Antibody Generation

AntibodyGPT: A Fine-Tuned GPT for De Novo Therapeutic Antibodies

• Web Demo
• Huggingface Model Repository

Antibodies are proteins that bind to a target protein (called an antigen) in order to mount an immune response. They are incredibly safe and effective therapeutics against infectious diseases, cancer, and autoimmune disorders.

Current antibody discovery methods require a lot of capital, expertise, and luck. Generative AI opens up the possibility of moving from a paradigm of antibody discovery to antibody generation. However, work is required to translate the advances of LLMs to the realm of drug discovery.

AntibodyGPT is a fine-tuned GPT language model that researchers can use to rapidly generate functional, diverse antibodies for any given target sequence