Create multi-model-plant-genome-corpus.py

multi-model-plant-genome-corpus.py

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+from typing import List
+import datasets
+from Bio import SeqIO
+import os
+
+_CITATION = ""
+_DESCRIPTION = """
+
+Dataset made of model plants genomes available on NCBI.
+Default configuration "6kbp" yields chunks of 6.2kbp (100bp overlap on each side). The chunks of DNA are cleaned and processed so that
+they can only contain the letters A, T, C, G and N.
+"""
+_HOMEPAGE = "https://www.ncbi.nlm.nih.gov/"
+_LICENSE = "https://www.ncbi.nlm.nih.gov/home/about/policies/"
+_CHUNK_LENGTHS = [6000,]
+
+def filter_fn(char: str) -> str:
+    """
+    Transforms any letter different from a base nucleotide into an 'N'.
+    """
+    if char in {'A', 'T', 'C', 'G'}:
+    return char
+    else:
+    return 'N'
+    
+def clean_sequence(seq: str) -> str:
+    """
+    Process a chunk of DNA to have all letters in upper and restricted to
+    A, T, C, G and N.
+    """
+    seq = seq.upper()
+    seq = map(filter_fn, seq)
+    seq = ''.join(list(seq))
+    return seq
+    
+class PlantMultiSpeciesGenomesConfig(datasets.BuilderConfig):
+    """BuilderConfig for the Plant Multi Species Pre-training Dataset."""
+    Copy codedef __init__(self, *args, chunk_length: int, overlap: int = 100, **kwargs):
+        """BuilderConfig for the multi species genomes.
+        Args:
+            chunk_length (:obj:`int`): Chunk length.
+            overlap: (:obj:`int`): Overlap in base pairs for two consecutive chunks (defaults to 100).
+            **kwargs: keyword arguments forwarded to super.
+        """
+        num_kbp = int(chunk_length/1000)
+        super().__init__(
+            *args,
+            name=f'{num_kbp}kbp',
+            **kwargs,
+        )
+        self.chunk_length = chunk_length
+        self.overlap = overlap
+
+class PlantMultiSpeciesGenomes(datasets.GeneratorBasedBuilder):
+    """Genomes from multiple plant species, filtered and split into chunks of consecutive
+    nucleotides."""
+    Copy codeVERSION = datasets.Version("1.1.0")
+    BUILDER_CONFIG_CLASS = PlantMultiSpeciesGenomesConfig
+    BUILDER_CONFIGS = [PlantMultiSpeciesGenomesConfig(chunk_length=chunk_length) for chunk_length in _CHUNK_LENGTHS]
+    DEFAULT_CONFIG_NAME = "6kbp"
+    
+    def _info(self):
+    
+        features = datasets.Features(
+            {
+                "sequence": datasets.Value("string"),
+                "description": datasets.Value("string"),
+                "start_pos": datasets.Value("int32"),
+                "end_pos": datasets.Value("int32"),
+            }
+        )
+        return datasets.DatasetInfo(
+            description=_DESCRIPTION,
+            features=features,
+            homepage=_HOMEPAGE,
+            license=_LICENSE,
+            citation=_CITATION,
+        )
+    
+    def _split_generators(self, dl_manager: datasets.DownloadManager) -> List[datasets.SplitGenerator]:
+        # Get the list of genome files in the plant_genomes directory
+        genome_dir = "plant_genomes"
+        genome_files = [os.path.join(genome_dir, f) for f in os.listdir(genome_dir) if f.endswith(".fna.gz")]
+        
+        return [
+            datasets.SplitGenerator(name=datasets.Split.TRAIN, gen_kwargs={"files": genome_files, "chunk_length": self.config.chunk_length})
+        ]
+    
+    # method parameters are unpacked from `gen_kwargs` as given in `_split_generators`
+    def _generate_examples(self, files, chunk_length):
+        key = 0
+        for file in files:
+            with open(file, 'rt') as f:
+                fasta_sequences = SeqIO.parse(f, 'fasta')
+    
+                for record in fasta_sequences:
+                    sequence, description = str(record.seq), record.description
+    
+                    # clean chromosome sequence
+                    sequence = clean_sequence(sequence)
+                    seq_length = len(sequence)
+    
+                    # split into chunks
+                    num_chunks = (seq_length - 2 * self.config.overlap) // chunk_length
+    
+                    if num_chunks < 1:
+                        continue
+    
+                    sequence = sequence[:(chunk_length * num_chunks + 2 * self.config.overlap)]
+                    seq_length = len(sequence)
+    
+                    for i in range(num_chunks):
+                        # get chunk
+                        start_pos = i * chunk_length
+                        end_pos = min(seq_length, (i+1) * chunk_length + 2 * self.config.overlap)
+                        chunk_sequence = sequence[start_pos:end_pos]
+    
+                        # yield chunk
+                        yield key, {
+                            'sequence': chunk_sequence,
+                            'description': description,
+                            'start_pos': start_pos,
+                            'end_pos': end_pos,
+                        }
+                        key += 1</document_content>