay system.
+Catalysis involves the residue at position 406 playing the role of Charge relay system.
+Catalysis involves the residue at position 513 playing the role of Charge relay system.
+Catalysis involves the residue at position 173 playing the role of Proton acceptor.
+Catalysis involves the residue at position 480 playing the role of Proton acceptor.
+Catalysis involves the residue at position 165 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 256 playing the role of Proton acceptor.
+Catalysis involves the residue at position 51 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 352 playing the role of .
+Catalysis involves the residue at position 177 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 51 playing the role of Nucleophile.
+Catalysis involves the residue at position 158 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 162 playing the role of Proton donor.
+Catalysis involves the residue at position 31 playing the role of .
+Catalysis involves the residue at position 68 playing the role of Proton donor.
+Catalysis involves the residue at position 207 playing the role of Nucleophile.
+Catalysis involves the residue at position 244 playing the role of Proton donor.
+Catalysis involves the residue at position 318 playing the role of Proton acceptor.
+Catalysis involves the residue at position 89 playing the role of Nucleophile.
+Catalysis involves the residue at position 272 playing the role of Nucleophile.
+Catalysis involves the residue at position 202 playing the role of Proton donor.
+Catalysis involves the residue at position 300 playing the role of Nucleophile.
+Catalysis involves the residue at position 245 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 346 playing the role of Proton acceptor.
+Catalysis involves the residue at position 187 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 221 playing the role of Charge relay system.
+Catalysis involves the residue at position 254 playing the role of Charge relay system.
+Catalysis involves the residue at position 156 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 386 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 407 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 329 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 33 playing the role of Nucleophile.
+Catalysis involves the residue at position 36 playing the role of Nucleophile.
+Catalysis involves the residue at position 190 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 503 playing the role of Proton donor.
+Catalysis involves the residue at position 307 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 372 playing the role of .
+Catalysis involves the residue at position 396 playing the role of .
+Catalysis involves the residue at position 115 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 591 playing the role of Proton donor.
+Catalysis involves the residue at position 85 playing the role of Charge relay system.
+Catalysis involves the residue at position 65 playing the role of Nucleophile.
+Catalysis involves the residue at position 21 playing the role of .
+Catalysis involves the residue at position 274 playing the role of Proton acceptor.
+Catalysis involves the residue at position 702 playing the role of Proton donor.
+Catalysis involves the residue at position 107 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 261 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 80 playing the role of Nucleophile.
+Catalysis involves the residue at position 73 playing the role of Nucleophile.
+Catalysis involves the residue at position 215 playing the role of Proton acceptor.
+Catalysis involves the residue at position 282 playing the role of Charge relay system.
+Catalysis involves the residue at position 384 playing the role of Charge relay system.
+Catalysis involves the residue at position 170 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 89 playing the role of For formimidoyltransferase activity.
+Catalysis involves the residue at position 134 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 74 playing the role of Proton acceptor.
+Catalysis involves the residue at position 146 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 279 playing the role of Proton acceptor.
+Catalysis involves the residue at position 308 playing the role of .
+Catalysis involves the residue at position 186 playing the role of Proton acceptor.
+Catalysis involves the residue at position 336 playing the role of Nucleophile.
+Catalysis involves the residue at position 371 playing the role of Proton donor.
+Catalysis involves the residue at position 200 playing the role of Nucleophile.
+Catalysis involves the residue at position 557 playing the role of Charge relay system.
+Catalysis involves the residue at position 643 playing the role of Charge relay system.
+Catalysis involves the residue at position 688 playing the role of Charge relay system.
+Catalysis involves the residue at position 587 playing the role of .
+Catalysis involves the residue at position 200 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 97 playing the role of .
+Catalysis involves the residue at position 260 playing the role of .
+Catalysis involves the residue at position 90 playing the role of .
+Catalysis involves the residue at position 227 playing the role of Proton acceptor.
+Catalysis involves the residue at position 2 playing the role of Proton acceptor; via imino nitrogen.
+Catalysis involves the residue at position 355 playing the role of Charge relay system.
+Catalysis involves the residue at position 430 playing the role of Charge relay system.
+Catalysis involves the residue at position 507 playing the role of Charge relay system.
+Catalysis involves the residue at position 223 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 290 playing the role of Charge relay system.
+Catalysis involves the residue at position 327 playing the role of Charge relay system.
+Catalysis involves the residue at position 438 playing the role of .
+Catalysis involves the residue at position 260 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 22 playing the role of Nucleophile.
+Catalysis involves the residue at position 24 playing the role of Proton donor.
+Catalysis involves the residue at position 125 playing the role of Proton acceptor.
+Catalysis involves the residue at position 183 playing the role of Proton donor.
+Catalysis involves the residue at position 252 playing the role of Nucleophile.
+Catalysis involves the residue at position 122 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 168 playing the role of Nucleophile.
+Catalysis involves the residue at position 280 playing the role of Charge relay system.
+Catalysis involves the residue at position 146 playing the role of .
+Catalysis involves the residue at position 185 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 122 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 104 playing the role of Nucleophile.
+Catalysis involves the residue at position 305 playing the role of Proton donor.
+Catalysis involves the residue at position 405 playing the role of Proton acceptor.
+Catalysis involves the residue at position 343 playing the role of .
+Catalysis involves the residue at position 115 playing the role of Charge relay system.
+Catalysis involves the residue at position 209 playing the role of Charge relay system.
+Catalysis involves the residue at position 380 playing the role of .
+Catalysis involves the residue at position 384 playing the role of .
+Catalysis involves the residue at position 288 playing the role of Proton acceptor.
+Catalysis involves the residue at position 78 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 434 playing the role of Proton acceptor.
+Catalysis involves the residue at position 266 playing the role of Proton acceptor.
+Catalysis involves the residue at position 546 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 681 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 724 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 993 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1327 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1518 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 10 playing the role of .
+Catalysis involves the residue at position 605 playing the role of Proton acceptor.
+Catalysis involves the residue at position 244 playing the role of Proton acceptor.
+Catalysis involves the residue at position 325 playing the role of Proton donor.
+Catalysis involves the residue at position 546 playing the role of .
+Catalysis involves the residue at position 176 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 373 playing the role of .
+Catalysis involves the residue at position 137 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 166 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 43 playing the role of Proton acceptor.
+Catalysis involves the residue at position 207 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 467 playing the role of Charge relay system.
+Catalysis involves the residue at position 742 playing the role of Proton acceptor.
+Catalysis involves the residue at position 222 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 351 playing the role of Proton donor.
+Catalysis involves the residue at position 382 playing the role of .
+Catalysis involves the residue at position 511 playing the role of .
+Catalysis involves the residue at position 84 playing the role of .
+Catalysis involves the residue at position 314 playing the role of .
+Catalysis involves the residue at position 358 playing the role of .
+Catalysis involves the residue at position 96 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 101 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 44 playing the role of Proton donor.
+Catalysis involves the residue at position 409 playing the role of Charge relay system.
+Catalysis involves the residue at position 284 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 105 playing the role of Electrophile.
+Catalysis involves the residue at position 199 playing the role of Charge relay system.
+Catalysis involves the residue at position 229 playing the role of Charge relay system.
+Catalysis involves the residue at position 307 playing the role of Charge relay system.
+Catalysis involves the residue at position 197 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 175 playing the role of .
+Catalysis involves the residue at position 93 playing the role of Proton donor.
+Catalysis involves the residue at position 209 playing the role of .
+Catalysis involves the residue at position 145 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 213 playing the role of Nucleophile.
+Catalysis involves the residue at position 519 playing the role of .
+Catalysis involves the residue at position 201 playing the role of Proton acceptor.
+Catalysis involves the residue at position 159 playing the role of Nucleophile.
+Catalysis involves the residue at position 183 playing the role of Charge relay system.
+Catalysis involves the residue at position 193 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 157 playing the role of Proton acceptor.
+Catalysis involves the residue at position 46 playing the role of Proton acceptor.
+Catalysis involves the residue at position 333 playing the role of Nucleophile.
+Catalysis involves the residue at position 354 playing the role of .
+Catalysis involves the residue at position 244 playing the role of Nucleophile.
+Catalysis involves the residue at position 30 playing the role of Nucleophile.
+Catalysis involves the residue at position 405 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 342 playing the role of Nucleophile.
+Catalysis involves the residue at position 832 playing the role of Proton acceptor.
+Catalysis involves the residue at position 286 playing the role of .
+Catalysis involves the residue at position 320 playing the role of .
+Catalysis involves the residue at position 50 playing the role of Proton acceptor.
+Catalysis involves the residue at position 369 playing the role of Nucleophile.
+Catalysis involves the residue at position 133 playing the role of .
+Catalysis involves the residue at position 135 playing the role of Nucleophile.
+Catalysis involves the residue at position 25 playing the role of .
+Catalysis involves the residue at position 349 playing the role of Proton donor.
+Catalysis involves the residue at position 509 playing the role of .
+Catalysis involves the residue at position 201 playing the role of Charge relay system.
+Catalysis involves the residue at position 518 playing the role of .
+Catalysis involves the residue at position 520 playing the role of .
+Catalysis involves the residue at position 785 playing the role of .
+Catalysis involves the residue at position 1049 playing the role of .
+Catalysis involves the residue at position 246 playing the role of Proton donor.
+Catalysis involves the residue at position 251 playing the role of Proton acceptor.
+Catalysis involves the residue at position 454 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 564 playing the role of .
+Catalysis involves the residue at position 140 playing the role of Proton donor.
+Catalysis involves the residue at position 280 playing the role of Nucleophile.
+Catalysis involves the residue at position 333 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 625 playing the role of Proton acceptor.
+Catalysis involves the residue at position 289 playing the role of Proton acceptor.
+Catalysis involves the residue at position 68 playing the role of Nucleophile.
+Catalysis involves the residue at position 61 playing the role of Proton acceptor.
+Catalysis involves the residue at position 847 playing the role of Proton acceptor.
+Catalysis involves the residue at position 734 playing the role of .
+Catalysis involves the residue at position 804 playing the role of .
+Catalysis involves the residue at position 980 playing the role of .
+Catalysis involves the residue at position 164 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 135 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 181 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 152 playing the role of Nucleophile.
+Catalysis involves the residue at position 997 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 232 playing the role of Charge relay system.
+Catalysis involves the residue at position 281 playing the role of Charge relay system.
+Catalysis involves the residue at position 383 playing the role of Charge relay system.
+Catalysis involves the residue at position 120 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 71 playing the role of Charge relay system.
+Catalysis involves the residue at position 116 playing the role of Charge relay system.
+Catalysis involves the residue at position 210 playing the role of Charge relay system.
+Catalysis involves the residue at position 838 playing the role of Proton acceptor.
+Catalysis involves the residue at position 206 playing the role of Proton donor.
+Catalysis involves the residue at position 210 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 80 playing the role of Proton acceptor.
+Catalysis involves the residue at position 559 playing the role of Proton donor.
+Catalysis involves the residue at position 34 playing the role of Proton donor.
+Catalysis involves the residue at position 115 playing the role of Proton acceptor.
+Catalysis involves the residue at position 124 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 113 playing the role of Proton acceptor.
+Catalysis involves the residue at position 363 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 720 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 450 playing the role of Proton acceptor.
+Catalysis involves the residue at position 215 playing the role of .
+Catalysis involves the residue at position 300 playing the role of Charge relay system.
+Catalysis involves the residue at position 304 playing the role of Charge relay system.
+Catalysis involves the residue at position 561 playing the role of Charge relay system.
+Catalysis involves the residue at position 110 playing the role of .
+Catalysis involves the residue at position 58 playing the role of .
+Catalysis involves the residue at position 410 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 85 playing the role of Proton donor.
+Catalysis involves the residue at position 390 playing the role of .
+Catalysis involves the residue at position 277 playing the role of Nucleophile.
+Catalysis involves the residue at position 190 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 98 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 280 playing the role of .
+Catalysis involves the residue at position 215 playing the role of Nucleophile.
+Catalysis involves the residue at position 220 playing the role of Proton donor.
+Catalysis involves the residue at position 257 playing the role of Charge relay system.
+Catalysis involves the residue at position 345 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 302 playing the role of Proton acceptor.
+Catalysis involves the residue at position 330 playing the role of Proton donor.
+Catalysis involves the residue at position 251 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 226 playing the role of Charge relay system.
+Catalysis involves the residue at position 623 playing the role of Proton acceptor.
+Catalysis involves the residue at position 141 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 354 playing the role of Proton acceptor.
+Catalysis involves the residue at position 434 playing the role of .
+Catalysis involves the residue at position 828 playing the role of .
+Catalysis involves the residue at position 1204 playing the role of Proton acceptor.
+Catalysis involves the residue at position 123 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 359 playing the role of .
+Catalysis involves the residue at position 442 playing the role of Proton donor.
+Catalysis involves the residue at position 96 playing the role of .
+Catalysis involves the residue at position 267 playing the role of Charge relay system.
+Catalysis involves the residue at position 411 playing the role of Charge relay system.
+Catalysis involves the residue at position 66 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 71 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 86 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 422 playing the role of Proton donor.
+Catalysis involves the residue at position 618 playing the role of Proton acceptor.
+Catalysis involves the residue at position 185 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 74 playing the role of Nucleophile.
+Catalysis involves the residue at position 90 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 345 playing the role of Proton donor.
+Catalysis involves the residue at position 376 playing the role of .
+Catalysis involves the residue at position 335 playing the role of Proton acceptor.
+Catalysis involves the residue at position 194 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 225 playing the role of Proton acceptor.
+Catalysis involves the residue at position 93 playing the role of Nucleophile.
+Catalysis involves the residue at position 415 playing the role of .
+Catalysis involves the residue at position 467 playing the role of .
+Catalysis involves the residue at position 476 playing the role of .
+Catalysis involves the residue at position 84 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 197 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 293 playing the role of Proton acceptor.
+Catalysis involves the residue at position 571 playing the role of Proton donor.
+Catalysis involves the residue at position 49 playing the role of Proton donor.
+Catalysis involves the residue at position 1262 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1501 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1542 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 374 playing the role of .
+Catalysis involves the residue at position 27 playing the role of Nucleophile.
+Catalysis involves the residue at position 148 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 119 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 12 playing the role of Nucleophile.
+Catalysis involves the residue at position 97 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 64 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 275 playing the role of Proton donor.
+Catalysis involves the residue at position 681 playing the role of Proton donor.
+Catalysis involves the residue at position 363 playing the role of Charge relay system.
+Catalysis involves the residue at position 482 playing the role of Charge relay system.
+Catalysis involves the residue at position 331 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 359 playing the role of Proton acceptor.
+Catalysis involves the residue at position 356 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 668 playing the role of Proton donor.
+Catalysis involves the residue at position 112 playing the role of .
+Catalysis involves the residue at position 47 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 124 playing the role of Charge relay system.
+Catalysis involves the residue at position 153 playing the role of Charge relay system.
+Catalysis involves the residue at position 131 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 54 playing the role of Proton acceptor.
+Catalysis involves the residue at position 306 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 111 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 307 playing the role of Nucleophile.
+Catalysis involves the residue at position 260 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 275 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 824 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1181 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1209 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 294 playing the role of .
+Catalysis involves the residue at position 73 playing the role of Proton acceptor.
+Catalysis involves the residue at position 63 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 68 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 83 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 390 playing the role of Proton acceptor.
+Catalysis involves the residue at position 214 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 168 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 732 playing the role of Proton acceptor.
+Catalysis involves the residue at position 507 playing the role of Proton donor.
+Catalysis involves the residue at position 821 playing the role of Proton acceptor.
+Catalysis involves the residue at position 339 playing the role of .
+Catalysis involves the residue at position 391 playing the role of Nucleophile.
+Catalysis involves the residue at position 228 playing the role of Proton acceptor.
+Catalysis involves the residue at position 490 playing the role of Charge relay system.
+Catalysis involves the residue at position 544 playing the role of Charge relay system.
+Catalysis involves the residue at position 650 playing the role of Charge relay system.
+Catalysis involves the residue at position 514 playing the role of Proton acceptor.
+Catalysis involves the residue at position 24 playing the role of .
+Catalysis involves the residue at position 228 playing the role of .
+Catalysis involves the residue at position 265 playing the role of Proton acceptor.
+Catalysis involves the residue at position 129 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 167 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 250 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 64 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 463 playing the role of .
+Catalysis involves the residue at position 85 playing the role of Proton acceptor.
+Catalysis involves the residue at position 170 playing the role of Proton acceptor.
+Catalysis involves the residue at position 112 playing the role of Proton donor.
+Catalysis involves the residue at position 187 playing the role of Charge relay system.
+Catalysis involves the residue at position 61 playing the role of .
+Catalysis involves the residue at position 231 playing the role of Proton donor.
+Catalysis involves the residue at position 330 playing the role of .
+Catalysis involves the residue at position 851 playing the role of .
+Catalysis involves the residue at position 332 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 334 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 142 playing the role of Proton donor.
+Catalysis involves the residue at position 188 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 197 playing the role of Proton acceptor.
+Catalysis involves the residue at position 287 playing the role of Nucleophile.
+Catalysis involves the residue at position 143 playing the role of Charge relay system.
+Catalysis involves the residue at position 326 playing the role of Charge relay system.
+Catalysis involves the residue at position 117 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 313 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 322 playing the role of Proton acceptor.
+Catalysis involves the residue at position 95 playing the role of .
+Catalysis involves the residue at position 22 playing the role of .
+Catalysis involves the residue at position 144 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 284 playing the role of .
+Catalysis involves the residue at position 370 playing the role of Proton donor.
+Catalysis involves the residue at position 111 playing the role of Nucleophile.
+Catalysis involves the residue at position 209 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 49 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 56 playing the role of Proton donor.
+Catalysis involves the residue at position 322 playing the role of Proton donor.
+Catalysis involves the residue at position 142 playing the role of Proton acceptor.
+Catalysis involves the residue at position 72 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 203 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 33 playing the role of Proton donor.
+Catalysis involves the residue at position 402 playing the role of Nucleophile.
+Catalysis involves the residue at position 349 playing the role of Nucleophile.
+Catalysis involves the residue at position 1133 playing the role of Nucleophile.
+Catalysis involves the residue at position 1258 playing the role of .
+Catalysis involves the residue at position 1260 playing the role of .
+Catalysis involves the residue at position 221 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 222 playing the role of Charge relay system.
+Catalysis involves the residue at position 276 playing the role of Charge relay system.
+Catalysis involves the residue at position 372 playing the role of Charge relay system.
+Catalysis involves the residue at position 824 playing the role of .
+Catalysis involves the residue at position 195 playing the role of Proton acceptor.
+Catalysis involves the residue at position 93 playing the role of .
+Catalysis involves the residue at position 212 playing the role of Proton donor.
+Catalysis involves the residue at position 329 playing the role of Nucleophile.
+Catalysis involves the residue at position 123 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 753 playing the role of Proton acceptor.
+Catalysis involves the residue at position 307 playing the role of Proton acceptor.
+Catalysis involves the residue at position 233 playing the role of Proton donor.
+Catalysis involves the residue at position 40 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 263 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 255 playing the role of Nucleophile.
+Catalysis involves the residue at position 299 playing the role of Proton donor.
+Catalysis involves the residue at position 191 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 267 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 378 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 378 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 718 playing the role of .
+Catalysis involves the residue at position 66 playing the role of Proton donor.
+Catalysis involves the residue at position 722 playing the role of Proton acceptor.
+Catalysis involves the residue at position 172 playing the role of Proton donor.
+Catalysis involves the residue at position 316 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 139 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 353 playing the role of Proton acceptor.
+Catalysis involves the residue at position 224 playing the role of Nucleophile.
+Catalysis involves the residue at position 212 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1263 playing the role of .
+Catalysis involves the residue at position 1265 playing the role of .
+Catalysis involves the residue at position 67 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 81 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 237 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 250 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 349 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 135 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 163 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 295 playing the role of Charge relay system.
+Catalysis involves the residue at position 362 playing the role of Charge relay system.
+Catalysis involves the residue at position 558 playing the role of Charge relay system.
+Catalysis involves the residue at position 641 playing the role of Charge relay system.
+Catalysis involves the residue at position 673 playing the role of Charge relay system.
+Catalysis involves the residue at position 225 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 162 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 287 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 261 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 65 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 56 playing the role of Nucleophile.
+Catalysis involves the residue at position 185 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 379 playing the role of Charge relay system.
+Catalysis involves the residue at position 163 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 87 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 104 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 88 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 461 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 22 playing the role of Charge relay system.
+Catalysis involves the residue at position 251 playing the role of Charge relay system.
+Catalysis involves the residue at position 669 playing the role of .
+Catalysis involves the residue at position 143 playing the role of Proton acceptor.
+Catalysis involves the residue at position 103 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 43 playing the role of .
+Catalysis involves the residue at position 171 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 165 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 201 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 318 playing the role of Charge relay system.
+Catalysis involves the residue at position 111 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 67 playing the role of Proton donor.
+Catalysis involves the residue at position 248 playing the role of Nucleophile.
+Catalysis involves the residue at position 376 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 98 playing the role of Proton acceptor.
+Catalysis involves the residue at position 173 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 55 playing the role of Proton donor.
+Catalysis involves the residue at position 562 playing the role of Proton donor.
+Catalysis involves the residue at position 281 playing the role of Proton acceptor.
+Catalysis involves the residue at position 268 playing the role of Proton acceptor.
+Catalysis involves the residue at position 105 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 90 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 11 playing the role of Proton acceptor; for FBP phosphatase activity.
+Catalysis involves the residue at position 228 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 231 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.
+Catalysis involves the residue at position 525 playing the role of Proton acceptor.
+Catalysis involves the residue at position 111 playing the role of Charge relay system.
+Catalysis involves the residue at position 159 playing the role of Charge relay system.
+Catalysis involves the residue at position 354 playing the role of Proton donor.
+Catalysis involves the residue at position 769 playing the role of Charge relay system.
+Catalysis involves the residue at position 846 playing the role of Charge relay system.
+Catalysis involves the residue at position 879 playing the role of Charge relay system.
+Catalysis involves the residue at position 746 playing the role of Charge relay system.
+Catalysis involves the residue at position 965 playing the role of Nucleophile.
+Catalysis involves the residue at position 1023 playing the role of Charge relay system.
+Catalysis involves the residue at position 212 playing the role of Charge relay system.
+Catalysis involves the residue at position 386 playing the role of Charge relay system.
+Catalysis involves the residue at position 15 playing the role of Nucleophile.
+Catalysis involves the residue at position 63 playing the role of Proton acceptor.
+Catalysis involves the residue at position 189 playing the role of Charge relay system.
+Catalysis involves the residue at position 344 playing the role of Charge relay system.
+Catalysis involves the residue at position 116 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 178 playing the role of Proton donor.
+Catalysis involves the residue at position 196 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 221 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 27 playing the role of .
+Catalysis involves the residue at position 153 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 191 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 148 playing the role of Proton acceptor.
+Catalysis involves the residue at position 189 playing the role of .
+Catalysis involves the residue at position 32 playing the role of Nucleophile.
+Catalysis involves the residue at position 633 playing the role of Proton donor.
+Catalysis involves the residue at position 263 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 272 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 410 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 83 playing the role of Nucleophile.
+Catalysis involves the residue at position 287 playing the role of Proton donor.
+Catalysis involves the residue at position 185 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 95 playing the role of Proton acceptor.
+Catalysis involves the residue at position 320 playing the role of Proton acceptor.
+Catalysis involves the residue at position 348 playing the role of Proton donor.
+Catalysis involves the residue at position 689 playing the role of .
+Catalysis involves the residue at position 605 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 262 playing the role of .
+Catalysis involves the residue at position 557 playing the role of Proton donor.
+Catalysis involves the residue at position 240 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 382 playing the role of Proton donor.
+Catalysis involves the residue at position 98 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 234 playing the role of Nucleophile.
+Catalysis involves the residue at position 117 playing the role of Charge relay.
+Catalysis involves the residue at position 939 playing the role of Proton acceptor.
+Catalysis involves the residue at position 51 playing the role of .
+Catalysis involves the residue at position 104 playing the role of Proton donor; for formyltransferase activity.
+Catalysis involves the residue at position 434 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 619 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 487 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 388 playing the role of Proton acceptor.
+Catalysis involves the residue at position 360 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 291 playing the role of Charge relay system.
+Catalysis involves the residue at position 177 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 268 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 350 playing the role of .
+Catalysis involves the residue at position 106 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 44 playing the role of Charge relay system.
+Catalysis involves the residue at position 264 playing the role of Charge relay system.
+Catalysis involves the residue at position 449 playing the role of Charge relay system.
+Catalysis involves the residue at position 132 playing the role of Charge relay.
+Catalysis involves the residue at position 370 playing the role of .
+Catalysis involves the residue at position 14 playing the role of Proton donor.
+Catalysis involves the residue at position 262 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 99 playing the role of Proton donor.
+Catalysis involves the residue at position 174 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 258 playing the role of Nucleophile.
+Catalysis involves the residue at position 548 playing the role of .
+Catalysis involves the residue at position 254 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 273 playing the role of Proton donor.
+Catalysis involves the residue at position 123 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 373 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 221 playing the role of Proton donor.
+Catalysis involves the residue at position 442 playing the role of Proton acceptor.
+Catalysis involves the residue at position 188 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 491 playing the role of .
+Catalysis involves the residue at position 77 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 149 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 205 playing the role of .
+Catalysis involves the residue at position 515 playing the role of Proton acceptor.
+Catalysis involves the residue at position 205 playing the role of Proton acceptor.
+Catalysis involves the residue at position 182 playing the role of Proton acceptor.
+Catalysis involves the residue at position 424 playing the role of Proton donor.
+Catalysis involves the residue at position 452 playing the role of For 3-hydroxyacyl-CoA dehydrogenase activity.
+Catalysis involves the residue at position 42 playing the role of Nucleophile.
+Catalysis involves the residue at position 149 playing the role of Proton donor.
+Catalysis involves the residue at position 583 playing the role of Proton donor.
+Catalysis involves the residue at position 173 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 314 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 349 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 194 playing the role of Charge relay system.
+Catalysis involves the residue at position 271 playing the role of Charge relay system.
+Catalysis involves the residue at position 337 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 920 playing the role of Nucleophile.
+Catalysis involves the residue at position 537 playing the role of .
+Catalysis involves the residue at position 286 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 16 playing the role of .
+Catalysis involves the residue at position 181 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 45 playing the role of Proton acceptor; for glutaminase activity.
+Catalysis involves the residue at position 114 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 175 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 83 playing the role of Proton acceptor.
+Catalysis involves the residue at position 486 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1174 playing the role of Proton acceptor.
+Catalysis involves the residue at position 242 playing the role of Nucleophile.
+Catalysis involves the residue at position 136 playing the role of Proton donor.
+Catalysis involves the residue at position 154 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 96 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 157 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 228 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 705 playing the role of Proton donor.
+Catalysis involves the residue at position 266 playing the role of Proton donor.
+Catalysis involves the residue at position 389 playing the role of Nucleophile.
+Catalysis involves the residue at position 350 playing the role of Proton acceptor.
+Catalysis involves the residue at position 251 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 112 playing the role of For GATase activity.
+Catalysis involves the residue at position 198 playing the role of For GATase activity.
+Catalysis involves the residue at position 200 playing the role of For GATase activity.
+Catalysis involves the residue at position 317 playing the role of Nucleophile.
+Catalysis involves the residue at position 174 playing the role of Proton donor.
+Catalysis involves the residue at position 134 playing the role of Proton acceptor.
+Catalysis involves the residue at position 325 playing the role of .
+Catalysis involves the residue at position 94 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 420 playing the role of Nucleophile.
+Catalysis involves the residue at position 565 playing the role of Proton acceptor.
+Catalysis involves the residue at position 234 playing the role of Proton donor.
+Catalysis involves the residue at position 368 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 139 playing the role of Charge relay system.
+Catalysis involves the residue at position 211 playing the role of Charge relay system.
+Catalysis involves the residue at position 427 playing the role of Charge relay system.
+Catalysis involves the residue at position 44 playing the role of Proton acceptor; for glutaminase activity.
+Catalysis involves the residue at position 112 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 148 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 116 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 477 playing the role of Proton donor.
+Catalysis involves the residue at position 553 playing the role of Nucleophile.
+Catalysis involves the residue at position 89 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 146 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 252 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 252 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 91 playing the role of Nucleophile.
+Catalysis involves the residue at position 96 playing the role of Proton donor.
+Catalysis involves the residue at position 115 playing the role of Nucleophile.
+Catalysis involves the residue at position 235 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 182 playing the role of Nucleophile.
+Catalysis involves the residue at position 487 playing the role of Proton acceptor.
+Catalysis involves the residue at position 385 playing the role of Nucleophile.
+Catalysis involves the residue at position 349 playing the role of Proton acceptor.
+Catalysis involves the residue at position 358 playing the role of Proton donor.
+Catalysis involves the residue at position 1003 playing the role of Proton acceptor.
+Catalysis involves the residue at position 276 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 134 playing the role of Nucleophile.
+Catalysis involves the residue at position 239 playing the role of .
+Catalysis involves the residue at position 56 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 505 playing the role of .
+Catalysis involves the residue at position 159 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 197 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 179 playing the role of Proton donor.
+Catalysis involves the residue at position 583 playing the role of .
+Catalysis involves the residue at position 244 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 472 playing the role of Proton acceptor.
+Catalysis involves the residue at position 295 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 34 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 677 playing the role of Charge relay system.
+Catalysis involves the residue at position 727 playing the role of Charge relay system.
+Catalysis involves the residue at position 826 playing the role of Charge relay system.
+Catalysis involves the residue at position 672 playing the role of Proton donor.
+Catalysis involves the residue at position 503 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 507 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 48 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 281 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 273 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 177 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 249 playing the role of Nucleophile.
+Catalysis involves the residue at position 158 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 57 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 64 playing the role of Proton donor.
+Catalysis involves the residue at position 148 playing the role of Nucleophile.
+Catalysis involves the residue at position 225 playing the role of Charge relay system.
+Catalysis involves the residue at position 321 playing the role of Charge relay system.
+Catalysis involves the residue at position 388 playing the role of Charge relay system.
+Catalysis involves the residue at position 41 playing the role of Proton acceptor.
+Catalysis involves the residue at position 23 playing the role of .
+Catalysis involves the residue at position 41 playing the role of .
+Catalysis involves the residue at position 262 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 396 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 135 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 87 playing the role of Proton acceptor.
+Catalysis involves the residue at position 198 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 362 playing the role of .
+Catalysis involves the residue at position 520 playing the role of Nucleophile.
+Catalysis involves the residue at position 653 playing the role of Proton acceptor.
+Catalysis involves the residue at position 268 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 283 playing the role of Charge relay system.
+Catalysis involves the residue at position 381 playing the role of Charge relay system.
+Catalysis involves the residue at position 356 playing the role of Charge relay system.
+Catalysis involves the residue at position 91 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 263 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 393 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 259 playing the role of .
+Catalysis involves the residue at position 347 playing the role of Nucleophile.
+Catalysis involves the residue at position 95 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 520 playing the role of Proton acceptor.
+Catalysis involves the residue at position 123 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 211 playing the role of Nucleophile.
+Catalysis involves the residue at position 454 playing the role of Proton donor.
+Catalysis involves the residue at position 332 playing the role of .
+Catalysis involves the residue at position 110 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 247 playing the role of Proton donor.
+Catalysis involves the residue at position 397 playing the role of Proton acceptor 1.
+Catalysis involves the residue at position 526 playing the role of Proton donor 1.
+Catalysis involves the residue at position 995 playing the role of Proton acceptor 2.
+Catalysis involves the residue at position 1124 playing the role of Proton donor 2.
+Catalysis involves the residue at position 60 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 261 playing the role of Nucleophile.
+Catalysis involves the residue at position 346 playing the role of .
+Catalysis involves the residue at position 348 playing the role of .
+Catalysis involves the residue at position 142 playing the role of Charge relay system.
+Catalysis involves the residue at position 197 playing the role of Charge relay system.
+Catalysis involves the residue at position 519 playing the role of Charge relay system.
+Catalysis involves the residue at position 270 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 68 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 174 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 91 playing the role of .
+Catalysis involves the residue at position 64 playing the role of .
+Catalysis involves the residue at position 330 playing the role of Nucleophile.
+Catalysis involves the residue at position 436 playing the role of .
+Catalysis involves the residue at position 86 playing the role of Proton donor.
+Catalysis involves the residue at position 397 playing the role of Proton donor.
+Catalysis involves the residue at position 25 playing the role of Proton donor.
+Catalysis involves the residue at position 326 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 509 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 225 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 397 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 298 playing the role of .
+Catalysis involves the residue at position 451 playing the role of .
+Catalysis involves the residue at position 16 playing the role of Nucleophile.
+Catalysis involves the residue at position 416 playing the role of .
+Catalysis involves the residue at position 468 playing the role of .
+Catalysis involves the residue at position 477 playing the role of .
+Catalysis involves the residue at position 629 playing the role of Proton donor.
+Catalysis involves the residue at position 151 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 133 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 170 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 172 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 331 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 371 playing the role of Nucleophile.
+Catalysis involves the residue at position 81 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 441 playing the role of Proton donor.
+Catalysis involves the residue at position 104 playing the role of Proton acceptor.
+Catalysis involves the residue at position 366 playing the role of Proton acceptor.
+Catalysis involves the residue at position 214 playing the role of .
+Catalysis involves the residue at position 482 playing the role of .
+Catalysis involves the residue at position 24 playing the role of Nucleophile.
+Catalysis involves the residue at position 292 playing the role of .
+Catalysis involves the residue at position 457 playing the role of Charge relay system.
+Catalysis involves the residue at position 460 playing the role of .
+Catalysis involves the residue at position 150 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 173 playing the role of .
+Catalysis involves the residue at position 452 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 333 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 117 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 122 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 145 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 55 playing the role of .
+Catalysis involves the residue at position 124 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 151 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 384 playing the role of Proton acceptor.
+Catalysis involves the residue at position 154 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 175 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 42 playing the role of .
+Catalysis involves the residue at position 171 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 311 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 345 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 341 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 316 playing the role of Nucleophile.
+Catalysis involves the residue at position 238 playing the role of Proton donor.
+Catalysis involves the residue at position 113 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 118 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 141 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 334 playing the role of .
+Catalysis involves the residue at position 132 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 6 playing the role of .
+Catalysis involves the residue at position 227 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 150 playing the role of Nucleophile.
+Catalysis involves the residue at position 132 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 123 playing the role of Nucleophile.
+Catalysis involves the residue at position 214 playing the role of Proton donor.
+Catalysis involves the residue at position 96 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 86 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 458 playing the role of .
+Catalysis involves the residue at position 125 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 409 playing the role of .
+Catalysis involves the residue at position 124 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 124 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 433 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 304 playing the role of Nucleophile.
+Catalysis involves the residue at position 642 playing the role of Proton acceptor.
+Catalysis involves the residue at position 64 playing the role of Nucleophile.
+Catalysis involves the residue at position 420 playing the role of Proton acceptor.
+Catalysis involves the residue at position 465 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 660 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 85 playing the role of .
+Catalysis involves the residue at position 163 playing the role of Nucleophile.
+Catalysis involves the residue at position 325 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 76 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 81 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 96 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 496 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 66 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 236 playing the role of Proton acceptor.
+Catalysis involves the residue at position 61 playing the role of Charge relay system.
+Catalysis involves the residue at position 105 playing the role of Charge relay system.
+Catalysis involves the residue at position 534 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 312 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 359 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 743 playing the role of Charge relay system.
+Catalysis involves the residue at position 820 playing the role of Charge relay system.
+Catalysis involves the residue at position 853 playing the role of Charge relay system.
+Catalysis involves the residue at position 75 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 131 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 283 playing the role of .
+Catalysis involves the residue at position 407 playing the role of Charge relay system.
+Catalysis involves the residue at position 463 playing the role of Charge relay system.
+Catalysis involves the residue at position 569 playing the role of Charge relay system.
+Catalysis involves the residue at position 398 playing the role of Proton acceptor.
+Catalysis involves the residue at position 484 playing the role of Proton acceptor.
+Catalysis involves the residue at position 461 playing the role of Proton acceptor.
+Catalysis involves the residue at position 360 playing the role of Proton donor.
+Catalysis involves the residue at position 751 playing the role of Charge relay system.
+Catalysis involves the residue at position 828 playing the role of Charge relay system.
+Catalysis involves the residue at position 861 playing the role of Charge relay system.
+Catalysis involves the residue at position 339 playing the role of Charge relay system.
+Catalysis involves the residue at position 459 playing the role of .
+Catalysis involves the residue at position 8 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 161 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 202 playing the role of Proton acceptor.
+Catalysis involves the residue at position 211 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 356 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 257 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 240 playing the role of Charge relay system.
+Catalysis involves the residue at position 414 playing the role of Charge relay system.
+Catalysis involves the residue at position 362 playing the role of Nucleophile.
+Catalysis involves the residue at position 39 playing the role of Proton acceptor.
+Catalysis involves the residue at position 451 playing the role of For 3-hydroxyacyl-CoA dehydrogenase activity.
+Catalysis involves the residue at position 139 playing the role of Proton donor.
+Catalysis involves the residue at position 180 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 213 playing the role of Proton acceptor.
+Catalysis involves the residue at position 13 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 248 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 106 playing the role of Proton donor; for formyltransferase activity.
+Catalysis involves the residue at position 437 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 621 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 146 playing the role of Proton acceptor.
+Catalysis involves the residue at position 220 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 131 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 532 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 216 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 180 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 153 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 446 playing the role of .
+Catalysis involves the residue at position 342 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 65 playing the role of Proton donor.
+Catalysis involves the residue at position 333 playing the role of Charge relay system.
+Catalysis involves the residue at position 167 playing the role of Nucleophile.
+Catalysis involves the residue at position 409 playing the role of Nucleophile.
+Catalysis involves the residue at position 462 playing the role of Proton donor.
+Catalysis involves the residue at position 177 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 184 playing the role of Proton donor.
+Catalysis involves the residue at position 406 playing the role of Proton acceptor.
+Catalysis involves the residue at position 492 playing the role of Proton acceptor.
+Catalysis involves the residue at position 265 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 96 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 94 playing the role of Proton donor.
+Catalysis involves the residue at position 224 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 440 playing the role of Nucleophile.
+Catalysis involves the residue at position 493 playing the role of Proton donor.
+Catalysis involves the residue at position 203 playing the role of Nucleophile.
+Catalysis involves the residue at position 521 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 466 playing the role of .
+Catalysis involves the residue at position 527 playing the role of .
+Catalysis involves the residue at position 177 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 184 playing the role of Charge relay system.
+Catalysis involves the residue at position 258 playing the role of Charge relay system.
+Catalysis involves the residue at position 178 playing the role of Nucleophile.
+Catalysis involves the residue at position 421 playing the role of Proton acceptor.
+Catalysis involves the residue at position 252 playing the role of Proton donor.
+Catalysis involves the residue at position 166 playing the role of Charge relay system.
+Catalysis involves the residue at position 207 playing the role of Charge relay system.
+Catalysis involves the residue at position 62 playing the role of Nucleophile.
+Catalysis involves the residue at position 336 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 93 playing the role of For GATase activity.
+Catalysis involves the residue at position 185 playing the role of For GATase activity.
+Catalysis involves the residue at position 187 playing the role of For GATase activity.
+Catalysis involves the residue at position 682 playing the role of .
+Catalysis involves the residue at position 126 playing the role of Nucleophile.
+Catalysis involves the residue at position 46 playing the role of Proton donor.
+Catalysis involves the residue at position 54 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 122 playing the role of Charge relay system.
+Catalysis involves the residue at position 133 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 107 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 308 playing the role of Proton donor.
+Catalysis involves the residue at position 207 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 99 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 478 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 674 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 81 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 125 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 297 playing the role of Charge relay system.
+Catalysis involves the residue at position 176 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 615 playing the role of Proton acceptor.
+Catalysis involves the residue at position 298 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 387 playing the role of Charge relay system.
+Catalysis involves the residue at position 432 playing the role of Charge relay system.
+Catalysis involves the residue at position 695 playing the role of Charge relay system.
+Catalysis involves the residue at position 300 playing the role of .
+Catalysis involves the residue at position 569 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 704 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 747 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1361 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1550 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 91 playing the role of Charge relay system.
+Catalysis involves the residue at position 190 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 86 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 242 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 283 playing the role of Proton donor.
+Catalysis involves the residue at position 100 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 432 playing the role of Proton donor.
+Catalysis involves the residue at position 149 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 153 playing the role of Proton donor.
+Catalysis involves the residue at position 230 playing the role of .
+Catalysis involves the residue at position 327 playing the role of Nucleophile.
+Catalysis involves the residue at position 457 playing the role of Proton acceptor.
+Catalysis involves the residue at position 378 playing the role of Proton acceptor.
+Catalysis involves the residue at position 693 playing the role of Proton donor.
+Catalysis involves the residue at position 59 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 344 playing the role of Nucleophile.
+Catalysis involves the residue at position 449 playing the role of .
+Catalysis involves the residue at position 102 playing the role of Charge relay system.
+Catalysis involves the residue at position 12 playing the role of Proton donor.
+Catalysis involves the residue at position 347 playing the role of Proton acceptor.
+Catalysis involves the residue at position 54 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 339 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 101 playing the role of Proton acceptor.
+Catalysis involves the residue at position 113 playing the role of Proton donor.
+Catalysis involves the residue at position 297 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 256 playing the role of Proton donor.
+Catalysis involves the residue at position 119 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 184 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 274 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 488 playing the role of Proton donor.
+Catalysis involves the residue at position 578 playing the role of .
+Catalysis involves the residue at position 399 playing the role of Nucleophile.
+Catalysis involves the residue at position 323 playing the role of .
+Catalysis involves the residue at position 133 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 48 playing the role of Proton acceptor.
+Catalysis involves the residue at position 315 playing the role of Nucleophile.
+Catalysis involves the residue at position 470 playing the role of Proton acceptor.
+Catalysis involves the residue at position 245 playing the role of Nucleophile.
+Catalysis involves the residue at position 360 playing the role of .
+Catalysis involves the residue at position 250 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 407 playing the role of Nucleophile.
+Catalysis involves the residue at position 193 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 602 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 224 playing the role of Charge relay system.
+Catalysis involves the residue at position 264 playing the role of Proton acceptor.
+Catalysis involves the residue at position 394 playing the role of Proton donor.
+Catalysis involves the residue at position 322 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 271 playing the role of .
+Catalysis involves the residue at position 422 playing the role of Nucleophile.
+Catalysis involves the residue at position 10 playing the role of Proton donor.
+Catalysis involves the residue at position 142 playing the role of Nucleophile.
+Catalysis involves the residue at position 423 playing the role of Proton acceptor.
+Catalysis involves the residue at position 436 playing the role of Charge relay system.
+Catalysis involves the residue at position 458 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 185 playing the role of Nucleophile.
+Catalysis involves the residue at position 205 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 253 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1194 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 340 playing the role of .
+Catalysis involves the residue at position 260 playing the role of Proton donor.
+Catalysis involves the residue at position 23 playing the role of Nucleophile.
+Catalysis involves the residue at position 83 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 432 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 145 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 251 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 251 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 335 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 553 playing the role of .
+Catalysis involves the residue at position 775 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 250 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 110 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 195 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 122 playing the role of Charge relay.
+Catalysis involves the residue at position 158 playing the role of Nucleophile.
+Catalysis involves the residue at position 368 playing the role of Proton donor.
+Catalysis involves the residue at position 21 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 82 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 264 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 390 playing the role of Charge relay system.
+Catalysis involves the residue at position 418 playing the role of Charge relay system.
+Catalysis involves the residue at position 184 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 249 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 659 playing the role of .
+Catalysis involves the residue at position 666 playing the role of .
+Catalysis involves the residue at position 155 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 417 playing the role of .
+Catalysis involves the residue at position 421 playing the role of .
+Catalysis involves the residue at position 534 playing the role of Charge relay system.
+Catalysis involves the residue at position 619 playing the role of Charge relay system.
+Catalysis involves the residue at position 472 playing the role of .
+Catalysis involves the residue at position 534 playing the role of .
+Catalysis involves the residue at position 182 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 129 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 202 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 367 playing the role of .
+Catalysis involves the residue at position 126 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 17 playing the role of Proton donor.
+Catalysis involves the residue at position 201 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 768 playing the role of Charge relay system.
+Catalysis involves the residue at position 845 playing the role of Charge relay system.
+Catalysis involves the residue at position 878 playing the role of Charge relay system.
+Catalysis involves the residue at position 337 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 339 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 1138 playing the role of Nucleophile.
+Catalysis involves the residue at position 75 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 345 playing the role of Proton acceptor.
+Catalysis involves the residue at position 636 playing the role of Proton donor.
+Catalysis involves the residue at position 240 playing the role of Proton acceptor.
+Catalysis involves the residue at position 75 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 441 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 86 playing the role of Proton acceptor.
+Catalysis involves the residue at position 184 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 219 playing the role of Proton donor.
+Catalysis involves the residue at position 174 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 355 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 348 playing the role of Proton acceptor.
+Catalysis involves the residue at position 466 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 532 playing the role of Proton acceptor.
+Catalysis involves the residue at position 197 playing the role of Nucleophile.
+Catalysis involves the residue at position 152 playing the role of Proton donor.
+Catalysis involves the residue at position 765 playing the role of .
+Catalysis involves the residue at position 917 playing the role of .
+Catalysis involves the residue at position 1030 playing the role of .
+Catalysis involves the residue at position 178 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 308 playing the role of Charge relay system.
+Catalysis involves the residue at position 443 playing the role of Proton acceptor.
+Catalysis involves the residue at position 249 playing the role of Charge relay system.
+Catalysis involves the residue at position 294 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 681 playing the role of Proton acceptor.
+Catalysis involves the residue at position 130 playing the role of Proton acceptor.
+Catalysis involves the residue at position 222 playing the role of Proton donor.
+Catalysis involves the residue at position 331 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 290 playing the role of Nucleophile.
+Catalysis involves the residue at position 181 playing the role of Charge relay system.
+Catalysis involves the residue at position 77 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 168 playing the role of For GATase activity.
+Catalysis involves the residue at position 859 playing the role of Proton acceptor.
+Catalysis involves the residue at position 380 playing the role of Charge relay system.
+Catalysis involves the residue at position 262 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1232 playing the role of Proton acceptor.
+Catalysis involves the residue at position 292 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 601 playing the role of Proton acceptor.
+Catalysis involves the residue at position 881 playing the role of Proton donor.
+Catalysis involves the residue at position 803 playing the role of Proton acceptor.
+Catalysis involves the residue at position 117 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 260 playing the role of Nucleophile.
+Catalysis involves the residue at position 130 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 127 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 765 playing the role of Charge relay system.
+Catalysis involves the residue at position 842 playing the role of Charge relay system.
+Catalysis involves the residue at position 875 playing the role of Charge relay system.
+Catalysis involves the residue at position 391 playing the role of .
+Catalysis involves the residue at position 146 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 374 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 94 playing the role of Nucleophile.
+Catalysis involves the residue at position 694 playing the role of Proton donor.
+Catalysis involves the residue at position 184 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 118 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 74 playing the role of Charge relay system.
+Catalysis involves the residue at position 149 playing the role of Charge relay system.
+Catalysis involves the residue at position 173 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 325 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 327 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 216 playing the role of Nucleophile.
+Catalysis involves the residue at position 375 playing the role of Proton acceptor.
+Catalysis involves the residue at position 412 playing the role of Proton donor.
+Catalysis involves the residue at position 465 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 357 playing the role of Proton acceptor.
+Catalysis involves the residue at position 216 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 27 playing the role of Proton acceptor.
+Catalysis involves the residue at position 355 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 387 playing the role of Nucleophile.
+Catalysis involves the residue at position 180 playing the role of Charge relay system.
+Catalysis involves the residue at position 378 playing the role of Charge relay system.
+Catalysis involves the residue at position 78 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1230 playing the role of Proton acceptor.
+Catalysis involves the residue at position 693 playing the role of .
+Catalysis involves the residue at position 736 playing the role of .
+Catalysis involves the residue at position 406 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 137 playing the role of For ring-opening step.
+Catalysis involves the residue at position 139 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 144 playing the role of For ring-opening step.
+Catalysis involves the residue at position 355 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 725 playing the role of .
+Catalysis involves the residue at position 332 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 676 playing the role of .
+Catalysis involves the residue at position 719 playing the role of .
+Catalysis involves the residue at position 531 playing the role of .
+Catalysis involves the residue at position 199 playing the role of Nucleophile.
+Catalysis involves the residue at position 329 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 214 playing the role of Proton acceptor.
+Catalysis involves the residue at position 220 playing the role of Nucleophile.
+Catalysis involves the residue at position 326 playing the role of Proton donor.
+Catalysis involves the residue at position 326 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 11 playing the role of Charge relay system.
+Catalysis involves the residue at position 248 playing the role of Charge relay system.
+Catalysis involves the residue at position 215 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 95 playing the role of Proton donor.
+Catalysis involves the residue at position 249 playing the role of .
+Catalysis involves the residue at position 272 playing the role of .
+Catalysis involves the residue at position 281 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 112 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 137 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 276 playing the role of Proton acceptor.
+Catalysis involves the residue at position 31 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 307 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 403 playing the role of Proton acceptor.
+Catalysis involves the residue at position 353 playing the role of Proton donor.
+Catalysis involves the residue at position 513 playing the role of .
+Catalysis involves the residue at position 231 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 247 playing the role of Proton acceptor.
+Catalysis involves the residue at position 206 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 122 playing the role of Nucleophile.
+Catalysis involves the residue at position 289 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 449 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 478 playing the role of Nucleophile.
+Catalysis involves the residue at position 481 playing the role of .
+Catalysis involves the residue at position 1375 playing the role of Nucleophile.
+Catalysis involves the residue at position 1378 playing the role of .
+Catalysis involves the residue at position 117 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 173 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 260 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 260 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 270 playing the role of Proton acceptor.
+Catalysis involves the residue at position 169 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 570 playing the role of .
+Catalysis involves the residue at position 650 playing the role of Proton donor.
+Catalysis involves the residue at position 235 playing the role of Nucleophile.
+Catalysis involves the residue at position 339 playing the role of Nucleophile.
+Catalysis involves the residue at position 145 playing the role of Nucleophile.
+Catalysis involves the residue at position 307 playing the role of .
+Catalysis involves the residue at position 232 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 213 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 213 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 435 playing the role of Proton donor.
+Catalysis involves the residue at position 381 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 347 playing the role of Proton donor.
+Catalysis involves the residue at position 84 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 337 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 145 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 229 playing the role of Proton acceptor.
+Catalysis involves the residue at position 97 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 310 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 190 playing the role of Nucleophile.
+Catalysis involves the residue at position 186 playing the role of Charge relay system.
+Catalysis involves the residue at position 562 playing the role of Proton acceptor.
+Catalysis involves the residue at position 428 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 408 playing the role of Nucleophile.
+Catalysis involves the residue at position 600 playing the role of Charge relay system.
+Catalysis involves the residue at position 639 playing the role of Charge relay system.
+Catalysis involves the residue at position 59 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 178 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 30 playing the role of For protease activity.
+Catalysis involves the residue at position 4 playing the role of .
+Catalysis involves the residue at position 40 playing the role of Nucleophile.
+Catalysis involves the residue at position 182 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 473 playing the role of Proton donor.
+Catalysis involves the residue at position 414 playing the role of Nucleophile; for NAALADase activity.
+Catalysis involves the residue at position 618 playing the role of Charge relay system.
+Catalysis involves the residue at position 656 playing the role of Charge relay system.
+Catalysis involves the residue at position 679 playing the role of Charge relay system.
+Catalysis involves the residue at position 258 playing the role of Proton donor.
+Catalysis involves the residue at position 201 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 311 playing the role of Proton acceptor.
+Catalysis involves the residue at position 164 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 168 playing the role of Proton donor.
+Catalysis involves the residue at position 10 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 88 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 42 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 256 playing the role of Nucleophile.
+Catalysis involves the residue at position 452 playing the role of Proton donor.
+Catalysis involves the residue at position 772 playing the role of Proton acceptor.
+Catalysis involves the residue at position 706 playing the role of .
+Catalysis involves the residue at position 228 playing the role of Nucleophile.
+Catalysis involves the residue at position 548 playing the role of Proton acceptor.
+Catalysis involves the residue at position 96 playing the role of Charge relay system.
+Catalysis involves the residue at position 146 playing the role of Charge relay system.
+Catalysis involves the residue at position 241 playing the role of Charge relay system.
+Catalysis involves the residue at position 456 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 207 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 39 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 16 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate; for relaxase activity.
+Catalysis involves the residue at position 17 playing the role of Relaxase.
+Catalysis involves the residue at position 229 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 61 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 66 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 27 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 374 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 58 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 406 playing the role of Proton donor.
+Catalysis involves the residue at position 427 playing the role of Nucleophile.
+Catalysis involves the residue at position 274 playing the role of Nucleophile.
+Catalysis involves the residue at position 165 playing the role of Nucleophile.
+Catalysis involves the residue at position 470 playing the role of .
+Catalysis involves the residue at position 56 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 265 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 423 playing the role of Proton donor.
+Catalysis involves the residue at position 352 playing the role of Proton donor.
+Catalysis involves the residue at position 510 playing the role of Proton acceptor.
+Catalysis involves the residue at position 4 playing the role of Proton acceptor.
+Catalysis involves the residue at position 32 playing the role of Proton donor.
+Catalysis involves the residue at position 301 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 400 playing the role of Nucleophile.
+Catalysis involves the residue at position 453 playing the role of Proton donor.
+Catalysis involves the residue at position 333 playing the role of Proton donor.
+Catalysis involves the residue at position 473 playing the role of .
+Catalysis involves the residue at position 222 playing the role of .
+Catalysis involves the residue at position 241 playing the role of Proton donor.
+Catalysis involves the residue at position 696 playing the role of Charge relay system.
+Catalysis involves the residue at position 731 playing the role of Charge relay system.
+Catalysis involves the residue at position 273 playing the role of Nucleophile.
+Catalysis involves the residue at position 445 playing the role of Proton acceptor.
+Catalysis involves the residue at position 451 playing the role of Proton donor.
+Catalysis involves the residue at position 326 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 210 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 263 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 337 playing the role of Nucleophile.
+Catalysis involves the residue at position 439 playing the role of .
+Catalysis involves the residue at position 433 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 341 playing the role of .
+Catalysis involves the residue at position 440 playing the role of Proton acceptor.
+Catalysis involves the residue at position 188 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 195 playing the role of Proton donor.
+Catalysis involves the residue at position 312 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 187 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 194 playing the role of Proton donor.
+Catalysis involves the residue at position 344 playing the role of Proton acceptor.
+Catalysis involves the residue at position 218 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 234 playing the role of Charge relay system.
+Catalysis involves the residue at position 302 playing the role of Charge relay system.
+Catalysis involves the residue at position 50 playing the role of Charge relay system.
+Catalysis involves the residue at position 89 playing the role of Charge relay system.
+Catalysis involves the residue at position 114 playing the role of Charge relay system.
+Catalysis involves the residue at position 148 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 259 playing the role of Nucleophile.
+Catalysis involves the residue at position 14 playing the role of Nucleophile.
+Catalysis involves the residue at position 384 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 248 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 215 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 155 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 159 playing the role of Proton donor.
+Catalysis involves the residue at position 121 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 126 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 149 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 650 playing the role of Proton acceptor.
+Catalysis involves the residue at position 80 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 197 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 69 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 74 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 89 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 21 playing the role of Nucleophile.
+Catalysis involves the residue at position 88 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 107 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 133 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 389 playing the role of Proton donor.
+Catalysis involves the residue at position 942 playing the role of Proton acceptor.
+Catalysis involves the residue at position 599 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 502 playing the role of Charge relay system.
+Catalysis involves the residue at position 654 playing the role of Charge relay system.
+Catalysis involves the residue at position 130 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 747 playing the role of .
+Catalysis involves the residue at position 790 playing the role of .
+Catalysis involves the residue at position 546 playing the role of Proton acceptor.
+Catalysis involves the residue at position 196 playing the role of Acyl-thioester intermediate; for beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 367 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 641 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 947 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1115 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 25 playing the role of Nucleophile.
+Catalysis involves the residue at position 27 playing the role of Proton donor.
+Catalysis involves the residue at position 1548 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1839 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 226 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 353 playing the role of Charge relay system.
+Catalysis involves the residue at position 466 playing the role of Charge relay system.
+Catalysis involves the residue at position 343 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 846 playing the role of Proton acceptor.
+Catalysis involves the residue at position 20 playing the role of Nucleophile.
+Catalysis involves the residue at position 68 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 455 playing the role of .
+Catalysis involves the residue at position 252 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 80 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 135 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 297 playing the role of Proton donor.
+Catalysis involves the residue at position 314 playing the role of Proton donor.
+Catalysis involves the residue at position 130 playing the role of Schiff-base intermediate with KHG or pyruvate.
+Catalysis involves the residue at position 390 playing the role of Proton donor.
+Catalysis involves the residue at position 393 playing the role of Proton acceptor.
+Catalysis involves the residue at position 378 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 103 playing the role of Proton donor.
+Catalysis involves the residue at position 242 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 754 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 83 playing the role of Charge relay system.
+Catalysis involves the residue at position 310 playing the role of Proton acceptor.
+Catalysis involves the residue at position 398 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 502 playing the role of .
+Catalysis involves the residue at position 512 playing the role of Proton acceptor.
+Catalysis involves the residue at position 258 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 820 playing the role of Proton acceptor.
+Catalysis involves the residue at position 232 playing the role of .
+Catalysis involves the residue at position 279 playing the role of Proton donor.
+Catalysis involves the residue at position 367 playing the role of Proton donor.
+Catalysis involves the residue at position 342 playing the role of .
+Catalysis involves the residue at position 344 playing the role of .
+Catalysis involves the residue at position 16 playing the role of Proton acceptor.
+Catalysis involves the residue at position 113 playing the role of Charge relay.
+Catalysis involves the residue at position 11 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 199 playing the role of Proton acceptor.
+Catalysis involves the residue at position 385 playing the role of Charge relay system.
+Catalysis involves the residue at position 416 playing the role of S-acetylcysteine intermediate.
+Catalysis involves the residue at position 417 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 106 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 215 playing the role of 1.
+Catalysis involves the residue at position 610 playing the role of 2.
+Catalysis involves the residue at position 620 playing the role of Charge relay system.
+Catalysis involves the residue at position 51 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 245 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 465 playing the role of Proton acceptor.
+Catalysis involves the residue at position 280 playing the role of Proton donor.
+Catalysis involves the residue at position 435 playing the role of .
+Catalysis involves the residue at position 339 playing the role of Proton donor.
+Catalysis involves the residue at position 203 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 495 playing the role of Charge relay system.
+Catalysis involves the residue at position 68 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 1135 playing the role of Nucleophile.
+Catalysis involves the residue at position 1262 playing the role of .
+Catalysis involves the residue at position 653 playing the role of Proton donor.
+Catalysis involves the residue at position 293 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 233 playing the role of .
+Catalysis involves the residue at position 121 playing the role of Proton acceptor.
+Catalysis involves the residue at position 178 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 271 playing the role of For protease activity.
+Catalysis involves the residue at position 711 playing the role of Charge relay system.
+Catalysis involves the residue at position 805 playing the role of Charge relay system.
+Catalysis involves the residue at position 208 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 166 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 227 playing the role of Charge relay system.
+Catalysis involves the residue at position 599 playing the role of Proton donor.
+Catalysis involves the residue at position 704 playing the role of Nucleophile.
+Catalysis involves the residue at position 298 playing the role of Proton acceptor.
+Catalysis involves the residue at position 119 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 208 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 926 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 167 playing the role of Proton donor.
+Catalysis involves the residue at position 543 playing the role of Proton acceptor.
+Catalysis involves the residue at position 231 playing the role of Nucleophile.
+Catalysis involves the residue at position 373 playing the role of Proton donor.
+Catalysis involves the residue at position 9 playing the role of Proton acceptor.
+Catalysis involves the residue at position 383 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 336 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 140 playing the role of Charge relay system.
+Catalysis involves the residue at position 164 playing the role of Charge relay system.
+Catalysis involves the residue at position 144 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 270 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 285 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 856 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1224 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1252 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 121 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 61 playing the role of Nucleophile.
+Catalysis involves the residue at position 390 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 534 playing the role of Proton acceptor.
+Catalysis involves the residue at position 449 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 458 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 141 playing the role of Proton donor.
+Catalysis involves the residue at position 312 playing the role of Nucleophile.
+Catalysis involves the residue at position 1305 playing the role of Nucleophile.
+Catalysis involves the residue at position 1423 playing the role of Proton acceptor.
+Catalysis involves the residue at position 89 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 112 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 56 playing the role of Charge relay system.
+Catalysis involves the residue at position 101 playing the role of Charge relay system.
+Catalysis involves the residue at position 209 playing the role of Nucleophile.
+Catalysis involves the residue at position 306 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 454 playing the role of Proton acceptor.
+Catalysis involves the residue at position 470 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 26 playing the role of Nucleophile.
+Catalysis involves the residue at position 762 playing the role of Charge relay system.
+Catalysis involves the residue at position 870 playing the role of Charge relay system.
+Catalysis involves the residue at position 476 playing the role of Proton acceptor.
+Catalysis involves the residue at position 73 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 852 playing the role of Proton acceptor.
+Catalysis involves the residue at position 142 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 220 playing the role of Proton acceptor.
+Catalysis involves the residue at position 688 playing the role of .
+Catalysis involves the residue at position 731 playing the role of .
+Catalysis involves the residue at position 445 playing the role of Charge relay system.
+Catalysis involves the residue at position 596 playing the role of Charge relay system.
+Catalysis involves the residue at position 396 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 98 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 90 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 268 playing the role of Proton donor.
+Catalysis involves the residue at position 77 playing the role of Proton donor.
+Catalysis involves the residue at position 239 playing the role of Charge relay system.
+Catalysis involves the residue at position 269 playing the role of Charge relay system.
+Catalysis involves the residue at position 613 playing the role of .
+Catalysis involves the residue at position 676 playing the role of Proton donor.
+Catalysis involves the residue at position 396 playing the role of Proton donor.
+Catalysis involves the residue at position 133 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 310 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 148 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 186 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 1161 playing the role of Proton donor.
+Catalysis involves the residue at position 21 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 126 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 163 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 192 playing the role of Nucleophile.
+Catalysis involves the residue at position 116 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 149 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 717 playing the role of .
+Catalysis involves the residue at position 208 playing the role of Nucleophile.
+Catalysis involves the residue at position 100 playing the role of Electrophile.
+Catalysis involves the residue at position 234 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 247 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 294 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 401 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 477 playing the role of Proton acceptor.
+Catalysis involves the residue at position 264 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 279 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 832 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1188 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1216 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 525 playing the role of Proton donor.
+Catalysis involves the residue at position 109 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1388 playing the role of .
+Catalysis involves the residue at position 1433 playing the role of .
+Catalysis involves the residue at position 383 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 178 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 128 playing the role of Charge relay system.
+Catalysis involves the residue at position 152 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 253 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 253 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 272 playing the role of Proton acceptor.
+Catalysis involves the residue at position 390 playing the role of Nucleophile.
+Catalysis involves the residue at position 350 playing the role of Nucleophile.
+Catalysis involves the residue at position 494 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 299 playing the role of Proton acceptor.
+Catalysis involves the residue at position 157 playing the role of .
+Catalysis involves the residue at position 393 playing the role of Nucleophile.
+Catalysis involves the residue at position 55 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 171 playing the role of Proton donors.
+Catalysis involves the residue at position 64 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 126 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 289 playing the role of Nucleophile.
+Catalysis involves the residue at position 223 playing the role of Proton acceptor.
+Catalysis involves the residue at position 424 playing the role of Nucleophile.
+Catalysis involves the residue at position 321 playing the role of .
+Catalysis involves the residue at position 214 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 352 playing the role of Nucleophile.
+Catalysis involves the residue at position 909 playing the role of Proton acceptor.
+Catalysis involves the residue at position 414 playing the role of .
+Catalysis involves the residue at position 475 playing the role of .
+Catalysis involves the residue at position 133 playing the role of Nucleophile.
+Catalysis involves the residue at position 26 playing the role of Proton acceptor.
+Catalysis involves the residue at position 146 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 302 playing the role of Proton donor.
+Catalysis involves the residue at position 400 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 10 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 209 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 42 playing the role of Proton acceptor; for glutaminase activity.
+Catalysis involves the residue at position 117 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 153 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 63 playing the role of Charge relay system.
+Catalysis involves the residue at position 184 playing the role of Nucleophile.
+Catalysis involves the residue at position 442 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 774 playing the role of Proton donor.
+Catalysis involves the residue at position 633 playing the role of Proton acceptor.
+Catalysis involves the residue at position 422 playing the role of .
+Catalysis involves the residue at position 432 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 311 playing the role of For class II diterpene cyclase activity.
+Catalysis involves the residue at position 649 playing the role of For class I diterpene synthase activity.
+Catalysis involves the residue at position 275 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 13 playing the role of Proton donor.
+Catalysis involves the residue at position 104 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 112 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 117 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 140 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 634 playing the role of Proton acceptor.
+Catalysis involves the residue at position 214 playing the role of Charge relay system.
+Catalysis involves the residue at position 346 playing the role of Charge relay system.
+Catalysis involves the residue at position 126 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 292 playing the role of Nucleophile.
+Catalysis involves the residue at position 691 playing the role of .
+Catalysis involves the residue at position 721 playing the role of .
+Catalysis involves the residue at position 221 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 69 playing the role of Nucleophile.
+Catalysis involves the residue at position 85 playing the role of Redox-active.
+Catalysis involves the residue at position 88 playing the role of Redox-active.
+Catalysis involves the residue at position 349 playing the role of Charge relay system.
+Catalysis involves the residue at position 284 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 861 playing the role of Proton acceptor.
+Catalysis involves the residue at position 430 playing the role of Proton donor.
+Catalysis involves the residue at position 480 playing the role of .
+Catalysis involves the residue at position 603 playing the role of .
+Catalysis involves the residue at position 93 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 570 playing the role of Proton acceptor.
+Catalysis involves the residue at position 43 playing the role of Redox-active.
+Catalysis involves the residue at position 158 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 196 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 341 playing the role of Charge relay system.
+Catalysis involves the residue at position 412 playing the role of .
+Catalysis involves the residue at position 54 playing the role of Proton donor.
+Catalysis involves the residue at position 123 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 345 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 123 playing the role of Proton donor.
+Catalysis involves the residue at position 189 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 305 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 401 playing the role of Proton acceptor.
+Catalysis involves the residue at position 242 playing the role of .
+Catalysis involves the residue at position 459 playing the role of Proton acceptor.
+Catalysis involves the residue at position 213 playing the role of Proton donor.
+Catalysis involves the residue at position 98 playing the role of Electrophile.
+Catalysis involves the residue at position 211 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 140 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 171 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 394 playing the role of .
+Catalysis involves the residue at position 51 playing the role of Proton donor.
+Catalysis involves the residue at position 1030 playing the role of Proton acceptor.
+Catalysis involves the residue at position 378 playing the role of Nucleophile.
+Catalysis involves the residue at position 381 playing the role of Nucleophile.
+Catalysis involves the residue at position 406 playing the role of Nucleophile.
+Catalysis involves the residue at position 20 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 356 playing the role of Proton acceptor.
+Catalysis involves the residue at position 598 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 593 playing the role of .
+Catalysis involves the residue at position 92 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 195 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 46 playing the role of Nucleophile.
+Catalysis involves the residue at position 53 playing the role of Schiff-base intermediate with pyridoxal 5'-phosphate.
+Catalysis involves the residue at position 105 playing the role of Proton donor.
+Catalysis involves the residue at position 79 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 210 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 348 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 463 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 463 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 207 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 342 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 382 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 652 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 1196 playing the role of Nucleophile; for thioesterase activity.
+Catalysis involves the residue at position 1316 playing the role of Proton acceptor; for thioesterase activity.
+Catalysis involves the residue at position 1024 playing the role of Proton acceptor.
+Catalysis involves the residue at position 358 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 167 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 348 playing the role of Nucleophile.
+Catalysis involves the residue at position 677 playing the role of .
+Catalysis involves the residue at position 752 playing the role of .
+Catalysis involves the residue at position 909 playing the role of .
+Catalysis involves the residue at position 18 playing the role of Nucleophile.
+Catalysis involves the residue at position 386 playing the role of Proton acceptor.
+Catalysis involves the residue at position 604 playing the role of Proton acceptor.
+Catalysis involves the residue at position 259 playing the role of Proton donor.
+Catalysis involves the residue at position 399 playing the role of Proton donor.
+Catalysis involves the residue at position 233 playing the role of Nucleophile.
+Catalysis involves the residue at position 269 playing the role of Proton donor.
+Catalysis involves the residue at position 447 playing the role of .
+Catalysis involves the residue at position 80 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 70 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 102 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 72 playing the role of Charge relay system.
+Catalysis involves the residue at position 219 playing the role of Charge relay system.
+Catalysis involves the residue at position 523 playing the role of Proton acceptor.
+Catalysis involves the residue at position 371 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 129 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 387 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 334 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 238 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 893 playing the role of Proton acceptor.
+Catalysis involves the residue at position 205 playing the role of Charge relay system.
+Catalysis involves the residue at position 56 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 575 playing the role of Charge relay system.
+Catalysis involves the residue at position 707 playing the role of Charge relay system.
+Catalysis involves the residue at position 783 playing the role of Charge relay system.
+Catalysis involves the residue at position 882 playing the role of Proton donor.
+Catalysis involves the residue at position 171 playing the role of Proton donor.
+Catalysis involves the residue at position 606 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 455 playing the role of Nucleophile.
+Catalysis involves the residue at position 761 playing the role of Proton acceptor.
+Catalysis involves the residue at position 72 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 147 playing the role of Nucleophile.
+Catalysis involves the residue at position 416 playing the role of Nucleophile.
+Catalysis involves the residue at position 482 playing the role of Proton donor.
+Catalysis involves the residue at position 490 playing the role of Proton donor.
+Catalysis involves the residue at position 78 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 92 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 256 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 178 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 313 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 353 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 625 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 305 playing the role of Nucleophile.
+Catalysis involves the residue at position 149 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 187 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 467 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 321 playing the role of Proton acceptor.
+Catalysis involves the residue at position 422 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 424 playing the role of Proton acceptor.
+Catalysis involves the residue at position 401 playing the role of .
+Catalysis involves the residue at position 236 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 373 playing the role of Charge relay system.
+Catalysis involves the residue at position 310 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 144 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 167 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 294 playing the role of Nucleophile.
+Catalysis involves the residue at position 163 playing the role of Proton donor; for a subset of substrates.
+Catalysis involves the residue at position 377 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 19 playing the role of Proton acceptor.
+Catalysis involves the residue at position 216 playing the role of Charge relay system.
+Catalysis involves the residue at position 165 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 283 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 298 playing the role of Charge relay system.
+Catalysis involves the residue at position 391 playing the role of Charge relay system.
+Catalysis involves the residue at position 416 playing the role of Charge relay system.
+Catalysis involves the residue at position 750 playing the role of Proton acceptor.
+Catalysis involves the residue at position 126 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 709 playing the role of Proton donor.
+Catalysis involves the residue at position 327 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 329 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 51 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 272 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 66 playing the role of Nucleophile.
+Catalysis involves the residue at position 228 playing the role of Proton donor.
+Catalysis involves the residue at position 478 playing the role of Proton donor.
+Catalysis involves the residue at position 481 playing the role of Proton acceptor.
+Catalysis involves the residue at position 322 playing the role of Nucleophile.
+Catalysis involves the residue at position 29 playing the role of .
+Catalysis involves the residue at position 86 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 100 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 263 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 389 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 128 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 55 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 448 playing the role of Proton acceptor.
+Catalysis involves the residue at position 169 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 297 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 332 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 579 playing the role of Proton acceptor.
+Catalysis involves the residue at position 826 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 871 playing the role of Proton acceptor.
+Catalysis involves the residue at position 93 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 87 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 183 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 131 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 238 playing the role of .
+Catalysis involves the residue at position 196 playing the role of Charge relay system.
+Catalysis involves the residue at position 370 playing the role of Charge relay system.
+Catalysis involves the residue at position 797 playing the role of Proton acceptor.
+Catalysis involves the residue at position 133 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 108 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 785 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 920 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 960 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 576 playing the role of Proton acceptor.
+Catalysis involves the residue at position 222 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 354 playing the role of Charge relay system.
+Catalysis involves the residue at position 836 playing the role of Proton acceptor.
+Catalysis involves the residue at position 554 playing the role of Charge relay system.
+Catalysis involves the residue at position 680 playing the role of Charge relay system.
+Catalysis involves the residue at position 342 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 485 playing the role of Proton acceptor.
+Catalysis involves the residue at position 394 playing the role of Charge relay system.
+Catalysis involves the residue at position 204 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 453 playing the role of Nucleophile.
+Catalysis involves the residue at position 456 playing the role of Nucleophile.
+Catalysis involves the residue at position 375 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 157 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 161 playing the role of Proton donor.
+Catalysis involves the residue at position 945 playing the role of Proton acceptor.
+Catalysis involves the residue at position 136 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 346 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 344 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 93 playing the role of Charge relay system.
+Catalysis involves the residue at position 261 playing the role of Proton acceptor.
+Catalysis involves the residue at position 455 playing the role of Proton acceptor.
+Catalysis involves the residue at position 81 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 1197 playing the role of .
+Catalysis involves the residue at position 177 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 601 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 813 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 495 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 946 playing the role of .
+Catalysis involves the residue at position 989 playing the role of .
+Catalysis involves the residue at position 326 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 241 playing the role of Nucleophile.
+Catalysis involves the residue at position 1992 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 232 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 1029 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 467 playing the role of Proton donor.
+Catalysis involves the residue at position 269 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 563 playing the role of Proton acceptor.
+Catalysis involves the residue at position 311 playing the role of Charge relay system.
+Catalysis involves the residue at position 842 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1157 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 562 playing the role of .
+Catalysis involves the residue at position 727 playing the role of .
+Catalysis involves the residue at position 462 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 738 playing the role of .
+Catalysis involves the residue at position 781 playing the role of .
+Catalysis involves the residue at position 562 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 697 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 740 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1350 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1539 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 280 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 181 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 319 playing the role of Nucleophile.
+Catalysis involves the residue at position 402 playing the role of .
+Catalysis involves the residue at position 142 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 202 playing the role of .
+Catalysis involves the residue at position 118 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 444 playing the role of .
+Catalysis involves the residue at position 393 playing the role of .
+Catalysis involves the residue at position 395 playing the role of .
+Catalysis involves the residue at position 139 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 258 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 555 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 690 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 729 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1326 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1508 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1955 playing the role of For methyltransferase activity.
+Catalysis involves the residue at position 2067 playing the role of For methyltransferase activity.
+Catalysis involves the residue at position 2093 playing the role of For methyltransferase activity.
+Catalysis involves the residue at position 466 playing the role of Proton acceptor.
+Catalysis involves the residue at position 112 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 394 playing the role of Proton acceptor.
+Catalysis involves the residue at position 150 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 329 playing the role of Proton donor.
+Catalysis involves the residue at position 355 playing the role of Nucleophile.
+Catalysis involves the residue at position 40 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 231 playing the role of Nucleophile or transition state stabilizer.
+Catalysis involves the residue at position 134 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 359 playing the role of Charge relay system.
+Catalysis involves the residue at position 101 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 172 playing the role of Nucleophile.
+Catalysis involves the residue at position 224 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 225 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 327 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 150 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 205 playing the role of Nucleophile.
+Catalysis involves the residue at position 114 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 708 playing the role of .
+Catalysis involves the residue at position 751 playing the role of .
+Catalysis involves the residue at position 282 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 600 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 276 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 303 playing the role of Proton acceptor.
+Catalysis involves the residue at position 960 playing the role of Nucleophile.
+Catalysis involves the residue at position 1080 playing the role of Proton acceptor.
+Catalysis involves the residue at position 119 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 122 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 414 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 109 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 350 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 601 playing the role of .
+Catalysis involves the residue at position 644 playing the role of Proton acceptor.
+Catalysis involves the residue at position 224 playing the role of Proton donor.
+Catalysis involves the residue at position 88 playing the role of Electrophile.
+Catalysis involves the residue at position 357 playing the role of Proton donor.
+Catalysis involves the residue at position 369 playing the role of Charge relay system.
+Catalysis involves the residue at position 72 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 474 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 684 playing the role of .
+Catalysis involves the residue at position 86 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 142 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 226 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 226 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 115 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 118 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 155 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 236 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 383 playing the role of Proton donor.
+Catalysis involves the residue at position 189 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 502 playing the role of Proton donor.
+Catalysis involves the residue at position 105 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 428 playing the role of Proton acceptor.
+Catalysis involves the residue at position 185 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 35 playing the role of Nucleophile.
+Catalysis involves the residue at position 152 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 66 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 377 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 142 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 34 playing the role of .
+Catalysis involves the residue at position 192 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 825 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1182 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1211 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 100 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 109 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 217 playing the role of .
+Catalysis involves the residue at position 304 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 88 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 498 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 502 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 290 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 365 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 112 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 845 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1189 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1218 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 529 playing the role of Proton acceptor.
+Catalysis involves the residue at position 709 playing the role of Proton acceptor.
+Catalysis involves the residue at position 372 playing the role of Proton acceptor.
+Catalysis involves the residue at position 46 playing the role of Charge relay system.
+Catalysis involves the residue at position 90 playing the role of Charge relay system.
+Catalysis involves the residue at position 251 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 443 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 144 playing the role of Nucleophile.
+Catalysis involves the residue at position 203 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 328 playing the role of Nucleophile.
+Catalysis involves the residue at position 318 playing the role of Proton donor.
+Catalysis involves the residue at position 128 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 166 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 788 playing the role of Proton acceptor.
+Catalysis involves the residue at position 359 playing the role of Proton donor.
+Catalysis involves the residue at position 746 playing the role of Proton acceptor.
+Catalysis involves the residue at position 279 playing the role of Nucleophile.
+Catalysis involves the residue at position 81 playing the role of Charge relay system.
+Catalysis involves the residue at position 156 playing the role of Charge relay system.
+Catalysis involves the residue at position 180 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 140 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 221 playing the role of Proton acceptor.
+Catalysis involves the residue at position 371 playing the role of Proton acceptor.
+Catalysis involves the residue at position 212 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 175 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 900 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 246 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 236 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 539 playing the role of Nucleophile.
+Catalysis involves the residue at position 127 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 395 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 1566 playing the role of Nucleophile.
+Catalysis involves the residue at position 1879 playing the role of Proton acceptor.
+Catalysis involves the residue at position 558 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 121 playing the role of Nucleophile.
+Catalysis involves the residue at position 88 playing the role of Proton acceptor; for pyrophosphatase activity.
+Catalysis involves the residue at position 265 playing the role of Charge relay system.
+Catalysis involves the residue at position 147 playing the role of Charge relay system.
+Catalysis involves the residue at position 155 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 496 playing the role of Proton acceptor.
+Catalysis involves the residue at position 52 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 412 playing the role of Nucleophile.
+Catalysis involves the residue at position 942 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 138 playing the role of Charge relay system.
+Catalysis involves the residue at position 444 playing the role of Nucleophile.
+Catalysis involves the residue at position 125 playing the role of Charge relay system.
+Catalysis involves the residue at position 6 playing the role of Nucleophile.
+Catalysis involves the residue at position 315 playing the role of Proton donor.
+Catalysis involves the residue at position 151 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 52 playing the role of Proton donor.
+Catalysis involves the residue at position 318 playing the role of Nucleophile.
+Catalysis involves the residue at position 28 playing the role of Charge relay system.
+Catalysis involves the residue at position 103 playing the role of Charge relay system.
+Catalysis involves the residue at position 127 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 366 playing the role of .
+Catalysis involves the residue at position 338 playing the role of Proton donor.
+Catalysis involves the residue at position 9 playing the role of Proton donor.
+Catalysis involves the residue at position 54 playing the role of Nucleophile; methyl group acceptor from methylphosphotriester.
+Catalysis involves the residue at position 120 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 229 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 605 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 387 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1079 playing the role of .
+Catalysis involves the residue at position 1245 playing the role of .
+Catalysis involves the residue at position 323 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 963 playing the role of Proton acceptor.
+Catalysis involves the residue at position 69 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 115 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 104 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 206 playing the role of Nucleophile.
+Catalysis involves the residue at position 524 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 69 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 92 playing the role of Proton donor.
+Catalysis involves the residue at position 229 playing the role of Nucleophile.
+Catalysis involves the residue at position 549 playing the role of Proton acceptor.
+Catalysis involves the residue at position 357 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 258 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 327 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 451 playing the role of Charge relay system.
+Catalysis involves the residue at position 479 playing the role of Charge relay system.
+Catalysis involves the residue at position 49 playing the role of Charge relay system.
+Catalysis involves the residue at position 1053 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 60 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 264 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 700 playing the role of Proton donor.
+Catalysis involves the residue at position 89 playing the role of For GATase activity.
+Catalysis involves the residue at position 176 playing the role of For GATase activity.
+Catalysis involves the residue at position 178 playing the role of For GATase activity.
+Catalysis involves the residue at position 39 playing the role of .
+Catalysis involves the residue at position 242 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 70 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 433 playing the role of .
+Catalysis involves the residue at position 154 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 392 playing the role of Nucleophile.
+Catalysis involves the residue at position 45 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 407 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 697 playing the role of .
+Catalysis involves the residue at position 260 playing the role of Proton acceptor.
+Catalysis involves the residue at position 44 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 269 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 539 playing the role of Proton acceptor.
+Catalysis involves the residue at position 241 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 414 playing the role of Proton acceptor.
+Catalysis involves the residue at position 654 playing the role of .
+Catalysis involves the residue at position 961 playing the role of Nucleophile.
+Catalysis involves the residue at position 1081 playing the role of Proton acceptor.
+Catalysis involves the residue at position 120 playing the role of Nucleophile.
+Catalysis involves the residue at position 324 playing the role of Charge relay system.
+Catalysis involves the residue at position 335 playing the role of Charge relay system.
+Catalysis involves the residue at position 71 playing the role of Nucleophile.
+Catalysis involves the residue at position 97 playing the role of Proton donor.
+Catalysis involves the residue at position 118 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 225 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 584 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 177 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 316 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 354 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 633 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 956 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1121 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 53 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 257 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 481 playing the role of N6-AMP-lysine intermediate; for ligase activity.
+Catalysis involves the residue at position 250 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 173 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 52 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 753 playing the role of .
+Catalysis involves the residue at position 480 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 101 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 309 playing the role of Proton acceptor.
+Catalysis involves the residue at position 143 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 240 playing the role of Nucleophile.
+Catalysis involves the residue at position 293 playing the role of Charge relay system.
+Catalysis involves the residue at position 570 playing the role of Proton donor.
+Catalysis involves the residue at position 599 playing the role of .
+Catalysis involves the residue at position 63 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 129 playing the role of For ring-opening step.
+Catalysis involves the residue at position 131 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 707 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1001 playing the role of Charge relay system.
+Catalysis involves the residue at position 1077 playing the role of Charge relay system.
+Catalysis involves the residue at position 1175 playing the role of Proton donor.
+Catalysis involves the residue at position 319 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 116 playing the role of Schiff-base intermediate with acetoacetate.
+Catalysis involves the residue at position 255 playing the role of Charge relay system.
+Catalysis involves the residue at position 301 playing the role of Charge relay system.
+Catalysis involves the residue at position 400 playing the role of Charge relay system.
+Catalysis involves the residue at position 291 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 95 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 124 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 165 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 199 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 80 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 57 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 374 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 398 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 161 playing the role of Nucleophile.
+Catalysis involves the residue at position 239 playing the role of Nucleophile.
+Catalysis involves the residue at position 282 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 441 playing the role of .
+Catalysis involves the residue at position 308 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 492 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 456 playing the role of Proton acceptor.
+Catalysis involves the residue at position 252 playing the role of Charge relay system.
+Catalysis involves the residue at position 397 playing the role of Charge relay system.
+Catalysis involves the residue at position 159 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 199 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 70 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 172 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 299 playing the role of Charge relay system.
+Catalysis involves the residue at position 84 playing the role of Charge relay system.
+Catalysis involves the residue at position 183 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 419 playing the role of Proton donor.
+Catalysis involves the residue at position 483 playing the role of Proton acceptor.
+Catalysis involves the residue at position 439 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 435 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 180 playing the role of Nucleophile.
+Catalysis involves the residue at position 456 playing the role of Proton donor.
+Catalysis involves the residue at position 488 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 398 playing the role of Charge relay system.
+Catalysis involves the residue at position 238 playing the role of Nucleophile.
+Catalysis involves the residue at position 235 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 192 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 485 playing the role of Proton donor.
+Catalysis involves the residue at position 281 playing the role of Proton donor.
+Catalysis involves the residue at position 640 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 421 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 128 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 388 playing the role of Nucleophile.
+Catalysis involves the residue at position 118 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 259 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 377 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 344 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 350 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 446 playing the role of Proton acceptor.
+Catalysis involves the residue at position 275 playing the role of Charge relay system.
+Catalysis involves the residue at position 376 playing the role of Charge relay system.
+Catalysis involves the residue at position 462 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 12 playing the role of Nucleophile; cysteine thioarsenate intermediate.
+Catalysis involves the residue at position 398 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 94 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 253 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 437 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 191 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 404 playing the role of Charge relay system.
+Catalysis involves the residue at position 444 playing the role of Charge relay system.
+Catalysis involves the residue at position 845 playing the role of Proton acceptor.
+Catalysis involves the residue at position 494 playing the role of Proton donor.
+Catalysis involves the residue at position 497 playing the role of Proton acceptor.
+Catalysis involves the residue at position 256 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 379 playing the role of .
+Catalysis involves the residue at position 438 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 332 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 75 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 415 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 391 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 92 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 149 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 751 playing the role of Proton acceptor.
+Catalysis involves the residue at position 232 playing the role of Nucleophile.
+Catalysis involves the residue at position 364 playing the role of Charge relay system.
+Catalysis involves the residue at position 1036 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 263 playing the role of Proton donor.
+Catalysis involves the residue at position 994 playing the role of .
+Catalysis involves the residue at position 1024 playing the role of .
+Catalysis involves the residue at position 49 playing the role of Redox-active.
+Catalysis involves the residue at position 226 playing the role of Proton donor.
+Catalysis involves the residue at position 210 playing the role of Proton acceptor.
+Catalysis involves the residue at position 174 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 84 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 134 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 416 playing the role of Proton acceptor.
+Catalysis involves the residue at position 224 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 965 playing the role of Proton acceptor.
+Catalysis involves the residue at position 429 playing the role of Proton donor.
+Catalysis involves the residue at position 237 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 127 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 220 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 458 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 753 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 308 playing the role of Nucleophile.
+Catalysis involves the residue at position 376 playing the role of Proton acceptor.
+Catalysis involves the residue at position 378 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 183 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 291 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 857 playing the role of .
+Catalysis involves the residue at position 989 playing the role of Nucleophile.
+Catalysis involves the residue at position 14 playing the role of Pros-phosphohistidine intermediate; alternate.
+Catalysis involves the residue at position 304 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 266 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 319 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 137 playing the role of Proton donor.
+Catalysis involves the residue at position 217 playing the role of Nucleophile.
+Catalysis involves the residue at position 338 playing the role of Nucleophile.
+Catalysis involves the residue at position 749 playing the role of Proton acceptor.
+Catalysis involves the residue at position 302 playing the role of Nucleophile.
+Catalysis involves the residue at position 840 playing the role of Proton donor.
+Catalysis involves the residue at position 941 playing the role of Nucleophile.
+Catalysis involves the residue at position 600 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 103 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 166 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 198 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 539 playing the role of Proton donor.
+Catalysis involves the residue at position 105 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 702 playing the role of .
+Catalysis involves the residue at position 745 playing the role of .
+Catalysis involves the residue at position 351 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 42 playing the role of Redox-active.
+Catalysis involves the residue at position 93 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 159 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 518 playing the role of Nucleophile.
+Catalysis involves the residue at position 248 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 63 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 14 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 854 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 163 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 173 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 152 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 255 playing the role of Proton donor.
+Catalysis involves the residue at position 189 playing the role of Nucleophile.
+Catalysis involves the residue at position 749 playing the role of Charge relay system.
+Catalysis involves the residue at position 827 playing the role of Charge relay system.
+Catalysis involves the residue at position 859 playing the role of Charge relay system.
+Catalysis involves the residue at position 12 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 56 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 243 playing the role of Proton acceptor.
+Catalysis involves the residue at position 391 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1317 playing the role of Proton acceptor.
+Catalysis involves the residue at position 496 playing the role of .
+Catalysis involves the residue at position 86 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 478 playing the role of .
+Catalysis involves the residue at position 886 playing the role of .
+Catalysis involves the residue at position 380 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 401 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 413 playing the role of Nucleophile.
+Catalysis involves the residue at position 466 playing the role of Proton donor.
+Catalysis involves the residue at position 443 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 499 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 587 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 587 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 386 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 189 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 365 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 386 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 122 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 214 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 241 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 385 playing the role of For shikimate dehydrogenase activity.
+Catalysis involves the residue at position 423 playing the role of For shikimate dehydrogenase activity.
+Catalysis involves the residue at position 483 playing the role of Nucleophile.
+Catalysis involves the residue at position 97 playing the role of Nucleophile.
+Catalysis involves the residue at position 312 playing the role of Proton donor.
+Catalysis involves the residue at position 62 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 67 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 267 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 437 playing the role of .
+Catalysis involves the residue at position 271 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 351 playing the role of Charge relay system.
+Catalysis involves the residue at position 382 playing the role of Charge relay system.
+Catalysis involves the residue at position 178 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 95 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 1083 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1378 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 61 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 310 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 577 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 712 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 755 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1400 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1602 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 331 playing the role of Proton acceptor.
+Catalysis involves the residue at position 237 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 141 playing the role of Charge relay system.
+Catalysis involves the residue at position 250 playing the role of Charge relay system.
+Catalysis involves the residue at position 385 playing the role of .
+Catalysis involves the residue at position 107 playing the role of Charge relay system.
+Catalysis involves the residue at position 277 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 559 playing the role of Charge relay system.
+Catalysis involves the residue at position 645 playing the role of Charge relay system.
+Catalysis involves the residue at position 690 playing the role of Charge relay system.
+Catalysis involves the residue at position 143 playing the role of Proton donor.
+Catalysis involves the residue at position 759 playing the role of .
+Catalysis involves the residue at position 791 playing the role of .
+Catalysis involves the residue at position 924 playing the role of .
+Catalysis involves the residue at position 254 playing the role of Nucleophile.
+Catalysis involves the residue at position 61 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 193 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 108 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 211 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1185 playing the role of Proton acceptor.
+Catalysis involves the residue at position 327 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 386 playing the role of Nucleophile.
+Catalysis involves the residue at position 737 playing the role of .
+Catalysis involves the residue at position 786 playing the role of .
+Catalysis involves the residue at position 795 playing the role of .
+Catalysis involves the residue at position 320 playing the role of Charge relay system.
+Catalysis involves the residue at position 350 playing the role of Charge relay system.
+Catalysis involves the residue at position 435 playing the role of Charge relay system.
+Catalysis involves the residue at position 876 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 237 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 465 playing the role of Charge relay system.
+Catalysis involves the residue at position 301 playing the role of Nucleophile.
+Catalysis involves the residue at position 399 playing the role of For GATase activity.
+Catalysis involves the residue at position 526 playing the role of For GATase activity.
+Catalysis involves the residue at position 528 playing the role of For GATase activity.
+Catalysis involves the residue at position 611 playing the role of Proton acceptor.
+Catalysis involves the residue at position 180 playing the role of Proton donor.
+Catalysis involves the residue at position 184 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 54 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 157 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 348 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 598 playing the role of Proton acceptor.
+Catalysis involves the residue at position 578 playing the role of Proton acceptor.
+Catalysis involves the residue at position 100 playing the role of Charge relay system.
+Catalysis involves the residue at position 204 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 569 playing the role of Proton acceptor.
+Catalysis involves the residue at position 174 playing the role of Charge relay system.
+Catalysis involves the residue at position 952 playing the role of Proton acceptor.
+Catalysis involves the residue at position 177 playing the role of Nucleophile.
+Catalysis involves the residue at position 311 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 316 playing the role of Proton acceptor.
+Catalysis involves the residue at position 156 playing the role of Nucleophile.
+Catalysis involves the residue at position 312 playing the role of Charge relay system.
+Catalysis involves the residue at position 752 playing the role of Proton donor.
+Catalysis involves the residue at position 551 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 687 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 726 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1323 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1500 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1999 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2148 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 1040 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 166 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 382 playing the role of Proton acceptor.
+Catalysis involves the residue at position 156 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 100 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1186 playing the role of Proton acceptor.
+Catalysis involves the residue at position 115 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 244 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1229 playing the role of .
+Catalysis involves the residue at position 387 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 171 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 134 playing the role of Charge relay system.
+Catalysis involves the residue at position 405 playing the role of S-acetylcysteine intermediate.
+Catalysis involves the residue at position 406 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 181 playing the role of Proton donor.
+Catalysis involves the residue at position 376 playing the role of Nucleophile.
+Catalysis involves the residue at position 135 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 16 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 383 playing the role of Nucleophile.
+Catalysis involves the residue at position 342 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 217 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 24 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 111 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 387 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 460 playing the role of Charge relay system.
+Catalysis involves the residue at position 564 playing the role of Charge relay system.
+Catalysis involves the residue at position 261 playing the role of Proton donor.
+Catalysis involves the residue at position 370 playing the role of Nucleophile.
+Catalysis involves the residue at position 124 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 1271 playing the role of Proton acceptor; for thioesterase activity.
+Catalysis involves the residue at position 219 playing the role of Nucleophile.
+Catalysis involves the residue at position 353 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 255 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 404 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1250 playing the role of Nucleophile.
+Catalysis involves the residue at position 1368 playing the role of Proton acceptor.
+Catalysis involves the residue at position 340 playing the role of Nucleophile.
+Catalysis involves the residue at position 1934 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 35 playing the role of Proton donor.
+Catalysis involves the residue at position 108 playing the role of Charge relay system.
+Catalysis involves the residue at position 707 playing the role of Proton donor.
+Catalysis involves the residue at position 257 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 185 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 68 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 631 playing the role of Proton acceptor.
+Catalysis involves the residue at position 990 playing the role of .
+Catalysis involves the residue at position 1033 playing the role of .
+Catalysis involves the residue at position 842 playing the role of Nucleophile.
+Catalysis involves the residue at position 871 playing the role of Proton donor.
+Catalysis involves the residue at position 257 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 272 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 820 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1172 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1200 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 160 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 603 playing the role of For molybdenum cofactor biosynthesis protein C activity.
+Catalysis involves the residue at position 795 playing the role of Proton acceptor.
+Catalysis involves the residue at position 988 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 237 playing the role of Nucleophile.
+Catalysis involves the residue at position 135 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 587 playing the role of Charge relay system.
+Catalysis involves the residue at position 675 playing the role of Charge relay system.
+Catalysis involves the residue at position 120 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 286 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 967 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 490 playing the role of .
+Catalysis involves the residue at position 29 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 129 playing the role of Charge relay.
+Catalysis involves the residue at position 196 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 195 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 420 playing the role of .
+Catalysis involves the residue at position 412 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 812 playing the role of Proton acceptor.
+Catalysis involves the residue at position 764 playing the role of .
+Catalysis involves the residue at position 214 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 285 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 127 playing the role of Charge relay system.
+Catalysis involves the residue at position 1585 playing the role of Proton acceptor.
+Catalysis involves the residue at position 282 playing the role of Proton donor.
+Catalysis involves the residue at position 254 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 367 playing the role of Proton acceptor.
+Catalysis involves the residue at position 336 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 357 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 209 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 237 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 225 playing the role of Proton donor.
+Catalysis involves the residue at position 749 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 341 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 212 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 267 playing the role of Proton donor.
+Catalysis involves the residue at position 138 playing the role of Nucleophile.
+Catalysis involves the residue at position 274 playing the role of Proton donor.
+Catalysis involves the residue at position 142 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 194 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 330 playing the role of Charge relay system.
+Catalysis involves the residue at position 361 playing the role of Charge relay system.
+Catalysis involves the residue at position 208 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 501 playing the role of Proton donor.
+Catalysis involves the residue at position 102 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 70 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 75 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 90 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 39 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 55 playing the role of Schiff-base intermediate with pyridoxal 5'-phosphate.
+Catalysis involves the residue at position 453 playing the role of .
+Catalysis involves the residue at position 339 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 404 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 591 playing the role of .
+Catalysis involves the residue at position 151 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 127 playing the role of Nucleophile.
+Catalysis involves the residue at position 374 playing the role of Proton acceptor; for phosphotransferase activity.
+Catalysis involves the residue at position 408 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 111 playing the role of Proton donor.
+Catalysis involves the residue at position 202 playing the role of Charge relay system.
+Catalysis involves the residue at position 242 playing the role of Charge relay system.
+Catalysis involves the residue at position 419 playing the role of Charge relay system.
+Catalysis involves the residue at position 323 playing the role of Proton donor.
+Catalysis involves the residue at position 376 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 147 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 58 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 461 playing the role of For protease activity; shared with dimeric partner.
+Catalysis involves the residue at position 538 playing the role of Nucleophile.
+Catalysis involves the residue at position 604 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 624 playing the role of Proton acceptor.
+Catalysis involves the residue at position 47 playing the role of Charge relay system.
+Catalysis involves the residue at position 148 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 718 playing the role of Proton acceptor.
+Catalysis involves the residue at position 843 playing the role of Proton acceptor.
+Catalysis involves the residue at position 871 playing the role of .
+Catalysis involves the residue at position 280 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 475 playing the role of Proton donor.
+Catalysis involves the residue at position 365 playing the role of Proton donor.
+Catalysis involves the residue at position 264 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 164 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 304 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 341 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 182 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 317 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 357 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 962 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1160 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 322 playing the role of Charge relay system.
+Catalysis involves the residue at position 124 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 415 playing the role of Proton acceptor.
+Catalysis involves the residue at position 89 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 188 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 511 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 64 playing the role of Nucleophile or proton acceptor.
+Catalysis involves the residue at position 1333 playing the role of Proton acceptor.
+Catalysis involves the residue at position 469 playing the role of .
+Catalysis involves the residue at position 185 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 273 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 723 playing the role of Proton acceptor.
+Catalysis involves the residue at position 542 playing the role of .
+Catalysis involves the residue at position 9 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 465 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 145 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 658 playing the role of Charge relay system.
+Catalysis involves the residue at position 691 playing the role of Charge relay system.
+Catalysis involves the residue at position 8 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 573 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 156 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 691 playing the role of Proton acceptor.
+Catalysis involves the residue at position 833 playing the role of .
+Catalysis involves the residue at position 386 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 715 playing the role of .
+Catalysis involves the residue at position 758 playing the role of .
+Catalysis involves the residue at position 472 playing the role of Charge relay system.
+Catalysis involves the residue at position 524 playing the role of Charge relay system.
+Catalysis involves the residue at position 120 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 540 playing the role of Proton donor.
+Catalysis involves the residue at position 413 playing the role of Proton donor.
+Catalysis involves the residue at position 39 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 265 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 243 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 735 playing the role of Proton acceptor.
+Catalysis involves the residue at position 111 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 116 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 139 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 338 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1305 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1583 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 232 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 1013 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1344 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 172 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 508 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 471 playing the role of Proton acceptor.
+Catalysis involves the residue at position 85 playing the role of Electrophile.
+Catalysis involves the residue at position 117 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 224 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 426 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 450 playing the role of Nucleophile.
+Catalysis involves the residue at position 380 playing the role of Proton donor.
+Catalysis involves the residue at position 453 playing the role of Proton acceptor.
+Catalysis involves the residue at position 107 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 425 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 161 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 293 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 183 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 403 playing the role of .
+Catalysis involves the residue at position 1188 playing the role of Proton acceptor.
+Catalysis involves the residue at position 26 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 81 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 330 playing the role of Proton acceptor.
+Catalysis involves the residue at position 321 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 130 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 208 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 338 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 258 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 440 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 625 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 468 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 884 playing the role of Nucleophile.
+Catalysis involves the residue at position 838 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 87 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 215 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 81 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 299 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 194 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 522 playing the role of .
+Catalysis involves the residue at position 535 playing the role of Proton acceptor.
+Catalysis involves the residue at position 258 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 188 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 1205 playing the role of Proton acceptor.
+Catalysis involves the residue at position 214 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 51 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 898 playing the role of .
+Catalysis involves the residue at position 277 playing the role of Charge relay system.
+Catalysis involves the residue at position 218 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 400 playing the role of Proton donor.
+Catalysis involves the residue at position 297 playing the role of Nucleophile.
+Catalysis involves the residue at position 558 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 787 playing the role of Proton donor.
+Catalysis involves the residue at position 169 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 430 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 935 playing the role of Proton acceptor.
+Catalysis involves the residue at position 86 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 96 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 152 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 250 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 250 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 26 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 118 playing the role of Electrophile.
+Catalysis involves the residue at position 792 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 112 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 244 playing the role of Charge relay system.
+Catalysis involves the residue at position 329 playing the role of Charge relay system.
+Catalysis involves the residue at position 340 playing the role of Charge relay system.
+Catalysis involves the residue at position 167 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 79 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 173 playing the role of For GATase activity.
+Catalysis involves the residue at position 175 playing the role of For GATase activity.
+Catalysis involves the residue at position 1469 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 464 playing the role of .
+Catalysis involves the residue at position 1020 playing the role of Nucleophile.
+Catalysis involves the residue at position 1140 playing the role of Proton acceptor.
+Catalysis involves the residue at position 114 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 314 playing the role of Charge relay system.
+Catalysis involves the residue at position 499 playing the role of Charge relay system.
+Catalysis involves the residue at position 77 playing the role of .
+Catalysis involves the residue at position 1166 playing the role of Nucleophile.
+Catalysis involves the residue at position 1287 playing the role of .
+Catalysis involves the residue at position 1289 playing the role of .
+Catalysis involves the residue at position 333 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 595 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 495 playing the role of Nucleophile.
+Catalysis involves the residue at position 1097 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1391 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 295 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 442 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 498 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 586 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 586 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 571 playing the role of .
+Catalysis involves the residue at position 134 playing the role of Proton donor/acceptor; for FAICAR cyclization activity.
+Catalysis involves the residue at position 295 playing the role of Proton acceptor; for AICAR formyltransferase activity.
+Catalysis involves the residue at position 119 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 226 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 582 playing the role of .
+Catalysis involves the residue at position 638 playing the role of Proton donor.
+Catalysis involves the residue at position 712 playing the role of Charge relay system.
+Catalysis involves the residue at position 922 playing the role of Charge relay system.
+Catalysis involves the residue at position 1018 playing the role of Proton donor.
+Catalysis involves the residue at position 1094 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 271 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 666 playing the role of Proton acceptor.
+Catalysis involves the residue at position 488 playing the role of .
+Catalysis involves the residue at position 405 playing the role of Proton donor.
+Catalysis involves the residue at position 501 playing the role of Nucleophile.
+Catalysis involves the residue at position 663 playing the role of .
+Catalysis involves the residue at position 668 playing the role of .
+Catalysis involves the residue at position 116 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 483 playing the role of .
+Catalysis involves the residue at position 140 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 52 playing the role of Proton acceptor; for glutaminase activity.
+Catalysis involves the residue at position 121 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 176 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 76 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 603 playing the role of Charge relay system.
+Catalysis involves the residue at position 289 playing the role of Proton donor.
+Catalysis involves the residue at position 152 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 302 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 93 playing the role of Electrophile.
+Catalysis involves the residue at position 231 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 384 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 437 playing the role of Proton donor.
+Catalysis involves the residue at position 459 playing the role of Proton donor.
+Catalysis involves the residue at position 535 playing the role of Nucleophile.
+Catalysis involves the residue at position 176 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1588 playing the role of .
+Catalysis involves the residue at position 188 playing the role of Nucleophile.
+Catalysis involves the residue at position 241 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 413 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 277 playing the role of Proton acceptor.
+Catalysis involves the residue at position 779 playing the role of Proton acceptor.
+Catalysis involves the residue at position 30 playing the role of .
+Catalysis involves the residue at position 119 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 306 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 412 playing the role of S-acetylcysteine intermediate.
+Catalysis involves the residue at position 413 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 112 playing the role of Proton acceptor.
+Catalysis involves the residue at position 349 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 200 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 185 playing the role of Charge relay system.
+Catalysis involves the residue at position 447 playing the role of Charge relay system.
+Catalysis involves the residue at position 846 playing the role of .
+Catalysis involves the residue at position 889 playing the role of .
+Catalysis involves the residue at position 101 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 413 playing the role of Proton acceptor.
+Catalysis involves the residue at position 45 playing the role of Proton donor.
+Catalysis involves the residue at position 1137 playing the role of Nucleophile.
+Catalysis involves the residue at position 28 playing the role of Proton acceptor.
+Catalysis involves the residue at position 409 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 28 playing the role of Proton donor.
+Catalysis involves the residue at position 201 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 588 playing the role of Proton donor.
+Catalysis involves the residue at position 730 playing the role of Proton donor.
+Catalysis involves the residue at position 487 playing the role of .
+Catalysis involves the residue at position 129 playing the role of Charge relay system.
+Catalysis involves the residue at position 228 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 15 playing the role of Proton acceptor.
+Catalysis involves the residue at position 258 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 388 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 181 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 183 playing the role of Nucleophile.
+Catalysis involves the residue at position 708 playing the role of Proton donor.
+Catalysis involves the residue at position 686 playing the role of .
+Catalysis involves the residue at position 729 playing the role of .
+Catalysis involves the residue at position 168 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 334 playing the role of For protease activity.
+Catalysis involves the residue at position 461 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 164 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 1163 playing the role of Proton acceptor.
+Catalysis involves the residue at position 727 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 389 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 278 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 383 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 789 playing the role of Proton acceptor.
+Catalysis involves the residue at position 38 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 485 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 320 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 491 playing the role of Nucleophile; for isomaltase activity.
+Catalysis involves the residue at position 590 playing the role of For isomaltase activity.
+Catalysis involves the residue at position 1380 playing the role of Nucleophile; for sucrase activity.
+Catalysis involves the residue at position 1383 playing the role of For sucrase activity.
+Catalysis involves the residue at position 1486 playing the role of Proton donor; for sucrase activity.
+Catalysis involves the residue at position 1436 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1579 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1633 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 598 playing the role of .
+Catalysis involves the residue at position 41 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 185 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 915 playing the role of Proton donor.
+Catalysis involves the residue at position 461 playing the role of .
+Catalysis involves the residue at position 8 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 294 playing the role of Proton donor.
+Catalysis involves the residue at position 113 playing the role of Nucleophile.
+Catalysis involves the residue at position 125 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1137 playing the role of Proton acceptor.
+Catalysis involves the residue at position 319 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 503 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 243 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 32 playing the role of Charge relay system.
+Catalysis involves the residue at position 145 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 1115 playing the role of Proton acceptor.
+Catalysis involves the residue at position 503 playing the role of Proton acceptor.
+Catalysis involves the residue at position 170 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 310 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 347 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 359 playing the role of Nucleophile.
+Catalysis involves the residue at position 418 playing the role of Proton acceptor.
+Catalysis involves the residue at position 447 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 603 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 305 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 184 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 127 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 70 playing the role of Charge relay system.
+Catalysis involves the residue at position 192 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 496 playing the role of Proton donor.
+Catalysis involves the residue at position 62 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 538 playing the role of Proton acceptor.
+Catalysis involves the residue at position 158 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 536 playing the role of Proton acceptor.
+Catalysis involves the residue at position 533 playing the role of .
+Catalysis involves the residue at position 118 playing the role of Charge relay.
+Catalysis involves the residue at position 179 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 304 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 559 playing the role of .
+Catalysis involves the residue at position 638 playing the role of Proton acceptor.
+Catalysis involves the residue at position 758 playing the role of Proton acceptor.
+Catalysis involves the residue at position 162 playing the role of Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity.
+Catalysis involves the residue at position 298 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 653 playing the role of .
+Catalysis involves the residue at position 696 playing the role of .
+Catalysis involves the residue at position 642 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 255 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 131 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 179 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 51 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 580 playing the role of Proton acceptor.
+Catalysis involves the residue at position 920 playing the role of Proton acceptor.
+Catalysis involves the residue at position 510 playing the role of Charge relay system.
+Catalysis involves the residue at position 230 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 482 playing the role of Proton acceptor.
+Catalysis involves the residue at position 484 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 407 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 108 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 230 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 365 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 403 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 699 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1026 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1220 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 167 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 45 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 384 playing the role of Proton donor.
+Catalysis involves the residue at position 178 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1207 playing the role of Proton acceptor.
+Catalysis involves the residue at position 382 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 266 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 411 playing the role of Proton acceptor.
+Catalysis involves the residue at position 295 playing the role of Proton acceptor.
+Catalysis involves the residue at position 293 playing the role of Proton donor.
+Catalysis involves the residue at position 126 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 748 playing the role of .
+Catalysis involves the residue at position 438 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 113 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 174 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 675 playing the role of Proton acceptor.
+Catalysis involves the residue at position 479 playing the role of .
+Catalysis involves the residue at position 398 playing the role of Proton donor.
+Catalysis involves the residue at position 125 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 386 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 129 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 607 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 166 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 699 playing the role of Proton donor.
+Catalysis involves the residue at position 184 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 96 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 110 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 254 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 267 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 465 playing the role of Proton donor.
+Catalysis involves the residue at position 214 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 575 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 83 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 76 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 145 playing the role of For ring-opening step.
+Catalysis involves the residue at position 147 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 152 playing the role of For ring-opening step.
+Catalysis involves the residue at position 840 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 128 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 918 playing the role of Proton acceptor.
+Catalysis involves the residue at position 527 playing the role of Proton donor.
+Catalysis involves the residue at position 168 playing the role of Charge relay system.
+Catalysis involves the residue at position 81 playing the role of Proton donor.
+Catalysis involves the residue at position 57 playing the role of Charge relay system.
+Catalysis involves the residue at position 132 playing the role of Charge relay system.
+Catalysis involves the residue at position 494 playing the role of Proton acceptor.
+Catalysis involves the residue at position 135 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 242 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 610 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 896 playing the role of Proton acceptor.
+Catalysis involves the residue at position 53 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 1037 playing the role of Proton acceptor.
+Catalysis involves the residue at position 239 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 199 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 252 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 300 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 358 playing the role of Nucleophile.
+Catalysis involves the residue at position 410 playing the role of Proton acceptor.
+Catalysis involves the residue at position 532 playing the role of Nucleophile.
+Catalysis involves the residue at position 404 playing the role of Nucleophile.
+Catalysis involves the residue at position 618 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 141 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 827 playing the role of Proton acceptor.
+Catalysis involves the residue at position 793 playing the role of .
+Catalysis involves the residue at position 113 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 622 playing the role of Charge relay system.
+Catalysis involves the residue at position 665 playing the role of Charge relay system.
+Catalysis involves the residue at position 760 playing the role of Charge relay system.
+Catalysis involves the residue at position 77 playing the role of Tele-phosphohistidine intermediate; by HPr.
+Catalysis involves the residue at position 212 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 1084 playing the role of Proton acceptor.
+Catalysis involves the residue at position 18 playing the role of Charge relay system.
+Catalysis involves the residue at position 964 playing the role of Proton acceptor.
+Catalysis involves the residue at position 405 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 212 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 352 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 389 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 185 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 163 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 190 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 195 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 247 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 835 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 3 playing the role of .
+Catalysis involves the residue at position 315 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 127 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 566 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 70 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 392 playing the role of Proton donor.
+Catalysis involves the residue at position 730 playing the role of Charge relay system.
+Catalysis involves the residue at position 311 playing the role of Nucleophile.
+Catalysis involves the residue at position 881 playing the role of Proton acceptor.
+Catalysis involves the residue at position 369 playing the role of Proton acceptor.
+Catalysis involves the residue at position 287 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 191 playing the role of Nucleophile.
+Catalysis involves the residue at position 399 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 239 playing the role of Nucleophile or transition state stabilizer.
+Catalysis involves the residue at position 165 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 129 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 202 playing the role of Nucleophile.
+Catalysis involves the residue at position 608 playing the role of Proton acceptor.
+Catalysis involves the residue at position 68 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 23 playing the role of Charge relay system.
+Catalysis involves the residue at position 68 playing the role of Charge relay system.
+Catalysis involves the residue at position 60 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 773 playing the role of Proton acceptor.
+Catalysis involves the residue at position 191 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 504 playing the role of Proton donor.
+Catalysis involves the residue at position 200 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 610 playing the role of .
+Catalysis involves the residue at position 178 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 94 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 352 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 427 playing the role of Proton acceptor.
+Catalysis involves the residue at position 429 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 579 playing the role of .
+Catalysis involves the residue at position 642 playing the role of .
+Catalysis involves the residue at position 903 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 120 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 499 playing the role of .
+Catalysis involves the residue at position 465 playing the role of .
+Catalysis involves the residue at position 122 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 472 playing the role of Nucleophile.
+Catalysis involves the residue at position 295 playing the role of Proton donor.
+Catalysis involves the residue at position 225 playing the role of Nucleophile.
+Catalysis involves the residue at position 230 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 94 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 402 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 1079 playing the role of Proton acceptor.
+Catalysis involves the residue at position 532 playing the role of Charge relay system.
+Catalysis involves the residue at position 617 playing the role of Charge relay system.
+Catalysis involves the residue at position 652 playing the role of Charge relay system.
+Catalysis involves the residue at position 567 playing the role of Charge relay system.
+Catalysis involves the residue at position 191 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 635 playing the role of Proton acceptor.
+Catalysis involves the residue at position 65 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 251 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 380 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 146 playing the role of Proton donor.
+Catalysis involves the residue at position 164 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 358 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 577 playing the role of Charge relay system.
+Catalysis involves the residue at position 661 playing the role of Charge relay system.
+Catalysis involves the residue at position 698 playing the role of Charge relay system.
+Catalysis involves the residue at position 132 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 134 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 171 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 86 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 246 playing the role of Charge relay system.
+Catalysis involves the residue at position 21 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 16 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 588 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 176 playing the role of Nucleophile.
+Catalysis involves the residue at position 400 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 336 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 438 playing the role of Proton acceptor.
+Catalysis involves the residue at position 175 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 648 playing the role of .
+Catalysis involves the residue at position 119 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 108 playing the role of Charge relay.
+Catalysis involves the residue at position 224 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 493 playing the role of .
+Catalysis involves the residue at position 153 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 12 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 117 playing the role of Nucleophile.
+Catalysis involves the residue at position 433 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 809 playing the role of Proton donor.
+Catalysis involves the residue at position 408 playing the role of Proton acceptor.
+Catalysis involves the residue at position 99 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 457 playing the role of Proton donor.
+Catalysis involves the residue at position 403 playing the role of Charge relay system.
+Catalysis involves the residue at position 443 playing the role of Charge relay system.
+Catalysis involves the residue at position 158 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 650 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 231 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 555 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 425 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 762 playing the role of .
+Catalysis involves the residue at position 216 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 218 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 254 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 305 playing the role of Proton donor/acceptor 1.
+Catalysis involves the residue at position 730 playing the role of Proton donor/acceptor 2.
+Catalysis involves the residue at position 743 playing the role of Proton donor.
+Catalysis involves the residue at position 445 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 728 playing the role of .
+Catalysis involves the residue at position 124 playing the role of Nucleophile.
+Catalysis involves the residue at position 835 playing the role of Proton acceptor.
+Catalysis involves the residue at position 690 playing the role of Proton acceptor.
+Catalysis involves the residue at position 201 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 533 playing the role of Charge relay system.
+Catalysis involves the residue at position 55 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 60 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 75 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 683 playing the role of .
+Catalysis involves the residue at position 199 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 491 playing the role of Proton acceptor.
+Catalysis involves the residue at position 198 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 251 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 103 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 276 playing the role of Nucleophile.
+Catalysis involves the residue at position 367 playing the role of Charge relay system.
+Catalysis involves the residue at position 395 playing the role of Charge relay system.
+Catalysis involves the residue at position 164 playing the role of Nucleophile and monoketide coumarate intermediate.
+Catalysis involves the residue at position 161 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 130 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 716 playing the role of Proton donor.
+Catalysis involves the residue at position 234 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 647 playing the role of .
+Catalysis involves the residue at position 215 playing the role of Proton donor.
+Catalysis involves the residue at position 398 playing the role of .
+Catalysis involves the residue at position 256 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 273 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 118 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 123 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 146 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 460 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 612 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 465 playing the role of Proton acceptor; for hydroxyethylthiazole kinase activity.
+Catalysis involves the residue at position 555 playing the role of .
+Catalysis involves the residue at position 557 playing the role of .
+Catalysis involves the residue at position 276 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 64 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 198 playing the role of Nucleophile.
+Catalysis involves the residue at position 303 playing the role of Proton donor.
+Catalysis involves the residue at position 37 playing the role of Electrophile.
+Catalysis involves the residue at position 110 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 256 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 65 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 133 playing the role of For ring-opening step.
+Catalysis involves the residue at position 135 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 140 playing the role of For ring-opening step.
+Catalysis involves the residue at position 318 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 358 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 985 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1169 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 180 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 315 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 355 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 626 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 954 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1152 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 476 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 438 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 762 playing the role of Proton donor.
+Catalysis involves the residue at position 334 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 335 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 532 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 401 playing the role of Nucleophile.
+Catalysis involves the residue at position 419 playing the role of Proton acceptor.
+Catalysis involves the residue at position 88 playing the role of Proton donor; for both methylation and methoxycarbonylation activities.
+Catalysis involves the residue at position 229 playing the role of Proton acceptor; for methoxycarbonylation activity.
+Catalysis involves the residue at position 432 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 137 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 863 playing the role of .
+Catalysis involves the residue at position 906 playing the role of .
+Catalysis involves the residue at position 548 playing the role of Proton donor.
+Catalysis involves the residue at position 70 playing the role of Proton donor.
+Catalysis involves the residue at position 1123 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 407 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 921 playing the role of Proton acceptor.
+Catalysis involves the residue at position 817 playing the role of Proton acceptor.
+Catalysis involves the residue at position 262 playing the role of Proton donor.
+Catalysis involves the residue at position 104 playing the role of Electrophile.
+Catalysis involves the residue at position 11 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 132 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 88 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 355 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 480 playing the role of Proton donor.
+Catalysis involves the residue at position 219 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 776 playing the role of Proton acceptor.
+Catalysis involves the residue at position 493 playing the role of Proton acceptor.
+Catalysis involves the residue at position 353 playing the role of Nucleophile.
+Catalysis involves the residue at position 452 playing the role of .
+Catalysis involves the residue at position 230 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 408 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 169 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 834 playing the role of Proton acceptor.
+Catalysis involves the residue at position 173 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 490 playing the role of Proton acceptor.
+Catalysis involves the residue at position 553 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 641 playing the role of .
+Catalysis involves the residue at position 296 playing the role of Charge relay system.
+Catalysis involves the residue at position 781 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 196 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 398 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 626 playing the role of Proton acceptor.
+Catalysis involves the residue at position 165 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 168 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 431 playing the role of Proton donor.
+Catalysis involves the residue at position 394 playing the role of Nucleophile.
+Catalysis involves the residue at position 168 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 28 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 495 playing the role of Proton acceptor.
+Catalysis involves the residue at position 585 playing the role of Proton donor.
+Catalysis involves the residue at position 567 playing the role of Proton acceptor.
+Catalysis involves the residue at position 40 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 739 playing the role of .
+Catalysis involves the residue at position 482 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 613 playing the role of Proton acceptor.
+Catalysis involves the residue at position 121 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 245 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 145 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 770 playing the role of .
+Catalysis involves the residue at position 241 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 644 playing the role of .
+Catalysis involves the residue at position 810 playing the role of .
+Catalysis involves the residue at position 835 playing the role of .
+Catalysis involves the residue at position 343 playing the role of Nucleophile.
+Catalysis involves the residue at position 904 playing the role of Proton acceptor.
+Catalysis involves the residue at position 273 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 113 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 169 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 256 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 256 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 663 playing the role of Proton acceptor.
+Catalysis involves the residue at position 167 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 126 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 50 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 310 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 248 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 318 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 404 playing the role of For GATase activity.
+Catalysis involves the residue at position 535 playing the role of For GATase activity.
+Catalysis involves the residue at position 537 playing the role of For GATase activity.
+Catalysis involves the residue at position 362 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 435 playing the role of Proton acceptor.
+Catalysis involves the residue at position 126 playing the role of Charge relay system.
+Catalysis involves the residue at position 566 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 701 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 745 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1018 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1346 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1533 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1973 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 83 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 98 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 431 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 316 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 221 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 279 playing the role of Charge relay system.
+Catalysis involves the residue at position 1136 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 261 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 96 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 388 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 248 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 509 playing the role of Charge relay system.
+Catalysis involves the residue at position 199 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 86 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 32 playing the role of Proton acceptor.
+Catalysis involves the residue at position 909 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 263 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 278 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 819 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1171 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 116 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 83 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 2249 playing the role of .
+Catalysis involves the residue at position 82 playing the role of For formimidoyltransferase activity.
+Catalysis involves the residue at position 413 playing the role of For cyclodeaminase activity.
+Catalysis involves the residue at position 706 playing the role of Charge relay system.
+Catalysis involves the residue at position 738 playing the role of Charge relay system.
+Catalysis involves the residue at position 585 playing the role of Proton acceptor.
+Catalysis involves the residue at position 486 playing the role of .
+Catalysis involves the residue at position 398 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 98 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 67 playing the role of Nucleophile.
+Catalysis involves the residue at position 529 playing the role of Proton donor.
+Catalysis involves the residue at position 558 playing the role of .
+Catalysis involves the residue at position 266 playing the role of Charge relay system.
+Catalysis involves the residue at position 39 playing the role of Proton donor.
+Catalysis involves the residue at position 1266 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 270 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 10 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 557 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 258 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 273 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1170 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1198 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 697 playing the role of Proton donor.
+Catalysis involves the residue at position 244 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 720 playing the role of .
+Catalysis involves the residue at position 425 playing the role of Proton donor.
+Catalysis involves the residue at position 108 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 265 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 397 playing the role of Nucleophile.
+Catalysis involves the residue at position 543 playing the role of Nucleophile.
+Catalysis involves the residue at position 23 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 1275 playing the role of Proton acceptor.
+Catalysis involves the residue at position 531 playing the role of Proton acceptor.
+Catalysis involves the residue at position 302 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 603 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 1198 playing the role of .
+Catalysis involves the residue at position 501 playing the role of Charge relay system.
+Catalysis involves the residue at position 655 playing the role of Charge relay system.
+Catalysis involves the residue at position 114 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 277 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 88 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 242 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 723 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 998 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1514 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1979 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 349 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 926 playing the role of Nucleophile.
+Catalysis involves the residue at position 984 playing the role of Charge relay system.
+Catalysis involves the residue at position 1088 playing the role of For nuclease activity.
+Catalysis involves the residue at position 304 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 99 playing the role of Charge relay system.
+Catalysis involves the residue at position 303 playing the role of Charge relay system.
+Catalysis involves the residue at position 33 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 245 playing the role of Charge relay system.
+Catalysis involves the residue at position 318 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 170 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 225 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 107 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 355 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 511 playing the role of Nucleophile.
+Catalysis involves the residue at position 573 playing the role of Proton donor.
+Catalysis involves the residue at position 146 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 452 playing the role of Proton acceptor.
+Catalysis involves the residue at position 350 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 63 playing the role of Nucleophile.
+Catalysis involves the residue at position 161 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 199 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 628 playing the role of Proton donor.
+Catalysis involves the residue at position 600 playing the role of Proton acceptor.
+Catalysis involves the residue at position 243 playing the role of Charge relay system.
+Catalysis involves the residue at position 423 playing the role of Charge relay system.
+Catalysis involves the residue at position 237 playing the role of Nucleophile or transition state stabilizer.
+Catalysis involves the residue at position 640 playing the role of Proton acceptor.
+Catalysis involves the residue at position 809 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 720 playing the role of Proton acceptor.
+Catalysis involves the residue at position 78 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 132 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 236 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 236 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 13 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 297 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 243 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 1136 playing the role of Nucleophile.
+Catalysis involves the residue at position 261 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 187 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 361 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 233 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 93 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 222 playing the role of Broensted acid.
+Catalysis involves the residue at position 242 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 178 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 236 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 405 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 384 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1843 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 2133 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 262 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 234 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 82 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 87 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 102 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 486 playing the role of Proton donor.
+Catalysis involves the residue at position 186 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 1100 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1394 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 21 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 176 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 476 playing the role of Proton donor.
+Catalysis involves the residue at position 585 playing the role of Charge relay system.
+Catalysis involves the residue at position 705 playing the role of Charge relay system.
+Catalysis involves the residue at position 394 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 565 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 86 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 426 playing the role of Nucleophile; for NAALADase activity.
+Catalysis involves the residue at position 630 playing the role of Charge relay system.
+Catalysis involves the residue at position 668 playing the role of Charge relay system.
+Catalysis involves the residue at position 311 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 313 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 270 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 92 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 403 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 561 playing the role of .
+Catalysis involves the residue at position 726 playing the role of Proton acceptor.
+Catalysis involves the residue at position 327 playing the role of .
+Catalysis involves the residue at position 246 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 740 playing the role of Proton acceptor.
+Catalysis involves the residue at position 732 playing the role of Nucleophile.
+Catalysis involves the residue at position 117 playing the role of Charge relay system.
+Catalysis involves the residue at position 328 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 330 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 175 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 62 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 99 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 384 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 200 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 253 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 825 playing the role of Proton acceptor.
+Catalysis involves the residue at position 428 playing the role of .
+Catalysis involves the residue at position 31 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 755 playing the role of Proton acceptor.
+Catalysis involves the residue at position 115 playing the role of Charge relay.
+Catalysis involves the residue at position 131 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 905 playing the role of .
+Catalysis involves the residue at position 483 playing the role of Proton donor.
+Catalysis involves the residue at position 434 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 273 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 351 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 923 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1092 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 614 playing the role of .
+Catalysis involves the residue at position 680 playing the role of Proton donor.
+Catalysis involves the residue at position 178 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 193 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 471 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 357 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 483 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 319 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 282 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 526 playing the role of Charge relay system.
+Catalysis involves the residue at position 576 playing the role of Charge relay system.
+Catalysis involves the residue at position 699 playing the role of Charge relay system.
+Catalysis involves the residue at position 1004 playing the role of Nucleophile.
+Catalysis involves the residue at position 1124 playing the role of Proton acceptor.
+Catalysis involves the residue at position 833 playing the role of Proton acceptor.
+Catalysis involves the residue at position 217 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 377 playing the role of Nucleophile.
+Catalysis involves the residue at position 566 playing the role of .
+Catalysis involves the residue at position 48 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 511 playing the role of Proton acceptor.
+Catalysis involves the residue at position 352 playing the role of Charge relay system.
+Catalysis involves the residue at position 122 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 691 playing the role of Proton donor.
+Catalysis involves the residue at position 794 playing the role of Proton acceptor.
+Catalysis involves the residue at position 629 playing the role of Nucleophile.
+Catalysis involves the residue at position 658 playing the role of Proton donor.
+Catalysis involves the residue at position 184 playing the role of acceptor.
+Catalysis involves the residue at position 322 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 28 playing the role of Nucleophile.
+Catalysis involves the residue at position 108 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 94 playing the role of Charge relay system.
+Catalysis involves the residue at position 191 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 61 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 331 playing the role of Proton donor.
+Catalysis involves the residue at position 97 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 375 playing the role of Charge relay system.
+Catalysis involves the residue at position 337 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 643 playing the role of Proton acceptor.
+Catalysis involves the residue at position 665 playing the role of .
+Catalysis involves the residue at position 670 playing the role of .
+Catalysis involves the residue at position 205 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 949 playing the role of Proton acceptor.
+Catalysis involves the residue at position 369 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 225 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 492 playing the role of Charge relay system.
+Catalysis involves the residue at position 528 playing the role of Charge relay system.
+Catalysis involves the residue at position 177 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 677 playing the role of Proton acceptor.
+Catalysis involves the residue at position 536 playing the role of Charge relay system.
+Catalysis involves the residue at position 182 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 494 playing the role of .
+Catalysis involves the residue at position 775 playing the role of .
+Catalysis involves the residue at position 388 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 169 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 297 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 92 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 181 playing the role of For GATase activity.
+Catalysis involves the residue at position 183 playing the role of For GATase activity.
+Catalysis involves the residue at position 115 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 171 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 258 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 258 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 121 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 184 playing the role of Glycyl persulfide ester intermediate.
+Catalysis involves the residue at position 126 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1281 playing the role of Proton acceptor.
+Catalysis involves the residue at position 146 playing the role of 1.
+Catalysis involves the residue at position 561 playing the role of 2.
+Catalysis involves the residue at position 582 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1157 playing the role of Nucleophile.
+Catalysis involves the residue at position 186 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 413 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 434 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 472 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 467 playing the role of Proton acceptor.
+Catalysis involves the residue at position 421 playing the role of Proton donor.
+Catalysis involves the residue at position 351 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 535 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 913 playing the role of Proton donor.
+Catalysis involves the residue at position 460 playing the role of Proton donor.
+Catalysis involves the residue at position 547 playing the role of Nucleophile.
+Catalysis involves the residue at position 546 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1296 playing the role of .
+Catalysis involves the residue at position 1298 playing the role of .
+Catalysis involves the residue at position 484 playing the role of Proton donor.
+Catalysis involves the residue at position 505 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 274 playing the role of Charge relay system.
+Catalysis involves the residue at position 417 playing the role of Charge relay system.
+Catalysis involves the residue at position 554 playing the role of Nucleophile.
+Catalysis involves the residue at position 874 playing the role of Proton acceptor.
+Catalysis involves the residue at position 449 playing the role of Proton acceptor.
+Catalysis involves the residue at position 277 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 583 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 552 playing the role of Proton acceptor.
+Catalysis involves the residue at position 279 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 192 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 306 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 171 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 124 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 358 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 220 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 377 playing the role of Proton acceptor.
+Catalysis involves the residue at position 130 playing the role of Charge relay system.
+Catalysis involves the residue at position 673 playing the role of Proton acceptor.
+Catalysis involves the residue at position 357 playing the role of Nucleophile.
+Catalysis involves the residue at position 399 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 317 playing the role of Proton donor.
+Catalysis involves the residue at position 563 playing the role of .
+Catalysis involves the residue at position 130 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 441 playing the role of Proton acceptor.
+Catalysis involves the residue at position 443 playing the role of Nucleophile.
+Catalysis involves the residue at position 70 playing the role of Nucleophile.
+Catalysis involves the residue at position 746 playing the role of Proton donor.
+Catalysis involves the residue at position 753 playing the role of Charge relay system.
+Catalysis involves the residue at position 830 playing the role of Charge relay system.
+Catalysis involves the residue at position 863 playing the role of Charge relay system.
+Catalysis involves the residue at position 468 playing the role of Proton donor.
+Catalysis involves the residue at position 474 playing the role of .
+Catalysis involves the residue at position 703 playing the role of .
+Catalysis involves the residue at position 679 playing the role of Proton acceptor.
+Catalysis involves the residue at position 186 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 498 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 522 playing the role of Proton acceptor.
+Catalysis involves the residue at position 381 playing the role of Proton acceptor.
+Catalysis involves the residue at position 334 playing the role of Proton donor.
+Catalysis involves the residue at position 417 playing the role of Nucleophile; S-glycosyl-cysteine intermediate.
+Catalysis involves the residue at position 818 playing the role of Proton acceptor.
+Catalysis involves the residue at position 181 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 219 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 88 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 941 playing the role of Proton acceptor.
+Catalysis involves the residue at position 125 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 969 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 68 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 571 playing the role of Charge relay system.
+Catalysis involves the residue at position 658 playing the role of .
+Catalysis involves the residue at position 281 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 688 playing the role of Proton acceptor; for protein kinase activity.
+Catalysis involves the residue at position 426 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 85 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 244 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 244 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 119 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 124 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 147 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 353 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 339 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 207 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 506 playing the role of Proton donor.
+Catalysis involves the residue at position 43 playing the role of For GATase activity.
+Catalysis involves the residue at position 53 playing the role of Proton donor.
+Catalysis involves the residue at position 213 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 213 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 508 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 338 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 144 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 322 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 881 playing the role of Nucleophile.
+Catalysis involves the residue at position 240 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 247 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 207 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 712 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1027 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 560 playing the role of Charge relay system.
+Catalysis involves the residue at position 89 playing the role of Electrophile.
+Catalysis involves the residue at position 210 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 815 playing the role of Proton acceptor.
+Catalysis involves the residue at position 283 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 259 playing the role of Charge relay system.
+Catalysis involves the residue at position 2071 playing the role of Proton acceptor.
+Catalysis involves the residue at position 487 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 170 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 203 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 515 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 338 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 535 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 539 playing the role of Charge relay system.
+Catalysis involves the residue at position 46 playing the role of Nucleophile or proton acceptor.
+Catalysis involves the residue at position 621 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 195 playing the role of Charge relay system.
+Catalysis involves the residue at position 514 playing the role of Charge relay system.
+Catalysis involves the residue at position 137 playing the role of Proton donor/acceptor; for FAICAR cyclization activity.
+Catalysis involves the residue at position 267 playing the role of Proton acceptor; for AICAR formyltransferase activity.
+Catalysis involves the residue at position 348 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 461 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 620 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 399 playing the role of Proton acceptor.
+Catalysis involves the residue at position 9 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 603 playing the role of Proton donor.
+Catalysis involves the residue at position 316 playing the role of Proton donor.
+Catalysis involves the residue at position 379 playing the role of Nucleophile.
+Catalysis involves the residue at position 29 playing the role of Proton donor.
+Catalysis involves the residue at position 325 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 521 playing the role of Proton acceptor.
+Catalysis involves the residue at position 599 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 87 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 291 playing the role of Proton acceptor.
+Catalysis involves the residue at position 222 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 113 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1121 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 206 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 470 playing the role of Proton donor.
+Catalysis involves the residue at position 15 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 72 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 118 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 32 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 257 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 46 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 280 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 385 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1116 playing the role of Proton acceptor.
+Catalysis involves the residue at position 100 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 114 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 264 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 277 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 191 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 42 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 412 playing the role of Proton acceptor.
+Catalysis involves the residue at position 496 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 159 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 618 playing the role of Proton donor.
+Catalysis involves the residue at position 493 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 31 playing the role of Schiff-base intermediate with DNA; for 5'-deoxyribose-5-phosphate lyase activity.
+Catalysis involves the residue at position 107 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 476 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 612 playing the role of Proton acceptor.
+Catalysis involves the residue at position 148 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 446 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 370 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 47 playing the role of Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity.
+Catalysis involves the residue at position 140 playing the role of For phospholipase activity.
+Catalysis involves the residue at position 684 playing the role of Nucleophile.
+Catalysis involves the residue at position 685 playing the role of .
+Catalysis involves the residue at position 129 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 246 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 408 playing the role of Proton donor.
+Catalysis involves the residue at position 44 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 59 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 238 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 764 playing the role of Proton acceptor.
+Catalysis involves the residue at position 433 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 990 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 553 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 688 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 733 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1335 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1520 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 286 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 646 playing the role of .
+Catalysis involves the residue at position 259 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 274 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 822 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1166 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1195 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 117 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 128 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 304 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 246 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 83 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 143 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 647 playing the role of Charge relay system.
+Catalysis involves the residue at position 99 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 347 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 333 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 229 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 444 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 686 playing the role of Proton acceptor.
+Catalysis involves the residue at position 141 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 375 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 497 playing the role of .
+Catalysis involves the residue at position 478 playing the role of Proton acceptor.
+Catalysis involves the residue at position 752 playing the role of Charge relay system.
+Catalysis involves the residue at position 829 playing the role of Charge relay system.
+Catalysis involves the residue at position 862 playing the role of Charge relay system.
+Catalysis involves the residue at position 141 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 293 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 411 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 360 playing the role of Nucleophile.
+Catalysis involves the residue at position 182 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 45 playing the role of Charge relay system.
+Catalysis involves the residue at position 397 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 374 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 290 playing the role of Proton acceptor.
+Catalysis involves the residue at position 416 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 438 playing the role of Nucleophile.
+Catalysis involves the residue at position 545 playing the role of Charge relay system.
+Catalysis involves the residue at position 640 playing the role of Charge relay system.
+Catalysis involves the residue at position 473 playing the role of Charge relay system.
+Catalysis involves the residue at position 160 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 785 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 38 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 625 playing the role of .
+Catalysis involves the residue at position 750 playing the role of Proton donor.
+Catalysis involves the residue at position 100 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 11 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 79 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 440 playing the role of Charge relay system.
+Catalysis involves the residue at position 243 playing the role of Nucleophile.
+Catalysis involves the residue at position 347 playing the role of Charge relay system.
+Catalysis involves the residue at position 397 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 289 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 202 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 337 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 372 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 658 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 998 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1187 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 165 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 76 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 1042 playing the role of Proton acceptor.
+Catalysis involves the residue at position 151 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 436 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 726 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 321 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 417 playing the role of Proton acceptor.
+Catalysis involves the residue at position 362 playing the role of Proton donor.
+Catalysis involves the residue at position 89 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 414 playing the role of Proton donor.
+Catalysis involves the residue at position 329 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 498 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 311 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 106 playing the role of Electrophile.
+Catalysis involves the residue at position 94 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 382 playing the role of Nucleophile.
+Catalysis involves the residue at position 549 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 74 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 424 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 55 playing the role of Charge relay system.
+Catalysis involves the residue at position 154 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 707 playing the role of Nucleophile.
+Catalysis involves the residue at position 1153 playing the role of Proton acceptor.
+Catalysis involves the residue at position 64 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 101 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 179 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 19 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 743 playing the role of .
+Catalysis involves the residue at position 90 playing the role of Electrophile.
+Catalysis involves the residue at position 16 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 431 playing the role of Nucleophile.
+Catalysis involves the residue at position 145 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 437 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 641 playing the role of Proton acceptor.
+Catalysis involves the residue at position 452 playing the role of Nucleophile.
+Catalysis involves the residue at position 970 playing the role of Nucleophile.
+Catalysis involves the residue at position 621 playing the role of Proton acceptor.
+Catalysis involves the residue at position 71 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 142 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 147 playing the role of For ring-opening step.
+Catalysis involves the residue at position 674 playing the role of .
+Catalysis involves the residue at position 231 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 257 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 393 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 706 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 335 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 437 playing the role of Proton acceptor.
+Catalysis involves the residue at position 168 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 1481 playing the role of Proton acceptor.
+Catalysis involves the residue at position 273 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 408 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 448 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 720 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1027 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1186 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 516 playing the role of Nucleophile.
+Catalysis involves the residue at position 189 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 551 playing the role of .
+Catalysis involves the residue at position 136 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 204 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 317 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 356 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 230 playing the role of Charge relay system.
+Catalysis involves the residue at position 122 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 369 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 501 playing the role of .
+Catalysis involves the residue at position 192 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 454 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 658 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 356 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 138 playing the role of For GATase activity.
+Catalysis involves the residue at position 643 playing the role of Nucleophile.
+Catalysis involves the residue at position 16 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 390 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 564 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 298 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 554 playing the role of Proton acceptor.
+Catalysis involves the residue at position 90 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 288 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 507 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 703 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 640 playing the role of Proton donor.
+Catalysis involves the residue at position 421 playing the role of Charge relay system.
+Catalysis involves the residue at position 219 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 244 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 344 playing the role of Proton donor.
+Catalysis involves the residue at position 568 playing the role of Proton acceptor.
+Catalysis involves the residue at position 647 playing the role of Proton donor.
+Catalysis involves the residue at position 268 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 437 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 172 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 205 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 475 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 120 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 157 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 322 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 60 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 234 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 593 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 734 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 793 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 880 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 880 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 342 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 344 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 412 playing the role of For cyclodeaminase activity.
+Catalysis involves the residue at position 130 playing the role of Charge relay.
+Catalysis involves the residue at position 448 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 84 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 63 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 90 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 460 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 120 playing the role of Charge relay.
+Catalysis involves the residue at position 280 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 187 playing the role of Nucleophile.
+Catalysis involves the residue at position 55 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 276 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 209 playing the role of Acyl-thioester intermediate; for beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 344 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 384 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 655 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 1263 playing the role of Acyl-ester intermediate; for beta-ketoacyl reductase activity.
+Catalysis involves the residue at position 23 playing the role of Proton donor.
+Catalysis involves the residue at position 206 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 300 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 340 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 920 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1085 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 219 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 477 playing the role of Charge relay system.
+Catalysis involves the residue at position 111 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 489 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 173 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 71 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 155 playing the role of Electrophile.
+Catalysis involves the residue at position 43 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 917 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 13 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 157 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 287 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 401 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 401 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 396 playing the role of Charge relay system.
+Catalysis involves the residue at position 444 playing the role of Proton acceptor.
+Catalysis involves the residue at position 557 playing the role of Nucleophile.
+Catalysis involves the residue at position 42 playing the role of Charge relay system.
+Catalysis involves the residue at position 550 playing the role of Proton acceptor.
+Catalysis involves the residue at position 628 playing the role of Proton acceptor.
+Catalysis involves the residue at position 126 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 14 playing the role of Charge relay system.
+Catalysis involves the residue at position 328 playing the role of Charge relay system.
+Catalysis involves the residue at position 16 playing the role of Tele-phosphohistidine intermediate; for HPr activity.
+Catalysis involves the residue at position 301 playing the role of Tele-phosphohistidine intermediate; for PTS EI activity.
+Catalysis involves the residue at position 614 playing the role of Proton donor; for EI activity.
+Catalysis involves the residue at position 750 playing the role of Tele-phosphohistidine intermediate; for PTS EIIA activity.
+Catalysis involves the residue at position 239 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 412 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 131 playing the role of Charge relay system.
+Catalysis involves the residue at position 155 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 17 playing the role of Nucleophile; for FMN phosphatase activity.
+Catalysis involves the residue at position 19 playing the role of Proton donor; for FMN phosphatase activity.
+Catalysis involves the residue at position 312 playing the role of Nucleophile; for riboflavin kinase activity.
+Catalysis involves the residue at position 111 playing the role of Charge relay.
+Catalysis involves the residue at position 491 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 399 playing the role of Charge relay system.
+Catalysis involves the residue at position 541 playing the role of .
+Catalysis involves the residue at position 290 playing the role of For GATase activity.
+Catalysis involves the residue at position 471 playing the role of Proton donor.
+Catalysis involves the residue at position 128 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 476 playing the role of Charge relay system.
+Catalysis involves the residue at position 286 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 220 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 708 playing the role of Proton acceptor.
+Catalysis involves the residue at position 127 playing the role of Charge relay.
+Catalysis involves the residue at position 60 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 685 playing the role of Proton acceptor.
+Catalysis involves the residue at position 233 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 121 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 363 playing the role of Nucleophile.
+Catalysis involves the residue at position 619 playing the role of Proton acceptor.
+Catalysis involves the residue at position 228 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 403 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 647 playing the role of Nucleophile.
+Catalysis involves the residue at position 115 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 195 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 634 playing the role of Charge relay system.
+Catalysis involves the residue at position 546 playing the role of Nucleophile.
+Catalysis involves the residue at position 289 playing the role of Charge relay system.
+Catalysis involves the residue at position 726 playing the role of .
+Catalysis involves the residue at position 212 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 433 playing the role of Proton donor.
+Catalysis involves the residue at position 490 playing the role of Nucleophile.
+Catalysis involves the residue at position 660 playing the role of Proton donor.
+Catalysis involves the residue at position 82 playing the role of Electrophile.
+Catalysis involves the residue at position 689 playing the role of Proton donor.
+Catalysis involves the residue at position 848 playing the role of Proton acceptor.
+Catalysis involves the residue at position 783 playing the role of Proton acceptor.
+Catalysis involves the residue at position 97 playing the role of Charge relay system.
+Catalysis involves the residue at position 87 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 167 playing the role of Proton donors.
+Catalysis involves the residue at position 112 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 83 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 97 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 246 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 261 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 64 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 130 playing the role of For ring-opening step.
+Catalysis involves the residue at position 132 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 157 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 440 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 157 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 292 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 330 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1001 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1199 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 699 playing the role of Proton acceptor.
+Catalysis involves the residue at position 220 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 189 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 292 playing the role of Proton acceptor.
+Catalysis involves the residue at position 452 playing the role of Charge relay system.
+Catalysis involves the residue at position 15 playing the role of Proton donor.
+Catalysis involves the residue at position 325 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 346 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 444 playing the role of Proton donor.
+Catalysis involves the residue at position 477 playing the role of Nucleophile.
+Catalysis involves the residue at position 987 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 229 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 391 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 165 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 1303 playing the role of Proton acceptor.
+Catalysis involves the residue at position 31 playing the role of Proton donor.
+Catalysis involves the residue at position 90 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 372 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 780 playing the role of Charge relay system.
+Catalysis involves the residue at position 854 playing the role of Charge relay system.
+Catalysis involves the residue at position 888 playing the role of Charge relay system.
+Catalysis involves the residue at position 190 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 267 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 282 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1220 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1248 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 639 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 544 playing the role of .
+Catalysis involves the residue at position 170 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 658 playing the role of Proton acceptor.
+Catalysis involves the residue at position 395 playing the role of Proton acceptor.
+Catalysis involves the residue at position 104 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 793 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 928 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 968 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 423 playing the role of Nucleophile.
+Catalysis involves the residue at position 485 playing the role of .
+Catalysis involves the residue at position 692 playing the role of Proton donor.
+Catalysis involves the residue at position 1029 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1495 playing the role of .
+Catalysis involves the residue at position 475 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 158 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 330 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 284 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 457 playing the role of For protease activity; shared with dimeric partner.
+Catalysis involves the residue at position 100 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 263 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 263 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 360 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 123 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 632 playing the role of Charge relay system.
+Catalysis involves the residue at position 776 playing the role of Charge relay system.
+Catalysis involves the residue at position 511 playing the role of Charge relay system.
+Catalysis involves the residue at position 437 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 11 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 266 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 309 playing the role of Proton donor.
+Catalysis involves the residue at position 128 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 544 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 385 playing the role of Proton donor.
+Catalysis involves the residue at position 497 playing the role of Nucleophile.
+Catalysis involves the residue at position 254 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 855 playing the role of Proton acceptor.
+Catalysis involves the residue at position 819 playing the role of Proton acceptor.
+Catalysis involves the residue at position 489 playing the role of Proton donor.
+Catalysis involves the residue at position 275 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 246 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 807 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 386 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 368 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 454 playing the role of .
+Catalysis involves the residue at position 174 playing the role of For acyltransferase activity.
+Catalysis involves the residue at position 477 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 640 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 114 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 625 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 463 playing the role of Proton acceptor.
+Catalysis involves the residue at position 67 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 416 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 446 playing the role of Proton donor.
+Catalysis involves the residue at position 659 playing the role of Charge relay system.
+Catalysis involves the residue at position 735 playing the role of Charge relay system.
+Catalysis involves the residue at position 834 playing the role of Proton donor.
+Catalysis involves the residue at position 159 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 122 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 430 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 16 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 181 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 320 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 385 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 671 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 997 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1171 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 130 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 249 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 571 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 706 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1524 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 516 playing the role of Charge relay system.
+Catalysis involves the residue at position 604 playing the role of Charge relay system.
+Catalysis involves the residue at position 636 playing the role of Charge relay system.
+Catalysis involves the residue at position 447 playing the role of Nucleophile.
+Catalysis involves the residue at position 198 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 776 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 388 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 173 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 85 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 138 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 328 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 462 playing the role of Proton acceptor.
+Catalysis involves the residue at position 211 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 311 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 895 playing the role of Nucleophile.
+Catalysis involves the residue at position 106 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 168 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 435 playing the role of Nucleophile.
+Catalysis involves the residue at position 124 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 488 playing the role of Nucleophile.
+Catalysis involves the residue at position 324 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 440 playing the role of Proton donor.
+Catalysis involves the residue at position 1049 playing the role of Proton acceptor.
+Catalysis involves the residue at position 701 playing the role of Proton acceptor.
+Catalysis involves the residue at position 313 playing the role of Proton donor.
+Catalysis involves the residue at position 479 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 223 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 63 playing the role of Nucleophile or proton acceptor.
+Catalysis involves the residue at position 403 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 27 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 611 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 275 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 158 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 136 playing the role of Nucleophile.
+Catalysis involves the residue at position 380 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 548 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 398 playing the role of Nucleophile.
+Catalysis involves the residue at position 873 playing the role of .
+Catalysis involves the residue at position 377 playing the role of Proton donor.
+Catalysis involves the residue at position 588 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 657 playing the role of Charge relay system.
+Catalysis involves the residue at position 126 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 131 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 154 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 306 playing the role of Nucleophile.
+Catalysis involves the residue at position 35 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 354 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 588 playing the role of .
+Catalysis involves the residue at position 1185 playing the role of Charge relay system.
+Catalysis involves the residue at position 1233 playing the role of Charge relay system.
+Catalysis involves the residue at position 1332 playing the role of Charge relay system.
+Catalysis involves the residue at position 229 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 393 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 406 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 519 playing the role of Proton acceptor.
+Catalysis involves the residue at position 56 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 63 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 551 playing the role of Proton acceptor.
+Catalysis involves the residue at position 47 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 537 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 672 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 711 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 979 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 2021 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 125 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 269 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 376 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 504 playing the role of .
+Catalysis involves the residue at position 62 playing the role of Charge relay system.
+Catalysis involves the residue at position 436 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 620 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 419 playing the role of Nucleophile.
+Catalysis involves the residue at position 469 playing the role of Proton donor.
+Catalysis involves the residue at position 934 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 88 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 287 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 301 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 18 playing the role of Proton donor.
+Catalysis involves the residue at position 270 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 1361 playing the role of For dehydratase activity.
+Catalysis involves the residue at position 1828 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 366 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 127 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 177 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 542 playing the role of Nucleophile.
+Catalysis involves the residue at position 61 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 98 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 210 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 513 playing the role of Nucleophile.
+Catalysis involves the residue at position 566 playing the role of Proton donor.
+Catalysis involves the residue at position 333 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 17 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 78 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 365 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 248 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 248 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 376 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 397 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 342 playing the role of Charge relay system.
+Catalysis involves the residue at position 48 playing the role of Proton donor.
+Catalysis involves the residue at position 9 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 503 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 228 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 34 playing the role of Nucleophile; methyl group acceptor from methylphosphotriester.
+Catalysis involves the residue at position 441 playing the role of Proton acceptor; for DNA glycosylase activity.
+Catalysis involves the residue at position 167 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 151 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 662 playing the role of .
+Catalysis involves the residue at position 330 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 565 playing the role of .
+Catalysis involves the residue at position 288 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 499 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 190 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 921 playing the role of .
+Catalysis involves the residue at position 978 playing the role of .
+Catalysis involves the residue at position 165 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 336 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 282 playing the role of Nucleophile.
+Catalysis involves the residue at position 119 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 594 playing the role of Proton acceptor.
+Catalysis involves the residue at position 316 playing the role of Charge relay system.
+Catalysis involves the residue at position 13 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 580 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 740 playing the role of .
+Catalysis involves the residue at position 363 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1257 playing the role of Nucleophile.
+Catalysis involves the residue at position 1375 playing the role of Proton acceptor.
+Catalysis involves the residue at position 146 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 139 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 459 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 711 playing the role of .
+Catalysis involves the residue at position 754 playing the role of .
+Catalysis involves the residue at position 401 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 223 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 2069 playing the role of Proton acceptor.
+Catalysis involves the residue at position 210 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 461 playing the role of Proton donor.
+Catalysis involves the residue at position 537 playing the role of Nucleophile.
+Catalysis involves the residue at position 653 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 815 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 737 playing the role of Nucleophile.
+Catalysis involves the residue at position 150 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 1149 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 671 playing the role of Proton acceptor.
+Catalysis involves the residue at position 161 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 220 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 202 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 170 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 500 playing the role of .
+Catalysis involves the residue at position 291 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 83 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 98 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 506 playing the role of Charge relay system.
+Catalysis involves the residue at position 593 playing the role of Charge relay system.
+Catalysis involves the residue at position 625 playing the role of Charge relay system.
+Catalysis involves the residue at position 75 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 376 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 675 playing the role of .
+Catalysis involves the residue at position 456 playing the role of Charge relay system.
+Catalysis involves the residue at position 310 playing the role of Nucleophile.
+Catalysis involves the residue at position 436 playing the role of Nucleophile.
+Catalysis involves the residue at position 433 playing the role of Charge relay system.
+Catalysis involves the residue at position 620 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 91 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 41 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 379 playing the role of Proton donor.
+Catalysis involves the residue at position 46 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 131 playing the role of Charge relay.
+Catalysis involves the residue at position 592 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 230 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 459 playing the role of Charge relay system.
+Catalysis involves the residue at position 421 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 594 playing the role of .
+Catalysis involves the residue at position 159 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 701 playing the role of Proton donor.
+Catalysis involves the residue at position 424 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 445 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 373 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 107 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 610 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1695 playing the role of Nucleophile.
+Catalysis involves the residue at position 1967 playing the role of Proton acceptor.
+Catalysis involves the residue at position 400 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 421 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 78 playing the role of Proton acceptor in CI (KaiC 1).
+Catalysis involves the residue at position 318 playing the role of Proton acceptor in CII (KaiC 2).
+Catalysis involves the residue at position 29 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 248 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 528 playing the role of Proton donor.
+Catalysis involves the residue at position 175 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 363 playing the role of Proton donor.
+Catalysis involves the residue at position 885 playing the role of .
+Catalysis involves the residue at position 166 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 417 playing the role of Proton donor.
+Catalysis involves the residue at position 192 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 329 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 369 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 652 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 974 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1154 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 582 playing the role of Proton acceptor.
+Catalysis involves the residue at position 293 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 127 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 521 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 656 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 695 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 274 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 414 playing the role of For protease activity; shared with dimeric partner.
+Catalysis involves the residue at position 217 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 377 playing the role of Charge relay system.
+Catalysis involves the residue at position 331 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 333 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 361 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 779 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 429 playing the role of Charge relay system.
+Catalysis involves the residue at position 582 playing the role of Charge relay system.
+Catalysis involves the residue at position 176 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 631 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 961 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1136 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 448 playing the role of Proton donor.
+Catalysis involves the residue at position 983 playing the role of Nucleophile.
+Catalysis involves the residue at position 1103 playing the role of Proton acceptor.
+Catalysis involves the residue at position 455 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 320 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1279 playing the role of Proton donor.
+Catalysis involves the residue at position 383 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 654 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 942 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1111 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 587 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 94 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 619 playing the role of .
+Catalysis involves the residue at position 740 playing the role of Nucleophile.
+Catalysis involves the residue at position 52 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 1313 playing the role of Proton acceptor.
+Catalysis involves the residue at position 275 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 186 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 325 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 368 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 644 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 970 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1146 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 91 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 307 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 340 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 191 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 216 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 392 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 125 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 146 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 930 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 484 playing the role of .
+Catalysis involves the residue at position 434 playing the role of Proton donor.
+Catalysis involves the residue at position 590 playing the role of .
+Catalysis involves the residue at position 476 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 132 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 250 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 539 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 674 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 713 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1314 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1499 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 221 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 453 playing the role of Charge relay system.
+Catalysis involves the residue at position 181 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 283 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 253 playing the role of Nucleophile.
+Catalysis involves the residue at position 116 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 648 playing the role of Charge relay system.
+Catalysis involves the residue at position 15 playing the role of Pros-phosphohistidine intermediate; for HPr activity.
+Catalysis involves the residue at position 298 playing the role of Tele-phosphohistidine intermediate; for PTS EI activity.
+Catalysis involves the residue at position 611 playing the role of Proton donor; for EI activity.
+Catalysis involves the residue at position 747 playing the role of Tele-phosphohistidine intermediate; for PTS EIIA activity.
+Catalysis involves the residue at position 91 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 647 playing the role of Proton acceptor.
+Catalysis involves the residue at position 294 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 505 playing the role of Proton donor.
+Catalysis involves the residue at position 299 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 335 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 640 playing the role of Proton acceptor; for G6PD activity.
+Catalysis involves the residue at position 123 playing the role of Charge relay.
+Catalysis involves the residue at position 157 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 417 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 601 playing the role of Nucleophile.
+Catalysis involves the residue at position 353 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 211 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 757 playing the role of .
+Catalysis involves the residue at position 800 playing the role of .
+Catalysis involves the residue at position 451 playing the role of Nucleophile.
+Catalysis involves the residue at position 28 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 602 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 577 playing the role of Proton donor.
+Catalysis involves the residue at position 491 playing the role of Proton donor.
+Catalysis involves the residue at position 590 playing the role of Nucleophile.
+Catalysis involves the residue at position 247 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 268 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 363 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 695 playing the role of .
+Catalysis involves the residue at position 11 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 341 playing the role of Nucleophile.
+Catalysis involves the residue at position 445 playing the role of .
+Catalysis involves the residue at position 183 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 1270 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 127 playing the role of Electrophile.
+Catalysis involves the residue at position 497 playing the role of Charge relay system.
+Catalysis involves the residue at position 598 playing the role of Charge relay system.
+Catalysis involves the residue at position 202 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 652 playing the role of Proton acceptor.
+Catalysis involves the residue at position 391 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 827 playing the role of .
+Catalysis involves the residue at position 870 playing the role of .
+Catalysis involves the residue at position 62 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 19 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 821 playing the role of .
+Catalysis involves the residue at position 890 playing the role of .
+Catalysis involves the residue at position 1061 playing the role of .
+Catalysis involves the residue at position 383 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 414 playing the role of Nucleophile.
+Catalysis involves the residue at position 706 playing the role of Proton donor.
+Catalysis involves the residue at position 883 playing the role of .
+Catalysis involves the residue at position 146 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 1406 playing the role of Nucleophile.
+Catalysis involves the residue at position 1524 playing the role of Proton acceptor.
+Catalysis involves the residue at position 564 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 312 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 705 playing the role of Proton acceptor.
+Catalysis involves the residue at position 234 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 450 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 281 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 313 playing the role of Nucleophile.
+Catalysis involves the residue at position 549 playing the role of Charge relay system.
+Catalysis involves the residue at position 666 playing the role of Charge relay system.
+Catalysis involves the residue at position 18 playing the role of For GATase activity.
+Catalysis involves the residue at position 128 playing the role of For GATase activity.
+Catalysis involves the residue at position 221 playing the role of For GATase activity.
+Catalysis involves the residue at position 223 playing the role of For GATase activity.
+Catalysis involves the residue at position 87 playing the role of Charge relay system.
+Catalysis involves the residue at position 760 playing the role of Proton acceptor.
+Catalysis involves the residue at position 375 playing the role of Proton donor.
+Catalysis involves the residue at position 661 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 977 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 120 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 687 playing the role of .
+Catalysis involves the residue at position 236 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 415 playing the role of Proton donor.
+Catalysis involves the residue at position 823 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1179 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1207 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 781 playing the role of Proton acceptor.
+Catalysis involves the residue at position 415 playing the role of Charge relay system.
+Catalysis involves the residue at position 491 playing the role of Charge relay system.
+Catalysis involves the residue at position 589 playing the role of Proton donor.
+Catalysis involves the residue at position 354 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 463 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 67 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 381 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 768 playing the role of Proton acceptor.
+Catalysis involves the residue at position 489 playing the role of Proton acceptor.
+Catalysis involves the residue at position 190 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 209 playing the role of Proton donors.
+Catalysis involves the residue at position 251 playing the role of Nucleophile.
+Catalysis involves the residue at position 1057 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 764 playing the role of Nucleophile.
+Catalysis involves the residue at position 796 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 802 playing the role of Proton acceptor.
+Catalysis involves the residue at position 560 playing the role of .
+Catalysis involves the residue at position 247 playing the role of Charge relay system.
+Catalysis involves the residue at position 72 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 270 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 1982 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 169 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 2 playing the role of Schiff-base intermediate with DNA; via amino nitrogen.
+Catalysis involves the residue at position 580 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 312 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 498 playing the role of Proton donor.
+Catalysis involves the residue at position 179 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 531 playing the role of Proton donor.
+Catalysis involves the residue at position 249 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 822 playing the role of .
+Catalysis involves the residue at position 459 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 251 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 495 playing the role of Proton donor.
+Catalysis involves the residue at position 403 playing the role of Proton donor.
+Catalysis involves the residue at position 191 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 398 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 161 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 537 playing the role of Proton acceptor.
+Catalysis involves the residue at position 556 playing the role of Proton acceptor.
+Catalysis involves the residue at position 24 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 100 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 402 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 508 playing the role of Nucleophile.
+Catalysis involves the residue at position 235 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 192 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 629 playing the role of Charge relay system.
+Catalysis involves the residue at position 739 playing the role of Charge relay system.
+Catalysis involves the residue at position 22 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 223 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 463 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 615 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 278 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 133 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 188 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 441 playing the role of Charge relay system.
+Catalysis involves the residue at position 236 playing the role of Charge relay system.
+Catalysis involves the residue at position 274 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 353 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 238 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 567 playing the role of .
+Catalysis involves the residue at position 630 playing the role of .
+Catalysis involves the residue at position 540 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 584 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 17 playing the role of Nucleophile.
+Catalysis involves the residue at position 19 playing the role of Proton donor.
+Catalysis involves the residue at position 14 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 304 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 82 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 469 playing the role of Charge relay system.
+Catalysis involves the residue at position 6 playing the role of Proton donor.
+Catalysis involves the residue at position 390 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 249 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 249 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 387 playing the role of Proton donor.
+Catalysis involves the residue at position 111 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 418 playing the role of Proton donor.
+Catalysis involves the residue at position 49 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 622 playing the role of Nucleophile.
+Catalysis involves the residue at position 895 playing the role of Proton acceptor.
+Catalysis involves the residue at position 591 playing the role of Nucleophile.
+Catalysis involves the residue at position 508 playing the role of Proton acceptor.
+Catalysis involves the residue at position 681 playing the role of .
+Catalysis involves the residue at position 724 playing the role of .
+Catalysis involves the residue at position 241 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 481 playing the role of Proton donor.
+Catalysis involves the residue at position 686 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 727 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1004 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1341 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1536 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1916 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 886 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 183 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 635 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 973 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1159 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 309 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 409 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 319 playing the role of Charge relay system.
+Catalysis involves the residue at position 707 playing the role of .
+Catalysis involves the residue at position 709 playing the role of .
+Catalysis involves the residue at position 714 playing the role of .
+Catalysis involves the residue at position 526 playing the role of Nucleophile.
+Catalysis involves the residue at position 186 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 15 playing the role of Pros-phosphohistidine intermediate; alternate.
+Catalysis involves the residue at position 457 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 459 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 152 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 189 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 655 playing the role of Proton acceptor.
+Catalysis involves the residue at position 860 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 438 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 459 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 512 playing the role of Charge relay system.
+Catalysis involves the residue at position 453 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 533 playing the role of Nucleophile.
+Catalysis involves the residue at position 101 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 302 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 147 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 372 playing the role of Proton donor.
+Catalysis involves the residue at position 488 playing the role of Proton acceptor.
+Catalysis involves the residue at position 261 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 261 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 669 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1858 playing the role of Proton acceptor.
+Catalysis involves the residue at position 748 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 302 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 803 playing the role of .
+Catalysis involves the residue at position 396 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 581 playing the role of .
+Catalysis involves the residue at position 584 playing the role of .
+Catalysis involves the residue at position 104 playing the role of Charge relay system.
+Catalysis involves the residue at position 84 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 313 playing the role of Charge relay system.
+Catalysis involves the residue at position 410 playing the role of Charge relay system.
+Catalysis involves the residue at position 247 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 395 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 124 playing the role of Charge relay.
+Catalysis involves the residue at position 71 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 687 playing the role of Proton donor.
+Catalysis involves the residue at position 543 playing the role of .
+Catalysis involves the residue at position 166 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 260 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 440 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 140 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 346 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 184 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 361 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 641 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 338 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 340 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 316 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 78 playing the role of Nucleophile; for sulfatase activity.
+Catalysis involves the residue at position 766 playing the role of Proton donor; for alpha-L-rhamnosidase activity.
+Catalysis involves the residue at position 1044 playing the role of Proton acceptor; for alpha-L-rhamnosidase activity.
+Catalysis involves the residue at position 175 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 172 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 779 playing the role of .
+Catalysis involves the residue at position 315 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 891 playing the role of Proton acceptor.
+Catalysis involves the residue at position 263 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 636 playing the role of Proton acceptor.
+Catalysis involves the residue at position 809 playing the role of Proton acceptor.
+Catalysis involves the residue at position 356 playing the role of Nucleophile.
+Catalysis involves the residue at position 796 playing the role of .
+Catalysis involves the residue at position 610 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 66 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 607 playing the role of Proton donor.
+Catalysis involves the residue at position 878 playing the role of Proton acceptor.
+Catalysis involves the residue at position 409 playing the role of Proton acceptor.
+Catalysis involves the residue at position 136 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 66 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 137 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 142 playing the role of For ring-opening step.
+Catalysis involves the residue at position 414 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 699 playing the role of .
+Catalysis involves the residue at position 742 playing the role of .
+Catalysis involves the residue at position 195 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 359 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 378 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 473 playing the role of Nucleophile.
+Catalysis involves the residue at position 646 playing the role of Charge relay system.
+Catalysis involves the residue at position 483 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 300 playing the role of Proton donor.
+Catalysis involves the residue at position 39 playing the role of Charge relay system.
+Catalysis involves the residue at position 235 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 609 playing the role of Charge relay system.
+Catalysis involves the residue at position 719 playing the role of Proton acceptor.
+Catalysis involves the residue at position 718 playing the role of Proton donor.
+Catalysis involves the residue at position 96 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 443 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 767 playing the role of .
+Catalysis involves the residue at position 151 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 426 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 236 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 181 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 568 playing the role of .
+Catalysis involves the residue at position 495 playing the role of .
+Catalysis involves the residue at position 775 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 302 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 171 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 695 playing the role of Proton donor.
+Catalysis involves the residue at position 1159 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 91 playing the role of Electrophile.
+Catalysis involves the residue at position 106 playing the role of For GATase activity.
+Catalysis involves the residue at position 38 playing the role of Nucleophile; methyl group acceptor from methylphosphotriester.
+Catalysis involves the residue at position 321 playing the role of Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine.
+Catalysis involves the residue at position 63 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 107 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 242 playing the role of Proton donor.
+Catalysis involves the residue at position 269 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 109 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 246 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 408 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 85 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 193 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 997 playing the role of Proton acceptor.
+Catalysis involves the residue at position 455 playing the role of Charge relay system.
+Catalysis involves the residue at position 553 playing the role of Proton donor.
+Catalysis involves the residue at position 591 playing the role of Proton acceptor.
+Catalysis involves the residue at position 741 playing the role of .
+Catalysis involves the residue at position 784 playing the role of .
+Catalysis involves the residue at position 225 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 26 playing the role of Proton donor.
+Catalysis involves the residue at position 305 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 297 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 214 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 180 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 731 playing the role of Proton donor.
+Catalysis involves the residue at position 342 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 780 playing the role of .
+Catalysis involves the residue at position 180 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 302 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 342 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 219 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 264 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 180 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 91 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 67 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 560 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 71 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 499 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 184 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 717 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 500 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 604 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 747 playing the role of Proton acceptor.
+Catalysis involves the residue at position 121 playing the role of Charge relay.
+Catalysis involves the residue at position 924 playing the role of Proton donor.
+Catalysis involves the residue at position 295 playing the role of Nucleophile.
+Catalysis involves the residue at position 330 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 301 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 105 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 87 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 433 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 536 playing the role of Nucleophile.
+Catalysis involves the residue at position 331 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 970 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 507 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 509 playing the role of Proton donor.
+Catalysis involves the residue at position 80 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 217 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 133 playing the role of Charge relay.
+Catalysis involves the residue at position 1267 playing the role of Proton acceptor.
+Catalysis involves the residue at position 637 playing the role of Proton acceptor.
+Catalysis involves the residue at position 112 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 809 playing the role of Charge relay system.
+Catalysis involves the residue at position 865 playing the role of Charge relay system.
+Catalysis involves the residue at position 966 playing the role of Charge relay system.
+Catalysis involves the residue at position 164 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 169 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 309 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 236 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 249 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 178 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 360 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 486 playing the role of Charge relay system.
+Catalysis involves the residue at position 41 playing the role of Proton acceptor; for glutaminase activity.
+Catalysis involves the residue at position 109 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 145 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 613 playing the role of Charge relay system.
+Catalysis involves the residue at position 725 playing the role of Charge relay system.
+Catalysis involves the residue at position 376 playing the role of Proton donor.
+Catalysis involves the residue at position 540 playing the role of Charge relay system.
+Catalysis involves the residue at position 172 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 200 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 367 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 92 playing the role of Electrophile.
+Catalysis involves the residue at position 262 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 984 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1151 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 587 playing the role of Proton acceptor.
+Catalysis involves the residue at position 77 playing the role of Proton acceptor; for D-DAP ammonia-lyase activity.
+Catalysis involves the residue at position 120 playing the role of Proton acceptor; for L-DAP ammonia-lyase activity.
+Catalysis involves the residue at position 777 playing the role of .
+Catalysis involves the residue at position 589 playing the role of .
+Catalysis involves the residue at position 203 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 111 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 240 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 424 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 20 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 435 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 616 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 118 playing the role of Charge relay system.
+Catalysis involves the residue at position 96 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 443 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 332 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 138 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 176 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 566 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 186 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 234 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 195 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 568 playing the role of Proton donor.
+Catalysis involves the residue at position 1215 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 330 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 354 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 1004 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 107 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 33 playing the role of Charge relay system.
+Catalysis involves the residue at position 945 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 822 playing the role of Charge relay system.
+Catalysis involves the residue at position 956 playing the role of Charge relay system.
+Catalysis involves the residue at position 1032 playing the role of Charge relay system.
+Catalysis involves the residue at position 1128 playing the role of Proton donor.
+Catalysis involves the residue at position 213 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 655 playing the role of Nucleophile.
+Catalysis involves the residue at position 136 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 285 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 266 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 447 playing the role of Proton donor.
+Catalysis involves the residue at position 1200 playing the role of Proton acceptor.
+Catalysis involves the residue at position 234 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 174 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 431 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 144 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 244 playing the role of Proton acceptor; for UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase activity.
+Catalysis involves the residue at position 523 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 239 playing the role of For deubiquitinase activity.
+Catalysis involves the residue at position 242 playing the role of Nucleophile; for deubiquitinase activity.
+Catalysis involves the residue at position 345 playing the role of For deubiquitinase activity.
+Catalysis involves the residue at position 950 playing the role of .
+Catalysis involves the residue at position 993 playing the role of .
+Catalysis involves the residue at position 277 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 303 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 401 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 643 playing the role of Proton donor.
+Catalysis involves the residue at position 668 playing the role of Proton acceptor.
+Catalysis involves the residue at position 69 playing the role of Charge relay system.
+Catalysis involves the residue at position 455 playing the role of Proton donor.
+Catalysis involves the residue at position 1148 playing the role of Proton acceptor.
+Catalysis involves the residue at position 181 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 218 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 248 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 351 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 160 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 223 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 293 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 535 playing the role of Charge relay system.
+Catalysis involves the residue at position 586 playing the role of Charge relay system.
+Catalysis involves the residue at position 110 playing the role of Schiff-base intermediate with acetoacetate.
+Catalysis involves the residue at position 369 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 286 playing the role of Charge relay system.
+Catalysis involves the residue at position 496 playing the role of Charge relay system.
+Catalysis involves the residue at position 448 playing the role of Charge relay system.
+Catalysis involves the residue at position 187 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 274 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 94 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 14 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 353 playing the role of Proton donor/acceptor 1.
+Catalysis involves the residue at position 771 playing the role of Proton donor/acceptor 2.
+Catalysis involves the residue at position 284 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 442 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 2095 playing the role of Proton acceptor.
+Catalysis involves the residue at position 627 playing the role of .
+Catalysis involves the residue at position 547 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 682 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 721 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 935 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1255 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1437 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 971 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 358 playing the role of Charge relay system.
+Catalysis involves the residue at position 408 playing the role of Charge relay system.
+Catalysis involves the residue at position 913 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1297 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 1299 playing the role of Proton acceptor.
+Catalysis involves the residue at position 460 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 259 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 328 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 118 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 726 playing the role of Charge relay system.
+Catalysis involves the residue at position 803 playing the role of Charge relay system.
+Catalysis involves the residue at position 317 playing the role of Charge relay system.
+Catalysis involves the residue at position 310 playing the role of Charge relay system.
+Catalysis involves the residue at position 778 playing the role of Nucleophile.
+Catalysis involves the residue at position 807 playing the role of Proton donor.
+Catalysis involves the residue at position 216 playing the role of 1.
+Catalysis involves the residue at position 611 playing the role of 2.
+Catalysis involves the residue at position 261 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 532 playing the role of .
+Catalysis involves the residue at position 1037 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 525 playing the role of Charge relay system.
+Catalysis involves the residue at position 1981 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 366 playing the role of Nucleophile.
+Catalysis involves the residue at position 729 playing the role of Charge relay system.
+Catalysis involves the residue at position 807 playing the role of Charge relay system.
+Catalysis involves the residue at position 839 playing the role of Charge relay system.
+Catalysis involves the residue at position 354 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 871 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 530 playing the role of .
+Catalysis involves the residue at position 180 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 252 playing the role of For GATase activity.
+Catalysis involves the residue at position 336 playing the role of For GATase activity.
+Catalysis involves the residue at position 338 playing the role of For GATase activity.
+Catalysis involves the residue at position 12 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 540 playing the role of .
+Catalysis involves the residue at position 888 playing the role of Proton acceptor.
+Catalysis involves the residue at position 44 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 634 playing the role of Proton donor.
+Catalysis involves the residue at position 774 playing the role of .
+Catalysis involves the residue at position 712 playing the role of .
+Catalysis involves the residue at position 170 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 544 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 679 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 718 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1320 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1506 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 778 playing the role of .
+Catalysis involves the residue at position 935 playing the role of .
+Catalysis involves the residue at position 1058 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1212 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1253 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 185 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 244 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 143 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 498 playing the role of Proton acceptor.
+Catalysis involves the residue at position 438 playing the role of Charge relay system.
+Catalysis involves the residue at position 91 playing the role of Electron donor/acceptor.
+Catalysis involves the residue at position 915 playing the role of .
+Catalysis involves the residue at position 345 playing the role of Nucleophile.
+Catalysis involves the residue at position 188 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 127 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 29 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 138 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 143 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 166 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 146 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 183 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 236 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 632 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 89 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 494 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 629 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 668 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 904 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1221 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1402 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2159 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2320 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2352 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 581 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 878 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1031 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2308 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2481 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 196 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 1161 playing the role of Proton acceptor.
+Catalysis involves the residue at position 257 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 84 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 342 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 143 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 58 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 710 playing the role of Proton acceptor.
+Catalysis involves the residue at position 248 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 267 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 142 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 179 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 61 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 202 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 524 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 750 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 179 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 356 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 184 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 38 playing the role of Charge relay system.
+Catalysis involves the residue at position 377 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 426 playing the role of Proton acceptor.
+Catalysis involves the residue at position 343 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 364 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 632 playing the role of Proton donor.
+Catalysis involves the residue at position 461 playing the role of Nucleophile.
+Catalysis involves the residue at position 138 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 254 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 163 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 891 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 524 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 187 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 291 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 957 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1148 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 487 playing the role of Proton donor.
+Catalysis involves the residue at position 114 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 544 playing the role of Proton acceptor.
+Catalysis involves the residue at position 749 playing the role of Proton donor.
+Catalysis involves the residue at position 231 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 400 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 284 playing the role of Charge relay system.
+Catalysis involves the residue at position 516 playing the role of Proton donor.
+Catalysis involves the residue at position 220 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 422 playing the role of For GATase activity.
+Catalysis involves the residue at position 424 playing the role of For GATase activity.
+Catalysis involves the residue at position 133 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 163 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 792 playing the role of .
+Catalysis involves the residue at position 98 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 327 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1158 playing the role of Proton acceptor.
+Catalysis involves the residue at position 253 playing the role of Charge relay system.
+Catalysis involves the residue at position 177 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 456 playing the role of .
+Catalysis involves the residue at position 922 playing the role of .
+Catalysis involves the residue at position 991 playing the role of .
+Catalysis involves the residue at position 1151 playing the role of .
+Catalysis involves the residue at position 98 playing the role of For GATase activity.
+Catalysis involves the residue at position 901 playing the role of .
+Catalysis involves the residue at position 551 playing the role of Nucleophile.
+Catalysis involves the residue at position 807 playing the role of Proton acceptor.
+Catalysis involves the residue at position 360 playing the role of For GATase activity.
+Catalysis involves the residue at position 365 playing the role of Charge relay system.
+Catalysis involves the residue at position 590 playing the role of Charge relay system.
+Catalysis involves the residue at position 382 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 412 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 148 playing the role of Charge relay system.
+Catalysis involves the residue at position 483 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 559 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 394 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 528 playing the role of .
+Catalysis involves the residue at position 374 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 447 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 1146 playing the role of Nucleophile.
+Catalysis involves the residue at position 1280 playing the role of .
+Catalysis involves the residue at position 1282 playing the role of .
+Catalysis involves the residue at position 91 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 405 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 67 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 37 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 177 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 121 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 505 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 684 playing the role of Proton acceptor.
+Catalysis involves the residue at position 988 playing the role of Nucleophile.
+Catalysis involves the residue at position 388 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 431 playing the role of Charge relay system.
+Catalysis involves the residue at position 480 playing the role of Charge relay system.
+Catalysis involves the residue at position 272 playing the role of Charge relay system.
+Catalysis involves the residue at position 475 playing the role of Charge relay system.
+Catalysis involves the residue at position 112 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 496 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 882 playing the role of Proton acceptor.
+Catalysis involves the residue at position 230 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 230 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 279 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 368 playing the role of Charge relay system.
+Catalysis involves the residue at position 486 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 532 playing the role of For mutarotase activity.
+Catalysis involves the residue at position 266 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 121 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 295 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 61 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 756 playing the role of Nucleophile.
+Catalysis involves the residue at position 814 playing the role of Charge relay system.
+Catalysis involves the residue at position 362 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 318 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 540 playing the role of Proton acceptor.
+Catalysis involves the residue at position 428 playing the role of Charge relay system.
+Catalysis involves the residue at position 105 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 351 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 310 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 281 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 118 playing the role of Schiff-base intermediate with acetoacetate.
+Catalysis involves the residue at position 524 playing the role of Proton acceptor.
+Catalysis involves the residue at position 334 playing the role of Charge relay system.
+Catalysis involves the residue at position 809 playing the role of .
+Catalysis involves the residue at position 89 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 981 playing the role of Proton acceptor.
+Catalysis involves the residue at position 334 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 340 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 874 playing the role of .
+Catalysis involves the residue at position 111 playing the role of Proton donor/acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 134 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 279 playing the role of Proton acceptor; for shikimate dehydrogenase activity.
+Catalysis involves the residue at position 430 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 587 playing the role of Nucleophile.
+Catalysis involves the residue at position 886 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 235 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 458 playing the role of Proton acceptor.
+Catalysis involves the residue at position 479 playing the role of Proton donor.
+Catalysis involves the residue at position 466 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 624 playing the role of Charge relay system.
+Catalysis involves the residue at position 667 playing the role of Charge relay system.
+Catalysis involves the residue at position 745 playing the role of Proton acceptor.
+Catalysis involves the residue at position 2375 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 302 playing the role of For GATase activity.
+Catalysis involves the residue at position 386 playing the role of For GATase activity.
+Catalysis involves the residue at position 388 playing the role of For GATase activity.
+Catalysis involves the residue at position 57 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 655 playing the role of .
+Catalysis involves the residue at position 157 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 2079 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1086 playing the role of For nuclease activity.
+Catalysis involves the residue at position 337 playing the role of Proton donor.
+Catalysis involves the residue at position 613 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 427 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 255 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 428 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 430 playing the role of Proton acceptor.
+Catalysis involves the residue at position 132 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 393 playing the role of Charge relay system.
+Catalysis involves the residue at position 138 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 703 playing the role of Proton acceptor.
+Catalysis involves the residue at position 222 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 393 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 378 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 175 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 274 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 565 playing the role of Nucleophile.
+Catalysis involves the residue at position 688 playing the role of Proton acceptor.
+Catalysis involves the residue at position 98 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 72 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 1698 playing the role of Nucleophile.
+Catalysis involves the residue at position 1970 playing the role of Proton acceptor.
+Catalysis involves the residue at position 84 playing the role of Redox-active.
+Catalysis involves the residue at position 87 playing the role of Redox-active.
+Catalysis involves the residue at position 2408 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 566 playing the role of For molybdenum cofactor biosynthesis protein C activity.
+Catalysis involves the residue at position 694 playing the role of Proton acceptor.
+Catalysis involves the residue at position 862 playing the role of Proton acceptor.
+Catalysis involves the residue at position 159 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 220 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 254 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 573 playing the role of Charge relay system.
+Catalysis involves the residue at position 626 playing the role of Charge relay system.
+Catalysis involves the residue at position 320 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 106 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 526 playing the role of Proton acceptor.
+Catalysis involves the residue at position 842 playing the role of Proton acceptor.
+Catalysis involves the residue at position 172 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 693 playing the role of Proton acceptor.
+Catalysis involves the residue at position 237 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 73 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 78 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 93 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 30 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 622 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 664 playing the role of Proton donor.
+Catalysis involves the residue at position 594 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 509 playing the role of Proton acceptor.
+Catalysis involves the residue at position 110 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1143 playing the role of Nucleophile.
+Catalysis involves the residue at position 1268 playing the role of .
+Catalysis involves the residue at position 1270 playing the role of .
+Catalysis involves the residue at position 679 playing the role of .
+Catalysis involves the residue at position 722 playing the role of .
+Catalysis involves the residue at position 319 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 300 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 485 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 261 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 335 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 837 playing the role of Proton acceptor.
+Catalysis involves the residue at position 143 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 198 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 413 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 60 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 288 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 645 playing the role of .
+Catalysis involves the residue at position 649 playing the role of .
+Catalysis involves the residue at position 1025 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 724 playing the role of Charge relay system.
+Catalysis involves the residue at position 801 playing the role of Charge relay system.
+Catalysis involves the residue at position 834 playing the role of Charge relay system.
+Catalysis involves the residue at position 215 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 51 playing the role of Charge relay system.
+Catalysis involves the residue at position 708 playing the role of Charge relay system.
+Catalysis involves the residue at position 740 playing the role of Charge relay system.
+Catalysis involves the residue at position 43 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 288 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 219 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1929 playing the role of Proton acceptor.
+Catalysis involves the residue at position 173 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 606 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1264 playing the role of Proton donor.
+Catalysis involves the residue at position 187 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 855 playing the role of .
+Catalysis involves the residue at position 190 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 443 playing the role of Proton donor.
+Catalysis involves the residue at position 190 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 408 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 813 playing the role of .
+Catalysis involves the residue at position 1258 playing the role of Nucleophile.
+Catalysis involves the residue at position 1376 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1761 playing the role of .
+Catalysis involves the residue at position 1919 playing the role of .
+Catalysis involves the residue at position 1939 playing the role of .
+Catalysis involves the residue at position 581 playing the role of Charge relay system.
+Catalysis involves the residue at position 701 playing the role of Charge relay system.
+Catalysis involves the residue at position 176 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 87 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 457 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 79 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 857 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 427 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 278 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 627 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 471 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 188 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1063 playing the role of Proton donor; for phlorizin hydrolase/Glycosylceramidase activity.
+Catalysis involves the residue at position 1271 playing the role of Nucleophile; for phlorizin hydrolase/Glycosylceramidase activity.
+Catalysis involves the residue at position 1536 playing the role of Proton donor; for lactase activity.
+Catalysis involves the residue at position 1747 playing the role of Nucleophile; for lactase activity.
+Catalysis involves the residue at position 93 playing the role of Charge relay.
+Catalysis involves the residue at position 323 playing the role of Charge relay system.
+Catalysis involves the residue at position 880 playing the role of Proton acceptor.
+Catalysis involves the residue at position 899 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 956 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 1043 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 1043 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 816 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1168 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1196 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 563 playing the role of Charge relay system.
+Catalysis involves the residue at position 678 playing the role of Charge relay system.
+Catalysis involves the residue at position 396 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 444 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 702 playing the role of Proton acceptor.
+Catalysis involves the residue at position 359 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 801 playing the role of Nucleophile.
+Catalysis involves the residue at position 922 playing the role of Proton acceptor.
+Catalysis involves the residue at position 762 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1065 playing the role of For nuclease activity.
+Catalysis involves the residue at position 122 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 805 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 487 playing the role of Nucleophile.
+Catalysis involves the residue at position 267 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 258 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 28 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 315 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 532 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 910 playing the role of Proton donor.
+Catalysis involves the residue at position 183 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 570 playing the role of Nucleophile.
+Catalysis involves the residue at position 789 playing the role of .
+Catalysis involves the residue at position 178 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 473 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 142 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 266 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 281 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1226 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 783 playing the role of .
+Catalysis involves the residue at position 127 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 131 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 410 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 412 playing the role of Charge relay system.
+Catalysis involves the residue at position 152 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 797 playing the role of .
+Catalysis involves the residue at position 954 playing the role of .
+Catalysis involves the residue at position 176 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 43 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 523 playing the role of Charge relay system.
+Catalysis involves the residue at position 548 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 683 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 725 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1001 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1511 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1967 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 237 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 841 playing the role of Charge relay system.
+Catalysis involves the residue at position 892 playing the role of Charge relay system.
+Catalysis involves the residue at position 987 playing the role of Charge relay system.
+Catalysis involves the residue at position 134 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 977 playing the role of Nucleophile.
+Catalysis involves the residue at position 1097 playing the role of Proton acceptor.
+Catalysis involves the residue at position 3 playing the role of Nucleophile.
+Catalysis involves the residue at position 360 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 381 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 389 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 463 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 330 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 723 playing the role of .
+Catalysis involves the residue at position 1003 playing the role of .
+Catalysis involves the residue at position 597 playing the role of Proton donor.
+Catalysis involves the residue at position 702 playing the role of Nucleophile.
+Catalysis involves the residue at position 187 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 471 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 451 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 144 playing the role of Charge relay system.
+Catalysis involves the residue at position 294 playing the role of Charge relay system.
+Catalysis involves the residue at position 555 playing the role of Charge relay system.
+Catalysis involves the residue at position 138 playing the role of Proton donor/acceptor; for FAICAR cyclization activity.
+Catalysis involves the residue at position 279 playing the role of Proton acceptor; for AICAR formyltransferase activity.
+Catalysis involves the residue at position 83 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 386 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 477 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 336 playing the role of For protease activity; shared with dimeric partner.
+Catalysis involves the residue at position 37 playing the role of Charge relay system.
+Catalysis involves the residue at position 138 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 335 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 337 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 363 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 646 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 964 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1134 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 459 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 835 playing the role of Proton donor.
+Catalysis involves the residue at position 215 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 330 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 1032 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2302 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2475 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 265 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 320 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 29 playing the role of Proton acceptor.
+Catalysis involves the residue at position 388 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 678 playing the role of .
+Catalysis involves the residue at position 320 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 161 playing the role of Proton acceptor; specific for (R)-substrate epimerization.
+Catalysis involves the residue at position 265 playing the role of Proton acceptor; specific for (S)-substrate epimerization.
+Catalysis involves the residue at position 378 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 308 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 111 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 206 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 272 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 744 playing the role of Proton acceptor.
+Catalysis involves the residue at position 168 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 113 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 391 playing the role of Proton donor.
+Catalysis involves the residue at position 1930 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 234 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1767 playing the role of Proton acceptor.
+Catalysis involves the residue at position 321 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1776 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 515 playing the role of Nucleophile.
+Catalysis involves the residue at position 1023 playing the role of Proton donor.
+Catalysis involves the residue at position 301 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 286 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 159 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 336 playing the role of Charge relay system.
+Catalysis involves the residue at position 338 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 105 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 344 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 253 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 714 playing the role of Charge relay system.
+Catalysis involves the residue at position 848 playing the role of Charge relay system.
+Catalysis involves the residue at position 924 playing the role of Charge relay system.
+Catalysis involves the residue at position 1022 playing the role of Proton donor.
+Catalysis involves the residue at position 487 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 331 playing the role of Charge relay system.
+Catalysis involves the residue at position 680 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 746 playing the role of .
+Catalysis involves the residue at position 456 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 434 playing the role of Charge relay system.
+Catalysis involves the residue at position 483 playing the role of Charge relay system.
+Catalysis involves the residue at position 578 playing the role of Charge relay system.
+Catalysis involves the residue at position 354 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 8 playing the role of Proton donor.
+Catalysis involves the residue at position 343 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 147 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 306 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 909 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1093 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1969 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 192 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 782 playing the role of Proton donor.
+Catalysis involves the residue at position 447 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 692 playing the role of Proton acceptor.
+Catalysis involves the residue at position 529 playing the role of Charge relay system.
+Catalysis involves the residue at position 631 playing the role of Charge relay system.
+Catalysis involves the residue at position 371 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 227 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 558 playing the role of Proton acceptor.
+Catalysis involves the residue at position 494 playing the role of Charge relay system.
+Catalysis involves the residue at position 181 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 616 playing the role of Proton acceptor.
+Catalysis involves the residue at position 121 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 190 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 424 playing the role of Charge relay system.
+Catalysis involves the residue at position 1117 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1265 playing the role of Proton acceptor.
+Catalysis involves the residue at position 370 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 659 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1189 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 763 playing the role of Proton acceptor.
+Catalysis involves the residue at position 994 playing the role of Nucleophile.
+Catalysis involves the residue at position 1114 playing the role of Proton acceptor.
+Catalysis involves the residue at position 638 playing the role of .
+Catalysis involves the residue at position 877 playing the role of Proton acceptor.
+Catalysis involves the residue at position 33 playing the role of Proton acceptor.
+Catalysis involves the residue at position 743 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1302 playing the role of Proton acceptor.
+Catalysis involves the residue at position 49 playing the role of Cysteine sulfenic acid (-SOH) intermediate; for peroxiredoxin activity.
+Catalysis involves the residue at position 308 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 343 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 555 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 893 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1079 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 248 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1044 playing the role of Nucleophile.
+Catalysis involves the residue at position 657 playing the role of .
+Catalysis involves the residue at position 219 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 364 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 399 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 903 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1077 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 963 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1141 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 268 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 203 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 500 playing the role of Proton donor.
+Catalysis involves the residue at position 1175 playing the role of Proton acceptor.
+Catalysis involves the residue at position 104 playing the role of For GATase activity.
+Catalysis involves the residue at position 190 playing the role of For GATase activity.
+Catalysis involves the residue at position 192 playing the role of For GATase activity.
+Catalysis involves the residue at position 661 playing the role of Proton acceptor.
+Catalysis involves the residue at position 614 playing the role of Proton donor.
+Catalysis involves the residue at position 78 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 338 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 26 playing the role of Charge relay system.
+Catalysis involves the residue at position 641 playing the role of Proton donor.
+Catalysis involves the residue at position 593 playing the role of Proton acceptor.
+Catalysis involves the residue at position 23 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 114 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 169 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 82 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 221 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 745 playing the role of Nucleophile.
+Catalysis involves the residue at position 1209 playing the role of Proton acceptor.
+Catalysis involves the residue at position 586 playing the role of Proton acceptor.
+Catalysis involves the residue at position 489 playing the role of Nucleophile.
+Catalysis involves the residue at position 1140 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1933 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1071 playing the role of Proton acceptor.
+Catalysis involves the residue at position 367 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 361 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 184 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 85 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 59 playing the role of S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine intermediate.
+Catalysis involves the residue at position 849 playing the role of .
+Catalysis involves the residue at position 79 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 111 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 233 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 138 playing the role of Electrophile.
+Catalysis involves the residue at position 644 playing the role of Charge relay system.
+Catalysis involves the residue at position 676 playing the role of Charge relay system.
+Catalysis involves the residue at position 829 playing the role of .
+Catalysis involves the residue at position 299 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 145 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 630 playing the role of Proton donor.
+Catalysis involves the residue at position 163 playing the role of Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity.
+Catalysis involves the residue at position 649 playing the role of Proton acceptor.
+Catalysis involves the residue at position 615 playing the role of .
+Catalysis involves the residue at position 617 playing the role of .
+Catalysis involves the residue at position 622 playing the role of .
+Catalysis involves the residue at position 16 playing the role of For GATase activity.
+Catalysis involves the residue at position 1452 playing the role of Proton acceptor.
+Catalysis involves the residue at position 428 playing the role of Nucleophile.
+Catalysis involves the residue at position 674 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1182 playing the role of Proton acceptor.
+Catalysis involves the residue at position 204 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 763 playing the role of .
+Catalysis involves the residue at position 612 playing the role of Proton donor.
+Catalysis involves the residue at position 985 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 648 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1566 playing the role of .
+Catalysis involves the residue at position 87 playing the role of Electrophile.
+Catalysis involves the residue at position 308 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 8 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1670 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1961 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 395 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 475 playing the role of Nucleophile.
+Catalysis involves the residue at position 222 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 317 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 282 playing the role of Proton acceptor.
+Catalysis involves the residue at position 379 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1245 playing the role of Nucleophile.
+Catalysis involves the residue at position 1363 playing the role of Proton acceptor.
+Catalysis involves the residue at position 306 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 816 playing the role of .
+Catalysis involves the residue at position 446 playing the role of Charge relay system.
+Catalysis involves the residue at position 716 playing the role of Proton acceptor.
+Catalysis involves the residue at position 380 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 730 playing the role of .
+Catalysis involves the residue at position 755 playing the role of .
+Catalysis involves the residue at position 231 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 319 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 119 playing the role of Charge relay.
+Catalysis involves the residue at position 1450 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 841 playing the role of Proton acceptor.
+Catalysis involves the residue at position 761 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 30 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 56 playing the role of Cysteine sulfenic acid (-SOH) intermediate (for peroxiredoxin activity).
+Catalysis involves the residue at position 179 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 87 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 1500 playing the role of Proton acceptor.
+Catalysis involves the residue at position 204 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 257 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 72 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 77 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 520 playing the role of Charge relay system.
+Catalysis involves the residue at position 1014 playing the role of Proton acceptor.
+Catalysis involves the residue at position 271 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 113 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 206 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 218 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 36 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 308 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 405 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 78 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 210 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 386 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 100 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 45 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 559 playing the role of Proton acceptor.
+Catalysis involves the residue at position 535 playing the role of .
+Catalysis involves the residue at position 538 playing the role of .
+Catalysis involves the residue at position 201 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 22 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 307 playing the role of Proton donor.
+Catalysis involves the residue at position 325 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 439 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 365 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 843 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 53 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 166 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 290 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 274 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 98 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 547 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 365 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 59 playing the role of Charge relay system.
+Catalysis involves the residue at position 377 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 839 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 778 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1253 playing the role of Proton acceptor.
+Catalysis involves the residue at position 92 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 1218 playing the role of .
+Catalysis involves the residue at position 119 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 616 playing the role of Charge relay system.
+Catalysis involves the residue at position 693 playing the role of Charge relay system.
+Catalysis involves the residue at position 728 playing the role of Charge relay system.
+Catalysis involves the residue at position 798 playing the role of .
+Catalysis involves the residue at position 36 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 545 playing the role of Nucleophile.
+Catalysis involves the residue at position 385 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 333 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 1034 playing the role of .
+Catalysis involves the residue at position 1963 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 612 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 958 playing the role of For nuclease activity.
+Catalysis involves the residue at position 394 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 179 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 670 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 672 playing the role of Proton acceptor.
+Catalysis involves the residue at position 495 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 153 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 847 playing the role of .
+Catalysis involves the residue at position 174 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 212 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 140 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 561 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 696 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 737 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 277 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 608 playing the role of Nucleophile.
+Catalysis involves the residue at position 345 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 260 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 329 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 502 playing the role of Proton acceptor.
+Catalysis involves the residue at position 471 playing the role of Charge relay system.
+Catalysis involves the residue at position 2203 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 820 playing the role of .
+Catalysis involves the residue at position 566 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 350 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 717 playing the role of Proton acceptor.
+Catalysis involves the residue at position 168 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 149 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 589 playing the role of Charge relay system.
+Catalysis involves the residue at position 325 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 74 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 79 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 94 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 955 playing the role of .
+Catalysis involves the residue at position 998 playing the role of .
+Catalysis involves the residue at position 454 playing the role of Nucleophile.
+Catalysis involves the residue at position 149 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 952 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 479 playing the role of Nucleophile.
+Catalysis involves the residue at position 800 playing the role of Proton acceptor.
+Catalysis involves the residue at position 134 playing the role of For ring-opening step.
+Catalysis involves the residue at position 136 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 481 playing the role of Nucleophile.
+Catalysis involves the residue at position 335 playing the role of Proton donor.
+Catalysis involves the residue at position 99 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 178 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 196 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 248 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 422 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 454 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 839 playing the role of Proton donor.
+Catalysis involves the residue at position 118 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 629 playing the role of Proton acceptor.
+Catalysis involves the residue at position 126 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 142 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 36 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 1040 playing the role of .
+Catalysis involves the residue at position 375 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 460 playing the role of Nucleophile.
+Catalysis involves the residue at position 317 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 189 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 385 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 310 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 116 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 5 playing the role of Charge relay system.
+Catalysis involves the residue at position 616 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 382 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 245 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 250 playing the role of Nucleophile.
+Catalysis involves the residue at position 45 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 110 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 67 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 604 playing the role of Proton donor.
+Catalysis involves the residue at position 709 playing the role of Nucleophile.
+Catalysis involves the residue at position 149 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 780 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 430 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 790 playing the role of Proton acceptor.
+Catalysis involves the residue at position 211 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 209 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 348 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 64 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 717 playing the role of Proton donor.
+Catalysis involves the residue at position 875 playing the role of Proton acceptor.
+Catalysis involves the residue at position 363 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 420 playing the role of Charge relay system.
+Catalysis involves the residue at position 392 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 283 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 227 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 602 playing the role of Proton acceptor.
+Catalysis involves the residue at position 231 playing the role of Charge relay system.
+Catalysis involves the residue at position 565 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 700 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 743 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1354 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1543 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 493 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 112 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 959 playing the role of .
+Catalysis involves the residue at position 1002 playing the role of .
+Catalysis involves the residue at position 364 playing the role of Proton donor.
+Catalysis involves the residue at position 120 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 91 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 549 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 684 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 997 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1312 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 2250 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2412 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 390 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 645 playing the role of Proton donor.
+Catalysis involves the residue at position 1162 playing the role of Nucleophile.
+Catalysis involves the residue at position 556 playing the role of .
+Catalysis involves the residue at position 188 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 194 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 1023 playing the role of Proton acceptor.
+Catalysis involves the residue at position 242 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 282 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 186 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 133 playing the role of Schiff-base intermediate with KHG or pyruvate.
+Catalysis involves the residue at position 216 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 391 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 667 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 972 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1129 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 104 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 169 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 355 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 193 playing the role of Proton donor; for cellulase activity.
+Catalysis involves the residue at position 316 playing the role of Nucleophile; for cellulase activity.
+Catalysis involves the residue at position 612 playing the role of Nucleophile; for esterase activity.
+Catalysis involves the residue at position 112 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 775 playing the role of Proton acceptor.
+Catalysis involves the residue at position 131 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 402 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 462 playing the role of Charge relay system.
+Catalysis involves the residue at position 560 playing the role of Proton donor.
+Catalysis involves the residue at position 771 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 16 playing the role of Proton donor.
+Catalysis involves the residue at position 385 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 487 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 492 playing the role of Proton donor.
+Catalysis involves the residue at position 38 playing the role of Nucleophile; methyl group acceptor from phosphotriester.
+Catalysis involves the residue at position 321 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 766 playing the role of Charge relay system.
+Catalysis involves the residue at position 865 playing the role of Proton donor.
+Catalysis involves the residue at position 606 playing the role of .
+Catalysis involves the residue at position 203 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 557 playing the role of Proton acceptor.
+Catalysis involves the residue at position 217 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 390 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 672 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1003 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 667 playing the role of .
+Catalysis involves the residue at position 196 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 884 playing the role of .
+Catalysis involves the residue at position 304 playing the role of Proton donor.
+Catalysis involves the residue at position 933 playing the role of Proton acceptor.
+Catalysis involves the residue at position 606 playing the role of Charge relay system.
+Catalysis involves the residue at position 162 playing the role of Proton acceptor; specific for (R)-substrate epimerization.
+Catalysis involves the residue at position 268 playing the role of Proton acceptor; specific for (S)-substrate epimerization.
+Catalysis involves the residue at position 172 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 17 playing the role of Charge relay system.
+Catalysis involves the residue at position 403 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 43 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 109 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 1080 playing the role of For nuclease activity.
+Catalysis involves the residue at position 694 playing the role of .
+Catalysis involves the residue at position 113 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 164 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 101 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 701 playing the role of Nucleophile.
+Catalysis involves the residue at position 1304 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1546 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1587 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 157 playing the role of Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity.
+Catalysis involves the residue at position 622 playing the role of Proton acceptor.
+Catalysis involves the residue at position 427 playing the role of Proton donor.
+Catalysis involves the residue at position 371 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 62 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 416 playing the role of Proton donor.
+Catalysis involves the residue at position 51 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 838 playing the role of .
+Catalysis involves the residue at position 881 playing the role of .
+Catalysis involves the residue at position 518 playing the role of Charge relay system.
+Catalysis involves the residue at position 328 playing the role of Proton donor.
+Catalysis involves the residue at position 145 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 656 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 420 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 441 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 664 playing the role of Proton acceptor.
+Catalysis involves the residue at position 903 playing the role of Charge relay system.
+Catalysis involves the residue at position 936 playing the role of Charge relay system.
+Catalysis involves the residue at position 468 playing the role of Nucleophile.
+Catalysis involves the residue at position 890 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 776 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 407 playing the role of Proton acceptor.
+Catalysis involves the residue at position 112 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 510 playing the role of Nucleophile.
+Catalysis involves the residue at position 2201 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 132 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 395 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 416 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 539 playing the role of For GATase activity.
+Catalysis involves the residue at position 247 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 276 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 291 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 838 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1187 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1215 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1285 playing the role of .
+Catalysis involves the residue at position 202 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 254 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 567 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 703 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1027 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 609 playing the role of Proton acceptor.
+Catalysis involves the residue at position 786 playing the role of Nucleophile.
+Catalysis involves the residue at position 1067 playing the role of Proton acceptor.
+Catalysis involves the residue at position 342 playing the role of For GATase activity.
+Catalysis involves the residue at position 426 playing the role of For GATase activity.
+Catalysis involves the residue at position 428 playing the role of For GATase activity.
+Catalysis involves the residue at position 368 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 139 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 220 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 256 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 186 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 278 playing the role of Proton donor.
+Catalysis involves the residue at position 328 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 808 playing the role of Charge relay system.
+Catalysis involves the residue at position 840 playing the role of Charge relay system.
+Catalysis involves the residue at position 213 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 366 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 725 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 367 playing the role of Nucleophile.
+Catalysis involves the residue at position 447 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 305 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 572 playing the role of Proton donor.
+Catalysis involves the residue at position 186 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 474 playing the role of Proton donor.
+Catalysis involves the residue at position 1597 playing the role of Proton acceptor.
+Catalysis involves the residue at position 442 playing the role of Charge relay system.
+Catalysis involves the residue at position 204 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 339 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 379 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1113 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1170 playing the role of Proton donor; for the o-succinylbenzoate synthase activity.
+Catalysis involves the residue at position 1279 playing the role of Proton acceptor; for the o-succinylbenzoate synthase activity.
+Catalysis involves the residue at position 144 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 1531 playing the role of .
+Catalysis involves the residue at position 499 playing the role of Nucleophile.
+Catalysis involves the residue at position 185 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 468 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 558 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 602 playing the role of Nucleophile.
+Catalysis involves the residue at position 250 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 1128 playing the role of Proton acceptor.
+Catalysis involves the residue at position 467 playing the role of Nucleophile.
+Catalysis involves the residue at position 470 playing the role of Nucleophile.
+Catalysis involves the residue at position 541 playing the role of Nucleophile.
+Catalysis involves the residue at position 564 playing the role of Proton acceptor.
+Catalysis involves the residue at position 481 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 438 playing the role of Proton donor.
+Catalysis involves the residue at position 471 playing the role of Nucleophile.
+Catalysis involves the residue at position 163 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 322 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 919 playing the role of .
+Catalysis involves the residue at position 902 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 354 playing the role of Nucleophile.
+Catalysis involves the residue at position 409 playing the role of Proton donor.
+Catalysis involves the residue at position 430 playing the role of Nucleophile.
+Catalysis involves the residue at position 432 playing the role of Nucleophile.
+Catalysis involves the residue at position 1305 playing the role of Proton acceptor.
+Catalysis involves the residue at position 367 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 886 playing the role of Proton acceptor.
+Catalysis involves the residue at position 192 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 376 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 113 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 250 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 233 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 381 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 279 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 111 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 991 playing the role of Nucleophile.
+Catalysis involves the residue at position 1111 playing the role of Proton acceptor.
+Catalysis involves the residue at position 184 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 455 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 61 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 253 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 368 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 193 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 107 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 551 playing the role of Proton donor.
+Catalysis involves the residue at position 119 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 32 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 206 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 195 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 324 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 194 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 619 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 111 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 417 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 1310 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1491 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2251 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2413 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2445 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 258 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 1267 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 445 playing the role of Nucleophile.
+Catalysis involves the residue at position 639 playing the role of Proton acceptor.
+Catalysis involves the residue at position 14 playing the role of Nucleophile; cysteine thioarsenate intermediate.
+Catalysis involves the residue at position 1169 playing the role of Nucleophile.
+Catalysis involves the residue at position 1287 playing the role of Proton acceptor.
+Catalysis involves the residue at position 823 playing the role of Proton acceptor.
+Catalysis involves the residue at position 332 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 255 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 137 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 235 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 248 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 536 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 378 playing the role of Proton donor.
+Catalysis involves the residue at position 275 playing the role of For GATase activity.
+Catalysis involves the residue at position 361 playing the role of For GATase activity.
+Catalysis involves the residue at position 363 playing the role of For GATase activity.
+Catalysis involves the residue at position 699 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 151 playing the role of Proton acceptor; specific for (R)-substrate epimerization.
+Catalysis involves the residue at position 247 playing the role of Proton acceptor; specific for (S)-substrate epimerization.
+Catalysis involves the residue at position 1013 playing the role of Proton acceptor.
+Catalysis involves the residue at position 858 playing the role of Proton acceptor.
+Catalysis involves the residue at position 35 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 139 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 46 playing the role of Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity.
+Catalysis involves the residue at position 139 playing the role of For phospholipase activity.
+Catalysis involves the residue at position 340 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 434 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 182 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 60 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 188 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 264 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 375 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 375 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 595 playing the role of Proton donor.
+Catalysis involves the residue at position 313 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 782 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 521 playing the role of Charge relay system.
+Catalysis involves the residue at position 392 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 507 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 103 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 274 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 1808 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 117 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 824 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 1133 playing the role of Proton donor.
+Catalysis involves the residue at position 201 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 130 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 519 playing the role of Nucleophile.
+Catalysis involves the residue at position 261 playing the role of Charge relay system.
+Catalysis involves the residue at position 1022 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1194 playing the role of Proton acceptor.
+Catalysis involves the residue at position 319 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 360 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 48 playing the role of Charge relay system.
+Catalysis involves the residue at position 200 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 380 playing the role of Nucleophile.
+Catalysis involves the residue at position 1085 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1380 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1167 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 592 playing the role of Proton acceptor.
+Catalysis involves the residue at position 335 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 407 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 52 playing the role of Schiff-base intermediate with DNA; for 5'-deoxyribose-5-phosphate lyase activity.
+Catalysis involves the residue at position 117 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 372 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 499 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 976 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1174 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1822 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 117 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 197 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 2233 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 86 playing the role of Electrophile.
+Catalysis involves the residue at position 214 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 537 playing the role of Charge relay system.
+Catalysis involves the residue at position 584 playing the role of Proton donor.
+Catalysis involves the residue at position 159 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 252 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1019 playing the role of Charge relay system.
+Catalysis involves the residue at position 436 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 324 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 117 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 129 playing the role of Schiff-base intermediate with KHG or pyruvate.
+Catalysis involves the residue at position 542 playing the role of Charge relay system.
+Catalysis involves the residue at position 627 playing the role of Charge relay system.
+Catalysis involves the residue at position 121 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 815 playing the role of .
+Catalysis involves the residue at position 948 playing the role of .
+Catalysis involves the residue at position 287 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 343 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 704 playing the role of Proton acceptor.
+Catalysis involves the residue at position 706 playing the role of Proton acceptor.
+Catalysis involves the residue at position 742 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1263 playing the role of Proton donor.
+Catalysis involves the residue at position 287 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 128 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 374 playing the role of Charge relay system.
+Catalysis involves the residue at position 54 playing the role of For GATase activity.
+Catalysis involves the residue at position 1077 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 236 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 93 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 107 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 255 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 268 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 458 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 431 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 440 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 321 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 755 playing the role of Charge relay system.
+Catalysis involves the residue at position 898 playing the role of Charge relay system.
+Catalysis involves the residue at position 662 playing the role of Proton acceptor.
+Catalysis involves the residue at position 580 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 597 playing the role of .
+Catalysis involves the residue at position 98 playing the role of Charge relay system.
+Catalysis involves the residue at position 84 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 52 playing the role of Charge relay system.
+Catalysis involves the residue at position 412 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 556 playing the role of Proton donor.
+Catalysis involves the residue at position 599 playing the role of Proton acceptor.
+Catalysis involves the residue at position 385 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 331 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 734 playing the role of Charge relay system.
+Catalysis involves the residue at position 867 playing the role of Charge relay system.
+Catalysis involves the residue at position 943 playing the role of Charge relay system.
+Catalysis involves the residue at position 1039 playing the role of Proton donor.
+Catalysis involves the residue at position 306 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 402 playing the role of Proton acceptor.
+Catalysis involves the residue at position 840 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1243 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1271 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 810 playing the role of Proton acceptor.
+Catalysis involves the residue at position 660 playing the role of Proton acceptor.
+Catalysis involves the residue at position 890 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1059 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 7 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 912 playing the role of Nucleophile.
+Catalysis involves the residue at position 131 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 233 playing the role of For deubiquitinase activity.
+Catalysis involves the residue at position 236 playing the role of Nucleophile; for deubiquitinase activity.
+Catalysis involves the residue at position 339 playing the role of For deubiquitinase activity.
+Catalysis involves the residue at position 89 playing the role of Phosphothreonine intermediate.
+Catalysis involves the residue at position 300 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1162 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1191 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1390 playing the role of Proton acceptor.
+Catalysis involves the residue at position 106 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 173 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 199 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 296 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 408 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 408 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 437 playing the role of Nucleophile.
+Catalysis involves the residue at position 385 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 644 playing the role of Nucleophile.
+Catalysis involves the residue at position 558 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 694 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1344 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1529 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 253 playing the role of Proton acceptor; for ribokinase activity.
+Catalysis involves the residue at position 417 playing the role of Proton acceptor; for ribose-5-phosphate isomerase activity.
+Catalysis involves the residue at position 657 playing the role of Proton acceptor.
+Catalysis involves the residue at position 369 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 165 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 575 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 980 playing the role of Nucleophile.
+Catalysis involves the residue at position 1100 playing the role of Proton acceptor.
+Catalysis involves the residue at position 393 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 550 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 116 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 517 playing the role of For GATase activity.
+Catalysis involves the residue at position 602 playing the role of For GATase activity.
+Catalysis involves the residue at position 604 playing the role of For GATase activity.
+Catalysis involves the residue at position 164 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 853 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1169 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 244 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 362 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 785 playing the role of Charge relay system.
+Catalysis involves the residue at position 212 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 218 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 314 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 374 playing the role of Nucleophile.
+Catalysis involves the residue at position 748 playing the role of Proton donor.
+Catalysis involves the residue at position 302 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 439 playing the role of Charge relay system.
+Catalysis involves the residue at position 541 playing the role of Charge relay system.
+Catalysis involves the residue at position 174 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 638 playing the role of Charge relay system.
+Catalysis involves the residue at position 198 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 637 playing the role of Charge relay system.
+Catalysis involves the residue at position 15 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1141 playing the role of .
+Catalysis involves the residue at position 314 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 23 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 447 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 772 playing the role of Proton donor.
+Catalysis involves the residue at position 379 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 680 playing the role of .
+Catalysis involves the residue at position 853 playing the role of .
+Catalysis involves the residue at position 194 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 962 playing the role of Charge relay system.
+Catalysis involves the residue at position 1038 playing the role of Charge relay system.
+Catalysis involves the residue at position 1134 playing the role of Proton donor.
+Catalysis involves the residue at position 80 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 85 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 158 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 118 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 498 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 484 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 211 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 1073 playing the role of Proton acceptor.
+Catalysis involves the residue at position 105 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 123 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 698 playing the role of Proton acceptor.
+Catalysis involves the residue at position 429 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 221 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 162 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 46 playing the role of Proton acceptor; for glutaminase activity.
+Catalysis involves the residue at position 151 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 444 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 111 playing the role of For glutaminase activity.
+Catalysis involves the residue at position 147 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 679 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 153 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 257 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 257 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 543 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 678 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1345 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1937 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 842 playing the role of .
+Catalysis involves the residue at position 337 playing the role of Charge relay system.
+Catalysis involves the residue at position 339 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 341 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 501 playing the role of Proton acceptor.
+Catalysis involves the residue at position 388 playing the role of Proton donor.
+Catalysis involves the residue at position 382 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 83 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 305 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 194 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 837 playing the role of Charge relay system.
+Catalysis involves the residue at position 1289 playing the role of Proton acceptor.
+Catalysis involves the residue at position 570 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 680 playing the role of Proton acceptor.
+Catalysis involves the residue at position 62 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 290 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 732 playing the role of .
+Catalysis involves the residue at position 347 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 64 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 1085 playing the role of .
+Catalysis involves the residue at position 87 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 222 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 260 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 548 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 443 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 401 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 408 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 260 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 583 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 757 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1359 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1542 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2009 playing the role of For methyltransferase activity.
+Catalysis involves the residue at position 160 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 380 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 339 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 495 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 648 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 254 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 269 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1204 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 553 playing the role of Charge relay system.
+Catalysis involves the residue at position 331 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 454 playing the role of Charge relay system.
+Catalysis involves the residue at position 578 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 177 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 190 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 97 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 371 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 682 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1011 playing the role of For beta-hydroxyacyl dehydratase activity.
+Catalysis involves the residue at position 515 playing the role of Proton donor.
+Catalysis involves the residue at position 700 playing the role of For beta-ketoacyl synthase 1 activity.
+Catalysis involves the residue at position 1680 playing the role of For beta-ketoacyl synthase 2 activity.
+Catalysis involves the residue at position 1815 playing the role of For beta-ketoacyl synthase 2 activity.
+Catalysis involves the residue at position 1862 playing the role of For beta-ketoacyl synthase 2 activity.
+Catalysis involves the residue at position 135 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 88 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 237 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 410 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 533 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 197 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 516 playing the role of Proton acceptor.
+Catalysis involves the residue at position 358 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 570 playing the role of Charge relay system.
+Catalysis involves the residue at position 689 playing the role of Charge relay system.
+Catalysis involves the residue at position 542 playing the role of Proton acceptor.
+Catalysis involves the residue at position 233 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 80 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 260 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 844 playing the role of Proton acceptor.
+Catalysis involves the residue at position 71 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 379 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 1028 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 238 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 92 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 86 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 185 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 15 playing the role of Proton acceptor; for FBP phosphatase activity.
+Catalysis involves the residue at position 237 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 240 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.
+Catalysis involves the residue at position 432 playing the role of Proton acceptor.
+Catalysis involves the residue at position 149 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 227 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 409 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 144 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 455 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 30 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 312 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 511 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 375 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 81 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 61 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 363 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 67 playing the role of Proton acceptor; for cyclase activity.
+Catalysis involves the residue at position 69 playing the role of Proton donor; for cyclase activity.
+Catalysis involves the residue at position 82 playing the role of Proton donor; for cyclase activity.
+Catalysis involves the residue at position 405 playing the role of Proton acceptor; for methyltransferase activity.
+Catalysis involves the residue at position 249 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 11 playing the role of Nucleophile; cysteine thioarsenate intermediate.
+Catalysis involves the residue at position 485 playing the role of Nucleophile.
+Catalysis involves the residue at position 634 playing the role of .
+Catalysis involves the residue at position 1234 playing the role of Proton acceptor.
+Catalysis involves the residue at position 974 playing the role of Nucleophile.
+Catalysis involves the residue at position 639 playing the role of Proton donor.
+Catalysis involves the residue at position 464 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 585 playing the role of .
+Catalysis involves the residue at position 651 playing the role of Proton donor.
+Catalysis involves the residue at position 823 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 243 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 109 playing the role of Tryptophylquinone 6'-substrate hemiaminal intermediate.
+Catalysis involves the residue at position 46 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 46 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 403 playing the role of For GATase activity.
+Catalysis involves the residue at position 532 playing the role of For GATase activity.
+Catalysis involves the residue at position 534 playing the role of For GATase activity.
+Catalysis involves the residue at position 378 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 542 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 307 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 996 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1336 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1525 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 971 playing the role of Proton acceptor.
+Catalysis involves the residue at position 730 playing the role of Proton acceptor.
+Catalysis involves the residue at position 586 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 764 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1375 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1564 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 806 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 337 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 604 playing the role of Nucleophile.
+Catalysis involves the residue at position 152 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 644 playing the role of Proton donor.
+Catalysis involves the residue at position 711 playing the role of Proton acceptor.
+Catalysis involves the residue at position 96 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 181 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 238 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 344 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 344 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 167 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 548 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 857 playing the role of Proton acceptor.
+Catalysis involves the residue at position 63 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 170 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 260 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 845 playing the role of .
+Catalysis involves the residue at position 839 playing the role of Proton acceptor.
+Catalysis involves the residue at position 641 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 968 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1132 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 196 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 551 playing the role of Charge relay system.
+Catalysis involves the residue at position 744 playing the role of Charge relay system.
+Catalysis involves the residue at position 877 playing the role of Charge relay system.
+Catalysis involves the residue at position 953 playing the role of Charge relay system.
+Catalysis involves the residue at position 1049 playing the role of Proton donor.
+Catalysis involves the residue at position 379 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 757 playing the role of Charge relay system.
+Catalysis involves the residue at position 72 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 702 playing the role of Charge relay system.
+Catalysis involves the residue at position 1242 playing the role of Nucleophile.
+Catalysis involves the residue at position 1360 playing the role of Proton acceptor.
+Catalysis involves the residue at position 52 playing the role of Proton donor; for beta-elimination activity.
+Catalysis involves the residue at position 513 playing the role of Proton acceptor.
+Catalysis involves the residue at position 373 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 81 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 568 playing the role of Charge relay system.
+Catalysis involves the residue at position 143 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 612 playing the role of .
+Catalysis involves the residue at position 235 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 299 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 459 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1056 playing the role of .
+Catalysis involves the residue at position 1099 playing the role of .
+Catalysis involves the residue at position 283 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 766 playing the role of Proton acceptor.
+Catalysis involves the residue at position 514 playing the role of Nucleophile; for isomaltase activity.
+Catalysis involves the residue at position 615 playing the role of For isomaltase activity.
+Catalysis involves the residue at position 1399 playing the role of Nucleophile; for sucrase activity.
+Catalysis involves the residue at position 1402 playing the role of For sucrase activity.
+Catalysis involves the residue at position 1512 playing the role of Proton donor; for sucrase activity.
+Catalysis involves the residue at position 480 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 150 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 260 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 858 playing the role of Proton donor.
+Catalysis involves the residue at position 1333 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1522 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 337 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 358 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 129 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 456 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 355 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 404 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 73 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 144 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 149 playing the role of For ring-opening step.
+Catalysis involves the residue at position 541 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 676 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1325 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1857 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 224 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 359 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 398 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 701 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1051 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1241 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 425 playing the role of Charge relay system.
+Catalysis involves the residue at position 480 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 378 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 294 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 307 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 408 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 531 playing the role of Charge relay system.
+Catalysis involves the residue at position 88 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 180 playing the role of For GATase activity.
+Catalysis involves the residue at position 434 playing the role of Nucleophile.
+Catalysis involves the residue at position 564 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 522 playing the role of Proton donor.
+Catalysis involves the residue at position 409 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 430 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 1275 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 629 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 952 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1144 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 301 playing the role of Proton donor.
+Catalysis involves the residue at position 1173 playing the role of Proton acceptor.
+Catalysis involves the residue at position 89 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 213 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 487 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 341 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 343 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 1009 playing the role of Proton acceptor.
+Catalysis involves the residue at position 124 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 129 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 152 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 561 playing the role of Proton acceptor.
+Catalysis involves the residue at position 292 playing the role of For protease activity.
+Catalysis involves the residue at position 619 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 357 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 147 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 518 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 153 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 584 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 720 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 763 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1370 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1559 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 860 playing the role of Proton acceptor.
+Catalysis involves the residue at position 87 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 196 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 138 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 425 playing the role of Proton acceptor.
+Catalysis involves the residue at position 487 playing the role of Stabilizes transition state or protonates leaving group.
+Catalysis involves the residue at position 724 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1264 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 332 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 261 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1272 playing the role of Nucleophile.
+Catalysis involves the residue at position 635 playing the role of Charge relay system.
+Catalysis involves the residue at position 987 playing the role of .
+Catalysis involves the residue at position 299 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 166 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 424 playing the role of Nucleophile; for NAALADase activity.
+Catalysis involves the residue at position 628 playing the role of Charge relay system.
+Catalysis involves the residue at position 573 playing the role of Proton acceptor.
+Catalysis involves the residue at position 104 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 749 playing the role of .
+Catalysis involves the residue at position 154 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 272 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 573 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 708 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 749 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1371 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1555 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 442 playing the role of Nucleophile.
+Catalysis involves the residue at position 499 playing the role of For protease activity; shared with dimeric partner.
+Catalysis involves the residue at position 231 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 633 playing the role of Charge relay system.
+Catalysis involves the residue at position 528 playing the role of Nucleophile.
+Catalysis involves the residue at position 564 playing the role of Proton donor.
+Catalysis involves the residue at position 467 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 336 playing the role of Proton donor.
+Catalysis involves the residue at position 614 playing the role of Proton acceptor.
+Catalysis involves the residue at position 586 playing the role of .
+Catalysis involves the residue at position 153 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 614 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 287 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 552 playing the role of Charge relay system.
+Catalysis involves the residue at position 879 playing the role of .
+Catalysis involves the residue at position 350 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 268 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1730 playing the role of .
+Catalysis involves the residue at position 46 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 1328 playing the role of Proton acceptor.
+Catalysis involves the residue at position 939 playing the role of Charge relay system.
+Catalysis involves the residue at position 1035 playing the role of Proton donor.
+Catalysis involves the residue at position 191 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1448 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 750 playing the role of Charge relay system.
+Catalysis involves the residue at position 793 playing the role of Charge relay system.
+Catalysis involves the residue at position 294 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 347 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 84 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 844 playing the role of .
+Catalysis involves the residue at position 887 playing the role of .
+Catalysis involves the residue at position 387 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 789 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 121 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 148 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 461 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 726 playing the role of Proton donor.
+Catalysis involves the residue at position 258 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 606 playing the role of For molybdenum cofactor biosynthesis protein C activity.
+Catalysis involves the residue at position 1142 playing the role of .
+Catalysis involves the residue at position 574 playing the role of .
+Catalysis involves the residue at position 572 playing the role of .
+Catalysis involves the residue at position 278 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 59 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 336 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 376 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 981 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1145 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 149 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 629 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 620 playing the role of Nucleophile.
+Catalysis involves the residue at position 480 playing the role of Nucleophile.
+Catalysis involves the residue at position 550 playing the role of Proton donor.
+Catalysis involves the residue at position 173 playing the role of Proton relay.
+Catalysis involves the residue at position 200 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 476 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 433 playing the role of Nucleophile.
+Catalysis involves the residue at position 75 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 586 playing the role of Nucleophile.
+Catalysis involves the residue at position 1280 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 822 playing the role of Proton acceptor.
+Catalysis involves the residue at position 69 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 245 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 121 playing the role of Proton donors.
+Catalysis involves the residue at position 1392 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 56 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 311 playing the role of Proton donor.
+Catalysis involves the residue at position 676 playing the role of Proton acceptor.
+Catalysis involves the residue at position 413 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1353 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 382 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 442 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 470 playing the role of Charge relay system.
+Catalysis involves the residue at position 484 playing the role of Charge relay system.
+Catalysis involves the residue at position 1607 playing the role of Proton acceptor.
+Catalysis involves the residue at position 972 playing the role of Charge relay system.
+Catalysis involves the residue at position 1048 playing the role of Charge relay system.
+Catalysis involves the residue at position 1146 playing the role of Proton donor.
+Catalysis involves the residue at position 463 playing the role of Nucleophile.
+Catalysis involves the residue at position 536 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 671 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 710 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1309 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1495 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 97 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 440 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 371 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 177 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 288 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1038 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 74 playing the role of Redox-active.
+Catalysis involves the residue at position 77 playing the role of Redox-active.
+Catalysis involves the residue at position 16 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 218 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 390 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 402 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 14 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 713 playing the role of .
+Catalysis involves the residue at position 453 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 115 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1195 playing the role of .
+Catalysis involves the residue at position 1220 playing the role of .
+Catalysis involves the residue at position 1234 playing the role of .
+Catalysis involves the residue at position 556 playing the role of Charge relay system.
+Catalysis involves the residue at position 423 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 386 playing the role of Proton donor.
+Catalysis involves the residue at position 68 playing the role of Proton donor; for OHCU decarboxylase activity.
+Catalysis involves the residue at position 183 playing the role of Charge relay system; for urate oxidase activity.
+Catalysis involves the residue at position 243 playing the role of Charge relay system; for urate oxidase activity.
+Catalysis involves the residue at position 714 playing the role of Proton donor.
+Catalysis involves the residue at position 83 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 174 playing the role of For GATase activity.
+Catalysis involves the residue at position 218 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 429 playing the role of Nucleophile.
+Catalysis involves the residue at position 56 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 401 playing the role of Proton donor.
+Catalysis involves the residue at position 518 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 257 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 953 playing the role of For nuclease activity.
+Catalysis involves the residue at position 901 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1110 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 530 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 211 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 597 playing the role of Nucleophile.
+Catalysis involves the residue at position 401 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 188 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1 playing the role of .
+Catalysis involves the residue at position 200 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 852 playing the role of .
+Catalysis involves the residue at position 854 playing the role of .
+Catalysis involves the residue at position 859 playing the role of .
+Catalysis involves the residue at position 71 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 95 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 603 playing the role of Proton acceptor.
+Catalysis involves the residue at position 474 playing the role of Charge relay system.
+Catalysis involves the residue at position 55 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 194 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 184 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 296 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 200 playing the role of Proton donors.
+Catalysis involves the residue at position 324 playing the role of Pros-phosphohistidine intermediate; for HPr activity.
+Catalysis involves the residue at position 238 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 454 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 112 playing the role of Charge relay.
+Catalysis involves the residue at position 389 playing the role of Charge relay system.
+Catalysis involves the residue at position 594 playing the role of Charge relay system.
+Catalysis involves the residue at position 4 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 455 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 1135 playing the role of Proton acceptor.
+Catalysis involves the residue at position 122 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 213 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 925 playing the role of .
+Catalysis involves the residue at position 970 playing the role of .
+Catalysis involves the residue at position 360 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 17 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 582 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 85 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 986 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 329 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 116 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 1223 playing the role of .
+Catalysis involves the residue at position 329 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 48 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 938 playing the role of Proton donor.
+Catalysis involves the residue at position 416 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 608 playing the role of .
+Catalysis involves the residue at position 88 playing the role of For GATase activity.
+Catalysis involves the residue at position 177 playing the role of For GATase activity.
+Catalysis involves the residue at position 314 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 507 playing the role of Proton acceptor.
+Catalysis involves the residue at position 552 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 731 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1321 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 585 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 45 playing the role of Redox-active.
+Catalysis involves the residue at position 1081 playing the role of For nuclease activity.
+Catalysis involves the residue at position 82 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 151 playing the role of For ring-opening step.
+Catalysis involves the residue at position 153 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 158 playing the role of For ring-opening step.
+Catalysis involves the residue at position 161 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 1388 playing the role of Proton acceptor.
+Catalysis involves the residue at position 285 playing the role of Charge relay system.
+Catalysis involves the residue at position 505 playing the role of Proton acceptor.
+Catalysis involves the residue at position 25 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 585 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 791 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 926 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 967 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 350 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1495 playing the role of Charge relay system.
+Catalysis involves the residue at position 1544 playing the role of Charge relay system.
+Catalysis involves the residue at position 1642 playing the role of Charge relay system.
+Catalysis involves the residue at position 106 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 350 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 816 playing the role of Proton acceptor.
+Catalysis involves the residue at position 759 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 298 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 237 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 521 playing the role of Nucleophile.
+Catalysis involves the residue at position 215 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 628 playing the role of Nucleophile.
+Catalysis involves the residue at position 657 playing the role of Proton donor.
+Catalysis involves the residue at position 847 playing the role of Proton donor.
+Catalysis involves the residue at position 207 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 278 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 353 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 41 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 615 playing the role of Proton donor.
+Catalysis involves the residue at position 184 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 302 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 596 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 772 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1069 playing the role of Proton acceptor.
+Catalysis involves the residue at position 153 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 451 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 78 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 128 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 231 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 245 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 1386 playing the role of Proton acceptor.
+Catalysis involves the residue at position 216 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 595 playing the role of Proton acceptor.
+Catalysis involves the residue at position 713 playing the role of Proton donor.
+Catalysis involves the residue at position 892 playing the role of .
+Catalysis involves the residue at position 392 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 477 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 294 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 80 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 402 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 1265 playing the role of Proton donor.
+Catalysis involves the residue at position 770 playing the role of Proton acceptor.
+Catalysis involves the residue at position 22 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 193 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 409 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 217 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 245 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 1363 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 205 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 660 playing the role of .
+Catalysis involves the residue at position 213 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 287 playing the role of Charge relay system.
+Catalysis involves the residue at position 517 playing the role of Charge relay system.
+Catalysis involves the residue at position 375 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 117 playing the role of Electrophile.
+Catalysis involves the residue at position 156 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 759 playing the role of Proton acceptor.
+Catalysis involves the residue at position 306 playing the role of Proton donor.
+Catalysis involves the residue at position 207 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 839 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 666 playing the role of Proton donor.
+Catalysis involves the residue at position 233 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 242 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1084 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 259 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 667 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 193 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 323 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 120 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 452 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 826 playing the role of .
+Catalysis involves the residue at position 431 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 725 playing the role of Proton acceptor.
+Catalysis involves the residue at position 599 playing the role of Nucleophile.
+Catalysis involves the residue at position 1923 playing the role of Proton acceptor.
+Catalysis involves the residue at position 619 playing the role of Proton donor.
+Catalysis involves the residue at position 199 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 229 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 408 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 397 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 404 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 565 playing the role of Proton donor.
+Catalysis involves the residue at position 567 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 282 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 17 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 435 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 486 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 351 playing the role of Nucleophile.
+Catalysis involves the residue at position 996 playing the role of Proton acceptor.
+Catalysis involves the residue at position 304 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 780 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 229 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 250 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 114 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 492 playing the role of Nucleophile.
+Catalysis involves the residue at position 237 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 806 playing the role of Proton acceptor.
+Catalysis involves the residue at position 388 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 1447 playing the role of .
+Catalysis involves the residue at position 98 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 1034 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 968 playing the role of Nucleophile.
+Catalysis involves the residue at position 321 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 437 playing the role of Charge relay system.
+Catalysis involves the residue at position 543 playing the role of Charge relay system.
+Catalysis involves the residue at position 366 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 232 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 37 playing the role of For GATase activity.
+Catalysis involves the residue at position 170 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 432 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 522 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 439 playing the role of Proton donor.
+Catalysis involves the residue at position 332 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 546 playing the role of Proton donor.
+Catalysis involves the residue at position 1002 playing the role of Proton acceptor.
+Catalysis involves the residue at position 349 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 370 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 120 playing the role of Schiff-base intermediate with acetoacetate.
+Catalysis involves the residue at position 580 playing the role of Charge relay system.
+Catalysis involves the residue at position 460 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 322 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 362 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 600 playing the role of Nucleophile.
+Catalysis involves the residue at position 309 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 517 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 323 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 978 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1163 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 280 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 285 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 505 playing the role of Charge relay system.
+Catalysis involves the residue at position 321 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 773 playing the role of .
+Catalysis involves the residue at position 1455 playing the role of Nucleophile.
+Catalysis involves the residue at position 1573 playing the role of Proton acceptor.
+Catalysis involves the residue at position 203 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 350 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 1268 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 189 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 530 playing the role of Nucleophile.
+Catalysis involves the residue at position 125 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 229 playing the role of Nucleophile or transition state stabilizer.
+Catalysis involves the residue at position 503 playing the role of Nucleophile.
+Catalysis involves the residue at position 297 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 343 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 176 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 486 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 473 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 385 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 936 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 538 playing the role of Charge relay system.
+Catalysis involves the residue at position 315 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 552 playing the role of .
+Catalysis involves the residue at position 397 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 133 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 474 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 609 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 650 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1245 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1434 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 258 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 453 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 586 playing the role of Proton donor.
+Catalysis involves the residue at position 1142 playing the role of Nucleophile.
+Catalysis involves the residue at position 1267 playing the role of .
+Catalysis involves the residue at position 1269 playing the role of .
+Catalysis involves the residue at position 137 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 533 playing the role of Proton acceptor.
+Catalysis involves the residue at position 191 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 357 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 778 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 908 playing the role of Proton acceptor.
+Catalysis involves the residue at position 131 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 296 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 389 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 410 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 488 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 623 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 667 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1262 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1452 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 159 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 373 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 488 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 488 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 462 playing the role of Nucleophile.
+Catalysis involves the residue at position 250 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 414 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 449 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 533 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 112 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 840 playing the role of Proton acceptor.
+Catalysis involves the residue at position 550 playing the role of Charge relay system.
+Catalysis involves the residue at position 181 playing the role of Pros-phosphohistidine intermediate; for EIIB activity.
+Catalysis involves the residue at position 418 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 206 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 421 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 427 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 76 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 214 playing the role of Proton donors.
+Catalysis involves the residue at position 114 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 405 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1959 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 769 playing the role of .
+Catalysis involves the residue at position 107 playing the role of Phosphothreonine intermediate.
+Catalysis involves the residue at position 99 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 954 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1683 playing the role of Proton acceptor.
+Catalysis involves the residue at position 840 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 73 playing the role of Proton acceptor/donor.
+Catalysis involves the residue at position 572 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 751 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1357 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1545 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 94 playing the role of For GATase activity.
+Catalysis involves the residue at position 428 playing the role of Proton donor.
+Catalysis involves the residue at position 425 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 781 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1000 playing the role of Nucleophile.
+Catalysis involves the residue at position 1120 playing the role of Proton acceptor.
+Catalysis involves the residue at position 334 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 186 playing the role of For GATase activity.
+Catalysis involves the residue at position 188 playing the role of For GATase activity.
+Catalysis involves the residue at position 167 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 307 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 555 playing the role of Proton acceptor.
+Catalysis involves the residue at position 351 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 1045 playing the role of Proton acceptor.
+Catalysis involves the residue at position 465 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 380 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 494 playing the role of Nucleophile.
+Catalysis involves the residue at position 504 playing the role of Nucleophile.
+Catalysis involves the residue at position 554 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 689 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 734 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1528 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 664 playing the role of .
+Catalysis involves the residue at position 472 playing the role of For target RNA cleavage.
+Catalysis involves the residue at position 477 playing the role of For target RNA cleavage.
+Catalysis involves the residue at position 1048 playing the role of For target RNA cleavage.
+Catalysis involves the residue at position 1053 playing the role of For target RNA cleavage.
+Catalysis involves the residue at position 70 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 716 playing the role of .
+Catalysis involves the residue at position 403 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 550 playing the role of .
+Catalysis involves the residue at position 603 playing the role of Nucleophile.
+Catalysis involves the residue at position 545 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 680 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1329 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1519 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1875 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 194 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 333 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 990 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1170 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 834 playing the role of .
+Catalysis involves the residue at position 189 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 306 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 1015 playing the role of Proton acceptor.
+Catalysis involves the residue at position 814 playing the role of Proton acceptor.
+Catalysis involves the residue at position 761 playing the role of .
+Catalysis involves the residue at position 183 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 80 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 251 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 476 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 81 playing the role of For formimidoyltransferase activity.
+Catalysis involves the residue at position 787 playing the role of .
+Catalysis involves the residue at position 944 playing the role of .
+Catalysis involves the residue at position 373 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 124 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 133 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 180 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 299 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1589 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1880 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 219 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 661 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 205 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 9 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 599 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 117 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 541 playing the role of Proton acceptor.
+Catalysis involves the residue at position 29 playing the role of Schiff-base intermediate with DNA; for 5'-deoxyribose-5-phosphate lyase activity.
+Catalysis involves the residue at position 141 playing the role of For GATase activity.
+Catalysis involves the residue at position 246 playing the role of For GATase activity.
+Catalysis involves the residue at position 248 playing the role of For GATase activity.
+Catalysis involves the residue at position 130 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 778 playing the role of Proton donor.
+Catalysis involves the residue at position 637 playing the role of Proton donor.
+Catalysis involves the residue at position 609 playing the role of .
+Catalysis involves the residue at position 534 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 712 playing the role of Proton donor.
+Catalysis involves the residue at position 149 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 351 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 372 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 804 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 275 playing the role of N6-(4-deoxychorismate)-lysine intermediate.
+Catalysis involves the residue at position 1000 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1060 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 261 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 398 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 470 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 14 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 330 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 351 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 73 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 462 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 126 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 176 playing the role of Nucleophile and sulfur donor.
+Catalysis involves the residue at position 89 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 182 playing the role of For GATase activity.
+Catalysis involves the residue at position 184 playing the role of For GATase activity.
+Catalysis involves the residue at position 160 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 356 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 265 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 766 playing the role of .
+Catalysis involves the residue at position 844 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1217 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 124 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 578 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 280 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 332 playing the role of Charge relay system.
+Catalysis involves the residue at position 261 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 435 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1007 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1177 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 208 playing the role of For GATase activity.
+Catalysis involves the residue at position 210 playing the role of For GATase activity.
+Catalysis involves the residue at position 341 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 137 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 69 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 1192 playing the role of Nucleophile.
+Catalysis involves the residue at position 1313 playing the role of .
+Catalysis involves the residue at position 1315 playing the role of .
+Catalysis involves the residue at position 891 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 370 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 391 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 194 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 113 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 422 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 617 playing the role of Proton acceptor.
+Catalysis involves the residue at position 140 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 402 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 423 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 252 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 215 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 971 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 527 playing the role of Proton acceptor.
+Catalysis involves the residue at position 750 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 728 playing the role of Proton donor.
+Catalysis involves the residue at position 964 playing the role of Nucleophile.
+Catalysis involves the residue at position 502 playing the role of Nucleophile.
+Catalysis involves the residue at position 192 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 509 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 518 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 541 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 406 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 427 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 720 playing the role of Proton donor.
+Catalysis involves the residue at position 110 playing the role of Proton donor/acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 133 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 277 playing the role of Proton acceptor; for shikimate dehydrogenase activity.
+Catalysis involves the residue at position 373 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 171 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 325 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 529 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 907 playing the role of Proton donor.
+Catalysis involves the residue at position 624 playing the role of .
+Catalysis involves the residue at position 295 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 370 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 144 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1073 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1368 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 505 playing the role of Nucleophile; for isomaltase activity.
+Catalysis involves the residue at position 604 playing the role of For isomaltase activity.
+Catalysis involves the residue at position 1394 playing the role of Nucleophile; for sucrase activity.
+Catalysis involves the residue at position 1397 playing the role of For sucrase activity.
+Catalysis involves the residue at position 1500 playing the role of Proton donor; for isomaltase activity.
+Catalysis involves the residue at position 361 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 183 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 1183 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 629 playing the role of .
+Catalysis involves the residue at position 240 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 1290 playing the role of Proton acceptor.
+Catalysis involves the residue at position 351 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 355 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 37 playing the role of Charge relay.
+Catalysis involves the residue at position 1553 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1844 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 175 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 805 playing the role of Proton acceptor.
+Catalysis involves the residue at position 721 playing the role of Charge relay system.
+Catalysis involves the residue at position 203 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 232 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 818 playing the role of .
+Catalysis involves the residue at position 856 playing the role of .
+Catalysis involves the residue at position 888 playing the role of .
+Catalysis involves the residue at position 1021 playing the role of .
+Catalysis involves the residue at position 146 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 463 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 792 playing the role of Charge relay system.
+Catalysis involves the residue at position 926 playing the role of Charge relay system.
+Catalysis involves the residue at position 1002 playing the role of Charge relay system.
+Catalysis involves the residue at position 1098 playing the role of Proton donor.
+Catalysis involves the residue at position 90 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 1252 playing the role of Nucleophile.
+Catalysis involves the residue at position 1370 playing the role of Proton acceptor.
+Catalysis involves the residue at position 311 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 222 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 895 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1393 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1366 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 764 playing the role of Proton donor.
+Catalysis involves the residue at position 494 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 194 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 378 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 195 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 508 playing the role of Proton donor.
+Catalysis involves the residue at position 192 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 438 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 733 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 265 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 258 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 426 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 289 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 630 playing the role of Proton acceptor.
+Catalysis involves the residue at position 373 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 538 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 673 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 982 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1295 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1481 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 342 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 363 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 787 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 280 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 280 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 333 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 1193 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 102 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 197 playing the role of For GATase activity.
+Catalysis involves the residue at position 237 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 143 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 246 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 246 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 825 playing the role of Charge relay system.
+Catalysis involves the residue at position 876 playing the role of Charge relay system.
+Catalysis involves the residue at position 971 playing the role of Charge relay system.
+Catalysis involves the residue at position 338 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 448 playing the role of Nucleophile.
+Catalysis involves the residue at position 179 playing the role of For GATase activity.
+Catalysis involves the residue at position 403 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 558 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 558 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 156 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 397 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 74 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 135 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 237 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 237 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 405 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 510 playing the role of For hydroxyacyl-coenzyme A dehydrogenase activity.
+Catalysis involves the residue at position 199 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 38 playing the role of Proton acceptor; for 5-exo epoxide-opening cyclization activity.
+Catalysis involves the residue at position 170 playing the role of Proton acceptor; for 6-endo epoxide-opening cyclization activity.
+Catalysis involves the residue at position 979 playing the role of Proton acceptor.
+Catalysis involves the residue at position 736 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1008 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1338 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 965 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 310 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 844 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 69 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 791 playing the role of Proton acceptor.
+Catalysis involves the residue at position 83 playing the role of For GATase activity.
+Catalysis involves the residue at position 193 playing the role of For GATase activity.
+Catalysis involves the residue at position 195 playing the role of For GATase activity.
+Catalysis involves the residue at position 110 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 431 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 690 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 436 playing the role of Proton donor.
+Catalysis involves the residue at position 208 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 549 playing the role of Nucleophile.
+Catalysis involves the residue at position 136 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 446 playing the role of Nucleophile.
+Catalysis involves the residue at position 271 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 1009 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1339 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 195 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 284 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 59 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1170 playing the role of Nucleophile.
+Catalysis involves the residue at position 1288 playing the role of Proton acceptor.
+Catalysis involves the residue at position 600 playing the role of Proton donor.
+Catalysis involves the residue at position 705 playing the role of Nucleophile.
+Catalysis involves the residue at position 237 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 819 playing the role of Nucleophile.
+Catalysis involves the residue at position 626 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 391 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 737 playing the role of Proton donor.
+Catalysis involves the residue at position 383 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 404 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 385 playing the role of For GATase activity.
+Catalysis involves the residue at position 509 playing the role of For GATase activity.
+Catalysis involves the residue at position 511 playing the role of For GATase activity.
+Catalysis involves the residue at position 300 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 669 playing the role of Proton donor.
+Catalysis involves the residue at position 221 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 685 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1014 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1195 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 95 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 1249 playing the role of Proton acceptor.
+Catalysis involves the residue at position 150 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 223 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 416 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 159 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 166 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 99 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 433 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 151 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 1037 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 732 playing the role of Proton donor.
+Catalysis involves the residue at position 808 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1015 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 578 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1030 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1358 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1987 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 1260 playing the role of Proton acceptor.
+Catalysis involves the residue at position 607 playing the role of Proton acceptor.
+Catalysis involves the residue at position 194 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 460 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 548 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 207 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 92 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 68 playing the role of Nucleophile; for acetylxylan esterase activity.
+Catalysis involves the residue at position 240 playing the role of For acetylxylan esterase activity.
+Catalysis involves the residue at position 243 playing the role of For acetylxylan esterase activity.
+Catalysis involves the residue at position 565 playing the role of Nucleophile; for glucuronoyl esterase activity.
+Catalysis involves the residue at position 93 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 228 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 355 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 376 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 1203 playing the role of Proton acceptor.
+Catalysis involves the residue at position 175 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 589 playing the role of Proton acceptor.
+Catalysis involves the residue at position 204 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 367 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 393 playing the role of Proton donor.
+Catalysis involves the residue at position 86 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 223 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 911 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 669 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 481 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 485 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 64 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 738 playing the role of Proton acceptor.
+Catalysis involves the residue at position 437 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 764 playing the role of Charge relay system.
+Catalysis involves the residue at position 863 playing the role of Proton donor.
+Catalysis involves the residue at position 435 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 71 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 155 playing the role of For GATase activity.
+Catalysis involves the residue at position 157 playing the role of For GATase activity.
+Catalysis involves the residue at position 534 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 670 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 992 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 506 playing the role of Proton acceptor.
+Catalysis involves the residue at position 910 playing the role of .
+Catalysis involves the residue at position 686 playing the role of Nucleophile.
+Catalysis involves the residue at position 1633 playing the role of Proton acceptor.
+Catalysis involves the residue at position 579 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 715 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 758 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 283 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 976 playing the role of Proton acceptor.
+Catalysis involves the residue at position 134 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 160 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 274 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 741 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1291 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1471 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 433 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 469 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 759 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 660 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 959 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 135 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 172 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 21 playing the role of Charge relay system.
+Catalysis involves the residue at position 431 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 301 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 1824 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 36 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 12 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 438 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 622 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 1519 playing the role of Proton acceptor.
+Catalysis involves the residue at position 852 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 738 playing the role of Nucleophile.
+Catalysis involves the residue at position 342 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 286 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 232 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 205 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 86 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1036 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 397 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 303 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 832 playing the role of .
+Catalysis involves the residue at position 419 playing the role of S-acetylcysteine intermediate.
+Catalysis involves the residue at position 420 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 175 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 669 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1166 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 263 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 762 playing the role of Proton acceptor.
+Catalysis involves the residue at position 593 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 653 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 522 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 413 playing the role of Charge relay system.
+Catalysis involves the residue at position 457 playing the role of Nucleophile.
+Catalysis involves the residue at position 510 playing the role of Proton donor.
+Catalysis involves the residue at position 469 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 171 playing the role of Pros-phosphohistidine intermediate; for HPr activity.
+Catalysis involves the residue at position 457 playing the role of Tele-phosphohistidine intermediate; for PTS EI activity.
+Catalysis involves the residue at position 197 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 355 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 926 playing the role of .
+Catalysis involves the residue at position 1021 playing the role of Proton acceptor.
+Catalysis involves the residue at position 86 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 597 playing the role of Charge relay system.
+Catalysis involves the residue at position 551 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 96 playing the role of For GATase activity.
+Catalysis involves the residue at position 189 playing the role of For GATase activity.
+Catalysis involves the residue at position 191 playing the role of For GATase activity.
+Catalysis involves the residue at position 230 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 108 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 1032 playing the role of .
+Catalysis involves the residue at position 1075 playing the role of .
+Catalysis involves the residue at position 221 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 275 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 854 playing the role of Proton acceptor.
+Catalysis involves the residue at position 123 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1110 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 651 playing the role of Charge relay system.
+Catalysis involves the residue at position 494 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 194 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 238 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 396 playing the role of Proton acceptor.
+Catalysis involves the residue at position 2029 playing the role of .
+Catalysis involves the residue at position 481 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 703 playing the role of Charge relay system.
+Catalysis involves the residue at position 252 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 116 playing the role of Nucleophile; for endoxylanase activity.
+Catalysis involves the residue at position 213 playing the role of Proton donor; for endoxylanase activity.
+Catalysis involves the residue at position 736 playing the role of Proton acceptor.
+Catalysis involves the residue at position 340 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 342 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 292 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 639 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 506 playing the role of Nucleophile.
+Catalysis involves the residue at position 1165 playing the role of Proton acceptor.
+Catalysis involves the residue at position 784 playing the role of Proton donor.
+Catalysis involves the residue at position 782 playing the role of Proton acceptor.
+Catalysis involves the residue at position 372 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 763 playing the role of Nucleophile.
+Catalysis involves the residue at position 792 playing the role of Proton donor.
+Catalysis involves the residue at position 311 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 313 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 316 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 257 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 314 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 317 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 945 playing the role of .
+Catalysis involves the residue at position 1014 playing the role of .
+Catalysis involves the residue at position 1189 playing the role of .
+Catalysis involves the residue at position 133 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 27 playing the role of For GATase activity.
+Catalysis involves the residue at position 469 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 897 playing the role of .
+Catalysis involves the residue at position 899 playing the role of .
+Catalysis involves the residue at position 904 playing the role of .
+Catalysis involves the residue at position 472 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 146 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 281 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 900 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1065 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 235 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 412 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 700 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1020 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1202 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 337 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 156 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 223 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 130 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 87 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 101 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 196 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 139 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 452 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 374 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 395 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 341 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 652 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 123 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 800 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 809 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 860 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 908 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 993 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 1226 playing the role of For DNase activity of nuclease domain.
+Catalysis involves the residue at position 1263 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 238 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 107 playing the role of Charge relay.
+Catalysis involves the residue at position 161 playing the role of Proton donor; for xylanase activity.
+Catalysis involves the residue at position 280 playing the role of Nucleophile; for xylanase activity.
+Catalysis involves the residue at position 629 playing the role of Nucleophile; for esterase activity.
+Catalysis involves the residue at position 1005 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 932 playing the role of Proton acceptor.
+Catalysis involves the residue at position 116 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 42 playing the role of Proton acceptor (ATPase activity).
+Catalysis involves the residue at position 587 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 105 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 620 playing the role of .
+Catalysis involves the residue at position 444 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 759 playing the role of Proton donor.
+Catalysis involves the residue at position 74 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 1202 playing the role of Proton acceptor.
+Catalysis involves the residue at position 319 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 451 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 132 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 289 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1262 playing the role of Proton acceptor.
+Catalysis involves the residue at position 484 playing the role of Nucleophile.
+Catalysis involves the residue at position 402 playing the role of For GATase activity.
+Catalysis involves the residue at position 531 playing the role of For GATase activity.
+Catalysis involves the residue at position 533 playing the role of For GATase activity.
+Catalysis involves the residue at position 139 playing the role of For ring-opening step.
+Catalysis involves the residue at position 141 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 146 playing the role of For ring-opening step.
+Catalysis involves the residue at position 192 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 205 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 853 playing the role of Nucleophile.
+Catalysis involves the residue at position 64 playing the role of For deubiquitinase activity.
+Catalysis involves the residue at position 80 playing the role of For deubiquitinase activity.
+Catalysis involves the residue at position 117 playing the role of Nucleophile; for deubiquitinase activity.
+Catalysis involves the residue at position 414 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1466 playing the role of Proton acceptor.
+Catalysis involves the residue at position 149 playing the role of Nucleophile; for glutaminase activity.
+Catalysis involves the residue at position 246 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 814 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 505 playing the role of Nucleophile.
+Catalysis involves the residue at position 983 playing the role of .
+Catalysis involves the residue at position 1026 playing the role of .
+Catalysis involves the residue at position 489 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 1187 playing the role of Nucleophile.
+Catalysis involves the residue at position 1319 playing the role of .
+Catalysis involves the residue at position 1321 playing the role of .
+Catalysis involves the residue at position 209 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 162 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 123 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 141 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 479 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 416 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 823 playing the role of Charge relay system.
+Catalysis involves the residue at position 856 playing the role of Charge relay system.
+Catalysis involves the residue at position 314 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 160 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 903 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 485 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 278 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 538 playing the role of Proton donor.
+Catalysis involves the residue at position 635 playing the role of Nucleophile.
+Catalysis involves the residue at position 907 playing the role of Proton acceptor.
+Catalysis involves the residue at position 159 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 499 playing the role of Proton acceptor.
+Catalysis involves the residue at position 119 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 141 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1197 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1416 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1457 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 985 playing the role of For poly [ADP-ribose] polymerase activity.
+Catalysis involves the residue at position 568 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 670 playing the role of Proton donor.
+Catalysis involves the residue at position 268 playing the role of Proton acceptor; for AICAR formyltransferase activity.
+Catalysis involves the residue at position 208 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 389 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 220 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 848 playing the role of .
+Catalysis involves the residue at position 227 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 1130 playing the role of Proton acceptor.
+Catalysis involves the residue at position 919 playing the role of Proton acceptor.
+Catalysis involves the residue at position 66 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 555 playing the role of Nucleophile.
+Catalysis involves the residue at position 648 playing the role of Proton donor.
+Catalysis involves the residue at position 1276 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 788 playing the role of .
+Catalysis involves the residue at position 1067 playing the role of Proton donor; for phlorizin hydrolase/Glycosylceramidase activity.
+Catalysis involves the residue at position 1274 playing the role of Nucleophile; for phlorizin hydrolase/Glycosylceramidase activity.
+Catalysis involves the residue at position 1539 playing the role of Proton donor; for lactase activity.
+Catalysis involves the residue at position 1750 playing the role of Nucleophile; for lactase activity.
+Catalysis involves the residue at position 769 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 825 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 912 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 912 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 254 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 323 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 906 playing the role of Proton acceptor.
+Catalysis involves the residue at position 155 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 66 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 36 playing the role of Charge relay system.
+Catalysis involves the residue at position 631 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 185 playing the role of Acyl-thioester intermediate; for beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 634 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 938 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1108 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 162 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 140 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 179 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 669 playing the role of Charge relay system.
+Catalysis involves the residue at position 742 playing the role of Charge relay system.
+Catalysis involves the residue at position 774 playing the role of Charge relay system.
+Catalysis involves the residue at position 255 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 609 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 425 playing the role of Nucleophile.
+Catalysis involves the residue at position 1120 playing the role of .
+Catalysis involves the residue at position 1147 playing the role of .
+Catalysis involves the residue at position 1247 playing the role of .
+Catalysis involves the residue at position 719 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 988 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1512 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2002 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 168 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 1268 playing the role of Nucleophile.
+Catalysis involves the residue at position 319 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 580 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 243 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 276 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 530 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 665 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 974 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1443 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2194 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 298 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 202 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 17 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 917 playing the role of Proton acceptor.
+Catalysis involves the residue at position 97 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 119 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 230 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 395 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 251 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 218 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 344 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 236 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 299 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 58 playing the role of Proton donor; for OHCU decarboxylase activity.
+Catalysis involves the residue at position 218 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 1572 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1043 playing the role of Proton acceptor.
+Catalysis involves the residue at position 551 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 503 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 117 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 707 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 516 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 91 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 245 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 767 playing the role of Charge relay system.
+Catalysis involves the residue at position 866 playing the role of Proton donor.
+Catalysis involves the residue at position 743 playing the role of Nucleophile.
+Catalysis involves the residue at position 1526 playing the role of Proton acceptor.
+Catalysis involves the residue at position 86 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 154 playing the role of For ring-opening step.
+Catalysis involves the residue at position 156 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 161 playing the role of For ring-opening step.
+Catalysis involves the residue at position 106 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 2072 playing the role of Proton acceptor.
+Catalysis involves the residue at position 714 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 70 playing the role of Proton donor; for OHCU decarboxylase activity.
+Catalysis involves the residue at position 794 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 181 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 84 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 259 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 268 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 435 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 404 playing the role of Proton donor.
+Catalysis involves the residue at position 552 playing the role of For 5,10-methylenetetrahydrofolate synthesis activity.
+Catalysis involves the residue at position 545 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 922 playing the role of Proton donor.
+Catalysis involves the residue at position 159 playing the role of Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity.
+Catalysis involves the residue at position 513 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 919 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 51 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 1574 playing the role of Proton acceptor.
+Catalysis involves the residue at position 90 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 104 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 1129 playing the role of Proton acceptor.
+Catalysis involves the residue at position 112 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 265 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 205 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 260 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 66 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 10 playing the role of Nucleophile; cysteine thioarsenate intermediate.
+Catalysis involves the residue at position 241 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 352 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 1516 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 632 playing the role of .
+Catalysis involves the residue at position 836 playing the role of .
+Catalysis involves the residue at position 233 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 312 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 648 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 982 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1167 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 468 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 2355 playing the role of Proton acceptor.
+Catalysis involves the residue at position 650 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1146 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 91 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 148 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 73 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 160 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 226 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 975 playing the role of Proton acceptor.
+Catalysis involves the residue at position 977 playing the role of Proton acceptor.
+Catalysis involves the residue at position 402 playing the role of Proton donor.
+Catalysis involves the residue at position 65 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 577 playing the role of .
+Catalysis involves the residue at position 194 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 1176 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 306 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 146 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 375 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 824 playing the role of Proton acceptor.
+Catalysis involves the residue at position 598 playing the role of Proton donor.
+Catalysis involves the residue at position 703 playing the role of Nucleophile.
+Catalysis involves the residue at position 450 playing the role of Proton donor.
+Catalysis involves the residue at position 150 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 354 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 432 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 144 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 287 playing the role of Acyl-thioester intermediate; for beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 423 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 463 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 801 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 1533 playing the role of For thioesterase-like activity.
+Catalysis involves the residue at position 21 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 1259 playing the role of Proton acceptor; for thioesterase activity.
+Catalysis involves the residue at position 296 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 327 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 455 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 847 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 709 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 262 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 327 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 833 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 314 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 91 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 370 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 130 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 415 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 549 playing the role of Proton donor.
+Catalysis involves the residue at position 1847 playing the role of Proton acceptor.
+Catalysis involves the residue at position 722 playing the role of Charge relay system.
+Catalysis involves the residue at position 223 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 669 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 707 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 978 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1297 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1095 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1389 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 143 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 328 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 653 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 958 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1123 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 307 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 543 playing the role of Proton donor.
+Catalysis involves the residue at position 245 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 863 playing the role of Proton acceptor.
+Catalysis involves the residue at position 94 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 538 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 891 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 645 playing the role of Nucleophile.
+Catalysis involves the residue at position 874 playing the role of Charge relay system.
+Catalysis involves the residue at position 925 playing the role of Charge relay system.
+Catalysis involves the residue at position 1021 playing the role of Charge relay system.
+Catalysis involves the residue at position 2301 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2474 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 238 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 754 playing the role of Nucleophile.
+Catalysis involves the residue at position 514 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 893 playing the role of .
+Catalysis involves the residue at position 962 playing the role of .
+Catalysis involves the residue at position 1121 playing the role of .
+Catalysis involves the residue at position 867 playing the role of .
+Catalysis involves the residue at position 329 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 322 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 1899 playing the role of Proton acceptor.
+Catalysis involves the residue at position 623 playing the role of Nucleophile.
+Catalysis involves the residue at position 1076 playing the role of Proton acceptor.
+Catalysis involves the residue at position 301 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 731 playing the role of Proton acceptor.
+Catalysis involves the residue at position 344 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 156 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 733 playing the role of Proton acceptor.
+Catalysis involves the residue at position 30 playing the role of Proton acceptor.
+Catalysis involves the residue at position 136 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 182 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 823 playing the role of .
+Catalysis involves the residue at position 318 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 407 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1013 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1200 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 499 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 300 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 466 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 1180 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1208 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 255 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 339 playing the role of For GATase activity.
+Catalysis involves the residue at position 341 playing the role of For GATase activity.
+Catalysis involves the residue at position 198 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 500 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 570 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 683 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 683 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 474 playing the role of Nucleophile.
+Catalysis involves the residue at position 216 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 555 playing the role of Proton donor.
+Catalysis involves the residue at position 29 playing the role of Charge relay system.
+Catalysis involves the residue at position 128 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 228 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 500 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1063 playing the role of Proton acceptor.
+Catalysis involves the residue at position 613 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 599 playing the role of For molybdenum cofactor biosynthesis protein C activity.
+Catalysis involves the residue at position 495 playing the role of Electrophile.
+Catalysis involves the residue at position 115 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 760 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1070 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 370 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 651 playing the role of Proton acceptor.
+Catalysis involves the residue at position 761 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 388 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 117 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 268 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 379 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 379 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 864 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 126 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 185 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 527 playing the role of For GATase activity.
+Catalysis involves the residue at position 529 playing the role of For GATase activity.
+Catalysis involves the residue at position 266 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 261 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 1796 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 391 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 1051 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 202 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 1134 playing the role of Nucleophile.
+Catalysis involves the residue at position 1259 playing the role of .
+Catalysis involves the residue at position 361 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 402 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 331 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1069 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 735 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 515 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 196 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 638 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 178 playing the role of Acyl-thioester intermediate; for beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 626 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 931 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1097 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1855 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 368 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 544 playing the role of Nucleophile.
+Catalysis involves the residue at position 253 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 427 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1004 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 93 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 150 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 360 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 314 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1006 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1537 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 190 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 950 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 431 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 433 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 864 playing the role of .
+Catalysis involves the residue at position 896 playing the role of .
+Catalysis involves the residue at position 1029 playing the role of .
+Catalysis involves the residue at position 891 playing the role of Charge relay system.
+Catalysis involves the residue at position 986 playing the role of Charge relay system.
+Catalysis involves the residue at position 521 playing the role of Proton donor.
+Catalysis involves the residue at position 962 playing the role of Nucleophile.
+Catalysis involves the residue at position 34 playing the role of Charge relay system.
+Catalysis involves the residue at position 116 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 151 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 31 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 868 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 300 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 175 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 106 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1067 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 326 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 544 playing the role of Proton donor.
+Catalysis involves the residue at position 6 playing the role of Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity.
+Catalysis involves the residue at position 28 playing the role of For phospholipase activity.
+Catalysis involves the residue at position 152 playing the role of Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity.
+Catalysis involves the residue at position 605 playing the role of .
+Catalysis involves the residue at position 893 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 1436 playing the role of Proton acceptor.
+Catalysis involves the residue at position 283 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 191 playing the role of Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity.
+Catalysis involves the residue at position 700 playing the role of .
+Catalysis involves the residue at position 304 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 370 playing the role of For cyclooxygenase activity.
+Catalysis involves the residue at position 955 playing the role of Proton acceptor.
+Catalysis involves the residue at position 659 playing the role of Proton acceptor.
+Catalysis involves the residue at position 979 playing the role of Nucleophile.
+Catalysis involves the residue at position 713 playing the role of Proton acceptor.
+Catalysis involves the residue at position 277 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 389 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 164 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1 playing the role of For GATase activity.
+Catalysis involves the residue at position 71 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 860 playing the role of Proton donor.
+Catalysis involves the residue at position 239 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 354 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 185 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 166 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 400 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 132 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 725 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 527 playing the role of Charge relay system.
+Catalysis involves the residue at position 634 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 181 playing the role of Glycyl persulfide ester intermediate.
+Catalysis involves the residue at position 831 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 441 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 626 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 466 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 1350 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 750 playing the role of .
+Catalysis involves the residue at position 583 playing the role of For coproheme decarboxylase activity.
+Catalysis involves the residue at position 1020 playing the role of Proton acceptor.
+Catalysis involves the residue at position 153 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 861 playing the role of Proton donor.
+Catalysis involves the residue at position 1158 playing the role of Nucleophile.
+Catalysis involves the residue at position 1297 playing the role of .
+Catalysis involves the residue at position 1299 playing the role of .
+Catalysis involves the residue at position 388 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 746 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 932 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 816 playing the role of Charge relay system.
+Catalysis involves the residue at position 849 playing the role of Charge relay system.
+Catalysis involves the residue at position 449 playing the role of Nucleophile.
+Catalysis involves the residue at position 728 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 995 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1315 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1492 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1897 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2045 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 267 playing the role of Proton acceptor; specific for (S)-substrate epimerization.
+Catalysis involves the residue at position 987 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1311 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 2058 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 420 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 336 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 259 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 259 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 206 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 988 playing the role of Proton acceptor.
+Catalysis involves the residue at position 385 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 556 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 268 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1039 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 282 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 122 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 36 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 261 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 333 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 31 playing the role of Pros-phosphohistidine intermediate.
+Catalysis involves the residue at position 572 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1035 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2310 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2483 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 623 playing the role of For acyltransferase activity.
+Catalysis involves the residue at position 929 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1095 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 507 playing the role of Nucleophile.
+Catalysis involves the residue at position 569 playing the role of Proton donor.
+Catalysis involves the residue at position 1614 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 230 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 379 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 721 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 248 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 62 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 426 playing the role of Nucleophile.
+Catalysis involves the residue at position 580 playing the role of Proton donor.
+Catalysis involves the residue at position 569 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 72 playing the role of Acid/base catalyst.
+Catalysis involves the residue at position 75 playing the role of Acid/base catalyst.
+Catalysis involves the residue at position 1065 playing the role of Proton donor; for phlorizin hydrolase/Glycosylceramidase activity.
+Catalysis involves the residue at position 1273 playing the role of Nucleophile; for phlorizin hydrolase/Glycosylceramidase activity.
+Catalysis involves the residue at position 1538 playing the role of Proton donor; for lactase activity.
+Catalysis involves the residue at position 1749 playing the role of Nucleophile; for lactase activity.
+Catalysis involves the residue at position 568 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 183 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 498 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 227 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 572 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 81 playing the role of For GATase activity.
+Catalysis involves the residue at position 194 playing the role of For GATase activity.
+Catalysis involves the residue at position 196 playing the role of For GATase activity.
+Catalysis involves the residue at position 108 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 1261 playing the role of Proton acceptor.
+Catalysis involves the residue at position 318 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 234 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 478 playing the role of Charge relay system.
+Catalysis involves the residue at position 418 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 391 playing the role of Proton acceptor 1.
+Catalysis involves the residue at position 520 playing the role of Proton donor 1.
+Catalysis involves the residue at position 989 playing the role of Proton acceptor 2.
+Catalysis involves the residue at position 1118 playing the role of Proton donor 2.
+Catalysis involves the residue at position 740 playing the role of Proton donor.
+Catalysis involves the residue at position 34 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 380 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1082 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1376 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 212 playing the role of Proton donors.
+Catalysis involves the residue at position 290 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 179 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 1308 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 142 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 115 playing the role of Schiff-base intermediate with acetoacetate.
+Catalysis involves the residue at position 419 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 145 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 182 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 114 playing the role of Electrophile.
+Catalysis involves the residue at position 139 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 198 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 308 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 308 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 433 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 454 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 262 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 78 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 359 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 163 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 298 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 339 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 722 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1372 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1570 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2234 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 542 playing the role of Proton donor.
+Catalysis involves the residue at position 1303 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1545 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1586 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 422 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 87 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 406 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 969 playing the role of .
+Catalysis involves the residue at position 973 playing the role of .
+Catalysis involves the residue at position 296 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 1182 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1424 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1465 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 198 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 380 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 659 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 315 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 461 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 630 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1142 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1605 playing the role of .
+Catalysis involves the residue at position 189 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 160 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 186 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 574 playing the role of Charge relay system.
+Catalysis involves the residue at position 694 playing the role of Charge relay system.
+Catalysis involves the residue at position 349 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 103 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 389 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 70 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 111 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 108 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 990 playing the role of Proton acceptor.
+Catalysis involves the residue at position 198 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 358 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 144 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 439 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 441 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 756 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1182 playing the role of Nucleophile.
+Catalysis involves the residue at position 1310 playing the role of .
+Catalysis involves the residue at position 1312 playing the role of .
+Catalysis involves the residue at position 205 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 377 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 649 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 190 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 180 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 895 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 150 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 318 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 131 playing the role of For MoaC activity.
+Catalysis involves the residue at position 1905 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 246 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 1515 playing the role of Proton acceptor.
+Catalysis involves the residue at position 146 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 268 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 576 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 750 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 215 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 392 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 672 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 980 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1138 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 843 playing the role of Charge relay system.
+Catalysis involves the residue at position 985 playing the role of Charge relay system.
+Catalysis involves the residue at position 955 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 268 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 26 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 211 playing the role of Proton donors.
+Catalysis involves the residue at position 34 playing the role of For GATase activity.
+Catalysis involves the residue at position 710 playing the role of Charge relay system.
+Catalysis involves the residue at position 330 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 883 playing the role of Proton acceptor.
+Catalysis involves the residue at position 558 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 630 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 593 playing the role of Proton donor.
+Catalysis involves the residue at position 1156 playing the role of Proton acceptor.
+Catalysis involves the residue at position 231 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 14 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 307 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 832 playing the role of Charge relay system.
+Catalysis involves the residue at position 465 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 843 playing the role of Proton donor.
+Catalysis involves the residue at position 391 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 576 playing the role of .
+Catalysis involves the residue at position 519 playing the role of Proton donor.
+Catalysis involves the residue at position 382 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 689 playing the role of Proton acceptor.
+Catalysis involves the residue at position 147 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 233 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 510 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 947 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 264 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 441 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 716 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1045 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1232 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1685 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 149 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 470 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 1028 playing the role of Proton acceptor.
+Catalysis involves the residue at position 286 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 1842 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 124 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 1350 playing the role of Proton acceptor.
+Catalysis involves the residue at position 597 playing the role of Proton acceptor.
+Catalysis involves the residue at position 496 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 361 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 128 playing the role of Schiff-base intermediate with KHG or pyruvate.
+Catalysis involves the residue at position 1547 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 579 playing the role of Nucleophile.
+Catalysis involves the residue at position 1134 playing the role of Proton acceptor.
+Catalysis involves the residue at position 756 playing the role of Proton donor.
+Catalysis involves the residue at position 714 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1322 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 592 playing the role of .
+Catalysis involves the residue at position 357 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 475 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 760 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 264 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 87 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 192 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 21 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 566 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 449 playing the role of For 3-hydroxyacyl-CoA dehydrogenase activity.
+Catalysis involves the residue at position 171 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 355 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 519 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1239 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 370 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 577 playing the role of Proton acceptor.
+Catalysis involves the residue at position 425 playing the role of Nucleophile; for NAALADase activity.
+Catalysis involves the residue at position 457 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1261 playing the role of Nucleophile.
+Catalysis involves the residue at position 1379 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1051 playing the role of Nucleophile.
+Catalysis involves the residue at position 1109 playing the role of Charge relay system.
+Catalysis involves the residue at position 101 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 158 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 262 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 262 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 1407 playing the role of .
+Catalysis involves the residue at position 1452 playing the role of .
+Catalysis involves the residue at position 468 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 844 playing the role of Proton donor.
+Catalysis involves the residue at position 298 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 133 playing the role of Proton donor/acceptor; for FAICAR cyclization activity.
+Catalysis involves the residue at position 260 playing the role of Proton acceptor; for AICAR formyltransferase activity.
+Catalysis involves the residue at position 656 playing the role of Proton acceptor.
+Catalysis involves the residue at position 391 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 168 playing the role of Proton donors.
+Catalysis involves the residue at position 61 playing the role of Proton donor; for PsiMP glycosidase activity.
+Catalysis involves the residue at position 196 playing the role of Nucleophile; for PsiMP glycosidase activity.
+Catalysis involves the residue at position 247 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 980 playing the role of Proton acceptor.
+Catalysis involves the residue at position 176 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 466 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 684 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 419 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 760 playing the role of .
+Catalysis involves the residue at position 486 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 563 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1000 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 2273 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2432 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 271 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 739 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1348 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1540 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 149 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 24 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 258 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 359 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 794 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 268 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 829 playing the role of Proton acceptor.
+Catalysis involves the residue at position 485 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 670 playing the role of Charge relay system.
+Catalysis involves the residue at position 426 playing the role of Charge relay system.
+Catalysis involves the residue at position 1408 playing the role of Proton acceptor.
+Catalysis involves the residue at position 365 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 559 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 1233 playing the role of Nucleophile.
+Catalysis involves the residue at position 1351 playing the role of Proton acceptor.
+Catalysis involves the residue at position 717 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 986 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 2065 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 1156 playing the role of Nucleophile.
+Catalysis involves the residue at position 1279 playing the role of .
+Catalysis involves the residue at position 1281 playing the role of .
+Catalysis involves the residue at position 23 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 172 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 80 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 313 playing the role of For protease activity.
+Catalysis involves the residue at position 1184 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 211 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 264 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 185 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 1208 playing the role of Proton acceptor.
+Catalysis involves the residue at position 386 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 563 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 180 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 217 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 854 playing the role of Nucleophile.
+Catalysis involves the residue at position 608 playing the role of Proton donor.
+Catalysis involves the residue at position 199 playing the role of Proton donors.
+Catalysis involves the residue at position 54 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 87 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 271 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 186 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 229 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 232 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.
+Catalysis involves the residue at position 554 playing the role of .
+Catalysis involves the residue at position 2617 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 394 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1032 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1223 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 704 playing the role of .
+Catalysis involves the residue at position 611 playing the role of .
+Catalysis involves the residue at position 598 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 465 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 467 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 151 playing the role of Proton donors.
+Catalysis involves the residue at position 76 playing the role of Electrophile.
+Catalysis involves the residue at position 690 playing the role of .
+Catalysis involves the residue at position 733 playing the role of .
+Catalysis involves the residue at position 492 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 1349 playing the role of Nucleophile.
+Catalysis involves the residue at position 1467 playing the role of Proton acceptor.
+Catalysis involves the residue at position 246 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 237 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 526 playing the role of Proton donor.
+Catalysis involves the residue at position 627 playing the role of Nucleophile.
+Catalysis involves the residue at position 61 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 334 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 205 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 263 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 567 playing the role of Proton donor.
+Catalysis involves the residue at position 41 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 139 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 129 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 114 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 119 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 142 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 543 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 217 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 831 playing the role of .
+Catalysis involves the residue at position 882 playing the role of .
+Catalysis involves the residue at position 891 playing the role of .
+Catalysis involves the residue at position 524 playing the role of Nucleophile.
+Catalysis involves the residue at position 329 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 943 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 500 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 441 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 310 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 632 playing the role of Proton acceptor.
+Catalysis involves the residue at position 212 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1165 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 650 playing the role of .
+Catalysis involves the residue at position 1295 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1120 playing the role of For nuclease activity.
+Catalysis involves the residue at position 108 playing the role of For GATase activity.
+Catalysis involves the residue at position 45 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 216 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 974 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 529 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1284 playing the role of .
+Catalysis involves the residue at position 1286 playing the role of .
+Catalysis involves the residue at position 534 playing the role of Proton donor.
+Catalysis involves the residue at position 260 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 164 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 540 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 675 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1317 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1504 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1074 playing the role of Proton acceptor.
+Catalysis involves the residue at position 255 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 83 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 1217 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1458 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1499 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 205 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 191 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 211 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 662 playing the role of For acyltransferase activity.
+Catalysis involves the residue at position 967 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1128 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 655 playing the role of Proton donor.
+Catalysis involves the residue at position 971 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1161 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1106 playing the role of Proton acceptor.
+Catalysis involves the residue at position 843 playing the role of .
+Catalysis involves the residue at position 634 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 955 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 325 playing the role of Proton acceptor; for succinyltransferase activity.
+Catalysis involves the residue at position 774 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1032 playing the role of Proton acceptor.
+Catalysis involves the residue at position 323 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 368 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 389 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 55 playing the role of For acetyl esterase activity.
+Catalysis involves the residue at position 271 playing the role of For acetyl esterase activity.
+Catalysis involves the residue at position 274 playing the role of For acetyl esterase activity.
+Catalysis involves the residue at position 744 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 735 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1021 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1356 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1546 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2009 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 427 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 457 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 879 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 211 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 99 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 144 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 748 playing the role of Nucleophile.
+Catalysis involves the residue at position 534 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 238 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 163 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 646 playing the role of Proton acceptor.
+Catalysis involves the residue at position 127 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 1732 playing the role of .
+Catalysis involves the residue at position 412 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 571 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 811 playing the role of Proton acceptor.
+Catalysis involves the residue at position 629 playing the role of Acyl-ester intermediate; for acyltransferase activity.
+Catalysis involves the residue at position 934 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1100 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 722 playing the role of Proton donor.
+Catalysis involves the residue at position 563 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 698 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1334 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 222 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 326 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 366 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 661 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1188 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 181 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 399 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 524 playing the role of Proton donor.
+Catalysis involves the residue at position 98 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 155 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 297 playing the role of For protease activity.
+Catalysis involves the residue at position 489 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 387 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 223 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 291 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 157 playing the role of Nucleophile and monoketide coumarate intermediate.
+Catalysis involves the residue at position 392 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 240 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 226 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 222 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 413 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 517 playing the role of Nucleophile.
+Catalysis involves the residue at position 69 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 153 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 979 playing the role of .
+Catalysis involves the residue at position 254 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 712 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 386 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 423 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 418 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 140 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 1193 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 771 playing the role of Proton acceptor.
+Catalysis involves the residue at position 500 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 249 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 337 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 441 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 302 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 154 playing the role of Electrophile.
+Catalysis involves the residue at position 222 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 281 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 689 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1016 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1216 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 584 playing the role of Proton acceptor.
+Catalysis involves the residue at position 231 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 985 playing the role of Nucleophile.
+Catalysis involves the residue at position 1105 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1500 playing the role of Proton donor; for sucrase activity.
+Catalysis involves the residue at position 593 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 252 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 1721 playing the role of Proton acceptor.
+Catalysis involves the residue at position 249 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 719 playing the role of Proton donor.
+Catalysis involves the residue at position 407 playing the role of Proton donor.
+Catalysis involves the residue at position 108 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 599 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 99 playing the role of Nucleophile; for thioesterase activity.
+Catalysis involves the residue at position 233 playing the role of Proton acceptor; for thioesterase activity.
+Catalysis involves the residue at position 481 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 676 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 227 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 989 playing the role of For nuclease activity.
+Catalysis involves the residue at position 338 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 201 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 374 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1012 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 513 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 482 playing the role of Nucleophile.
+Catalysis involves the residue at position 552 playing the role of Proton donor.
+Catalysis involves the residue at position 654 playing the role of Proton acceptor.
+Catalysis involves the residue at position 241 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 20 playing the role of For GATase activity.
+Catalysis involves the residue at position 202 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 259 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 151 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 231 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 900 playing the role of Proton acceptor.
+Catalysis involves the residue at position 174 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 630 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 948 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1117 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 434 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 472 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 635 playing the role of Proton donor.
+Catalysis involves the residue at position 1758 playing the role of .
+Catalysis involves the residue at position 13 playing the role of Proton acceptor; for FBP phosphatase activity.
+Catalysis involves the residue at position 517 playing the role of Proton donor.
+Catalysis involves the residue at position 38 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 106 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 825 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 215 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 199 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 338 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 676 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1000 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 324 playing the role of S-methylcysteine intermediate.
+Catalysis involves the residue at position 658 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 155 playing the role of Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity.
+Catalysis involves the residue at position 212 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 1068 playing the role of Proton acceptor.
+Catalysis involves the residue at position 308 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 272 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 40 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 366 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 515 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 515 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 532 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1735 playing the role of .
+Catalysis involves the residue at position 542 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 677 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 716 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 984 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1475 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2216 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2367 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2399 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 966 playing the role of Proton acceptor.
+Catalysis involves the residue at position 564 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 699 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 742 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 560 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 564 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 440 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 136 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 311 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 52 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 281 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 120 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 125 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 148 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 732 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 980 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1293 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1479 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 648 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1125 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 159 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1164 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 283 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 762 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 562 playing the role of Charge relay system.
+Catalysis involves the residue at position 612 playing the role of Charge relay system.
+Catalysis involves the residue at position 525 playing the role of Nucleophile.
+Catalysis involves the residue at position 709 playing the role of Charge relay system.
+Catalysis involves the residue at position 741 playing the role of Charge relay system.
+Catalysis involves the residue at position 427 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 87 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1041 playing the role of .
+Catalysis involves the residue at position 1043 playing the role of .
+Catalysis involves the residue at position 1048 playing the role of .
+Catalysis involves the residue at position 294 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 675 playing the role of Proton donor.
+Catalysis involves the residue at position 435 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 575 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1646 playing the role of .
+Catalysis involves the residue at position 717 playing the role of Charge relay system.
+Catalysis involves the residue at position 851 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 256 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 484 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 580 playing the role of Nucleophile.
+Catalysis involves the residue at position 236 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 286 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 307 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 11 playing the role of For RuvC-like nuclease domain.
+Catalysis involves the residue at position 995 playing the role of Proton acceptor for HNH nuclease domain.
+Catalysis involves the residue at position 552 playing the role of Nucleophile.
+Catalysis involves the residue at position 455 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 356 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 246 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 131 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 652 playing the role of Nucleophile.
+Catalysis involves the residue at position 379 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 242 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 242 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 569 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 396 playing the role of Proton acceptor 1.
+Catalysis involves the residue at position 525 playing the role of Proton donor 1.
+Catalysis involves the residue at position 994 playing the role of Proton acceptor 2.
+Catalysis involves the residue at position 1123 playing the role of Proton donor 2.
+Catalysis involves the residue at position 161 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 259 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 671 playing the role of .
+Catalysis involves the residue at position 301 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 354 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 278 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 442 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 201 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 549 playing the role of .
+Catalysis involves the residue at position 454 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 121 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 30 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 6 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 849 playing the role of Proton acceptor.
+Catalysis involves the residue at position 943 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 116 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 957 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 525 playing the role of For mutarotase activity.
+Catalysis involves the residue at position 878 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 783 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 2023 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 293 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 460 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 665 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 583 playing the role of Charge relay system.
+Catalysis involves the residue at position 86 playing the role of For formimidoyltransferase activity.
+Catalysis involves the residue at position 113 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 452 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 157 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 736 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 13 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 516 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 49 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 30 playing the role of Proton donor.
+Catalysis involves the residue at position 340 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 1034 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1225 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 844 playing the role of Charge relay system.
+Catalysis involves the residue at position 920 playing the role of Charge relay system.
+Catalysis involves the residue at position 1016 playing the role of Proton donor.
+Catalysis involves the residue at position 113 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 198 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 290 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 169 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 79 playing the role of Phosphothreonine intermediate.
+Catalysis involves the residue at position 814 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 869 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 956 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 381 playing the role of Proton donor.
+Catalysis involves the residue at position 1154 playing the role of Proton acceptor.
+Catalysis involves the residue at position 105 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 369 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 241 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 322 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 109 playing the role of Charge relay.
+Catalysis involves the residue at position 272 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 93 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1503 playing the role of .
+Catalysis involves the residue at position 320 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 741 playing the role of Proton acceptor.
+Catalysis involves the residue at position 345 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 260 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 718 playing the role of Charge relay system.
+Catalysis involves the residue at position 324 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 326 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 329 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 218 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 210 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 217 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 565 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 534 playing the role of For mutarotase activity.
+Catalysis involves the residue at position 872 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1540 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 317 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 162 playing the role of Electrophile.
+Catalysis involves the residue at position 255 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 488 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 866 playing the role of Proton acceptor.
+Catalysis involves the residue at position 212 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 547 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 503 playing the role of Charge relay system.
+Catalysis involves the residue at position 597 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 100 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 592 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 273 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 387 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 387 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 664 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 987 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1157 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 900 playing the role of .
+Catalysis involves the residue at position 870 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 240 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 200 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 166 playing the role of Proton acceptor; specific for S-mandelate.
+Catalysis involves the residue at position 297 playing the role of Proton acceptor; specific for R-mandelate.
+Catalysis involves the residue at position 878 playing the role of .
+Catalysis involves the residue at position 529 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 101 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 338 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 433 playing the role of Proton acceptor; for hydroxyethylthiazole kinase activity.
+Catalysis involves the residue at position 347 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 666 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 411 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 660 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 999 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1173 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 199 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 205 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 324 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 267 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 1035 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 448 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 639 playing the role of .
+Catalysis involves the residue at position 398 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 638 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 492 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 145 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 631 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 831 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 104 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 455 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 831 playing the role of Proton donor.
+Catalysis involves the residue at position 187 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 198 playing the role of Proton donor and proton acceptor.
+Catalysis involves the residue at position 432 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 468 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1136 playing the role of Proton acceptor.
+Catalysis involves the residue at position 784 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 618 playing the role of Nucleophile.
+Catalysis involves the residue at position 839 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 25 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 121 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 491 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1176 playing the role of .
+Catalysis involves the residue at position 1276 playing the role of Proton acceptor.
+Catalysis involves the residue at position 299 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 304 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 310 playing the role of Proton donor.
+Catalysis involves the residue at position 1014 playing the role of Nucleophile.
+Catalysis involves the residue at position 411 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 130 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 842 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 70 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 902 playing the role of .
+Catalysis involves the residue at position 211 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 105 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 244 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 284 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 569 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 898 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1074 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 173 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 892 playing the role of Proton donor.
+Catalysis involves the residue at position 313 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 65 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 464 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 184 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 469 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 271 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 64 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 141 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 896 playing the role of Charge relay system.
+Catalysis involves the residue at position 1029 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 99 playing the role of Proton donor/acceptor; for DHNA activity.
+Catalysis involves the residue at position 775 playing the role of Nucleophile.
+Catalysis involves the residue at position 527 playing the role of Nucleophile.
+Catalysis involves the residue at position 610 playing the role of Charge relay system.
+Catalysis involves the residue at position 508 playing the role of Charge relay system.
+Catalysis involves the residue at position 864 playing the role of Proton acceptor.
+Catalysis involves the residue at position 448 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 272 playing the role of N6-(4-deoxychorismate)-lysine intermediate.
+Catalysis involves the residue at position 454 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 118 playing the role of Nucleophile; for deubiquitinase activity.
+Catalysis involves the residue at position 103 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 170 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 161 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 580 playing the role of .
+Catalysis involves the residue at position 293 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 346 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 420 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 247 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 85 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 1114 playing the role of Nucleophile.
+Catalysis involves the residue at position 630 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 2343 playing the role of Proton acceptor.
+Catalysis involves the residue at position 111 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 501 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 160 playing the role of Proton donor; for a subset of substrates.
+Catalysis involves the residue at position 514 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 156 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 346 playing the role of Amidino-cysteine intermediate.
+Catalysis involves the residue at position 89 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 748 playing the role of Proton acceptor.
+Catalysis involves the residue at position 513 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 88 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 686 playing the role of Charge relay system.
+Catalysis involves the residue at position 1006 playing the role of .
+Catalysis involves the residue at position 777 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 312 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 410 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 464 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 164 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 234 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 2587 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1183 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 304 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 994 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 826 playing the role of Proton acceptor.
+Catalysis involves the residue at position 51 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 621 playing the role of .
+Catalysis involves the residue at position 141 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 300 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 357 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 805 playing the role of .
+Catalysis involves the residue at position 187 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 365 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 802 playing the role of .
+Catalysis involves the residue at position 1235 playing the role of Nucleophile.
+Catalysis involves the residue at position 1366 playing the role of .
+Catalysis involves the residue at position 1368 playing the role of .
+Catalysis involves the residue at position 951 playing the role of Proton acceptor.
+Catalysis involves the residue at position 139 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 652 playing the role of .
+Catalysis involves the residue at position 87 playing the role of For GATase activity.
+Catalysis involves the residue at position 419 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 567 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 429 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 323 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 645 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1122 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 381 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 230 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 233 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.
+Catalysis involves the residue at position 776 playing the role of Proton donor.
+Catalysis involves the residue at position 534 playing the role of Nucleophile.
+Catalysis involves the residue at position 627 playing the role of Proton acceptor.
+Catalysis involves the residue at position 152 playing the role of Proton donors.
+Catalysis involves the residue at position 469 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 385 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 406 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 289 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 154 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 245 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 394 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 213 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 208 playing the role of Proton donors.
+Catalysis involves the residue at position 323 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 49 playing the role of Proton acceptor; for enolization step.
+Catalysis involves the residue at position 115 playing the role of For ring-opening step.
+Catalysis involves the residue at position 117 playing the role of Proton acceptor; for ring-opening step.
+Catalysis involves the residue at position 122 playing the role of For ring-opening step.
+Catalysis involves the residue at position 1944 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 651 playing the role of .
+Catalysis involves the residue at position 710 playing the role of .
+Catalysis involves the residue at position 85 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 414 playing the role of For NAALADase activity.
+Catalysis involves the residue at position 303 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 704 playing the role of Proton donor.
+Catalysis involves the residue at position 158 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 592 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 942 playing the role of .
+Catalysis involves the residue at position 1994 playing the role of Proton acceptor.
+Catalysis involves the residue at position 440 playing the role of Proton acceptor; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 442 playing the role of Nucleophile; for GTP cyclohydrolase activity.
+Catalysis involves the residue at position 105 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 185 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 621 playing the role of Charge relay system.
+Catalysis involves the residue at position 664 playing the role of Charge relay system.
+Catalysis involves the residue at position 309 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 537 playing the role of For mutarotase activity.
+Catalysis involves the residue at position 298 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 283 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1020 playing the role of Proton donor.
+Catalysis involves the residue at position 784 playing the role of Proton acceptor.
+Catalysis involves the residue at position 472 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 144 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 262 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 146 playing the role of Proton donors.
+Catalysis involves the residue at position 939 playing the role of .
+Catalysis involves the residue at position 992 playing the role of Nucleophile.
+Catalysis involves the residue at position 853 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 416 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 495 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 43 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 100 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 246 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 35 playing the role of Charge relay system.
+Catalysis involves the residue at position 267 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 154 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 930 playing the role of Proton acceptor.
+Catalysis involves the residue at position 429 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 450 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 168 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 100 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 684 playing the role of Charge relay system.
+Catalysis involves the residue at position 907 playing the role of .
+Catalysis involves the residue at position 188 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 327 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1201 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2336 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 10 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 422 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 179 playing the role of Charge relay system; for urate oxidase activity.
+Catalysis involves the residue at position 239 playing the role of Charge relay system; for urate oxidase activity.
+Catalysis involves the residue at position 253 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 174 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 451 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 525 playing the role of For molybdenum cofactor biosynthesis protein C activity.
+Catalysis involves the residue at position 1169 playing the role of Proton acceptor.
+Catalysis involves the residue at position 426 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 716 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 633 playing the role of .
+Catalysis involves the residue at position 837 playing the role of .
+Catalysis involves the residue at position 24 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 309 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 251 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 854 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1199 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1228 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 200 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 375 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 992 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1179 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 312 playing the role of For OMPdecase activity.
+Catalysis involves the residue at position 1109 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 630 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 460 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 229 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 368 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 188 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 466 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 192 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 158 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 334 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 396 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 697 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 1218 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 670 playing the role of Proton acceptor.
+Catalysis involves the residue at position 672 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 73 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 288 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 107 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 798 playing the role of Charge relay system.
+Catalysis involves the residue at position 961 playing the role of Charge relay system.
+Catalysis involves the residue at position 652 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 34 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 928 playing the role of Proton acceptor.
+Catalysis involves the residue at position 2321 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2513 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 219 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 482 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 653 playing the role of Nucleophile.
+Catalysis involves the residue at position 442 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 516 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 670 playing the role of For acyltransferase activity.
+Catalysis involves the residue at position 340 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 361 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 67 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 175 playing the role of Pros-phosphohistidine intermediate; for HPr activity.
+Catalysis involves the residue at position 460 playing the role of Tele-phosphohistidine intermediate; for PTS EI activity.
+Catalysis involves the residue at position 768 playing the role of Proton donor.
+Catalysis involves the residue at position 391 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 256 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 271 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1175 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1203 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 278 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 108 playing the role of Non-phosphorylated intermediate.
+Catalysis involves the residue at position 6 playing the role of Proton acceptor.
+Catalysis involves the residue at position 590 playing the role of Proton donor.
+Catalysis involves the residue at position 721 playing the role of Proton acceptor.
+Catalysis involves the residue at position 108 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 493 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 174 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 568 playing the role of Nucleophile.
+Catalysis involves the residue at position 566 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 657 playing the role of For protease activity.
+Catalysis involves the residue at position 707 playing the role of Nucleophile; for protease activity.
+Catalysis involves the residue at position 105 playing the role of Cysteine sulfenic acid (-SOH) intermediate.
+Catalysis involves the residue at position 395 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 467 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 276 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 646 playing the role of Proton donor.
+Catalysis involves the residue at position 569 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 2064 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 247 playing the role of Tele-hemiaminal-histidine intermediate.
+Catalysis involves the residue at position 266 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1546 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 284 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 1271 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 600 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 91 playing the role of For GATase activity.
+Catalysis involves the residue at position 678 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 962 playing the role of Proton acceptor.
+Catalysis involves the residue at position 341 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 581 playing the role of Proton acceptor.
+Catalysis involves the residue at position 177 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 454 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 491 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 737 playing the role of Proton acceptor.
+Catalysis involves the residue at position 392 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 460 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 836 playing the role of Proton donor.
+Catalysis involves the residue at position 1568 playing the role of Nucleophile.
+Catalysis involves the residue at position 1881 playing the role of Proton acceptor.
+Catalysis involves the residue at position 224 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 492 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 22 playing the role of For GATase activity.
+Catalysis involves the residue at position 78 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 165 playing the role of For GATase activity.
+Catalysis involves the residue at position 167 playing the role of For GATase activity.
+Catalysis involves the residue at position 1127 playing the role of .
+Catalysis involves the residue at position 518 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 839 playing the role of .
+Catalysis involves the residue at position 204 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1550 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1841 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 82 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 409 playing the role of Proton acceptor; via carboxylate.
+Catalysis involves the residue at position 137 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 246 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 697 playing the role of Proton acceptor.
+Catalysis involves the residue at position 572 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 82 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 1016 playing the role of .
+Catalysis involves the residue at position 1015 playing the role of .
+Catalysis involves the residue at position 1058 playing the role of .
+Catalysis involves the residue at position 55 playing the role of Cysteine sulfenic acid (-SOH) intermediate (for peroxiredoxin activity).
+Catalysis involves the residue at position 291 playing the role of Nucleophile.
+Catalysis involves the residue at position 908 playing the role of Charge relay system.
+Catalysis involves the residue at position 957 playing the role of Charge relay system.
+Catalysis involves the residue at position 1050 playing the role of Charge relay system.
+Catalysis involves the residue at position 296 playing the role of Proton donor; for delta-elimination activity.
+Catalysis involves the residue at position 912 playing the role of Proton donor.
+Catalysis involves the residue at position 265 playing the role of Acyl-anhydride intermediate.
+Catalysis involves the residue at position 804 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 841 playing the role of .
+Catalysis involves the residue at position 472 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 399 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 84 playing the role of Nucleophile, for hydrolase activity.
+Catalysis involves the residue at position 85 playing the role of Nucleophile, for hydrolase activity.
+Catalysis involves the residue at position 149 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 469 playing the role of Nucleophile.
+Catalysis involves the residue at position 151 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 12 playing the role of Nucleophile; for lipase activity.
+Catalysis involves the residue at position 872 playing the role of .
+Catalysis involves the residue at position 664 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 12 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 392 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 201 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 276 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 1452 playing the role of For DNA cleavage activity.
+Catalysis involves the residue at position 67 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 29 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 221 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 78 playing the role of Phosphothreonine intermediate.
+Catalysis involves the residue at position 700 playing the role of Proton acceptor.
+Catalysis involves the residue at position 161 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1035 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1369 playing the role of Proton acceptor.
+Catalysis involves the residue at position 305 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 178 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 684 playing the role of Proton donor.
+Catalysis involves the residue at position 562 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 1169 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1197 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 642 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 524 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 659 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 972 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1290 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 2227 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2385 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2417 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 855 playing the role of Proton donor.
+Catalysis involves the residue at position 797 playing the role of Charge relay system.
+Catalysis involves the residue at position 960 playing the role of Charge relay system.
+Catalysis involves the residue at position 116 playing the role of Charge relay.
+Catalysis involves the residue at position 425 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 481 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 569 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 569 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 800 playing the role of Charge relay system.
+Catalysis involves the residue at position 1109 playing the role of Nucleophile.
+Catalysis involves the residue at position 162 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 827 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 343 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 541 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 773 playing the role of Charge relay system.
+Catalysis involves the residue at position 850 playing the role of Charge relay system.
+Catalysis involves the residue at position 883 playing the role of Charge relay system.
+Catalysis involves the residue at position 648 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 838 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 677 playing the role of Proton donor.
+Catalysis involves the residue at position 466 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1082 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1034 playing the role of Proton acceptor.
+Catalysis involves the residue at position 169 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 293 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 502 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 245 playing the role of Nucleophile or transition state stabilizer.
+Catalysis involves the residue at position 817 playing the role of Charge relay system.
+Catalysis involves the residue at position 163 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 98 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 215 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 2243 playing the role of Proton acceptor.
+Catalysis involves the residue at position 295 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1110 playing the role of .
+Catalysis involves the residue at position 1153 playing the role of .
+Catalysis involves the residue at position 380 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 19 playing the role of Schiff-base intermediate with D-ribose 5-phosphate.
+Catalysis involves the residue at position 1772 playing the role of .
+Catalysis involves the residue at position 1930 playing the role of .
+Catalysis involves the residue at position 1950 playing the role of .
+Catalysis involves the residue at position 1285 playing the role of Proton acceptor.
+Catalysis involves the residue at position 139 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 354 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 1769 playing the role of .
+Catalysis involves the residue at position 1927 playing the role of .
+Catalysis involves the residue at position 1947 playing the role of .
+Catalysis involves the residue at position 143 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 615 playing the role of Charge relay system.
+Catalysis involves the residue at position 763 playing the role of Charge relay system.
+Catalysis involves the residue at position 529 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 122 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 127 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 150 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 1151 playing the role of Proton acceptor.
+Catalysis involves the residue at position 121 playing the role of Schiff-base intermediate with acetoacetate.
+Catalysis involves the residue at position 149 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 438 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 441 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 597 playing the role of For target ssRNA cleavage.
+Catalysis involves the residue at position 602 playing the role of For target ssRNA cleavage.
+Catalysis involves the residue at position 1278 playing the role of For target ssRNA cleavage.
+Catalysis involves the residue at position 1283 playing the role of For target ssRNA cleavage.
+Catalysis involves the residue at position 1650 playing the role of Proton acceptor.
+Catalysis involves the residue at position 432 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 965 playing the role of .
+Catalysis involves the residue at position 1008 playing the role of .
+Catalysis involves the residue at position 777 playing the role of Charge relay system.
+Catalysis involves the residue at position 869 playing the role of Proton donor.
+Catalysis involves the residue at position 723 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 249 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 177 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 214 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 294 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 315 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 384 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 554 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 768 playing the role of For sulfotransferase activity.
+Catalysis involves the residue at position 142 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 376 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 580 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 759 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1367 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1554 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 274 playing the role of N6-(4-deoxychorismate)-lysine intermediate.
+Catalysis involves the residue at position 359 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1180 playing the role of .
+Catalysis involves the residue at position 538 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 916 playing the role of Proton donor.
+Catalysis involves the residue at position 213 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 1253 playing the role of Nucleophile.
+Catalysis involves the residue at position 1371 playing the role of Proton acceptor.
+Catalysis involves the residue at position 121 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 510 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 803 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 58 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 1270 playing the role of Nucleophile.
+Catalysis involves the residue at position 155 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1244 playing the role of Proton acceptor.
+Catalysis involves the residue at position 606 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 445 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 973 playing the role of Proton acceptor.
+Catalysis involves the residue at position 386 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1020 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1509 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2274 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2433 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 109 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 115 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 3 playing the role of Schiff-base intermediate with dihydroxyacetone-P.
+Catalysis involves the residue at position 259 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 280 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 522 playing the role of Charge relay system.
+Catalysis involves the residue at position 322 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1160 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 413 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 158 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 953 playing the role of .
+Catalysis involves the residue at position 116 playing the role of For NAALADase activity.
+Catalysis involves the residue at position 121 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 475 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1116 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1306 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 44 playing the role of Redox-active.
+Catalysis involves the residue at position 442 playing the role of Proton acceptor; for kinase activity.
+Catalysis involves the residue at position 410 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 286 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 77 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 222 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 381 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 789 playing the role of Charge relay system.
+Catalysis involves the residue at position 274 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 105 playing the role of Proton donor; for formyltransferase activity.
+Catalysis involves the residue at position 433 playing the role of Proton acceptor; for decarboxylase activity.
+Catalysis involves the residue at position 618 playing the role of Proton donor; for decarboxylase activity.
+Catalysis involves the residue at position 151 playing the role of For hydroxyacyl-coenzyme A dehydrogenase activity.
+Catalysis involves the residue at position 636 playing the role of .
+Catalysis involves the residue at position 423 playing the role of S-acetylcysteine intermediate.
+Catalysis involves the residue at position 424 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 42 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 262 playing the role of Proton acceptor; specific for L-alanine.
+Catalysis involves the residue at position 267 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 457 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 492 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 63 playing the role of For protease activity.
+Catalysis involves the residue at position 856 playing the role of Proton acceptor.
+Catalysis involves the residue at position 590 playing the role of Proton acceptor.
+Catalysis involves the residue at position 115 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 671 playing the role of Proton donor.
+Catalysis involves the residue at position 329 playing the role of Thioimidate intermediate.
+Catalysis involves the residue at position 533 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 1539 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1830 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 126 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 215 playing the role of For GATase activity.
+Catalysis involves the residue at position 217 playing the role of For GATase activity.
+Catalysis involves the residue at position 1119 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 174 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 359 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 861 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 639 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1149 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 197 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 250 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 786 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 536 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 102 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 626 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 241 playing the role of Schiff-base intermediate with DNA.
+Catalysis involves the residue at position 120 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 843 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 852 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 869 playing the role of For pre-crRNA processing.
+Catalysis involves the residue at position 917 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 1006 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 1255 playing the role of For DNase activity of RuvC domain.
+Catalysis involves the residue at position 1164 playing the role of Nucleophile.
+Catalysis involves the residue at position 1282 playing the role of Proton acceptor.
+Catalysis involves the residue at position 643 playing the role of .
+Catalysis involves the residue at position 1097 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1125 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 353 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1530 playing the role of .
+Catalysis involves the residue at position 587 playing the role of Proton donor.
+Catalysis involves the residue at position 50 playing the role of Proton acceptor; specific for D-alanine.
+Catalysis involves the residue at position 422 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 196 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 186 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 773 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 790 playing the role of Charge relay system.
+Catalysis involves the residue at position 928 playing the role of .
+Catalysis involves the residue at position 1003 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 142 playing the role of Nucleophile; for transacylase activity.
+Catalysis involves the residue at position 261 playing the role of Proton donor/acceptor; for transacylase activity.
+Catalysis involves the residue at position 1501 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 443 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 822 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 1137 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 396 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 75 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 1275 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1518 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1559 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1018 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 82 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 867 playing the role of Proton acceptor.
+Catalysis involves the residue at position 81 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 268 playing the role of For acetyltransferase activity.
+Catalysis involves the residue at position 1788 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 682 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 580 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 1034 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 2309 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2482 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 558 playing the role of Proton donor.
+Catalysis involves the residue at position 262 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 70 playing the role of N6-GMP-lysine intermediate.
+Catalysis involves the residue at position 685 playing the role of Proton donor.
+Catalysis involves the residue at position 198 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 236 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 206 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 316 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 316 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 728 playing the role of Proton acceptor.
+Catalysis involves the residue at position 670 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 244 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1131 playing the role of Proton acceptor.
+Catalysis involves the residue at position 421 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 751 playing the role of Proton donor.
+Catalysis involves the residue at position 64 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 156 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 347 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 540 playing the role of Nucleophile.
+Catalysis involves the residue at position 617 playing the role of Proton donor.
+Catalysis involves the residue at position 415 playing the role of For protease activity; shared with dimeric partner.
+Catalysis involves the residue at position 444 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 529 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 981 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 80 playing the role of For GATase activity.
+Catalysis involves the residue at position 470 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 425 playing the role of Covalent intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 396 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 115 playing the role of Proton donor; for transglycosylase activity.
+Catalysis involves the residue at position 390 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 1964 playing the role of .
+Catalysis involves the residue at position 575 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 754 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1026 playing the role of Proton acceptor.
+Catalysis involves the residue at position 956 playing the role of Proton acceptor.
+Catalysis involves the residue at position 436 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 110 playing the role of Charge relay.
+Catalysis involves the residue at position 667 playing the role of Proton donor.
+Catalysis involves the residue at position 1020 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 397 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 113 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 48 playing the role of Redox-active.
+Catalysis involves the residue at position 975 playing the role of Nucleophile.
+Catalysis involves the residue at position 1095 playing the role of Proton acceptor.
+Catalysis involves the residue at position 232 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 302 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 2025 playing the role of .
+Catalysis involves the residue at position 317 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 81 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 86 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 201 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 284 playing the role of Tryptophan radical intermediate.
+Catalysis involves the residue at position 312 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 652 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 788 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 809 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 55 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 261 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 233 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 272 playing the role of Glycyl thioester intermediate; for adenylyltransferase activity.
+Catalysis involves the residue at position 440 playing the role of Cysteine persulfide intermediate; for sulfurtransferase activity.
+Catalysis involves the residue at position 725 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 537 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 589 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 768 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1376 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1565 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 413 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 35 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 77 playing the role of Proton acceptor in CI (KaiC 1).
+Catalysis involves the residue at position 832 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 274 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 385 playing the role of Charge relay system; for autoendoproteolytic cleavage activity.
+Catalysis involves the residue at position 385 playing the role of Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity.
+Catalysis involves the residue at position 335 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 356 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 515 playing the role of Charge relay system.
+Catalysis involves the residue at position 613 playing the role of Proton donor.
+Catalysis involves the residue at position 565 playing the role of Charge relay system.
+Catalysis involves the residue at position 719 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 800 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 830 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 418 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 407 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 460 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 734 playing the role of Proton acceptor.
+Catalysis involves the residue at position 654 playing the role of For protease activity.
+Catalysis involves the residue at position 699 playing the role of Nucleophile; for protease activity.
+Catalysis involves the residue at position 464 playing the role of Cysteine radical intermediate.
+Catalysis involves the residue at position 578 playing the role of Proton donor.
+Catalysis involves the residue at position 579 playing the role of Charge relay system.
+Catalysis involves the residue at position 545 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 304 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 300 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 353 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 629 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 1318 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 831 playing the role of Proton acceptor.
+Catalysis involves the residue at position 76 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 389 playing the role of Proton acceptor 1.
+Catalysis involves the residue at position 518 playing the role of Proton donor 1.
+Catalysis involves the residue at position 987 playing the role of Proton acceptor 2.
+Catalysis involves the residue at position 1116 playing the role of Proton donor 2.
+Catalysis involves the residue at position 1029 playing the role of Nucleophile.
+Catalysis involves the residue at position 172 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 210 playing the role of Acyl-thioester intermediate.
+Catalysis involves the residue at position 445 playing the role of Phosphohistidine intermediate.
+Catalysis involves the residue at position 710 playing the role of Proton donor.
+Catalysis involves the residue at position 792 playing the role of Proton acceptor.
+Catalysis involves the residue at position 147 playing the role of Schiff-base intermediate with acetaldehyde.
+Catalysis involves the residue at position 20 playing the role of Transition state stabilizer.
+Catalysis involves the residue at position 235 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 711 playing the role of Proton donor.
+Catalysis involves the residue at position 18 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 626 playing the role of .
+Catalysis involves the residue at position 498 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 140 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 269 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 353 playing the role of For GATase activity.
+Catalysis involves the residue at position 355 playing the role of For GATase activity.
+Catalysis involves the residue at position 470 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 237 playing the role of Tele-GMP-histidine intermediate.
+Catalysis involves the residue at position 1160 playing the role of Nucleophile.
+Catalysis involves the residue at position 871 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 78 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 719 playing the role of Charge relay system.
+Catalysis involves the residue at position 795 playing the role of Charge relay system.
+Catalysis involves the residue at position 298 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 25 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1183 playing the role of .
+Catalysis involves the residue at position 227 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 616 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 1044 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 1108 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 182 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 547 playing the role of Proton acceptor.
+Catalysis involves the residue at position 508 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 183 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 297 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 312 playing the role of Proton acceptor; for 3-dehydroquinate synthase activity.
+Catalysis involves the residue at position 877 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1292 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1320 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 714 playing the role of Proton acceptor.
+Catalysis involves the residue at position 520 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 541 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 47 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 126 playing the role of Charge relay.
+Catalysis involves the residue at position 273 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 796 playing the role of Proton acceptor.
+Catalysis involves the residue at position 219 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 335 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 16 playing the role of Charge relay system.
+Catalysis involves the residue at position 269 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 937 playing the role of Proton acceptor.
+Catalysis involves the residue at position 106 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 465 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 3 playing the role of Proton acceptor.
+Catalysis involves the residue at position 103 playing the role of Charge relay.
+Catalysis involves the residue at position 931 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 220 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 563 playing the role of Proton donor.
+Catalysis involves the residue at position 174 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1231 playing the role of .
+Catalysis involves the residue at position 649 playing the role of Charge relay system.
+Catalysis involves the residue at position 661 playing the role of For malonyltransferase activity.
+Catalysis involves the residue at position 965 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 310 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 486 playing the role of Nucleophile.
+Catalysis involves the residue at position 541 playing the role of Proton donor.
+Catalysis involves the residue at position 132 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 188 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 298 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 911 playing the role of Proton donor.
+Catalysis involves the residue at position 843 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 656 playing the role of .
+Catalysis involves the residue at position 18 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 936 playing the role of Proton acceptor.
+Catalysis involves the residue at position 1255 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 607 playing the role of Nucleophile; for GATase activity.
+Catalysis involves the residue at position 697 playing the role of For GATase activity.
+Catalysis involves the residue at position 417 playing the role of Proton donor; shared with dimeric partner.
+Catalysis involves the residue at position 298 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 351 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 911 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 286 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 339 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 371 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 201 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 822 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 1286 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 119 playing the role of Tele-AMP-histidine intermediate.
+Catalysis involves the residue at position 165 playing the role of Involved in ionization of N3 of dUMP, leading to its activation.
+Catalysis involves the residue at position 19 playing the role of Charge relay system.
+Catalysis involves the residue at position 926 playing the role of Proton acceptor.
+Catalysis involves the residue at position 599 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 199 playing the role of Lowers pKa of active site Tyr.
+Catalysis involves the residue at position 1226 playing the role of .
+Catalysis involves the residue at position 1039 playing the role of Proton acceptor.
+Catalysis involves the residue at position 592 playing the role of Charge relay system.
+Catalysis involves the residue at position 687 playing the role of Charge relay system.
+Catalysis involves the residue at position 1193 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 499 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 566 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 412 playing the role of Schiff-base intermediate with substrate; via topaquinone.
+Catalysis involves the residue at position 85 playing the role of Schiff-base intermediate with substrate; via pyruvic acid.
+Catalysis involves the residue at position 99 playing the role of Proton donor; for catalytic activity.
+Catalysis involves the residue at position 275 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 288 playing the role of Proton acceptor; for processing activity.
+Catalysis involves the residue at position 406 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 993 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 2579 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 18 playing the role of Nucleophile; for lipase activity.
+Catalysis involves the residue at position 280 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 1532 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 303 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 683 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 847 playing the role of Tele-phosphohistidine intermediate; for EIIA activity.
+Catalysis involves the residue at position 853 playing the role of Proton acceptor.
+Catalysis involves the residue at position 24 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 537 playing the role of Proton donor.
+Catalysis involves the residue at position 13 playing the role of O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 453 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 547 playing the role of Proton donor.
+Catalysis involves the residue at position 32 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 377 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 209 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 466 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 843 playing the role of Nucleophile.
+Catalysis involves the residue at position 239 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 844 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 1277 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1458 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1969 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2127 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 864 playing the role of For EPSP synthase activity.
+Catalysis involves the residue at position 1212 playing the role of Proton acceptor; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 1240 playing the role of Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity.
+Catalysis involves the residue at position 291 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 434 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 443 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 531 playing the role of Nucleophile.
+Catalysis involves the residue at position 275 playing the role of N6-AMP-lysine intermediate.
+Catalysis involves the residue at position 388 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 90 playing the role of Nucleophile; methyl group acceptor.
+Catalysis involves the residue at position 200 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 1465 playing the role of .
+Catalysis involves the residue at position 1467 playing the role of .
+Catalysis involves the residue at position 1472 playing the role of .
+Catalysis involves the residue at position 172 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 287 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 663 playing the role of Proton donor.
+Catalysis involves the residue at position 695 playing the role of Proton acceptor.
+Catalysis involves the residue at position 118 playing the role of Schiff-base intermediate with DXP.
+Catalysis involves the residue at position 128 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 25 playing the role of O-(5'-phospho-DNA)-serine intermediate.
+Catalysis involves the residue at position 423 playing the role of Nucleophile; for glutamine hydrolysis.
+Catalysis involves the residue at position 203 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 169 playing the role of For GATase activity.
+Catalysis involves the residue at position 171 playing the role of For GATase activity.
+Catalysis involves the residue at position 1993 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 388 playing the role of Proton donor; for pectinesterase activity.
+Catalysis involves the residue at position 409 playing the role of Nucleophile; for pectinesterase activity.
+Catalysis involves the residue at position 730 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 2039 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 25 playing the role of O-(5'-phospho-DNA)-tyrosine intermediate; for relaxase activity.
+Catalysis involves the residue at position 137 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 168 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 524 playing the role of Proton donor 1.
+Catalysis involves the residue at position 993 playing the role of Proton acceptor 2.
+Catalysis involves the residue at position 1122 playing the role of Proton donor 2.
+Catalysis involves the residue at position 212 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 1096 playing the role of .
+Catalysis involves the residue at position 1098 playing the role of .
+Catalysis involves the residue at position 1103 playing the role of .
+Catalysis involves the residue at position 568 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1017 playing the role of For acyl/malonyl transferase activity.
+Catalysis involves the residue at position 2267 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 2421 playing the role of For thioesterase activity.
+Catalysis involves the residue at position 594 playing the role of For Fru-6P isomerization activity.
+Catalysis involves the residue at position 1279 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1519 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 1560 playing the role of For beta-ketoacyl synthase activity.
+Catalysis involves the residue at position 263 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 241 playing the role of Nucleophile; cysteine thiosulfonate intermediate.
+Catalysis involves the residue at position 1287 playing the role of Proton acceptor; for azaheterocycle hydroxylase activity.
+Catalysis involves the residue at position 788 playing the role of Glycyl thioester intermediate.
+Catalysis involves the residue at position 500 playing the role of Nucleophile.
+Catalysis involves the residue at position 434 playing the role of GMP-histidine intermediate.
+Catalysis involves the residue at position 222 playing the role of Proton donor and proton acceptor.
+Catalysis involves the residue at position 1041 playing the role of Proton acceptor; for dehydratase activity.
+Catalysis involves the residue at position 1217 playing the role of Proton donor; for dehydratase activity.
+Catalysis involves the residue at position 1962 playing the role of For Claisen cyclase activity.
+Catalysis involves the residue at position 1005 playing the role of Proton acceptor.
+Catalysis involves the residue at position 975 playing the role of For nuclease activity.
+Catalysis involves the residue at position 574 playing the role of Proton donor.
+Catalysis involves the residue at position 1463 playing the role of Proton acceptor.
+Catalysis involves the residue at position 49 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 1765 playing the role of Proton acceptor.
+Catalysis involves the residue at position 910 playing the role of Charge relay system.
+Catalysis involves the residue at position 959 playing the role of Charge relay system.
+Catalysis involves the residue at position 1052 playing the role of Charge relay system.
+Catalysis involves the residue at position 464 playing the role of 4-aspartylphosphate intermediate.
+Catalysis involves the residue at position 182 playing the role of Tele-UMP-histidine intermediate.
+Catalysis involves the residue at position 1297 playing the role of Proton acceptor.
+Catalysis involves the residue at position 75 playing the role of Phosphocysteine intermediate; for EIIB activity.
+Catalysis involves the residue at position 1474 playing the role of Proton acceptor.
+Catalysis involves the residue at position 11 playing the role of Nucleophile; O-isoaspartyl threonine intermediate.
+Catalysis involves the residue at position 987 playing the role of Nucleophile.
+Catalysis involves the residue at position 1107 playing the role of Proton acceptor.
+Catalysis involves the residue at position 58 playing the role of Thioimide intermediate.
+Catalysis involves the residue at position 640 playing the role of .
+Catalysis involves the residue at position 208 playing the role of Nucleophile; for N-glycosylase activity.
+Catalysis involves the residue at position 487 playing the role of Charge relay system.
+Catalysis involves the residue at position 761 playing the role of O-(3'-phospho-DNA)-tyrosine intermediate.
+Catalysis involves the residue at position 224 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 227 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.
+Catalysis involves the residue at position 371 playing the role of Acyl-ester intermediate; for transpeptidase activity.
+Catalysis involves the residue at position 74 playing the role of Acyl-ester intermediate.
+Catalysis involves the residue at position 785 playing the role of Nucleophile.
+Catalysis involves the residue at position 814 playing the role of Proton donor.
+Catalysis involves the residue at position 172 playing the role of Tele-phosphohistidine intermediate.
+Catalysis involves the residue at position 246 playing the role of Proton donor/acceptor; for phosphatase activity.
+Catalysis involves the residue at position 256 playing the role of AMP-threonine intermediate.
+Catalysis involves the residue at position 576 playing the role of S-palmitoyl cysteine intermediate.
+Catalysis involves the residue at position 99 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 252 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 905 playing the role of Proton acceptor.
+Catalysis involves the residue at position 17 playing the role of Proton acceptor; for FBP phosphatase activity.
+Catalysis involves the residue at position 233 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 236 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.
+Catalysis involves the residue at position 236 playing the role of For autocatalytic cleavage activity.
+Catalysis involves the residue at position 77 playing the role of Cysteine persulfide intermediate.
+Catalysis involves the residue at position 468 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 176 playing the role of Schiff-base intermediate with substrate.
+Catalysis involves the residue at position 400 playing the role of Proton donor/acceptor.
+Catalysis involves the residue at position 81 playing the role of Nucleophile, for hydrolase activity.
+Catalysis involves the residue at position 82 playing the role of Nucleophile, for hydrolase activity.
+Catalysis involves the residue at position 380 playing the role of S-selanylcysteine intermediate.
+Catalysis involves the residue at position 89 playing the role of Phosphoserine intermediate.
+Catalysis involves the residue at position 244 playing the role of Phosphocysteine intermediate.
+Catalysis involves the residue at position 299 playing the role of 5-glutamyl coenzyme A thioester intermediate.
+Catalysis involves the residue at position 1180 playing the role of Nucleophile.
+Catalysis involves the residue at position 227 playing the role of Proton donor/acceptor; for FBP aldolase activity.
+Catalysis involves the residue at position 230 playing the role of Schiff-base intermediate with DHAP; for FBP aldolase activity.